Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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Aquifex aeolicus VF5 Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: phytol + NAD+ = phytenal + NADH + H+ ,
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ = 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ = 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.3: L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ← dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.23: histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 3 H+ ,
1.1.1.25: shikimate + NADP+ ← 3-dehydroshikimate + NADPH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ = (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/4.1.1.3: oxaloacetate + H+ = pyruvate + CO2 ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ → pyruvate + CO2 + NADH ,
1.1.1.40: (S)-malate + NADP+ → CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH ,
1.1.1.42: D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.82: (S)-malate + NADP+ = oxaloacetate + NADPH + H+ ,
1.1.1.85: 3-ethylmalate + NAD+ = 2-oxovalerate + CO2 + NADH ,
1.1.1.85: (2R,3S)-3-isopropylmalate + NAD+ = 4-methyl-2-oxopentanoate + CO2 + NADH ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ ← (S)-2-acetolactate + NADPH + H+ ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+ ,
1.1.1.94: sn-glycerol 3-phosphate + NAD(P)+ ← dihydroxyacetone phosphate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.100: 3-oxo-docosapentaenoyl-CoA + NAD(P)H + H+ → 3-hydroxy-docosapentaenoyl-CoA + NAD(P)+ ,
1.1.1.101: 1-oleoyl-2-lyso-glycerone phosphate + NADPH + H+ → 1-oleyl-2-lyso-phosphatidate + NADP+ ,
1.1.1.169: (R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ ,
1.1.1.193: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+ ← 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ ,
1.1.1.202: 1,3-propanediol + NAD+ = 3-hydroxypropionaldehyde + NADH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.262: 4-phospho-hydroxy-L-threonine + NAD+ = 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NADH ,
1.1.1.267: 2-C-methyl-D-erythritol 4-phosphate + NADP+ ← 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ ,
1.1.1.282: shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+ ,
1.1.1.290: erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ ,
1.1.1.299: (S)-malate + NAD(P)+ = oxaloacetate + NAD(P)H + H+ ,
1.1.1.343: D-gluconate 6-phosphate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH ,
1.1.1.351: D-gluconate 6-phosphate + NAD(P)+ → D-ribulose 5-phosphate + CO2 + NAD(P)H ,
1.1.1.-: 1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
1.1.1.-: D-threo-isocitrate + NAD+ ← oxalosuccinate + NADH + H+ ,
1.1.5.3: sn-glycerol 3-phosphate[in] + an electron-transfer-related quinone → dihydroxyacetone phosphate[in] + an electron-transfer-related quinol ,
1.1.5.4: (S)-malate + a quinone → oxaloacetate + a quinol ,
1.1.5.4: (S)-malate + a menaquinone = oxaloacetate + a menaquinol ,
1.1.5.5: ethanol + an ubiquinone = acetaldehyde + an ubiquinol ,
1.1.5.-: (R)-lactate[in] + an electron-transfer-related quinone → pyruvate[in] + an electron-transfer-related quinol ,
1.1.99.33: formate + an oxidized electron acceptor + H+ = CO2 + a reduced electron acceptor ,
1.2.1.2: formate + NAD+ → CO2 + NADH ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O = 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O = a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O = an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: phytenal + NAD+ + H2O = phytenate + NADH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.4: acetaldehyde + NADP+ + H2O = acetate + NADPH + 2 H+ ,
1.2.1.7: benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ ,
1.2.1.9: D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ ↔ acetyl-CoA + NADH + H+ ,
1.2.1.11: L-aspartate-semialdehyde + NADP+ + phosphate ← L-aspartyl-4-phosphate + NADPH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.13: D-glyceraldehyde 3-phosphate + NADP+ + phosphate ← 1,3-bisphospho-D-glycerate + NADPH + H+ ,
1.2.1.22: L-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.28: benzaldehyde + NAD+ + H2O = benzoate + NADH + 2 H+ ,
1.2.1.38: an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde + NADP+ + phosphate ← an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.38: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate ← N-acetylglutamyl-phosphate + NADPH + H+ ,
1.2.1.41: L-glutamate-5-semialdehyde + NADP+ + phosphate ← L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.43: formate + NADP+ ← CO2 + NADPH ,
1.2.1.59: D-glyceraldehyde 3-phosphate + NAD(P)+ + phosphate = 1,3-bisphospho-D-glycerate + NAD(P)H + H+ ,
1.2.1.65: salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ ,
1.2.1.69: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.72: D-erythrose 4-phosphate + NAD+ + H2O → erythronate-4-phosphate + NADH + 2 H+ ,
1.2.1.-: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.3.1.12: prephenate + NAD+ → 4-hydroxyphenylpyruvate + CO2 + NADH ,
1.3.1.13: prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.76: precorrin-2 + NAD+ → sirohydrochlorin + NADH + 2 H+ ,
1.3.1.98: UDP-N-α-D-acetylmuramate + NADP+ ← UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.5.1: succinate[in] + an electron-transfer-related quinone → fumarate[in] + an electron-transfer-related quinol ,
1.3.5.1: succinate[in] + an ubiquinone → fumarate[in] + an ubiquinol ,
1.3.5.2: (S)-dihydroorotate[in] + an ubiquinone → orotate[in] + an ubiquinol ,
1.3.5.3: protoporphyrinogen IX + 3 a menaquinone → protoporphyrin IX + 3 a menaquinol ,
1.3.5.4: fumarate[in] + a rhodoquinol → succinate[in] + a rhodoquinone ,
1.3.5.4: fumarate[in] + a menaquinol → succinate[in] + a menaquinone ,
1.3.99.22: coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine ,
1.4.1.4: L-glutamate + NADP+ + H2O ← ammonium + 2-oxoglutarate + NADPH + H+ ,
1.4.1.13: 2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+ ,
1.4.1.14: 2 L-glutamate + NAD+ ← L-glutamine + 2-oxoglutarate + NADH + H+ ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.16: L-aspartate + oxygen → α-iminosuccinate + hydrogen peroxide + H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: tetrahydrofolate + NADP+ ← 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: 5,10-methylenetetrahydrofolate + NADP+ ↔ 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.15: 5,10-methylenetetrahydrofolate + NAD+ → 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: 5-methyl-tetrahydrofolate + NAD+ ← 5,10-methylenetetrahydrofolate + NADH + H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.3.1: sarcosine + oxygen + H2O → glycine + formaldehyde + hydrogen peroxide ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O → glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.99.-: L-aspartate + fumarate = α-iminosuccinate + succinate + H+ ,
1.6.5.3: NADH[in] + an ubiquinone + 5 H+[in] ↔ NAD+[in] + an ubiquinol + 4 H+[out] ,
1.6.5.9: NADH[in] + an ubiquinone + H+[in] → NAD+[in] + an ubiquinol ,
1.6.99.3: NADH + an oxidized electron acceptor + H+ = NAD+ + a reduced electron acceptor ,
1.7.1.1: nitrite + NAD+ + H2O = nitrate + NADH + H+ ,
1.7.1.2: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ ,
1.7.1.3: nitrite + NADP+ + H2O ← nitrate + NADPH + H+ ,
1.7.1.4: ammonium + 3 NAD(P)+ + 2 H2O ← nitrite + 3 NAD(P)H + 5 H+ ,
1.7.1.13: preQ1 + 2 NADP+ ← preQ0 + 2 NADPH + 3 H+ ,
1.7.5.1: nitrate[in] + a menaquinol + 2 H+[in] → nitrite[in] + a menaquinone + H2O[in] + 2 H+[out] ,
1.7.99.4: nitrate[out] + an ubiquinol → nitrite[out] + an ubiquinone + H2O[out] ,
1.7.99.4: nitrite + an oxidized electron acceptor + H2O = nitrate + a reduced electron acceptor ,
1.8.1.19: (sulfide)n + hydrogen sulfide + NADP+ = (sulfide)n+1 + NADPH + H+ ,
1.8.1.-: an alcohol + NAD+ + H2O ← an organic hydroperoxide + NADH + H+ ,
1.8.4.9: selenite + AMP + glutathione disulfide + 3 H+ ← adenosine 5'-phosphoselenate + 2 glutathione ,
1.8.5.3: dimethyl sulfoxide[out] + a menaquinol → dimethyl sulfide[out] + a menaquinone + H2O[out] ,
1.8.5.4: hydrogen sulfide + an electron-transfer-related quinone → intracellular S0 + an electron-transfer-related quinol ,
1.8.98.1: methanophenazine + coenzyme B + coenzyme M = CoB-CoM heterodisulfide + dihydromethanophenazine ,
1.10.3.11: 2 an ubiquinol + oxygen[in] → 2 an ubiquinone + 2 H2O[in] ,
1.10.3.14: 2 an ubiquinol + 4 H+[in] + oxygen[in] → 2 an ubiquinone + 4 H+[out] + 2 H2O[in] ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.12.1.2: NAD+ + H2 ↔ NADH + H+ ,
1.12.1.3: NADP+ + H2 ↔ NADPH + H+ ,
1.12.98.4: (sulfide)n + H2 → hydrogen sulfide + (sulfide)n-1 ,
1.12.99.6: a menaquinone + 2 H+[in] + H2[out] → a menaquinol + 2 H+[out] ,
1.12.99.6: an oxidized electron acceptor + H2 ↔ a reduced electron acceptor ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.55: 4 S0 + 4 H2O + oxygen → 2 hydrogen sulfide + 2 sulfite + 4 H+ ,
1.14.13.-: β-oxo-L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.17.1.2: dimethylallyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.2: isopentenyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.7.1: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + 2 an oxidized ferredoxin + H2O = 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + 2 a reduced ferredoxin + H+ ,
2.1.1.13: L-homocysteine + 5-methyl-tetrahydrofolate → L-methionine + tetrahydrofolate ,
2.1.1.14: L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate → L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.14: seleno-L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate + H+ = seleno-L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.19: trimethyl sulfonium + tetrahydrofolate ← dimethyl sulfide + 5-methyl-tetrahydrofolate + H+ ,
2.1.1.45: dUMP + 5,10-methylenetetrahydrofolate → dTMP + 7,8-dihydrofolate ,
2.1.1.79: a phospholipid olefinic fatty acid + S-adenosyl-L-methionine → a phospholipid cyclopropane fatty acid + S-adenosyl-L-homocysteine + H+ ,
2.1.1.107: 2 S-adenosyl-L-methionine + uroporphyrinogen-III → 2 S-adenosyl-L-homocysteine + precorrin-2 + H+ ,
2.1.1.148: dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ → dTMP + tetrahydrofolate + NADP+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor ,
2.1.1.-: 2-thio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.2.1: L-serine + tetrahydrofolate ↔ glycine + 5,10-methylenetetrahydrofolate + H2O ,
2.1.2.2: N1-(5-phospho-β-D-ribosyl)glycinamide + 10-formyl-tetrahydrofolate → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + tetrahydrofolate + H+ ,
2.1.2.3: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 10-formyl-tetrahydrofolate → 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide + tetrahydrofolate ,
2.1.2.11: 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O → 2-dehydropantoate + tetrahydrofolate ,
2.1.2.-: N1-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + ADP + phosphate + H+ ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate = L-citrulline + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate ↔ L-citrulline + phosphate + H+ ,
2.1.3.-: L-canaline + carbamoyl-phosphate = O-ureidohomoserine + phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.2.1.6: pyruvate + 2-oxobutanoate + H+ → (S)-2-aceto-2-hydroxybutanoate + CO2 ,
2.2.1.6: 2 pyruvate + H+ → (S)-2-acetolactate + CO2 ,
2.2.1.7: pyruvate + D-glyceraldehyde 3-phosphate + H+ → 1-deoxy-D-xylulose 5-phosphate + CO2 ,
2.3.1.1: L-glutamate + acetyl-CoA → N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.1: L-methionine + acetyl-CoA = N-α-acetyl-L-methionine + coenzyme A + H+ ,
2.3.1.8: acetyl-CoA + phosphate → acetyl phosphate + coenzyme A ,
2.3.1.15: sn-glycerol 3-phosphate + oleoyl-CoA → 1-oleyl-2-lyso-phosphatidate + coenzyme A ,
2.3.1.15: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = 1-C16:0-α,ω-dicaboxyl-2-lysophosphatidate + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.35: L-glutamate + N-acetyl-L-ornithine → N-acetyl-L-glutamate + L-ornithine ,
2.3.1.42: dihydroxyacetone phosphate + oleoyl-CoA → 1-oleoyl-2-lyso-glycerone phosphate + coenzyme A ,
2.3.1.47: a pimeloyl-[acp] + L-alanine + H+ = 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein] ,
2.3.1.47: pimeloyl-CoA + L-alanine + H+ → CO2 + 8-amino-7-oxononanoate + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.51: 1-oleyl-2-lyso-phosphatidate + oleoyl-CoA → 1-18:1-2-18:1-phosphatidate + coenzyme A ,
2.3.1.54: formate + acetyl-CoA ← pyruvate + coenzyme A ,
2.3.1.157: D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ ,
2.3.3.13: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+ ,
2.3.3.16: oxaloacetate + acetyl-CoA + H2O → citrate + coenzyme A + H+ ,
2.4.1.1: [(1→4)-α-D-glucosyl]n + phosphate = [(1→4)-α-D-glucosyl](n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: SHG-glucosyln+1 + phosphate = SHG-glucosyln + α-D-glucose 1-phosphate ,
2.4.1.1: maltoheptaose + phosphate = maltohexaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltohexaose + phosphate = maltopentaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltopentaose + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: maltotetraose + phosphate → maltotriose + α-D-glucose 1-phosphate ,
2.4.1.1: a linear malto-oligosaccharide [(glucose)n] + phosphate = α-D-glucose 1-phosphate + a linear malto-oligosaccharide [(glucose)n-1] ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = (1,4-α-D-glucosyl)(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin = (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.12: UDP-α-D-glucose + cellulose(n) = cellulose(n+1) + UDP ,
2.4.1.13: UDP-α-D-glucose + β-D-fructofuranose ← sucrose + UDP + H+ ,
2.4.1.14: UDP-α-D-glucose + β-D-fructofuranose 6-phosphate → sucrose 6F-phosphate + UDP + H+ ,
2.4.1.18: a 1,4-α-D-glucan → a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = a (1,6)-α-D-glucosyl-(1,4)-α-glucan highly branched + n H2O ,
2.4.1.18: n α-amylose = n amylopectin + n H2O ,
2.4.1.18: a glucosylated glycogenin = a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.21: ADP-α-D-glucose + (1,4-α-D-glucosyl)(n) → ADP + (1,4-α-D-glucosyl)(n+1) ,
2.4.1.25: a long-linear glucan + α-D-glucose = a short glucan + a short glucan ,
2.4.1.25: SHG-glucosyln+1 + β-D-glucose = SHG-glucosyln + maltose ,
2.4.1.25: maltohexaose + β-D-glucose = maltopentaose + maltose ,
2.4.1.25: maltopentaose + D-glucopyranose = maltotetraose + maltose ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.25: a glucan + D-glucopyranose = a glucan + maltotriose ,
2.4.1.25: a maltodextrin(n+1) + α-D-glucose = a maltodextrin(n) + maltose ,
2.4.1.25: maltotetraose + D-glucopyranose ← maltotriose + maltose ,
2.4.1.29: cellulose(n) + GDP-α-D-glucose = GDP + (1,4-β-D-glucosyl)(n+1) ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-pentapeptide]n-diphosphoundecaprenol + a lipid II → [GlcNAc-(1->4)-MurNAc-pentapeptide](n+1)-diphosphoundecaprenol + di-trans,octa-cis-undecaprenyl diphosphate ,
2.4.1.129: 2 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → a peptidoglycan dimer (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine]n-diphosphoundecaprenol + undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → di-trans,octa-cis-undecaprenyl diphosphate + [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine](n+1)-diphosphoundecaprenol ,
2.4.1.182: 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+ ,
2.4.1.227: undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-α-D-glucosamine → undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+ ,
2.4.1.227: decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UDP-N-acetyl-α-D-glucosamine → decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) + UDP + H+ ,
2.4.1.-: 2 decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) → a peptidoglycan dimer (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
2.4.2.1: a purine ribonucleoside + arsenate = a purine base + ribose-1-arsenate ,
2.4.2.1: a purine 2'-deoxyribonucleoside + phosphate = a purine base + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 5'-deoxy-5'-fluoroadenosine + phosphate = adenine + 5-fluoro-5-deoxy-D-ribose 1-phosphate ,
2.4.2.1: 5'-deoxy-5'-chloroadenosine + phosphate = 5-chloro-5-deoxyribose 1-phosphate + adenine ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyadenosine + phosphate → adenine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: adenosine + phosphate ↔ adenine + α-D-ribose-1-phosphate ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: a purine ribonucleoside + phosphate = a purine base + α-D-ribose-1-phosphate ,
2.4.2.1: inosine + phosphate → hypoxanthine + α-D-ribose-1-phosphate ,
2.4.2.7: AMP + diphosphate ← adenine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← hypoxanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.9: UMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate → guanine + α-D-ribose-1-phosphate ,
2.4.2.17: 1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ← ATP + 5-phospho-α-D-ribose 1-diphosphate + H+ ,
2.4.2.18: N-(5-phosphoribosyl)-anthranilate + diphosphate ← anthranilate + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.22: XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.-: phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+ ,
2.5.1.3: 4-methyl-5-(2-phosphonooxyethyl)thiazole + 4-amino-2-methyl-5-diphosphomethylpyrimidine + H+ → thiamin phosphate + diphosphate ,
2.5.1.3: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.3: 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.7: UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate → UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate ,
2.5.1.9: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin ,
2.5.1.15: 4-aminobenzoate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate → 7,8-dihydropteroate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.19: shikimate 3-phosphate + phosphoenolpyruvate → 5-enolpyruvyl-shikimate 3-phosphate + phosphate ,
2.5.1.29: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.39: all-trans-octaprenyl diphosphate + 4-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.54: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate ,
2.5.1.55: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.72: α-iminosuccinate + dihydroxyacetone phosphate → quinolinate + phosphate + 2 H2O ,
2.5.1.78: 5-amino-6-(D-ribitylamino)uracil + 1-deoxy-L-glycero-tetrulose 4-phosphate → 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + H+ + 2 H2O ,
2.5.1.105: 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = 7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphate + 2 H+ ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ L-glutamate + oxaloacetate ,
2.6.1.1: L-phenylalanine + 2-oxoglutarate ↔ 2-oxo-3-phenylpropanoate + L-glutamate ,
2.6.1.1: L-cysteate + 2-oxoglutarate = 3-sulfopyruvate + L-glutamate ,
2.6.1.1: L-aspartate + 2-oxoglutarate = L-glutamate + oxaloacetate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate ← L-glutamate + 4-methyl-2-oxopentanoate ,
2.6.1.9: imidazole acetol-phosphate + L-glutamate → L-histidinol-phosphate + 2-oxoglutarate ,
2.6.1.11: an [L-2-aminoadipate carrier protein]-L-ornithine + 2-oxoglutarate ↔ L-glutamate + an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde ,
2.6.1.11: N-acetyl-L-ornithine + 2-oxoglutarate ← L-glutamate + N-acetyl-L-glutamate 5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate ← L-glutamate + (S)-3-methyl-2-oxopentanoate ,
2.6.1.42: L-valine + 2-oxoglutarate ↔ L-glutamate + 3-methyl-2-oxobutanoate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate → 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← L-glutamate + 3-phospho-hydroxypyruvate ,
2.6.1.57: L-tyrosine + 2-oxoglutarate ← 4-hydroxyphenylpyruvate + L-glutamate ,
2.6.1.62: S-adenosyl-L-methionine + 8-amino-7-oxononanoate ↔ S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminopelargonate ,
2.6.1.66: pyruvate + L-valine → L-alanine + 3-methyl-2-oxobutanoate ,
2.6.1.85: chorismate + L-glutamine → 4-amino-4-deoxychorismate + L-glutamate ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.99.2: 1-deoxy-D-xylulose 5-phosphate + 3-amino-1-hydroxyacetone 1-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.4: β-D-fructofuranose + ATP → β-D-fructofuranose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate = ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → phosphoadenosine-5'-phosphosulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → D-4'-phosphopantothenate + ADP + H+ ,
2.7.1.39: L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ ,
2.7.1.40: pyruvate + ATP ↔ phosphoenolpyruvate + ADP + H+ ,
2.7.1.49: ATP + hydroxymethylpyrimidine → ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine + H+ ,
2.7.1.50: ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ ,
2.7.1.66: di-trans,octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+ ,
2.7.1.71: shikimate + ATP → shikimate 3-phosphate + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.130: lipid A disaccharide + ATP → lipid IVA + ADP + H+ ,
2.7.1.146: β-D-fructofuranose 6-phosphate + ADP ← fructose 1,6-bisphosphate + AMP + H+ ,
2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP → 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP + H+ ,
2.7.1.170: 1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ ,
2.7.2.1: ATP + acetate ← ADP + acetyl phosphate ,
2.7.2.2: ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.4: L-aspartate + ATP → L-aspartyl-4-phosphate + ADP ,
2.7.2.8: an [L-2-aminoadipate carrier protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + ADP ,
2.7.2.8: N-acetyl-L-glutamate + ATP → N-acetylglutamyl-phosphate + ADP ,
2.7.2.11: L-glutamate + ATP → L-glutamate 5-phosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: ATP + dIDP = ADP + dITP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: ATP + IDP = ITP + ADP ,
2.7.4.6: GDP + ADP = GTP + AMP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.7: 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP → 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.12/2.7.4.13: ATP + dTMP → ADP + dTDP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.13: dGMP + ATP → dGDP + ADP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.16: thiamin phosphate + ATP → thiamin diphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.5: ATP + GDP → AMP + ppGpp ,
2.7.6.5: GTP + ATP → pppGpp + AMP ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.4: selenate + ATP + 2 H+ → adenosine 5'-phosphoselenate + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ ↔ UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.18: β-nicotinate D-ribonucleotide + ATP + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.24: α-D-glucose 1-phosphate + dTTP + H+ = dTDP-α-D-glucose + diphosphate ,
2.7.7.27: α-D-glucose 1-phosphate + ATP + H+ → ADP-α-D-glucose + diphosphate ,
2.7.7.38: 3-deoxy-D-manno-octulosonate + CTP = CMP-3-deoxy-D-manno-octulosonate + diphosphate ,
2.7.7.39: sn-glycerol 3-phosphate + CTP + H+ = CDP-glycerol + diphosphate ,
2.7.7.41: CTP + a 2,3,4-saturated L-phosphatidate + H+ → a CDP-2,3,4-saturated-diacylglycerol + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate → a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate + CTP + H+ → 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate → undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP ,
2.7.8.-: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + trans,octacis-decaprenyl phosphate → decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UMP ,
2.7.9.2: pyruvate + ATP + H2O → phosphoenolpyruvate + AMP + phosphate + 2 H+ ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.8.1.1: a sulfurated [sulfur carrier] + hydrogen cyanide → an unsulfurated [sulfur carrier] + thiocyanate + 2 H+ ,
2.8.1.1: thiosulfate + hydrogen cyanide → sulfite + thiocyanate + 2 H+ ,
2.8.1.6: a sulfurated [sulfur carrier] + dethiobiotin + 2 S-adenosyl-L-methionine → an unsulfurated [sulfur carrier] + biotin + 2 5'-deoxyadenosine + 2 L-methionine ,
2.8.1.7: an [L-cysteine desulfurase] + L-cysteine → an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.-: N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine + a sulfurated [sulfur carrier] = 2-thio-N6-dimethylallyladenosine37 in tRNA + an unsulfurated [sulfur carrier] + L-methionine + 5'-deoxyadenosine ,
2.8.4.3: N6-dimethylallyladenosine37 in tRNA + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier] → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + an unsulfurated [sulfur carrier] + H+ ,
2.-.-.-: heptosyl-Kdo2-lipid A + ADP-L-glycero-β-D-manno-heptose = (heptosyl)2-Kdo2-lipid A + ADP + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.15: L-histidinol-phosphate + H2O → histidinol + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.24: sucrose 6F-phosphate + H2O → sucrose + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.7.2: pppGpp + H2O → GTP + diphosphate + H+ ,
3.1.7.2: ppGpp + H2O → GDP + diphosphate + H+ ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.21.2: a single stranded DNA + n H2O → n a 5'-phosphooligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.2.1: guanosine + H2O → D-ribofuranose + guanine ,
3.2.2.9: S-adenosyl-L-homocysteine + H2O → S-ribosyl-L-homocysteine + adenine ,
3.2.2.14: β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.4.11.18: a peptide with N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.16.4: 2 a peptidoglycan dimer (meso-diaminopimelate containing) → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine ,
3.4.17.13: L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine ,
3.4.21.50: a protein + H2O → a peptide + a peptide ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.5.1.10: 10-formyl-tetrahydrofolate + H2O → formate + tetrahydrofolate + H+ ,
3.5.1.16: N-acetyl-L-ornithine + H2O → L-ornithine + acetate ,
3.5.1.18: N-succinyl-L,L-2,6-diaminopimelate + H2O = L,L-diaminopimelate + succinate ,
3.5.1.19: nicotinamide + H2O → ammonium + nicotinate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.28: N-acetylmuramoyl-L-alaninate + H2O = N-acetylmuramate + L-alanine ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.31: N-formyl-L-methionine + H2O = L-methionine + formate ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.42: β-nicotinamide D-ribonucleotide + H2O → ammonium + β-nicotinate D-ribonucleotide ,
3.5.1.59: N-carbamoylsarcosine + 2 H+ + H2O → ammonium + CO2 + sarcosine ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.108: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + H2O → UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine + acetate ,
3.5.1.-: an [L-2-aminoadipate carrier protein]-L-ornithine + H2O → L-ornithine + a [LysW protein]-L-glutamate ,
3.5.1.-: pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.6: a β-lactam + H2O = a substituted β-amino acid ,
3.5.2.14: N-methylhydantoin + ATP + 2 H2O → N-carbamoylsarcosine + ADP + phosphate + 2 H+ ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.9: 5,10-methenyltetrahydrofolate + H2O ↔ 10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.13: CTP + H+ + H2O = UTP + ammonium ,
3.5.4.13: dCTP + H+ + H2O → ammonium + dUTP ,
3.5.4.16: GTP + H2O = formate + 7,8-dihydroneopterin triphosphate + H+ ,
3.5.4.19: 1-(5-phospho-β-D-ribosyl)-AMP + H2O → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ,
3.5.4.21: creatinine + H+ + H2O → ammonium + N-methylhydantoin ,
3.5.4.25: GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+ ,
3.5.4.26: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ + H2O → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.11: (polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.22: NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ ,
3.6.1.31: 1-(5-phospho-β-D-ribosyl)-ATP + H2O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H+ ,
3.6.1.40: pppGpp + H2O → ppGpp + phosphate + H+ ,
3.6.1.41: 5',5'''-diadenosine tetraphosphate + H2O = 2 ADP + 2 H+ ,
3.6.1.54: UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.14: ATP + 4 H+[in] + H2O ↔ ADP + phosphate + 5 H+[out] ,
3.6.3.27: ATP + phosphate[periplasmic space] + H2O → ADP + 2 phosphate[cytosol] + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
4.1.1.11: L-aspartate + H+ = β-alanine + CO2 ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.20: meso-diaminopimelate + H+ = CO2 + L-lysine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.31: oxaloacetate + phosphate ← phosphoenolpyruvate + hydrogen carbonate ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → coproporphyrinogen III + 4 CO2 ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.48: 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O ,
4.1.1.49: oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.72: 3-methyl-2-oxobutanoate + H+ → isobutanal + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.8: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate → indole + D-glyceraldehyde 3-phosphate ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.17: L-fuculose 1-phosphate = L-lactaldehyde + dihydroxyacetone phosphate ,
4.1.2.-: DL-allothreonine = acetaldehyde + glycine ,
4.1.3.27: chorismate + L-glutamine → anthranilate + L-glutamate + pyruvate + H+ ,
4.1.3.34: (3S)-citryl-CoA → oxaloacetate + acetyl-CoA ,
4.1.3.38: 4-amino-4-deoxychorismate → 4-aminobenzoate + pyruvate + H+ ,
4.1.99.12: D-ribulose 5-phosphate → formate + 1-deoxy-L-glycero-tetrulose 4-phosphate + H+ ,
4.1.99.17: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + carbon monoxide + 3 H+ ,
4.1.99.19: L-tyrosine + S-adenosyl-L-methionine + a reduced electron acceptor → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + an oxidized electron acceptor + 2 H+ ,
4.2.1.1: hydrogen carbonate + H+ ← CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.3: citrate = D-threo-isocitrate ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylbutanoate → 3-methyl-2-oxobutanoate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylpentanoate → (S)-3-methyl-2-oxopentanoate + H2O ,
4.2.1.10: 3-dehydroquinate → 3-dehydroshikimate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.19: D-erythro-imidazole-glycerol-phosphate → imidazole acetol-phosphate + H2O ,
4.2.1.20: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O ,
4.2.1.24: 2 5-amino-levulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.33: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate ,
4.2.1.47: GDP-α-D-mannose = GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.51: prephenate + H+ = 2-oxo-3-phenylpropanoate + CO2 + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.104: cyanate + hydrogen carbonate + H+ → carbamate + CO2 ,
4.2.1.104: cyanate + hydrogen carbonate + 3 H+ = ammonium + 2 CO2 ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl phosphate + H2O ,
4.2.1.122: L-serine + indole → L-tryptophan + H2O ,
4.2.1.126: N-acetyl-β-muramate 6-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + (R)-lactate ,
4.2.1.-: 5-chloro-5-deoxy-D-ribonate = 5-chloro-4-hydroxy-2-oxopentanoate + H2O ,
4.2.3.1: O-phospho-L-homoserine + H2O → L-threonine + phosphate ,
4.2.3.4: 3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate ,
4.2.3.5: 5-enolpyruvyl-shikimate 3-phosphate → chorismate + phosphate ,
4.3.2.1: canavaninosuccinate = L-canavanine + fumarate ,
4.3.2.1: L-arginino-succinate → L-arginine + fumarate ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.3.7: pyruvate + L-aspartate-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ ,
4.4.1.21: S-ribosyl-L-homocysteine → L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.12: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol → 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + CMP ,
4.99.1.1: protoporphyrin IX + Fe2+ → protoheme IX + 2 H+ ,
4.99.1.4: sirohydrochlorin + Fe2+ → siroheme + 2 H+ ,
5.1.1.1: L-alanine → D-alanine ,
5.1.1.3: L-glutamate → D-glutamate ,
5.1.1.7: L,L-diaminopimelate = meso-diaminopimelate ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.20: ADP-D-glycero-β-D-manno-heptose = ADP-L-glycero-β-D-manno-heptose ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate → β-D-fructofuranose 6-phosphate ,
5.3.1.16: 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide → phosphoribulosylformimino-AICAR-P ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.1.24: N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate ,
5.3.1.28: D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H+ ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.14: a trans2-decenoyl-[acp] → a cis3-decenoyl-[acp] ,
5.3.99.10: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate → 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate = D-glucopyranose 6-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.10: D-glucosamine 1-phosphate ← D-glucosamine 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.2.12: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.3.8: glutamate-1-semialdehyde → 5-amino-levulinate ,
5.4.99.5: chorismate → prephenate ,
5.4.99.18: N5-carboxyaminoimidazole ribonucleotide → 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.3: eicosapentaenoate + ATP + coenzyme A → eicosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.4: itaconate + GTP + coenzyme A → itaconyl-CoA + GDP + phosphate ,
6.2.1.4: succinate + GTP + coenzyme A ↔ succinyl-CoA + GDP + phosphate ,
6.2.1.5: succinate + ATP + coenzyme A ↔ succinyl-CoA + ADP + phosphate ,
6.2.1.14: pimelate + ATP + coenzyme A → pimeloyl-CoA + AMP + diphosphate ,
6.2.1.18: citrate + ATP + coenzyme A → (3S)-citryl-CoA + ADP + phosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.5: ammonium + ATP + nicotinate adenine dinucleotide → AMP + NAD+ + diphosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + ADP + phosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + AMP + diphosphate + H+ ,
6.3.2.4: 2 D-alanine + ATP → D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.8: L-alanine + UDP-N-α-D-acetylmuramate + ATP → UDP-N-acetylmuramoyl-L-alanine + ADP + phosphate + H+ ,
6.3.2.9: UDP-N-acetylmuramoyl-L-alanine + D-glutamate + ATP → UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + ADP + phosphate + H+ ,
6.3.2.10: UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + D-alanyl-D-alanine + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.12: L-glutamate + 7,8-dihydropteroate + ATP → ADP + 7,8-dihydrofolate + phosphate + H+ ,
6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: UDP-N-α-D-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.-: L-glutamate + a [LysW protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate + ADP + phosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: ATP + 5-formyl-tetrahydrofolate → 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.3.3: CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+ ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: ATP + formate + tetrahydrofolate → ADP + 10-formyl-tetrahydrofolate + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: O-ureidohomoserine + L-aspartate + ATP → canavaninosuccinate + AMP + diphosphate + H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.13: 5-phospho-β-D-ribosylamine + ATP + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.18: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + hydrogen carbonate → N5-carboxyaminoimidazole ribonucleotide + ADP + phosphate + 2 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + carbamoyl-phosphate + 2 ADP + phosphate + 2 H+ ,
6.4.1.1: pyruvate + hydrogen carbonate + ATP → oxaloacetate + ADP + phosphate + H+ ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.7: ATP + 2-oxoglutarate + CO2 + H2O → oxalosuccinate + ADP + phosphate + 2 H+ ,
6.5.1.1: (deoxynucleotides)(m) + ATP + (deoxynucleotides)n → AMP + (deoxynucleotides)(n+m) + diphosphate ,
6.5.1.2: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
glutathioselenol + NADPH + 2 H+ → hydrogen selenide + glutathione + NADP+ ,
selenodiglutathione + NADPH → glutathioselenol + glutathione + NADP+ ,
glycine + oxygen → 2-iminoacetate + hydrogen peroxide + H+ ,
an S-sulfanyl-[L-cysteine desulfurase] + a ThiI sulfur-carrier protein → an [L-cysteine desulfurase] + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
glycine + tetrahydrofolate + NAD+ → ammonium + CO2 + 5,10-methylenetetrahydrofolate + NADH ,
n S0 + HS- → (sulfide)n+1 + H+ ,
formate + H+ → CO2 + H2 ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate + H+ ,
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with L,D cross-links (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + 4 D-alanine + H+ ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with D,D cross-links (mycobacteria) + 4 D-alanine + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
ammonium[out] → ammonium[in] ,
nitrate[out] + 2 H+[out] + 2 e- → nitrite[out] + H2O[out] ,
(2R,3S)-3-isopropylmalate + NAD+ → (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ ,
(2S)-2-isopropyl-3-oxosuccinate + H+ → 4-methyl-2-oxopentanoate + CO2 ,
5 S0 + oxygen + 4 H2O → sulfite + thiosulfate + 2 hydrogen sulfide + 3 H+ ,
deethylsimazine + H2O = N-ethylammeline + chloride + H+ ,
ribose-1-arsenate + dihydrolipoate + H+ = D-ribofuranose + arsenite + (R)-lipoate ,
2-oxoglutarate + coenzyme A + NAD+ → succinyl-CoA + CO2 + NADH ,
histidinol + NAD+ → histidinal + NADH + H+ ,
histidinal + NAD+ + H2O → L-histidine + NADH + 2 H+ ,
4-phospho-hydroxy-L-threonine + NAD+(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+ ,
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + H+ → 3-amino-1-hydroxyacetone 1-phosphate + CO2 ,
a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP = a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
dimethyl sulfoxide + NADH + H+ = dimethyl sulfide + NAD+ + H2O ,
4 H+[in] → 4 H+[out] ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+ ,
S-adenosyl-L-methionine + precorrin-1 → S-adenosyl-L-homocysteine + precorrin-2 ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
carbamate + 2 H+ → ammonium + CO2 ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
(2R,3S)-3-isopropylmalate ← 2-isopropylmaleate + H2O ,
(2S)-2-isopropylmalate → 2-isopropylmaleate + H2O ,
ATP + UTP + ammonium = ADP + CTP + phosphate + 2 H+ ,
citrate ↔ cis-aconitate + H2O ,
cis-aconitate + H2O ↔ D-threo-isocitrate ,
Mg2+[periplasmic space] → Mg2+[cytosol] ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
aldehydo-D-ribose ↔ D-ribopyranose ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
sulfite + H+ ↔ bisulfite ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
(S)-2-acetolactate + an oxidized electron acceptor + H+ → diacetyl + CO2 + a reduced electron acceptor ,
formaldehyde + tetrahydrofolate → 5,10-methylenetetrahydrofolate + H2O ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
aldehydo-D-ribose ↔ D-ribofuranose ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
glutathione + S0 → S-sulfanylglutathione ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
2-iminoacetate + H+ + H2O → glyoxylate + ammonium ,
NADH + H2O → (R)-NADHX ,
NADH + H2O → (S)-NADHX ,
ammonia + H+ ↔ ammonium ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
(S)-4,5-dihydroxypentan-2,3-dione → (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
(S)-4,5-dihydroxypentan-2,3-dione → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ = 3-amino-4,7-dihydroxy-coumarin + a NovH peptidyl-carrier protein + NADPH + H+


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