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Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
Pathway Tools
Intro Tutorial
discounted registration ends Sept 5, 2015 (Sat)
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Aquifex aeolicus VF5 Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ = 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ = 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: phytol + NAD+ = phytenal + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.3: L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ← dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.23: histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 3 H+ ,
1.1.1.25: shikimate + NADP+ ← 3-dehydroshikimate + NADPH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ = (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ → pyruvate + CO2 + NADH ,
1.1.1.38/4.1.1.3: oxaloacetate + H+ = pyruvate + CO2 ,
1.1.1.40: (S)-malate + NADP+ → CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH ,
1.1.1.42: D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.82: (S)-malate + NADP+ = oxaloacetate + NADPH + H+ ,
1.1.1.85: (2R,3S)-3-isopropylmalate + NAD+ = 4-methyl-2-oxopentanoate + CO2 + NADH ,
1.1.1.85: 3-ethylmalate + NAD+ = 2-oxovalerate + CO2 + NADH ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+ ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ ← (S)-2-acetolactate + NADPH + H+ ,
1.1.1.94: sn-glycerol 3-phosphate + NAD(P)+ ← dihydroxyacetone phosphate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.100: 3-oxo-docosapentaenoyl-CoA + NAD(P)H + H+ → 3-hydroxy-docosapentaenoyl-CoA + NAD(P)+ ,
1.1.1.101: 1-oleoyl-2-lyso-glycerone phosphate + NADPH + H+ → 1-oleyl-2-lyso-phosphatidate + NADP+ ,
1.1.1.169: (R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ ,
1.1.1.193: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+ ← 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ ,
1.1.1.202: 1,3-propanediol + NAD+ = 3-hydroxypropionaldehyde + NADH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.262: 4-phospho-hydroxy-L-threonine + NAD+ = 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NADH ,
1.1.1.267: 2-C-methyl-D-erythritol 4-phosphate + NADP+ ← 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ ,
1.1.1.282: shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+ ,
1.1.1.290: erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ ,
1.1.1.299: (S)-malate + NAD(P)+ = oxaloacetate + NAD(P)H + H+ ,
1.1.1.343: D-gluconate 6-phosphate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH ,
1.1.1.351: D-gluconate 6-phosphate + NAD(P)+ → D-ribulose 5-phosphate + CO2 + NAD(P)H ,
1.1.1.-: D-threo-isocitrate + NAD+ ← oxalosuccinate + NADH + H+ ,
1.1.1.-: 1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
1.1.5.3: sn-glycerol 3-phosphate[in] + an electron-transfer quinone[membrane] → dihydroxyacetone phosphate[in] + an electron-transfer quinol[membrane] ,
1.1.5.4: (S)-malate + a menaquinone = oxaloacetate + a menaquinol ,
1.1.5.4: (S)-malate[membrane] + a quinone[membrane] → oxaloacetate[membrane] + a quinol[membrane] ,
1.1.5.5: ethanol + an ubiquinone = acetaldehyde + an ubiquinol ,
1.1.5.-: (R)-lactate[in] + an electron-transfer quinone[membrane] → pyruvate[in] + an electron-transfer quinol[membrane] ,
1.1.99.33: formate + an unknown oxidized electron acceptor + H+ = CO2 + an unknown reduced electron acceptor ,
1.2.1.2: formate + NAD+ → CO2 + NADH ,
1.2.1.3: phytenal + NAD+ + H2O = phytenate + NADH + 2 H+ ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O = an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O = a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O = 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.4: acetaldehyde + NADP+ + H2O = acetate + NADPH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.7: benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ ,
1.2.1.9: D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ ↔ acetyl-CoA + NADH + H+ ,
1.2.1.11: L-aspartate-semialdehyde + NADP+ + phosphate ← L-aspartyl-4-phosphate + NADPH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.13: D-glyceraldehyde 3-phosphate + NADP+ + phosphate ← 1,3-bisphospho-D-glycerate + NADPH + H+ ,
1.2.1.22: L-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.28: benzaldehyde + NAD+ + H2O = benzoate + NADH + 2 H+ ,
1.2.1.38: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate ← N-acetylglutamyl-phosphate + NADPH + H+ ,
1.2.1.38: an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde + NADP+ + phosphate ← an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.41: L-glutamate-5-semialdehyde + NADP+ + phosphate ← L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.43: formate + NADP+ ← CO2 + NADPH ,
1.2.1.59: D-glyceraldehyde 3-phosphate + NAD(P)+ + phosphate = 1,3-bisphospho-D-glycerate + NAD(P)H + H+ ,
1.2.1.65: salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ ,
1.2.1.69: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.72: D-erythrose 4-phosphate + NAD+ + H2O → erythronate-4-phosphate + NADH + 2 H+ ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.2.1.-: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
1.3.1.12: prephenate + NAD+ → 4-hydroxyphenylpyruvate + CO2 + NADH ,
1.3.1.13: prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.76: precorrin-2 + NAD+ → sirohydrochlorin + NADH + 2 H+ ,
1.3.1.98: UDP-N-α-D-acetylmuramate + NADP+ ← UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.5.1: succinate[in] + an ubiquinone[membrane] → fumarate[in] + an ubiquinol[membrane] ,
1.3.5.1: succinate[in] + an electron-transfer quinone[membrane] → fumarate[in] + an electron-transfer quinol[membrane] ,
1.3.5.2: (S)-dihydroorotate[in] + an ubiquinone[membrane] → orotate[in] + an ubiquinol[membrane] ,
1.3.5.3: protoporphyrinogen IX[membrane] + 3 a menaquinone[membrane] → protoporphyrin IX[membrane] + 3 a menaquinol[membrane] ,
1.3.5.4: fumarate[in] + a menaquinol[membrane] → succinate[in] + a menaquinone[membrane] ,
1.3.5.4: fumarate[in] + a rhodoquinol[membrane] → succinate[in] + a rhodoquinone[membrane] ,
1.3.99.22: coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine ,
1.4.1.4: L-glutamate + NADP+ + H2O ← ammonium + 2-oxoglutarate + NADPH + H+ ,
1.4.1.13: 2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+ ,
1.4.1.14: 2 L-glutamate + NAD+ ← L-glutamine + 2-oxoglutarate + NADH + H+ ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.16: L-aspartate + oxygen → α-iminosuccinate + hydrogen peroxide + H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: tetrahydrofolate + NADP+ ← 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: 5,10-methylenetetrahydrofolate + NADP+ ↔ 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.15: 5,10-methylenetetrahydrofolate + NAD+ → 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: 5-methyl-tetrahydrofolate + NAD+ ← 5,10-methylenetetrahydrofolate + NADH + H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.3.1: sarcosine + oxygen + H2O → glycine + formaldehyde + hydrogen peroxide ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O → glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.99.-: L-aspartate + fumarate = α-iminosuccinate + succinate + H+ ,
1.6.5.3: NADH[in] + an ubiquinone[membrane] + 5 H+[in] ↔ NAD+[in] + an ubiquinol[membrane] + 4 H+[out] ,
1.6.5.9: NADH[in] + an ubiquinone[membrane] + H+[in] → NAD+[in] + an ubiquinol[membrane] ,
1.6.99.3: NADH + an unknown oxidized electron acceptor + H+ = NAD+ + an unknown reduced electron acceptor ,
1.7.1.1: nitrite + NAD+ + H2O = nitrate + NADH + H+ ,
1.7.1.2: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ ,
1.7.1.3: nitrite + NADP+ + H2O ← nitrate + NADPH + H+ ,
1.7.1.4: ammonium + 3 NAD(P)+ + 2 H2O ← nitrite + 3 NAD(P)H + 5 H+ ,
1.7.1.13: preQ1 + 2 NADP+ ← preQ0 + 2 NADPH + 3 H+ ,
1.7.5.1: nitrate[in] + a menaquinol[membrane] + 2 H+[in] → nitrite[in] + a menaquinone[membrane] + H2O[in] + 2 H+[out] ,
1.7.99.4: nitrite + an unknown oxidized electron acceptor + H2O = nitrate + an unknown reduced electron acceptor ,
1.7.99.4: nitrate[out] + an ubiquinol[membrane] → nitrite[out] + an ubiquinone[membrane] + H2O[out] ,
1.8.1.19: (sulfide)n + hydrogen sulfide + NADP+ = (sulfide)n+1 + NADPH + H+ ,
1.8.1.-: an organic hydroperoxide + NADH + H+ → an alcohol + NAD+ + H2O ,
1.8.4.9: selenite + AMP + glutathione disulfide + 3 H+ ← adenosine 5'-phosphoselenate + 2 glutathione ,
1.8.5.3: dimethyl sulfoxide[out] + a menaquinol[membrane] → dimethyl sulfide[out] + a menaquinone[membrane] + H2O[out] ,
1.8.5.4: hydrogen sulfide + an electron-transfer quinone → intracellular S0 + an electron-transfer quinol ,
1.8.98.1: methanophenazine + coenzyme B + coenzyme M = CoB-CoM heterodisulfide + dihydromethanophenazine ,
1.10.3.11: 2 an ubiquinol[membrane] + oxygen[in] → 2 an ubiquinone[membrane] + 2 H2O[in] ,
1.10.3.14: 2 an ubiquinol[membrane] + 4 H+[in] + oxygen[in] → 2 an ubiquinone[membrane] + 4 H+[out] + 2 H2O[in] ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.12.1.2: NAD+ + H2 ↔ NADH + H+ ,
1.12.1.3: NADP+ + H2 ↔ NADPH + H+ ,
1.12.98.4: (sulfide)n + H2 → hydrogen sulfide + (sulfide)n-1 ,
1.12.99.6: an unknown oxidized electron acceptor + H2 ↔ an unknown reduced electron acceptor ,
1.12.99.6: a menaquinone[membrane] + 2 H+[in] + H2[out] → a menaquinol[membrane] + 2 H+[out] ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.55: 4 S0 + 4 H2O + oxygen → 2 hydrogen sulfide + 2 sulfite + 4 H+ ,
1.14.13.-: β-oxo-L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.17.1.2: isopentenyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.2: dimethylallyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.7.1: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + 2 an oxidized ferredoxin + H2O ← 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + 2 a reduced ferredoxin + H+ ,
2.1.1.13: L-homocysteine + 5-methyl-tetrahydrofolate → L-methionine + tetrahydrofolate ,
2.1.1.14: seleno-L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate + H+ = seleno-L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.14: L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate → L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.19: trimethyl sulfonium + tetrahydrofolate ← dimethyl sulfide + 5-methyl-tetrahydrofolate + H+ ,
2.1.1.45: dUMP + 5,10-methylenetetrahydrofolate → dTMP + 7,8-dihydrofolate ,
2.1.1.79: a [phospholipid] olefinic fatty acid + S-adenosyl-L-methionine → a [phospholipid] cyclopropane fatty acid + S-adenosyl-L-homocysteine + H+ ,
2.1.1.107: 2 S-adenosyl-L-methionine + uroporphyrinogen-III → 2 S-adenosyl-L-homocysteine + precorrin-2 + H+ ,
2.1.1.148: dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ → dTMP + tetrahydrofolate + NADP+ ,
2.1.1.-: 2-thio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl donor → S-adenosyl-L-homocysteine + a methylated methyl donor ,
2.1.2.1: L-serine + tetrahydrofolate ↔ glycine + 5,10-methylenetetrahydrofolate + H2O ,
2.1.2.2: N1-(5-phospho-β-D-ribosyl)glycinamide + 10-formyl-tetrahydrofolate → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + tetrahydrofolate + H+ ,
2.1.2.3: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 10-formyl-tetrahydrofolate → 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide + tetrahydrofolate ,
2.1.2.11: 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O → 2-dehydropantoate + tetrahydrofolate ,
2.1.2.-: N1-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + ADP + phosphate + H+ ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate ↔ L-citrulline + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate = L-citrulline + phosphate + H+ ,
2.1.3.-: L-canaline + carbamoyl-phosphate = O-ureidohomoserine + phosphate ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.2.1.6: 2 pyruvate + H+ → (S)-2-acetolactate + CO2 ,
2.2.1.6: pyruvate + 2-oxobutanoate + H+ → (S)-2-aceto-2-hydroxybutanoate + CO2 ,
2.2.1.7: pyruvate + D-glyceraldehyde 3-phosphate + H+ → 1-deoxy-D-xylulose 5-phosphate + CO2 ,
2.3.1.1: L-methionine + acetyl-CoA = N-α-acetyl-L-methionine + coenzyme A + H+ ,
2.3.1.1: L-glutamate + acetyl-CoA → N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.8: acetyl-CoA + phosphate → acetyl phosphate + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.15: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = 1-C16:0-α,ω-dicaboxyl-2-lysophosphatidate + coenzyme A ,
2.3.1.15: sn-glycerol 3-phosphate + oleoyl-CoA → 1-oleyl-2-lyso-phosphatidate + coenzyme A ,
2.3.1.35: L-glutamate + N-acetyl-L-ornithine → N-acetyl-L-glutamate + L-ornithine ,
2.3.1.42: dihydroxyacetone phosphate + oleoyl-CoA → 1-oleoyl-2-lyso-glycerone phosphate + coenzyme A ,
2.3.1.47: pimeloyl-CoA + L-alanine + H+ → CO2 + 8-amino-7-oxononanoate + coenzyme A ,
2.3.1.47: a pimeloyl-[acp] + L-alanine + H+ = 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein] ,
2.3.1.51: 1-oleyl-2-lyso-phosphatidate + oleoyl-CoA → 1-18:1-2-18:1-phosphatidate + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.54: formate + acetyl-CoA ← pyruvate + coenzyme A ,
2.3.1.157: D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ ,
2.3.3.13: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+ ,
2.3.3.16: oxaloacetate + acetyl-CoA + H2O → citrate + coenzyme A + H+ ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = (1,4-α-D-glucosyl)(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a linear malto-oligosaccharide [(glucose)n] + phosphate = α-D-glucose 1-phosphate + a linear malto-oligosaccharide [(glucose)n-1] ,
2.4.1.1: maltotetraose + phosphate → maltotriose + α-D-glucose 1-phosphate ,
2.4.1.1: maltopentaose + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: maltohexaose + phosphate = maltopentaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltoheptaose + phosphate = maltohexaose + α-D-glucose 1-phosphate ,
2.4.1.1: SHG-glucosyln+1 + phosphate = SHG-glucosyln + α-D-glucose 1-phosphate ,
2.4.1.1: [(1→4)-α-D-glucosyl]n + phosphate = [(1→4)-α-D-glucosyl](n-1) + α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin = (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.12: UDP-α-D-glucose + cellulose(n) = cellulose(n+1) + UDP ,
2.4.1.13: UDP-α-D-glucose + β-D-fructofuranose ← sucrose + UDP + H+ ,
2.4.1.14: UDP-α-D-glucose + β-D-fructofuranose 6-phosphate → sucrose 6F-phosphate + UDP + H+ ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.18: a glucosylated glycogenin = a glycogen ,
2.4.1.18: n α-amylose = n amylopectin + n H2O ,
2.4.1.18: n a 1,4-α-D-glucan = a (1,6)-α-D-glucosyl-(1,4)-α-glucan highly branched + n H2O ,
2.4.1.18: a 1,4-α-D-glucan → a glycogen ,
2.4.1.21: ADP-α-D-glucose + (1,4-α-D-glucosyl)(n) → ADP + (1,4-α-D-glucosyl)(n+1) ,
2.4.1.25: maltotetraose + D-glucopyranose ← maltotriose + maltose ,
2.4.1.25: a maltodextrin(n+1) + α-D-glucose = a maltodextrin(n) + maltose ,
2.4.1.25: a glucan + D-glucopyranose = a glucan + maltotriose ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.25: maltopentaose + D-glucopyranose = maltotetraose + maltose ,
2.4.1.25: maltohexaose + β-D-glucose = maltopentaose + maltose ,
2.4.1.25: SHG-glucosyln+1 + β-D-glucose = SHG-glucosyln + maltose ,
2.4.1.25: a long-linear glucan + α-D-glucose = a short glucan + a short glucan ,
2.4.1.29: cellulose(n) + GDP-α-D-glucose = GDP + (1,4-β-D-glucosyl)(n+1) ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine]n-diphosphoundecaprenol + undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → di-trans,octa-cis-undecaprenyl diphosphate + [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine](n+1)-diphosphoundecaprenol ,
2.4.1.129: 2 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → a peptidoglycan dimer (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-pentapeptide]n-diphosphoundecaprenol + a lipid II → [GlcNAc-(1->4)-MurNAc-pentapeptide](n+1)-diphosphoundecaprenol + di-trans,octa-cis-undecaprenyl diphosphate ,
2.4.1.182: 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+ ,
2.4.1.227: decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UDP-N-acetyl-α-D-glucosamine → decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) + UDP + H+ ,
2.4.1.227: undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-α-D-glucosamine → undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+ ,
2.4.1.-: 2 decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) → a peptidoglycan dimer (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
2.4.2.1: inosine + phosphate → hypoxanthine + α-D-ribose-1-phosphate ,
2.4.2.1: a purine ribonucleoside + phosphate = a purine base + α-D-ribose-1-phosphate ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: adenosine + phosphate ↔ adenine + α-D-ribose-1-phosphate ,
2.4.2.1: 2'-deoxyadenosine + phosphate → adenine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 5'-deoxy-5'-chloroadenosine + phosphate = 5-chloro-5-deoxyribose 1-phosphate + adenine ,
2.4.2.1: 5'-deoxy-5'-fluoroadenosine + phosphate = adenine + 5-fluoro-5-deoxy-D-ribose 1-phosphate ,
2.4.2.1: a purine 2'-deoxyribonucleoside + phosphate = a purine base + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: a purine ribonucleoside + arsenate = a purine base + ribose-1-arsenate ,
2.4.2.7: AMP + diphosphate ← adenine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← hypoxanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.9: UMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate → guanine + α-D-ribose-1-phosphate ,
2.4.2.17: 1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ← ATP + 5-phospho-α-D-ribose 1-diphosphate + H+ ,
2.4.2.18: N-(5-phosphoribosyl)-anthranilate + diphosphate ← anthranilate + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.22: XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.-: phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+ ,
2.5.1.3: 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.3: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.3: 4-methyl-5-(2-phosphonooxyethyl)thiazole + 4-amino-2-methyl-5-diphosphomethylpyrimidine + H+ → thiamin phosphate + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.7: UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate → UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate ,
2.5.1.9: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin ,
2.5.1.15: 4-aminobenzoate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate → 7,8-dihydropteroate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.19: shikimate 3-phosphate + phosphoenolpyruvate → 5-enolpyruvyl-shikimate 3-phosphate + phosphate ,
2.5.1.29: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.39: all-trans-octaprenyl diphosphate + 4-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.54: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate ,
2.5.1.55: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.72: α-iminosuccinate + dihydroxyacetone phosphate → quinolinate + phosphate + 2 H2O ,
2.5.1.78: 5-amino-6-(D-ribitylamino)uracil + 1-deoxy-L-glycero-tetrulose 4-phosphate → 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + H+ + 2 H2O ,
2.5.1.105: 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = 7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphate + 2 H+ ,
2.6.1.1: L-aspartate + 2-oxoglutarate = L-glutamate + oxaloacetate ,
2.6.1.1: L-cysteate + 2-oxoglutarate = 3-sulfopyruvate + L-glutamate ,
2.6.1.1: L-phenylalanine + 2-oxoglutarate ↔ 2-oxo-3-phenylpropanoate + L-glutamate ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ L-glutamate + oxaloacetate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate ← L-glutamate + 4-methyl-2-oxopentanoate ,
2.6.1.9: imidazole acetol-phosphate + L-glutamate → L-histidinol-phosphate + 2-oxoglutarate ,
2.6.1.11: N-acetyl-L-ornithine + 2-oxoglutarate ← L-glutamate + N-acetyl-L-glutamate 5-semialdehyde ,
2.6.1.11: an [L-2-aminoadipate carrier protein]-L-ornithine + 2-oxoglutarate ↔ L-glutamate + an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.42: L-valine + 2-oxoglutarate ↔ L-glutamate + 3-methyl-2-oxobutanoate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate ← L-glutamate + (S)-3-methyl-2-oxopentanoate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← L-glutamate + 3-phospho-hydroxypyruvate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate → 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.57: L-tyrosine + 2-oxoglutarate ← 4-hydroxyphenylpyruvate + L-glutamate ,
2.6.1.62: S-adenosyl-L-methionine + 8-amino-7-oxononanoate ↔ S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminopelargonate ,
2.6.1.66: pyruvate + L-valine → L-alanine + 3-methyl-2-oxobutanoate ,
2.6.1.85: chorismate + L-glutamine → 4-amino-4-deoxychorismate + L-glutamate ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.99.2: 1-deoxy-D-xylulose 5-phosphate + 3-amino-1-hydroxyacetone 1-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.4: β-D-fructofuranose + ATP → β-D-fructofuranose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate = ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → phosphoadenosine-5'-phosphosulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → D-4'-phosphopantothenate + ADP + H+ ,
2.7.1.39: L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ ,
2.7.1.40: pyruvate + ATP ↔ phosphoenolpyruvate + ADP + H+ ,
2.7.1.49: ATP + hydroxymethylpyrimidine → ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine + H+ ,
2.7.1.50: ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ ,
2.7.1.66: di-trans,octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+ ,
2.7.1.71: shikimate + ATP → shikimate 3-phosphate + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.130: lipid A disaccharide + ATP → lipid IVA + ADP + H+ ,
2.7.1.146: β-D-fructofuranose 6-phosphate + ADP ← fructose 1,6-bisphosphate + AMP + H+ ,
2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP → 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP + H+ ,
2.7.1.170: 1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ ,
2.7.2.1: ATP + acetate ← ADP + acetyl phosphate ,
2.7.2.2: ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.4: L-aspartate + ATP → L-aspartyl-4-phosphate + ADP ,
2.7.2.8: N-acetyl-L-glutamate + ATP → N-acetylglutamyl-phosphate + ADP ,
2.7.2.8: an [L-2-aminoadipate carrier protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + ADP ,
2.7.2.11: L-glutamate + ATP → L-glutamate 5-phosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.6: GDP + ADP = GTP + AMP ,
2.7.4.6: ATP + IDP = ITP + ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: ATP + dIDP = ADP + dITP ,
2.7.4.7: 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP → 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.12/2.7.4.13: ATP + dTMP → ADP + dTDP ,
2.7.4.13: dGMP + ATP → dGDP + ADP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.16: thiamin phosphate + ATP → thiamin diphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.5: GTP + ATP → pppGpp + AMP ,
2.7.6.5: ATP + GDP → AMP + ppGpp ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.4: selenate + ATP + 2 H+ → adenosine 5'-phosphoselenate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ ↔ UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.18: β-nicotinate D-ribonucleotide + ATP + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.24: α-D-glucose 1-phosphate + dTTP + H+ = dTDP-α-D-glucose + diphosphate ,
2.7.7.27: α-D-glucose 1-phosphate + ATP + H+ → ADP-α-D-glucose + diphosphate ,
2.7.7.38: 3-deoxy-D-manno-octulosonate + CTP = CMP-3-deoxy-D-manno-octulosonate + diphosphate ,
2.7.7.39: sn-glycerol 3-phosphate + CTP + H+ = CDP-glycerol + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.41: CTP + a 2,3,4-saturated L-phosphatidate + H+ → a CDP-2,3,4-saturated-diacylglycerol + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate → a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate + CTP + H+ → 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + diphosphate ,
2.7.7.63: (R)-lipoate + ATP + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate → undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine + UMP ,
2.7.8.-: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + trans,octacis-decaprenyl phosphate → decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UMP ,
2.7.9.2: pyruvate + ATP + H2O → phosphoenolpyruvate + AMP + phosphate + 2 H+ ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.8.1.1: thiosulfate + hydrogen cyanide → sulfite + thiocyanate + 2 H+ ,
2.8.1.1: a sulfurated [sulfur carrier] + hydrogen cyanide → an unsulfurated [sulfur carrier] + thiocyanate + 2 H+ ,
2.8.1.6: a sulfurated [sulfur carrier] + dethiobiotin + 2 S-adenosyl-L-methionine → an unsulfurated [sulfur carrier] + biotin + 2 5'-deoxyadenosine + 2 L-methionine ,
2.8.1.7: L-cystein desulfurase + L-cysteine → an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.-: N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine + a sulfurated [sulfur carrier] = 2-thio-N6-dimethylallyladenosine37 in tRNA + an unsulfurated [sulfur carrier] + L-methionine + 5'-deoxyadenosine ,
2.8.4.3: N6-dimethylallyladenosine37 in tRNA + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier] → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + an unsulfurated [sulfur carrier] + H+ ,
2.-.-.-: heptosyl-Kdo2-lipid A + ADP-L-glycero-β-D-manno-heptose = (heptosyl)2-Kdo2-lipid A + ADP + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.15: L-histidinol-phosphate + H2O → histidinol + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.24: sucrose 6F-phosphate + H2O → sucrose + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.7.2: ppGpp + H2O → GDP + diphosphate + H+ ,
3.1.7.2: pppGpp + H2O → GTP + diphosphate + H+ ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.21.2: a single stranded DNA + n H2O → n a 5'-phosphooligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.2.1: guanosine + H2O → D-ribofuranose + guanine ,
3.2.2.9: S-adenosyl-L-homocysteine + H2O → S-ribosyl-L-homocysteine + adenine ,
3.2.2.14: β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.4.11.18: a peptide with an N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.16.4: 2 a peptidoglycan dimer (meso-diaminopimelate containing) → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine ,
3.4.17.13: L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine ,
3.4.21.50: a protein + H2O → a peptide + a peptide ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.5.1.10: 10-formyl-tetrahydrofolate + H2O → formate + tetrahydrofolate + H+ ,
3.5.1.16: N-acetyl-L-ornithine + H2O → L-ornithine + acetate ,
3.5.1.18: N-succinyl-L,L-2,6-diaminopimelate + H2O = L,L-diaminopimelate + succinate ,
3.5.1.19: nicotinamide + H2O → ammonium + nicotinate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.28: N-acetylmuramoyl-L-alaninate + H2O = N-acetylmuramate + L-alanine ,
3.5.1.31: N-formyl-L-methionine + H2O = L-methionine + formate ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.42: β-nicotinamide D-ribonucleotide + H2O → ammonium + β-nicotinate D-ribonucleotide ,
3.5.1.59: N-carbamoylsarcosine + 2 H+ + H2O → ammonium + CO2 + sarcosine ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.108: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + H2O → UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine + acetate ,
3.5.1.-: pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
3.5.1.-: an [L-2-aminoadipate carrier protein]-L-ornithine + H2O → L-ornithine + a [LysW protein]-L-glutamate ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.6: a β-lactam + H2O = a substituted β-amino acid ,
3.5.2.14: N-methylhydantoin + ATP + 2 H2O → N-carbamoylsarcosine + ADP + phosphate + 2 H+ ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.9: 5,10-methenyltetrahydrofolate + H2O ↔ 10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.13: dCTP + H+ + H2O → ammonium + dUTP ,
3.5.4.13: CTP + H+ + H2O = UTP + ammonium ,
3.5.4.16: GTP + H2O = formate + 7,8-dihydroneopterin triphosphate + H+ ,
3.5.4.19: 1-(5-phospho-β-D-ribosyl)-AMP + H2O → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ,
3.5.4.21: creatinine + H+ + H2O → ammonium + N-methylhydantoin ,
3.5.4.25: GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+ ,
3.5.4.26: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ + H2O → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.11: (polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.22: NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ ,
3.6.1.31: 1-(5-phospho-β-D-ribosyl)-ATP + H2O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H+ ,
3.6.1.40: pppGpp + H2O → ppGpp + phosphate + H+ ,
3.6.1.41: 5',5'''-diadenosine tetraphosphate + H2O = 2 ADP + 2 H+ ,
3.6.1.54: UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.3.14: ATP + 4 H+[in] + H2O ↔ ADP + phosphate + 5 H+[out] ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.27: ATP + phosphate[periplasmic space] + H2O → ADP + 2 phosphate[cytosol] + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
4.1.1.11: L-aspartate + H+ = β-alanine + CO2 ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.20: meso-diaminopimelate + H+ = CO2 + L-lysine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.31: oxaloacetate + phosphate ← phosphoenolpyruvate + hydrogen carbonate ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → coproporphyrinogen III + 4 CO2 ,
4.1.1.48: 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O ,
4.1.1.49: oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.72: 3-methyl-2-oxobutanoate + H+ → isobutanal + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.8: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate → indole + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.17: L-fuculose 1-phosphate = L-lactaldehyde + dihydroxyacetone phosphate ,
4.1.2.-: DL-allothreonine = acetaldehyde + glycine ,
4.1.3.27: chorismate + L-glutamine → anthranilate + L-glutamate + pyruvate + H+ ,
4.1.3.34: (3S)-citryl-CoA → oxaloacetate + acetyl-CoA ,
4.1.3.38: 4-amino-4-deoxychorismate → 4-aminobenzoate + pyruvate + H+ ,
4.1.99.12: D-ribulose 5-phosphate → formate + 1-deoxy-L-glycero-tetrulose 4-phosphate + H+ ,
4.1.99.17: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + carbon monoxide + 3 H+ ,
4.1.99.19: L-tyrosine + S-adenosyl-L-methionine + an unknown reduced electron acceptor → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + an unknown oxidized electron acceptor + 2 H+ ,
4.2.1.1: hydrogen carbonate + H+ ← CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.3: citrate = D-threo-isocitrate ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylpentanoate → (S)-3-methyl-2-oxopentanoate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylbutanoate → 3-methyl-2-oxobutanoate + H2O ,
4.2.1.10: 3-dehydroquinate → 3-dehydroshikimate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.19: D-erythro-imidazole-glycerol-phosphate → imidazole acetol-phosphate + H2O ,
4.2.1.20: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O ,
4.2.1.24: 2 5-amino-levulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.33: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate ,
4.2.1.47: GDP-α-D-mannose = GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.51: prephenate + H+ = 2-oxo-3-phenylpropanoate + CO2 + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.104: cyanate + hydrogen carbonate + 3 H+ = ammonium + 2 CO2 ,
4.2.1.104: cyanate + hydrogen carbonate + H+ → carbamate + CO2 ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl phosphate + H2O ,
4.2.1.122: L-serine + indole → L-tryptophan + H2O ,
4.2.1.126: N-acetyl-β-muramate 6-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + (R)-lactate ,
4.2.1.-: 5-chloro-5-deoxy-D-ribonate = 5-chloro-4-hydroxy-2-oxopentanoate + H2O ,
4.2.3.1: O-phospho-L-homoserine + H2O → L-threonine + phosphate ,
4.2.3.4: 3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate ,
4.2.3.5: 5-enolpyruvyl-shikimate 3-phosphate → chorismate + phosphate ,
4.3.2.1: L-arginino-succinate → L-arginine + fumarate ,
4.3.2.1: canavaninosuccinate = L-canavanine + fumarate ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.3.7: pyruvate + L-aspartate-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ ,
4.4.1.21: S-ribosyl-L-homocysteine → L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.12: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol → 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + CMP ,
4.99.1.1: protoporphyrin IX + Fe2+ → protoheme IX + 2 H+ ,
4.99.1.4: sirohydrochlorin + Fe2+ → siroheme + 2 H+ ,
5.1.1.1: L-alanine → D-alanine ,
5.1.1.3: L-glutamate → D-glutamate ,
5.1.1.7: L,L-diaminopimelate = meso-diaminopimelate ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.20: ADP-D-glycero-β-D-manno-heptose = ADP-L-glycero-β-D-manno-heptose ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate → β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.16: 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide → phosphoribulosylformimino-AICAR-P ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.1.24: N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate ,
5.3.1.28: D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H+ ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.14: a trans2-decenoyl-[acp] → a cis3-decenoyl-[acp] ,
5.3.99.10: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate → 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate ,
5.4.2.5: α-D-glucose 1-phosphate = D-glucopyranose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.10: D-glucosamine 1-phosphate ← D-glucosamine 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.2.12: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.3.8: glutamate-1-semialdehyde → 5-amino-levulinate ,
5.4.99.5: chorismate → prephenate ,
5.4.99.18: N5-carboxyaminoimidazole ribonucleotide → 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: eicosapentaenoate + ATP + coenzyme A → eicosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.4: succinate + GTP + coenzyme A ↔ succinyl-CoA + GDP + phosphate ,
6.2.1.4: itaconate + GTP + coenzyme A → itaconyl-CoA + GDP + phosphate ,
6.2.1.5: succinate + ATP + coenzyme A ↔ succinyl-CoA + ADP + phosphate ,
6.2.1.14: pimelate + ATP + coenzyme A → pimeloyl-CoA + AMP + diphosphate ,
6.2.1.18: citrate + ATP + coenzyme A → (3S)-citryl-CoA + ADP + phosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.5: ammonium + ATP + nicotinate adenine dinucleotide → AMP + NAD+ + diphosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + AMP + diphosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + ADP + phosphate + H+ ,
6.3.2.4: 2 D-alanine + ATP → D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.8: L-alanine + UDP-N-α-D-acetylmuramate + ATP → UDP-N-acetylmuramoyl-L-alanine + ADP + phosphate + H+ ,
6.3.2.9: UDP-N-acetylmuramoyl-L-alanine + D-glutamate + ATP → UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + ADP + phosphate + H+ ,
6.3.2.10: UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + D-alanyl-D-alanine + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.12: L-glutamate + 7,8-dihydropteroate + ATP → ADP + 7,8-dihydrofolate + phosphate + H+ ,
6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: L-glutamate + a [LysW protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate + ADP + phosphate + H+ ,
6.3.2.-: UDP-N-α-D-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: ATP + 5-formyl-tetrahydrofolate → 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.3.3: CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+ ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: ATP + formate + tetrahydrofolate → ADP + 10-formyl-tetrahydrofolate + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.5: O-ureidohomoserine + L-aspartate + ATP → canavaninosuccinate + AMP + diphosphate + H+ ,
6.3.4.13: 5-phospho-β-D-ribosylamine + ATP + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.18: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + hydrogen carbonate → N5-carboxyaminoimidazole ribonucleotide + ADP + phosphate + 2 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + carbamoyl-phosphate + 2 ADP + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.4.1.1: pyruvate + hydrogen carbonate + ATP → oxaloacetate + ADP + phosphate + H+ ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.7: ATP + 2-oxoglutarate + CO2 + H2O → oxalosuccinate + ADP + phosphate + 2 H+ ,
6.5.1.1: (deoxynucleotides)(m) + ATP + (deoxynucleotides)n → AMP + (deoxynucleotides)(n+m) + diphosphate ,
6.5.1.2: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
cis-aconitate + H2O ↔ D-threo-isocitrate ,
citrate ↔ cis-aconitate + H2O ,
ATP + UTP + ammonium = ADP + CTP + phosphate + 2 H+ ,
(2S)-2-isopropylmalate → 2-isopropylmaleate + H2O ,
2-isopropylmaleate + H2O → (2R,3S)-3-isopropylmalate ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
carbamate + 2 H+ → ammonium + CO2 ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
S-adenosyl-L-methionine + precorrin-1 → S-adenosyl-L-homocysteine + precorrin-2 ,
S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+ ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
4 H+[in] → 4 H+[out] ,
dimethyl sulfoxide + NADH + H+ = dimethyl sulfide + NAD+ + H2O ,
a uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + H+ → 3-amino-1-hydroxyacetone 1-phosphate + CO2 ,
4-phospho-hydroxy-L-threonine + NAD+(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+ ,
histidinal + NAD+ + H2O → L-histidine + NADH + 2 H+ ,
histidinol + NAD+ → histidinal + NADH + H+ ,
2-oxoglutarate + coenzyme A + NAD+ → succinyl-CoA + CO2 + NADH ,
ribose-1-arsenate + dihydrolipoate + H+ = D-ribofuranose + arsenite + (R)-lipoate ,
deethylsimazine + H2O = N-ethylammeline + chloride + H+ ,
5 S0 + oxygen + 4 H2O → sulfite + thiosulfate + 2 hydrogen sulfide + 3 H+ ,
(2S)-2-isopropyl-3-oxosuccinate + H+ → 4-methyl-2-oxopentanoate + CO2 ,
(2R,3S)-3-isopropylmalate + NAD+ → (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ ,
nitrate[out] + 2 H+[out] + 2 e-[membrane] → nitrite[out] + H2O[out] ,
ammonium[out] → ammonium[in] ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with D,D cross-links (mycobacteria) + 4 D-alanine + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with L,D cross-links (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + 4 D-alanine + H+ ,
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate + H+ ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
formate + H+ → CO2 + H2 ,
n S0 + HS- → (sulfide)n+1 + H+ ,
glycine + tetrahydrofolate + NAD+ → ammonium + CO2 + 5,10-methylenetetrahydrofolate + NADH ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
an S-sulfanyl-[L-cysteine desulfurase] + a ThiI sulfur-carrier protein → L-cystein desulfurase + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
glycine + oxygen → 2-iminoacetate + hydrogen peroxide + H+ ,
selenodiglutathione + NADPH → glutathioselenol + glutathione + NADP+ ,
glutathioselenol + NADPH + 2 H+ → hydrogen selenide + glutathione + NADP+ ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ = 3-amino-4,7-dihydroxy-coumarin + a NovH peptidyl-carrier protein + NADPH + H+ ,
(S)-4,5-dihydroxypentan-2,3-dione → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
(S)-4,5-dihydroxypentan-2,3-dione → (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
ammonia + H+ ↔ ammonium ,
NADH + H2O → (S)-NADHX ,
NADH + H2O → (R)-NADHX ,
2-iminoacetate + H+ + H2O → glyoxylate + ammonium ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
glutathione + S0 → S-sulfanylglutathione ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
aldehydo-D-ribose ↔ D-ribofuranose ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
formaldehyde + tetrahydrofolate → 5,10-methylenetetrahydrofolate + H2O ,
(S)-2-acetolactate + an unknown oxidized electron acceptor + H+ → diacetyl + CO2 + an unknown reduced electron acceptor ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
sulfite + H+ ↔ bisulfite ,
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
aldehydo-D-ribose ↔ D-ribopyranose ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
Mg2+[periplasmic space] → Mg2+[cytosol]


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