Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Aquifex aeolicus VF5 Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: methionol + NAD+ = 3-methylthiopropanal + NADH + H+ ,
1.1.1.1: 2-phenylethanol + NAD+ = phenylacetaldehyde + NADH + H+ ,
1.1.1.1: 2-methylbutanol + NAD+ = 2-methylbutanal + NADH + H+ ,
1.1.1.1: 3-methylbutanol + NAD+ ↔ 3-methylbutanal + NADH + H+ ,
1.1.1.1: isobutanol + NAD+ ↔ isobutanal + NADH + H+ ,
1.1.1.1: indole-3-glycol + NAD+ = indole-3-glycol aldehyde + NADH + H+ ,
1.1.1.1: phytol + NAD+ = phytenal + NADH + H+ ,
1.1.1.1: 4-tyrosol + NAD+ = (4-hydroxyphenyl)acetaldehyde + NADH + H+ ,
1.1.1.1: n-propanol + NAD+ = propanal + NADH + H+ ,
1.1.1.1: a secondary alcohol + NAD+ = a ketone + NADH + H+ ,
1.1.1.1: 3-methoxy-4-hydroxyphenylglycol + NAD+ ↔ 3-methoxy-4-hydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 3,4-dihydroxyphenylglycol + NAD+ = 3,4-dihydroxyphenylglycolaldehyde + NADH + H+ ,
1.1.1.1: 5-hydroxytryptophol + NAD+ = 5-hydroxyindole acetaldehyde + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ = an aldehyde + NADH + H+ ,
1.1.1.3: L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+ ,
1.1.1.8: sn-glycerol 3-phosphate + NAD+ ← dihydroxyacetone phosphate + NADH + H+ ,
1.1.1.23: histidinol + 2 NAD+ + H2O = L-histidine + 2 NADH + 3 H+ ,
1.1.1.25: shikimate + NADP+ ← 3-dehydroshikimate + NADPH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.31: (S)-3-hydroxy-isobutanoate + NAD+ = (S)-methylmalonate-semialdehyde + NADH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/4.1.1.3: oxaloacetate + H+ = pyruvate + CO2 ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ → pyruvate + CO2 + NADH ,
1.1.1.40: (S)-malate + NADP+ → CO2 + pyruvate + NADPH ,
1.1.1.41: D-threo-isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH ,
1.1.1.42: D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.82: (S)-malate + NADP+ = oxaloacetate + NADPH + H+ ,
1.1.1.85: 3-ethylmalate + NAD+ = 2-oxovalerate + CO2 + NADH ,
1.1.1.85: (2R,3S)-3-isopropylmalate + NAD+ = 4-methyl-2-oxopentanoate + CO2 + NADH ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ ← (S)-2-acetolactate + NADPH + H+ ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+ ,
1.1.1.94: sn-glycerol 3-phosphate + NAD(P)+ ← dihydroxyacetone phosphate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ → 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.100: 3-oxo-docosapentaenoyl-CoA + NAD(P)H + H+ → 3-hydroxy-docosapentaenoyl-CoA + NAD(P)+ ,
1.1.1.101: 1-oleoyl-2-lyso-glycerone phosphate + NADPH + H+ → 1-oleyl-2-lyso-phosphatidate + NADP+ ,
1.1.1.169: (R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ ,
1.1.1.193: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+ ← 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ ,
1.1.1.202: 1,3-propanediol + NAD+ = 3-hydroxypropionaldehyde + NADH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.262: 4-phospho-hydroxy-L-threonine + NAD+ = 3-amino-1-hydroxyacetone 1-phosphate + CO2 + NADH ,
1.1.1.267: 2-C-methyl-D-erythritol 4-phosphate + NADP+ ← 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ ,
1.1.1.282: shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+ ,
1.1.1.290: erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ ,
1.1.1.299: (S)-malate + NAD(P)+ = oxaloacetate + NAD(P)H + H+ ,
1.1.1.343: D-gluconate 6-phosphate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH ,
1.1.1.351: D-gluconate 6-phosphate + NAD(P)+ → D-ribulose 5-phosphate + CO2 + NAD(P)H ,
1.1.1.-: 1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
1.1.1.-: D-threo-isocitrate + NAD+ ← oxalosuccinate + NADH + H+ ,
1.1.5.3: sn-glycerol 3-phosphate[in] + an electron-transfer-related quinone → dihydroxyacetone phosphate[in] + an electron-transfer-related quinol ,
1.1.5.4: (S)-malate + a quinone → oxaloacetate + a quinol ,
1.1.5.4: (S)-malate + a menaquinone = oxaloacetate + a menaquinol ,
1.1.5.5: ethanol + an ubiquinone = acetaldehyde + an ubiquinol ,
1.1.5.-: (R)-lactate[in] + an electron-transfer-related quinone → pyruvate[in] + an electron-transfer-related quinol ,
1.1.99.33: formate + an oxidized electron acceptor + H+ = CO2 + a reduced electron acceptor ,
1.2.1.2: formate + NAD+ → CO2 + NADH ,
1.2.1.3: 4-acetamidobutanal + NAD+ + H2O = 4-acetamidobutanoate + NADH + 2 H+ ,
1.2.1.3: acetaldehyde + NAD+ + H2O → acetate + NADH + 2 H+ ,
1.2.1.3: octanal + NAD+ + H2O = octanoate + NADH + 2 H+ ,
1.2.1.3: an aldehyde + NAD+ + H2O = a carboxylate + NADH + 2 H+ ,
1.2.1.3: a 2-methyl branched 2,3,4-saturated fatty aldehyde + NAD+ + H2O = a 2-methyl branched 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty aldehyde + NAD+ + H2O = an odd numbered straight chain 2,3,4-saturated fatty acid + NADH + 2 H+ ,
1.2.1.3: phytenal + NAD+ + H2O = phytenate + NADH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O = a carboxylate + NADPH + 2 H+ ,
1.2.1.4: acetaldehyde + NADP+ + H2O = acetate + NADPH + 2 H+ ,
1.2.1.7: benzaldehyde + NADP+ + H2O = benzoate + NADPH + 2 H+ ,
1.2.1.9: D-glyceraldehyde 3-phosphate + NADP+ + H2O = 3-phospho-D-glycerate + NADPH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ ↔ acetyl-CoA + NADH + H+ ,
1.2.1.11: L-aspartate-semialdehyde + NADP+ + phosphate ← L-aspartyl-4-phosphate + NADPH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.13: D-glyceraldehyde 3-phosphate + NADP+ + phosphate ← 1,3-bisphospho-D-glycerate + NADPH + H+ ,
1.2.1.22: L-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + 2 H+ ,
1.2.1.28: benzaldehyde + NAD+ + H2O = benzoate + NADH + 2 H+ ,
1.2.1.38: an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde + NADP+ + phosphate ← an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.38: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate ← N-acetylglutamyl-phosphate + NADPH + H+ ,
1.2.1.41: L-glutamate-5-semialdehyde + NADP+ + phosphate ← L-glutamate 5-phosphate + NADPH + H+ ,
1.2.1.43: formate + NADP+ ← CO2 + NADPH ,
1.2.1.59: D-glyceraldehyde 3-phosphate + NAD(P)+ + phosphate = 1,3-bisphospho-D-glycerate + NAD(P)H + H+ ,
1.2.1.65: salicylaldehyde + NAD+ + H2O = salicylate + NADH + 2 H+ ,
1.2.1.69: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.72: D-erythrose 4-phosphate + NAD+ + H2O → erythronate-4-phosphate + NADH + 2 H+ ,
1.2.1.-: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
1.2.1.-: apo-4'-lycopenal + NAD(P)+ + H2O = apo-4'-lycopenoate + NADPH + H+ ,
1.3.1.12: prephenate + NAD+ → 4-hydroxyphenylpyruvate + CO2 + NADH ,
1.3.1.13: prephenate + NADP+ = 4-hydroxyphenylpyruvate + CO2 + NADPH ,
1.3.1.14: (S)-dihydroorotate + NAD+ = orotate + NADH + H+ ,
1.3.1.76: precorrin-2 + NAD+ → sirohydrochlorin + NADH + 2 H+ ,
1.3.1.98: UDP-N-α-D-acetylmuramate + NADP+ ← UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.5.1: succinate[in] + an electron-transfer-related quinone → fumarate[in] + an electron-transfer-related quinol ,
1.3.5.1: succinate[in] + an ubiquinone → fumarate[in] + an ubiquinol ,
1.3.5.2: (S)-dihydroorotate[in] + an ubiquinone → orotate[in] + an ubiquinol ,
1.3.5.3: protoporphyrinogen IX + 3 a menaquinone → protoporphyrin IX + 3 a menaquinol ,
1.3.5.4: fumarate[in] + a rhodoquinol → succinate[in] + a rhodoquinone ,
1.3.5.4: fumarate[in] + a menaquinol → succinate[in] + a menaquinone ,
1.3.99.22: coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine ,
1.4.1.4: L-glutamate + NADP+ + H2O ← ammonium + 2-oxoglutarate + NADPH + H+ ,
1.4.1.13: 2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+ ,
1.4.1.14: 2 L-glutamate + NAD+ ← L-glutamine + 2-oxoglutarate + NADH + H+ ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.16: L-aspartate + oxygen → α-iminosuccinate + hydrogen peroxide + H+ ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: tetrahydrofolate + NADP+ ← 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: 5,10-methylenetetrahydrofolate + NADP+ ↔ 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.15: 5,10-methylenetetrahydrofolate + NAD+ → 5,10-methenyltetrahydrofolate + NADH ,
1.5.1.20: 5-methyl-tetrahydrofolate + NAD+ ← 5,10-methylenetetrahydrofolate + NADH + H+ ,
1.5.1.-: tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ ,
1.5.3.1: sarcosine + oxygen + H2O → glycine + formaldehyde + hydrogen peroxide ,
1.5.8.3: sarcosine + an oxidized electron-transfer flavoprotein + H2O → glycine + formaldehyde + a reduced electron-transfer flavoprotein ,
1.5.99.-: L-aspartate + fumarate = α-iminosuccinate + succinate + H+ ,
1.6.5.3: NADH[in] + an ubiquinone + 5 H+[in] ↔ NAD+[in] + an ubiquinol + 4 H+[out] ,
1.6.5.9: NADH[in] + an ubiquinone + H+[in] → NAD+[in] + an ubiquinol ,
1.6.99.3: NADH + an oxidized electron acceptor + H+ = NAD+ + a reduced electron acceptor ,
1.7.1.1: nitrite + NAD+ + H2O = nitrate + NADH + H+ ,
1.7.1.2: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+ ,
1.7.1.3: nitrite + NADP+ + H2O ← nitrate + NADPH + H+ ,
1.7.1.4: ammonium + 3 NAD(P)+ + 2 H2O ← nitrite + 3 NAD(P)H + 5 H+ ,
1.7.1.13: preQ1 + 2 NADP+ ← preQ0 + 2 NADPH + 3 H+ ,
1.7.5.1: nitrate[in] + a menaquinol + 2 H+[in] → nitrite[in] + a menaquinone + H2O[in] + 2 H+[out] ,
1.7.99.4: nitrate[out] + an ubiquinol → nitrite[out] + an ubiquinone + H2O[out] ,
1.7.99.4: nitrite + an oxidized electron acceptor + H2O = nitrate + a reduced electron acceptor ,
1.8.1.19: (sulfide)n + hydrogen sulfide + NADP+ = (sulfide)n+1 + NADPH + H+ ,
1.8.1.-: an alcohol + NAD+ + H2O ← an organic hydroperoxide + NADH + H+ ,
1.8.4.9: selenite + AMP + glutathione disulfide + 3 H+ ← adenosine 5'-phosphoselenate + 2 glutathione ,
1.8.5.3: dimethyl sulfoxide[out] + a menaquinol → dimethyl sulfide[out] + a menaquinone + H2O[out] ,
1.8.5.4: hydrogen sulfide + an electron-transfer-related quinone → intracellular S0 + an electron-transfer-related quinol ,
1.8.98.1: methanophenazine + coenzyme B + coenzyme M = CoB-CoM heterodisulfide + dihydromethanophenazine ,
1.10.3.11: 2 an ubiquinol + oxygen[in] → 2 an ubiquinone + 2 H2O[in] ,
1.10.3.14: 2 an ubiquinol + 4 H+[in] + oxygen[in] → 2 an ubiquinone + 4 H+[out] + 2 H2O[in] ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.12.1.2: NAD+ + H2 ↔ NADH + H+ ,
1.12.1.3: NADP+ + H2 ↔ NADPH + H+ ,
1.12.98.4: (sulfide)n + H2 → hydrogen sulfide + (sulfide)n-1 ,
1.12.99.6: a menaquinone + 2 H+[in] + H2[out] → a menaquinol + 2 H+[out] ,
1.12.99.6: an oxidized electron acceptor + H2 ↔ a reduced electron acceptor ,
1.13.11.54: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + oxygen → 2-oxo-4-methylthiobutanoate + formate + H+ ,
1.13.11.55: 4 S0 + 4 H2O + oxygen → 2 hydrogen sulfide + 2 sulfite + 4 H+ ,
1.14.13.-: β-oxo-L-tyrosine-S-[NovH protein] + NADPH + oxygen + H+ → 2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ + H2O ,
1.14.16.1: tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.17.1.2: dimethylallyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.2: isopentenyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.7.1: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + 2 an oxidized ferredoxin + H2O = 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + 2 a reduced ferredoxin + H+ ,
2.1.1.13: L-homocysteine + 5-methyl-tetrahydrofolate → L-methionine + tetrahydrofolate ,
2.1.1.14: L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate → L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.14: seleno-L-homocysteine + 5-methyltetrahydropteroyl tri-L-glutamate + H+ = seleno-L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.19: trimethyl sulfonium + tetrahydrofolate ← dimethyl sulfide + 5-methyl-tetrahydrofolate + H+ ,
2.1.1.45: dUMP + 5,10-methylenetetrahydrofolate → dTMP + 7,8-dihydrofolate ,
2.1.1.79: a phospholipid olefinic fatty acid + S-adenosyl-L-methionine → a phospholipid cyclopropane fatty acid + S-adenosyl-L-homocysteine + H+ ,
2.1.1.107: 2 S-adenosyl-L-methionine + uroporphyrinogen-III → 2 S-adenosyl-L-homocysteine + precorrin-2 + H+ ,
2.1.1.148: dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ → dTMP + tetrahydrofolate + NADP+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor ,
2.1.1.-: 2-thio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.2.1: L-serine + tetrahydrofolate ↔ glycine + 5,10-methylenetetrahydrofolate + H2O ,
2.1.2.2: N1-(5-phospho-β-D-ribosyl)glycinamide + 10-formyl-tetrahydrofolate → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + tetrahydrofolate + H+ ,
2.1.2.3: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 10-formyl-tetrahydrofolate → 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide + tetrahydrofolate ,
2.1.2.11: 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydrofolate + H2O → 2-dehydropantoate + tetrahydrofolate ,
2.1.2.-: N1-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + ADP + phosphate + H+ ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate = L-citrulline + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate ↔ L-citrulline + phosphate + H+ ,
2.1.3.-: L-canaline + carbamoyl-phosphate = O-ureidohomoserine + phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate → β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ← D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate → β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.2.1.6: pyruvate + 2-oxobutanoate + H+ → (S)-2-aceto-2-hydroxybutanoate + CO2 ,
2.2.1.6: 2 pyruvate + H+ → (S)-2-acetolactate + CO2 ,
2.2.1.7: pyruvate + D-glyceraldehyde 3-phosphate + H+ → 1-deoxy-D-xylulose 5-phosphate + CO2 ,
2.3.1.1: L-glutamate + acetyl-CoA → N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.1: L-methionine + acetyl-CoA = N-α-acetyl-L-methionine + coenzyme A + H+ ,
2.3.1.8: acetyl-CoA + phosphate → acetyl phosphate + coenzyme A ,
2.3.1.15: sn-glycerol 3-phosphate + oleoyl-CoA → 1-oleyl-2-lyso-phosphatidate + coenzyme A ,
2.3.1.15: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = 1-C16:0-α,ω-dicaboxyl-2-lysophosphatidate + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.35: L-glutamate + N-acetyl-L-ornithine → N-acetyl-L-glutamate + L-ornithine ,
2.3.1.42: dihydroxyacetone phosphate + oleoyl-CoA → 1-oleoyl-2-lyso-glycerone phosphate + coenzyme A ,
2.3.1.47: a pimeloyl-[acp] + L-alanine + H+ = 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein] ,
2.3.1.47: pimeloyl-CoA + L-alanine + H+ → CO2 + 8-amino-7-oxononanoate + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.51: 1-oleyl-2-lyso-phosphatidate + oleoyl-CoA → 1-18:1-2-18:1-phosphatidate + coenzyme A ,
2.3.1.54: formate + acetyl-CoA ← pyruvate + coenzyme A ,
2.3.1.157: D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ ,
2.3.3.13: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+ ,
2.3.3.16: oxaloacetate + acetyl-CoA + H2O → citrate + coenzyme A + H+ ,
2.4.1.1: [(1→4)-α-D-glucosyl]n + phosphate = [(1→4)-α-D-glucosyl](n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: SHG-glucosyln+1 + phosphate = SHG-glucosyln + α-D-glucose 1-phosphate ,
2.4.1.1: maltoheptaose + phosphate = maltohexaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltohexaose + phosphate = maltopentaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltopentaose + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: maltotetraose + phosphate → maltotriose + α-D-glucose 1-phosphate ,
2.4.1.1: a linear malto-oligosaccharide [(glucose)n] + phosphate = α-D-glucose 1-phosphate + a linear malto-oligosaccharide [(glucose)n-1] ,
2.4.1.1: a maltodextrin(n) + phosphate = a maltodextrin(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: a debranched limit dextrin + n phosphate → n α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate = (1,4-α-D-glucosyl)(n-1) + α-D-glucose 1-phosphate ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.11: UDP-α-D-glucose + (1,4-α-D-glucosyl)(n) glycogenin = (1,4-α-D-glucosyl)(n+1) glycogenin + UDP ,
2.4.1.12: UDP-α-D-glucose + cellulose(n) = cellulose(n+1) + UDP ,
2.4.1.13: UDP-α-D-glucose + β-D-fructofuranose ← sucrose + UDP + H+ ,
2.4.1.14: UDP-α-D-glucose + β-D-fructofuranose 6-phosphate → sucrose 6F-phosphate + UDP + H+ ,
2.4.1.18: a 1,4-α-D-glucan → a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = a (1,6)-α-D-glucosyl-(1,4)-α-glucan highly branched + n H2O ,
2.4.1.18: n α-amylose = n amylopectin + n H2O ,
2.4.1.18: a glucosylated glycogenin = a glycogen ,
2.4.1.18: n a 1,4-α-D-glucan = n starch + n H2O ,
2.4.1.21: ADP-α-D-glucose + (1,4-α-D-glucosyl)(n) → ADP + (1,4-α-D-glucosyl)(n+1) ,
2.4.1.25: a long-linear glucan + α-D-glucose = a short glucan + a short glucan ,
2.4.1.25: SHG-glucosyln+1 + β-D-glucose = SHG-glucosyln + maltose ,
2.4.1.25: maltohexaose + β-D-glucose = maltopentaose + maltose ,
2.4.1.25: maltopentaose + D-glucopyranose = maltotetraose + maltose ,
2.4.1.25: a limit dextrin → a limit dextrin with short branches ,
2.4.1.25: a glucan + D-glucopyranose = a glucan + maltotriose ,
2.4.1.25: a maltodextrin(n+1) + α-D-glucose = a maltodextrin(n) + maltose ,
2.4.1.25: maltotetraose + D-glucopyranose ← maltotriose + maltose ,
2.4.1.29: cellulose(n) + GDP-α-D-glucose = GDP + (1,4-β-D-glucosyl)(n+1) ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-pentapeptide]n-diphosphoundecaprenol + a lipid II → [GlcNAc-(1->4)-MurNAc-pentapeptide](n+1)-diphosphoundecaprenol + di-trans,octa-cis-undecaprenyl diphosphate ,
2.4.1.129: 2 undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → a peptidoglycan dimer (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine]n-diphosphoundecaprenol + undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → di-trans,octa-cis-undecaprenyl diphosphate + [GlcNAc-(1->4)-MurNAc-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine](n+1)-diphosphoundecaprenol ,
2.4.1.182: 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+ ,
2.4.1.227: undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-α-D-glucosamine → undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+ ,
2.4.1.227: decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UDP-N-acetyl-α-D-glucosamine → decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) + UDP + H+ ,
2.4.1.-: 2 decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide) → a peptidoglycan dimer (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
2.4.2.1: a purine ribonucleoside + arsenate = a purine base + ribose-1-arsenate ,
2.4.2.1: a purine 2'-deoxyribonucleoside + phosphate = a purine base + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 5'-deoxy-5'-fluoroadenosine + phosphate = adenine + 5-fluoro-5-deoxy-D-ribose 1-phosphate ,
2.4.2.1: 5'-deoxy-5'-chloroadenosine + phosphate = 5-chloro-5-deoxyribose 1-phosphate + adenine ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyadenosine + phosphate → adenine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: adenosine + phosphate ↔ adenine + α-D-ribose-1-phosphate ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: a purine ribonucleoside + phosphate = a purine base + α-D-ribose-1-phosphate ,
2.4.2.1: inosine + phosphate → hypoxanthine + α-D-ribose-1-phosphate ,
2.4.2.7: AMP + diphosphate ← adenine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← hypoxanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.9: UMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate → guanine + α-D-ribose-1-phosphate ,
2.4.2.17: 1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ← ATP + 5-phospho-α-D-ribose 1-diphosphate + H+ ,
2.4.2.18: N-(5-phosphoribosyl)-anthranilate + diphosphate ← anthranilate + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.22: XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.-: phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+ ,
2.5.1.3: 4-methyl-5-(2-phosphonooxyethyl)thiazole + 4-amino-2-methyl-5-diphosphomethylpyrimidine + H+ → thiamin phosphate + diphosphate ,
2.5.1.3: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.3: 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.7: UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate → UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate ,
2.5.1.9: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin ,
2.5.1.15: 4-aminobenzoate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate → 7,8-dihydropteroate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.19: shikimate 3-phosphate + phosphoenolpyruvate → 5-enolpyruvyl-shikimate 3-phosphate + phosphate ,
2.5.1.29: (2E,6E)-farnesyl diphosphate + isopentenyl diphosphate → geranylgeranyl diphosphate + diphosphate ,
2.5.1.39: all-trans-octaprenyl diphosphate + 4-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.54: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate ,
2.5.1.55: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O = 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.72: α-iminosuccinate + dihydroxyacetone phosphate → quinolinate + phosphate + 2 H2O ,
2.5.1.78: 5-amino-6-(D-ribitylamino)uracil + 1-deoxy-L-glycero-tetrulose 4-phosphate → 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + H+ + 2 H2O ,
2.5.1.105: 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = 7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphate + 2 H+ ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ L-glutamate + oxaloacetate ,
2.6.1.1: L-phenylalanine + 2-oxoglutarate ↔ 2-oxo-3-phenylpropanoate + L-glutamate ,
2.6.1.1: L-cysteate + 2-oxoglutarate = 3-sulfopyruvate + L-glutamate ,
2.6.1.1: L-aspartate + 2-oxoglutarate = L-glutamate + oxaloacetate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate ← L-glutamate + 4-methyl-2-oxopentanoate ,
2.6.1.9: imidazole acetol-phosphate + L-glutamate → L-histidinol-phosphate + 2-oxoglutarate ,
2.6.1.11: an [L-2-aminoadipate carrier protein]-L-ornithine + 2-oxoglutarate ↔ L-glutamate + an [L-2-aminoadipate carrier protein]-L-glutamate 5-semialdehyde ,
2.6.1.11: N-acetyl-L-ornithine + 2-oxoglutarate ← L-glutamate + N-acetyl-L-glutamate 5-semialdehyde ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate ← L-glutamate + (S)-3-methyl-2-oxopentanoate ,
2.6.1.42: L-valine + 2-oxoglutarate ↔ L-glutamate + 3-methyl-2-oxobutanoate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate → 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ← L-glutamate + 3-phospho-hydroxypyruvate ,
2.6.1.57: L-tyrosine + 2-oxoglutarate ← 4-hydroxyphenylpyruvate + L-glutamate ,
2.6.1.62: S-adenosyl-L-methionine + 8-amino-7-oxononanoate ↔ S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminopelargonate ,
2.6.1.66: pyruvate + L-valine → L-alanine + 3-methyl-2-oxobutanoate ,
2.6.1.85: chorismate + L-glutamine → 4-amino-4-deoxychorismate + L-glutamate ,
2.6.1.88: L-methionine + a 2-oxo carboxylate ← 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.99.2: 1-deoxy-D-xylulose 5-phosphate + 3-amino-1-hydroxyacetone 1-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.4: β-D-fructofuranose + ATP → β-D-fructofuranose 6-phosphate + ADP + H+ ,
2.7.1.11: ATP + β-D-fructofuranose 6-phosphate = ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP → phosphoadenosine-5'-phosphosulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → D-4'-phosphopantothenate + ADP + H+ ,
2.7.1.39: L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ ,
2.7.1.40: pyruvate + ATP ↔ phosphoenolpyruvate + ADP + H+ ,
2.7.1.49: ATP + hydroxymethylpyrimidine → ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine + H+ ,
2.7.1.50: ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ ,
2.7.1.66: di-trans,octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+ ,
2.7.1.71: shikimate + ATP → shikimate 3-phosphate + ADP + H+ ,
2.7.1.74/2.7.1.76/2.7.1.145: 2'-deoxyadenosine + ATP → dAMP + ADP + H+ ,
2.7.1.74/2.7.1.113/2.7.1.145: 2'-deoxyguanosine + ATP → dGMP + ADP + H+ ,
2.7.1.130: lipid A disaccharide + ATP → lipid IVA + ADP + H+ ,
2.7.1.146: β-D-fructofuranose 6-phosphate + ADP ← fructose 1,6-bisphosphate + AMP + H+ ,
2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP → 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP + H+ ,
2.7.1.170: 1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ ,
2.7.2.1: ATP + acetate ← ADP + acetyl phosphate ,
2.7.2.2: ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.4: L-aspartate + ATP → L-aspartyl-4-phosphate + ADP ,
2.7.2.8: an [L-2-aminoadipate carrier protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate 5-phosphate + ADP ,
2.7.2.8: N-acetyl-L-glutamate + ATP → N-acetylglutamyl-phosphate + ADP ,
2.7.2.11: L-glutamate + ATP → L-glutamate 5-phosphate + ADP ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.6: ATP + dIDP = ADP + dITP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: ATP + IDP = ITP + ADP ,
2.7.4.6: GDP + ADP = GTP + AMP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP = a nucleoside triphosphate + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.7: 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP → 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.12/2.7.4.13: ATP + dTMP → ADP + dTDP ,
2.7.4.13: ATP + dAMP → ADP + dADP ,
2.7.4.13: dGMP + ATP → dGDP + ADP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.16: thiamin phosphate + ATP → thiamin diphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.6.1: D-ribose 5-phosphate + ATP = 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.5: ATP + GDP → AMP + ppGpp ,
2.7.6.5: GTP + ATP → pppGpp + AMP ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.4: selenate + ATP + 2 H+ → adenosine 5'-phosphoselenate + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ ↔ UDP-α-D-glucose + diphosphate ,
2.7.7.10: α-D-galactose 1-phosphate + UTP + H+ = UDP-α-D-galactose + diphosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.18: β-nicotinate D-ribonucleotide + ATP + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.24: α-D-glucose 1-phosphate + dTTP + H+ = dTDP-α-D-glucose + diphosphate ,
2.7.7.27: α-D-glucose 1-phosphate + ATP + H+ → ADP-α-D-glucose + diphosphate ,
2.7.7.38: 3-deoxy-D-manno-octulosonate + CTP = CMP-3-deoxy-D-manno-octulosonate + diphosphate ,
2.7.7.39: sn-glycerol 3-phosphate + CTP + H+ = CDP-glycerol + diphosphate ,
2.7.7.41: CTP + a 2,3,4-saturated L-phosphatidate + H+ → a CDP-2,3,4-saturated-diacylglycerol + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate → a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate + CTP + H+ → 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate = undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine + UMP ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate → undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP ,
2.7.8.-: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + trans,octacis-decaprenyl phosphate → decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide + UMP ,
2.7.9.2: pyruvate + ATP + H2O → phosphoenolpyruvate + AMP + phosphate + 2 H+ ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.8.1.1: a sulfurated [sulfur carrier] + hydrogen cyanide → an unsulfurated [sulfur carrier] + thiocyanate + 2 H+ ,
2.8.1.1: thiosulfate + hydrogen cyanide → sulfite + thiocyanate + 2 H+ ,
2.8.1.6: a sulfurated [sulfur carrier] + dethiobiotin + 2 S-adenosyl-L-methionine → an unsulfurated [sulfur carrier] + biotin + 2 5'-deoxyadenosine + 2 L-methionine ,
2.8.1.7: an [L-cysteine desulfurase] + L-cysteine → an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.-: N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine + a sulfurated [sulfur carrier] = 2-thio-N6-dimethylallyladenosine37 in tRNA + an unsulfurated [sulfur carrier] + L-methionine + 5'-deoxyadenosine ,
2.8.4.3: N6-dimethylallyladenosine37 in tRNA + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier] → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + an unsulfurated [sulfur carrier] + H+ ,
2.-.-.-: heptosyl-Kdo2-lipid A + ADP-L-glycero-β-D-manno-heptose = (heptosyl)2-Kdo2-lipid A + ADP + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.5: XMP + H2O → xanthosine + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.13: 2,3-diphospho-D-glycerate + H2O → 3-phospho-D-glycerate + phosphate ,
3.1.3.15: L-histidinol-phosphate + H2O → histidinol + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.24: sucrose 6F-phosphate + H2O → sucrose + phosphate ,
3.1.3.25: 1D-myo-inositol 2-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 6-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 5-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 4-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: a myo-inositol monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 3-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.87: 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O → 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate ,
3.1.7.2: pppGpp + H2O → GTP + diphosphate + H+ ,
3.1.7.2: ppGpp + H2O → GDP + diphosphate + H+ ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.21.2: a single stranded DNA + n H2O → n a 5'-phosphooligonucleotide ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.33: a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose ,
3.2.1.33: a limit dextrin + H2O → maltotetraose + a debranched limit dextrin ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.2.1: guanosine + H2O → D-ribofuranose + guanine ,
3.2.2.9: S-adenosyl-L-homocysteine + H2O → S-ribosyl-L-homocysteine + adenine ,
3.2.2.14: β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ ,
3.3.1.1: S-adenosyl-L-homocysteine + H2O → L-homocysteine + adenosine ,
3.4.11.18: a peptide with N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.16.4: 2 a peptidoglycan dimer (meso-diaminopimelate containing) → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine ,
3.4.17.13: L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine ,
3.4.21.50: a protein + H2O → a peptide + a peptide ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.24.3: a collagen + H2O → n a peptide ,
3.5.1.10: 10-formyl-tetrahydrofolate + H2O → formate + tetrahydrofolate + H+ ,
3.5.1.16: N-acetyl-L-ornithine + H2O → L-ornithine + acetate ,
3.5.1.18: N-succinyl-L,L-2,6-diaminopimelate + H2O = L,L-diaminopimelate + succinate ,
3.5.1.19: nicotinamide + H2O → ammonium + nicotinate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.28: N-acetylmuramoyl-L-alaninate + H2O = N-acetylmuramate + L-alanine ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.31: N-formyl-L-methionine + H2O = L-methionine + formate ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.42: β-nicotinamide D-ribonucleotide + H2O → ammonium + β-nicotinate D-ribonucleotide ,
3.5.1.59: N-carbamoylsarcosine + 2 H+ + H2O → ammonium + CO2 + sarcosine ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O = a [protein] N-terminal L-methionine + formate ,
3.5.1.108: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + H2O → UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine + acetate ,
3.5.1.-: an [L-2-aminoadipate carrier protein]-L-ornithine + H2O → L-ornithine + a [LysW protein]-L-glutamate ,
3.5.1.-: pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
3.5.2.3: (S)-dihydroorotate + H2O ← N-carbamoyl-L-aspartate + H+ ,
3.5.2.6: a β-lactam + H2O = a substituted β-amino acid ,
3.5.2.14: N-methylhydantoin + ATP + 2 H2O → N-carbamoylsarcosine + ADP + phosphate + 2 H+ ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.9: 5,10-methenyltetrahydrofolate + H2O ↔ 10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ← 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.13: CTP + H+ + H2O = UTP + ammonium ,
3.5.4.13: dCTP + H+ + H2O → ammonium + dUTP ,
3.5.4.16: GTP + H2O = formate + 7,8-dihydroneopterin triphosphate + H+ ,
3.5.4.19: 1-(5-phospho-β-D-ribosyl)-AMP + H2O → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ,
3.5.4.21: creatinine + H+ + H2O → ammonium + N-methylhydantoin ,
3.5.4.25: GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+ ,
3.5.4.26: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ + H2O → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.11: (polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.22: NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ ,
3.6.1.31: 1-(5-phospho-β-D-ribosyl)-ATP + H2O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H+ ,
3.6.1.40: pppGpp + H2O → ppGpp + phosphate + H+ ,
3.6.1.41: 5',5'''-diadenosine tetraphosphate + H2O = 2 ADP + 2 H+ ,
3.6.1.54: UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.14: ATP + 4 H+[in] + H2O ↔ ADP + phosphate + 5 H+[out] ,
3.6.3.27: ATP + phosphate[periplasmic space] + H2O → ADP + 2 phosphate[cytosol] + H+ ,
3.6.4.12: a double-helix DNA + ATP + H2O → an unwound double-stranded DNA + ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
4.1.1.11: L-aspartate + H+ = β-alanine + CO2 ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.20: meso-diaminopimelate + H+ = CO2 + L-lysine ,
4.1.1.21: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ ← 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + CO2 ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.31: oxaloacetate + phosphate ← phosphoenolpyruvate + hydrogen carbonate ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → coproporphyrinogen III + 4 CO2 ,
4.1.1.37: uroporphyrinogen-I + 4 H+ = coproporphyrinogen I + 4 CO2 ,
4.1.1.48: 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O ,
4.1.1.49: oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.72: 3-methyl-2-oxobutanoate + H+ → isobutanal + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate → acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.8: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate → indole + D-glyceraldehyde 3-phosphate ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.13: β-D-fructofuranose 1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde ,
4.1.2.17: L-fuculose 1-phosphate = L-lactaldehyde + dihydroxyacetone phosphate ,
4.1.2.-: DL-allothreonine = acetaldehyde + glycine ,
4.1.3.27: chorismate + L-glutamine → anthranilate + L-glutamate + pyruvate + H+ ,
4.1.3.34: (3S)-citryl-CoA → oxaloacetate + acetyl-CoA ,
4.1.3.38: 4-amino-4-deoxychorismate → 4-aminobenzoate + pyruvate + H+ ,
4.1.99.12: D-ribulose 5-phosphate → formate + 1-deoxy-L-glycero-tetrulose 4-phosphate + H+ ,
4.1.99.17: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + carbon monoxide + 3 H+ ,
4.1.99.19: L-tyrosine + S-adenosyl-L-methionine + a reduced electron acceptor → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + an oxidized electron acceptor + 2 H+ ,
4.2.1.1: hydrogen carbonate + H+ ← CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.3: citrate = D-threo-isocitrate ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylbutanoate → 3-methyl-2-oxobutanoate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylpentanoate → (S)-3-methyl-2-oxopentanoate + H2O ,
4.2.1.10: 3-dehydroquinate → 3-dehydroshikimate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.19: D-erythro-imidazole-glycerol-phosphate → imidazole acetol-phosphate + H2O ,
4.2.1.20: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O ,
4.2.1.24: 2 5-amino-levulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.33: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate ,
4.2.1.47: GDP-α-D-mannose = GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.51: prephenate + H+ = 2-oxo-3-phenylpropanoate + CO2 + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.96: 4α-hydroxy-tetrahydrobiopterin → 7,8-dihydrobiopterin + H2O ,
4.2.1.104: cyanate + hydrogen carbonate + H+ → carbamate + CO2 ,
4.2.1.104: cyanate + hydrogen carbonate + 3 H+ = ammonium + 2 CO2 ,
4.2.1.109: 5-methylthioribulose 1-phosphate → 5-(methylthio)-2,3-dioxopentyl phosphate + H2O ,
4.2.1.122: L-serine + indole → L-tryptophan + H2O ,
4.2.1.126: N-acetyl-β-muramate 6-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + (R)-lactate ,
4.2.1.-: 5-chloro-5-deoxy-D-ribonate = 5-chloro-4-hydroxy-2-oxopentanoate + H2O ,
4.2.3.1: O-phospho-L-homoserine + H2O → L-threonine + phosphate ,
4.2.3.4: 3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate ,
4.2.3.5: 5-enolpyruvyl-shikimate 3-phosphate → chorismate + phosphate ,
4.3.2.1: canavaninosuccinate = L-canavanine + fumarate ,
4.3.2.1: L-arginino-succinate → L-arginine + fumarate ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.3.7: pyruvate + L-aspartate-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ ,
4.4.1.21: S-ribosyl-L-homocysteine → L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.6.1.12: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol → 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + CMP ,
4.99.1.1: protoporphyrin IX + Fe2+ → protoheme IX + 2 H+ ,
4.99.1.4: sirohydrochlorin + Fe2+ → siroheme + 2 H+ ,
5.1.1.1: L-alanine → D-alanine ,
5.1.1.3: L-glutamate → D-glutamate ,
5.1.1.7: L,L-diaminopimelate = meso-diaminopimelate ,
5.1.3.1: D-ribulose 5-phosphate → D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.20: ADP-D-glycero-β-D-manno-heptose = ADP-L-glycero-β-D-manno-heptose ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.6: D-ribose 5-phosphate ← D-ribulose 5-phosphate ,
5.3.1.8: α-D-mannose 6-phosphate ← β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: α-D-glucose 6-phosphate → β-D-fructofuranose 6-phosphate ,
5.3.1.16: 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide → phosphoribulosylformimino-AICAR-P ,
5.3.1.23: S-methyl-5-thio-α-D-ribose 1-phosphate → 5-methylthioribulose 1-phosphate ,
5.3.1.24: N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate ,
5.3.1.28: D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.5: 5-(methylthio)-2,3-dioxopentyl phosphate → 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H+ ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.14: a trans2-decenoyl-[acp] → a cis3-decenoyl-[acp] ,
5.3.99.10: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate → 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.5: α-D-glucose 1-phosphate = D-glucopyranose 6-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate → 2-deoxy-D-ribose 5-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate → D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ← α-D-mannose 6-phosphate ,
5.4.2.10: D-glucosamine 1-phosphate ← D-glucosamine 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.2.12: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.3.8: glutamate-1-semialdehyde → 5-amino-levulinate ,
5.4.99.5: chorismate → prephenate ,
5.4.99.18: N5-carboxyaminoimidazole ribonucleotide → 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ,
5.5.1.4: D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.3: linoleate + ATP + coenzyme A → linoleoyl-CoA + AMP + diphosphate ,
6.2.1.3: oleate + ATP + coenzyme A → oleoyl-CoA + AMP + diphosphate ,
6.2.1.3: palmitate + ATP + coenzyme A → palmitoyl-CoA + AMP + diphosphate ,
6.2.1.3: pristanate + ATP + coenzyme A → pristanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2-methyl branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2-methyl branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: phytenate + ATP + coenzyme A → phytenoyl-CoA + AMP + diphosphate ,
6.2.1.3: an odd numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → an odd numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.3: a 3-methyl-branched 2,3,4-saturated fatty acid + ATP + coenzyme A → a 3-methyl-branched 2,3,4-saturated fatty acyl-CoA + AMP + diphosphate ,
6.2.1.3: (15Z)-tetracosenoate + ATP + coenzyme A → (Z)-15-tetracosenoyl-CoA + AMP + diphosphate ,
6.2.1.3: eicosapentaenoate + ATP + coenzyme A → eicosapentaenoyl-CoA + AMP + diphosphate ,
6.2.1.3: octanoate + ATP + coenzyme A → octanoyl-CoA + AMP + diphosphate ,
6.2.1.3: ATP + α-linolenate + coenzyme A → α-linolenoyl-CoA + AMP + diphosphate ,
6.2.1.3: a long-chain fatty acid + ATP + coenzyme A → a long-chain acyl-CoA + AMP + diphosphate ,
6.2.1.3: decanoate + ATP + coenzyme A → decanoyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.4: itaconate + GTP + coenzyme A → itaconyl-CoA + GDP + phosphate ,
6.2.1.4: succinate + GTP + coenzyme A ↔ succinyl-CoA + GDP + phosphate ,
6.2.1.5: succinate + ATP + coenzyme A ↔ succinyl-CoA + ADP + phosphate ,
6.2.1.14: pimelate + ATP + coenzyme A → pimeloyl-CoA + AMP + diphosphate ,
6.2.1.18: citrate + ATP + coenzyme A → (3S)-citryl-CoA + ADP + phosphate ,
6.2.1.-: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acid + ATP + coenzyme A → a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.5: ammonium + ATP + nicotinate adenine dinucleotide → AMP + NAD+ + diphosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + ADP + phosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + AMP + diphosphate + H+ ,
6.3.2.4: 2 D-alanine + ATP → D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.8: L-alanine + UDP-N-α-D-acetylmuramate + ATP → UDP-N-acetylmuramoyl-L-alanine + ADP + phosphate + H+ ,
6.3.2.9: UDP-N-acetylmuramoyl-L-alanine + D-glutamate + ATP → UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + ADP + phosphate + H+ ,
6.3.2.10: UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + D-alanyl-D-alanine + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.12: L-glutamate + 7,8-dihydropteroate + ATP → ADP + 7,8-dihydrofolate + phosphate + H+ ,
6.3.2.13: UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: UDP-N-α-D-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.-: L-glutamate + a [LysW protein]-L-glutamate + ATP → an [L-2-aminoadipate carrier protein]-L-glutamate + ADP + phosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: ATP + 5-formyl-tetrahydrofolate → 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.3.3: CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+ ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.3: ATP + formate + tetrahydrofolate → ADP + 10-formyl-tetrahydrofolate + phosphate ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: O-ureidohomoserine + L-aspartate + ATP → canavaninosuccinate + AMP + diphosphate + H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.13: 5-phospho-β-D-ribosylamine + ATP + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.16: ammonium + CO2 + 2 ATP + H2O → carbamoyl-phosphate + 2 ADP + phosphate + 3 H+ ,
6.3.4.18: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + hydrogen carbonate → N5-carboxyaminoimidazole ribonucleotide + ADP + phosphate + 2 H+ ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → L-glutamate + AMP + NAD+ + diphosphate + H+ ,
6.3.5.2: XMP + L-glutamine + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → L-glutamate + ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + phosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → L-glutamate + carbamoyl-phosphate + 2 ADP + phosphate + 2 H+ ,
6.4.1.1: pyruvate + hydrogen carbonate + ATP → oxaloacetate + ADP + phosphate + H+ ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.7: ATP + 2-oxoglutarate + CO2 + H2O → oxalosuccinate + ADP + phosphate + 2 H+ ,
6.5.1.1: (deoxynucleotides)(m) + ATP + (deoxynucleotides)n → AMP + (deoxynucleotides)(n+m) + diphosphate ,
6.5.1.2: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
glutathioselenol + NADPH + 2 H+ ← hydrogen selenide + glutathione + NADP+ ,
selenodiglutathione + NADPH → glutathioselenol + glutathione + NADP+ ,
glycine + oxygen → 2-iminoacetate + hydrogen peroxide + H+ ,
an S-sulfanyl-[L-cysteine desulfurase] + a ThiI sulfur-carrier protein → an [L-cysteine desulfurase] + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
aminocarboxymuconate semialdehyde → quinolinate + H2O ,
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
glycine + tetrahydrofolate + NAD+ → ammonium + CO2 + 5,10-methylenetetrahydrofolate + NADH ,
n S0 + HS- → (sulfide)n+1 + H+ ,
formate + H+ → CO2 + H2 ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate + H+ ,
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with L,D cross-links (mycobacteria) + ω, mono-trans,octa-cis-decaprenyl diphosphate + 4 D-alanine + H+ ,
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → a peptidoglycan with D,D cross-links (mycobacteria) + 4 D-alanine + ω, mono-trans,octa-cis-decaprenyl diphosphate + H+ ,
ammonium[out] → ammonium[in] ,
nitrate[out] + 2 H+[out] + 2 e- → nitrite[out] + H2O[out] ,
(2R,3S)-3-isopropylmalate + NAD+ → (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ ,
(2S)-2-isopropyl-3-oxosuccinate + H+ → 4-methyl-2-oxopentanoate + CO2 ,
5 S0 + oxygen + 4 H2O → sulfite + thiosulfate + 2 hydrogen sulfide + 3 H+ ,
deethylsimazine + H2O = N-ethylammeline + chloride + H+ ,
ribose-1-arsenate + dihydrolipoate + H+ = D-ribofuranose + arsenite + (R)-lipoate ,
2-oxoglutarate + coenzyme A + NAD+ → succinyl-CoA + CO2 + NADH ,
histidinol + NAD+ → histidinal + NADH + H+ ,
histidinal + NAD+ + H2O → L-histidine + NADH + 2 H+ ,
4-phospho-hydroxy-L-threonine + NAD+(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+ ,
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + H+ → 3-amino-1-hydroxyacetone 1-phosphate + CO2 ,
a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP = a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
dimethyl sulfoxide + NADH + H+ = dimethyl sulfide + NAD+ + H2O ,
4 H+[in] → 4 H+[out] ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+ ,
S-adenosyl-L-methionine + precorrin-1 → S-adenosyl-L-homocysteine + precorrin-2 ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
carbamate + 2 H+ → ammonium + CO2 ,
XMP + ammonium + ATP = GMP + AMP + diphosphate + 2 H+ ,
(2R,3S)-3-isopropylmalate ← 2-isopropylmaleate + H2O ,
(2S)-2-isopropylmalate → 2-isopropylmaleate + H2O ,
ATP + UTP + ammonium = ADP + CTP + phosphate + 2 H+ ,
citrate ↔ cis-aconitate + H2O ,
cis-aconitate + H2O ↔ D-threo-isocitrate ,
Mg2+[periplasmic space] → Mg2+[cytosol] ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
aldehydo-D-ribose ↔ D-ribopyranose ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
sulfite + H+ ↔ bisulfite ,
glutathione + intracellular S0 → S-sulfanylglutathione ,
(S)-2-acetolactate + an oxidized electron acceptor + H+ → diacetyl + CO2 + a reduced electron acceptor ,
formaldehyde + tetrahydrofolate → 5,10-methylenetetrahydrofolate + H2O ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
aldehydo-D-ribose ↔ D-ribofuranose ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
glutathione + S0 → S-sulfanylglutathione ,
(R)-methylmalonate-semialdehyde ↔ (S)-methylmalonate-semialdehyde ,
2-iminoacetate + H+ + H2O → glyoxylate + ammonium ,
NADH + H2O → (R)-NADHX ,
NADH + H2O → (S)-NADHX ,
ammonia + H+ ↔ ammonium ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
(S)-4,5-dihydroxypentan-2,3-dione → (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
(S)-4,5-dihydroxypentan-2,3-dione → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
2'-hydroxy-β-oxo-L-tyrosine-S-[NovH protein] + NADP+ = 3-amino-4,7-dihydroxy-coumarin + a NovH peptidyl-carrier protein + NADPH + H+


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