Aquifex aeolicus VF5 Pathway: ethanol degradation I

Pathway diagram: ethanol degradation I

If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.

Locations of Mapped Genes:

Schematic showing all replicons, marked with selected genes

Synonyms: acetyl-CoA biosynthesis (from alcohol)

Superclasses: Degradation/Utilization/Assimilation Alcohols Degradation Ethanol Degradation

Pathway Summary from MetaCyc:
Although Escherichia coli encodes the enzymes constituting this pathway by which ethanol can be degraded to acetyl-CoA and thereby enter central metabolism, in wild type ethanol is not metabolized at a sufficient rate to support growth. Certain mutant strains, however, with altered patterns of gene expression can grow on ethanol as source of carbon and energy.

Variants: ethanol degradation II

Pathway Evidence Glyph:

Pathway evidence glyph

Key to pathway glyph edge colors: ?

  An enzyme catalyzing this reaction is present in this organism
  The reaction and any enzyme that catalyzes it (if one has been identified) is unique to this pathway

Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International

References Related to Enzymes, Genes, Subpathways, and Substrates of this Pathway

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Rubio06: Rubio S, Larson TR, Gonzalez-Guzman M, Alejandro S, Graham IA, Serrano R, Rodriguez PL (2006). "An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment." Plant Physiol 140(3);830-43. PMID: 16415216

Thauer77: Thauer RK, Jungermann K, Decker K (1977). "Energy conservation in chemotrophic anaerobic bacteria." Bacteriol Rev 1977;41(1);100-80. PMID: 860983

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Page generated by SRI International Pathway Tools version 19.0 on Wed Oct 7, 2015, biocyc13.