Aquifex aeolicus VF5 Pathway: ethanol degradation I
Inferred by computational analysis

Pathway diagram: ethanol degradation I

If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.

Locations of Mapped Genes:

Schematic showing all replicons, marked with selected genes

Synonyms: acetyl-CoA biosynthesis (from alcohol)

Superclasses: Degradation/Utilization/AssimilationAlcohols DegradationEthanol Degradation

Pathway Summary from MetaCyc:
Although Escherichia coli encodes the enzymes constituting this pathway by which ethanol can be degraded to acetyl-CoA and thereby enter central metabolism, in wild type ethanol is not metabolized at a sufficient rate to support growth. Certain mutant strains, however, with altered patterns of gene expression can grow on ethanol as source of carbon and energy.

Variants: ethanol degradation II

Pathway Evidence Glyph:

Pathway evidence glyph

This organism is in the expected taxonomic range for this pathway.

Key to pathway glyph edge colors:

  An enzyme catalyzing this reaction is present in this organism
  The reaction is unique to this pathway in MetaCyc

Imported from MetaCyc 08-Aug-2014 by Subhraveti P, SRI International

References Related to Enzymes, Genes, Subpathways, and Substrates of this Pathway

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Rubio06: Rubio S, Larson TR, Gonzalez-Guzman M, Alejandro S, Graham IA, Serrano R, Rodriguez PL (2006). "An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment." Plant Physiol 140(3);830-43. PMID: 16415216

Thauer77: Thauer RK, Jungermann K, Decker K (1977). "Energy conservation in chemotrophic anaerobic bacteria." Bacteriol Rev 1977;41(1);100-80. PMID: 860983

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Page generated by SRI International Pathway Tools version 19.5 on Sun Nov 29, 2015, BIOCYC13A.