Aquifex aeolicus VF5 Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase: purH

In Pathway: inosine-5'-phosphate biosynthesis I, inosine-5'-phosphate biosynthesis II

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphoribosylaminoimidazolecarboxamide formyltransferase

Enzyme Commission Synonyms: 5-amino-4-imidazolecarboxamide ribonucleotide transformylase, AICAR transformylase, 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase, 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase, 5-amino-4-imidazolecarboxamide ribotide transformylase, AICAR formyltransferase, aminoimidazolecarboxamide ribonucleotide transformylase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 18.96Inferred by computational analysis [Latendresse13]

Citations: [Hartman59]

Gene-Reaction Schematic

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:

Imported from MetaCyc 08-Aug-2014 by Subhraveti P, SRI International


Hartman59: Hartman SC, Buchanan JM (1959). "Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reactions." J Biol Chem 234(7);1812-6. PMID: 13672969

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

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