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Aquifex aeolicus VF5 Reaction: 6.3.3.3

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 6.3.3.3

Enzymes and Genes:
dethiobiotin synthetase : bioD

In Pathway: biotin biosynthesis from 8-amino-7-oxononanoate I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: dethiobiotin synthase

Enzyme Commission Synonyms: desthiobiotin synthase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -26.029968 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
CTP has half the activity of ATP.

Citations: [Krell70]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC:6.3.3.3 , ENZYME:EC:6.3.3.3 , IUBMB-ExplorEnz:EC:6.3.3.3

Credits:
Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International


References

Krell70: Krell K, Eisenberg MA (1970). "The purification and properties of dethiobiotin synthetase." J Biol Chem 245(24);6558-66. PMID: 4921568

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


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Page generated by SRI International Pathway Tools version 19.0 on Fri Aug 28, 2015, biocyc14.