Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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Aquifex aeolicus VF5 Reaction: 3.6.1.31

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.1.31

Enzymes and Genes:
bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP Inferred by computational analysis : hisIE

In Pathway: histidine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphoribosyl-ATP diphosphatase

Enzyme Commission Synonyms: phosphoribosyl-ATP pyrophosphatase, phosphoribosyladenosine triphosphate pyrophosphatase, 1-(5-phosphoribosyl)-ATP diphosphohydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -124.32709 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The Neurospora crassa enzyme also catalyses the reactions of EC 1.1.1.23 (histidinol dehydrogenase) and EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase).

Citations: [SMITH65]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.6.1.31 , ENZYME:EC:3.6.1.31 , IUBMB-ExplorEnz:EC:3.6.1.31

Credits:
Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

SMITH65: SMITH DW, AMES BN (1965). "PHOSPHORIBOSYLADENOSINE MONOPHOSPHATE, AN INTERMEDIATE IN HISTIDINE BIOSYNTHESIS." J Biol Chem 240;3056-63. PMID: 14342333


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Page generated by SRI International Pathway Tools version 18.5 on Mon Dec 22, 2014, biocyc12.