Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Aquifex aeolicus VF5 Reaction: 3.6.1.31

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.1.31

Enzymes and Genes:
bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP Inferred by computational analysis : hisIE

In Pathway: histidine biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: phosphoribosyl-ATP diphosphatase

Enzyme Commission Synonyms: phosphoribosyl-ATP pyrophosphatase, phosphoribosyladenosine triphosphate pyrophosphatase, 1-(5-phosphoribosyl)-ATP diphosphohydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -124.32709 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The Neurospora crassa enzyme also catalyses the reactions of EC 1.1.1.23 (histidinol dehydrogenase) and EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase).

Citations: [SMITH65]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.6.1.31 , ENZYME:EC:3.6.1.31 , IUBMB-ExplorEnz:EC:3.6.1.31

Credits:
Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

SMITH65: SMITH DW, AMES BN (1965). "PHOSPHORIBOSYLADENOSINE MONOPHOSPHATE, AN INTERMEDIATE IN HISTIDINE BIOSYNTHESIS." J Biol Chem 240;3056-63. PMID: 14342333


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Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, biocyc14.