Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Aquifex aeolicus VF5 Reaction: 3.6.1.1

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.6.1.1

Enzymes and Genes:
inorganic pyrophosphatase : ppa

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: inorganic diphosphatase

Enzyme Commission Synonyms: Diphosphate phosphohydrolase, Pyrophosphate phosphohydrolase, Inorganic diphosphatase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 4.1469727 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Specificity varies with the source and with the activating metal ion. The enzyme from some sources may be identical with EC 3.1.3.1 (alkaline phosphatase) or EC 3.1.3.9 (glucose-6-phosphatase). A form of this enzyme with a molecular mass of about 90 kDa is found in tonoplasts of plants and fungi, where it imports protons from the cytosol into the vacuolar lumen.

Citations: [Bailey44, KUNITZ52, RAFTER60]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:3.6.1.1 , ENZYME:EC:3.6.1.1 , IUBMB-ExplorEnz:EC:3.6.1.1

Credits:
Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International


References

Bailey44: Bailey K, Webb EC (1944). "Purification and properties of yeast pyrophosphatase." Biochem J 38(5);394-8. PMID: 16747821

KUNITZ52: KUNITZ M (1952). "Crystalline inorganic pyrophosphatase isolated from baker's yeast." J Gen Physiol 35(3);423-50. PMID: 14898026

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

RAFTER60: RAFTER GW (1960). "Pyrophosphate metabolism in liver mitochondria." J Biol Chem 235;2475-7. PMID: 14435825


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Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, BIOCYC13A.