Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Aquifex aeolicus VF5 Reaction: 2.7.1.130

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.130

Enzymes and Genes:
hypothetical protein Inferred by computational analysis : aq_1656

In Pathway: lipid IVA biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tetraacyldisaccharide 4′-kinase

Enzyme Commission Synonyms: lipid-A 4'-kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -17.31247 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Involved with EC 2.3.1.129 (acyl-[acyl-carrier- protein]—UDP-N-acetylglucosamine O-acyltransferase) and EC 2.4.1.182 (lipid-A-disaccharide synthase) in the biosynthesis of the phosphorylated glycolipid, lipid A, in the outer membrane of Escherichia coli.

Citations: [Ray87]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.7.1.130 , ENZYME:EC:2.7.1.130 , IUBMB-ExplorEnz:EC:2.7.1.130

Credits:
Imported from MetaCyc 08-Aug-2014 by Subhraveti P , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ray87: Ray BL, Raetz CR (1987). "The biosynthesis of gram-negative endotoxin. A novel kinase in Escherichia coli membranes that incorporates the 4'-phosphate of lipid A." J Biol Chem 262(3);1122-8. PMID: 3027079


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Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, BIOCYC14B.