Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Current and Filled Pathway Holes of <i>Aquifex aeolicus</i> VF5

Current and Filled Pathway Holes of Aquifex aeolicus VF5

A pathway hole is a reaction for which no corresponding enzyme has been identified in the genome.

This report includes two tables regarding pathway holes in Aquifex aeolicus VF5:

Current Pathway Holes: A list of reactions within metabolic pathways of Aquifex aeolicus VF5 for which no corresponding enzyme has been found.

Filled Pathway Holes: A list of former pathway holes within metabolic pathways of Aquifex aeolicus VF5 which have been filled with the assistance of the Pathway Hole Filler.




Current Pathway Holes

This table lists reactions within metabolic pathways of Aquifex aeolicus VF5 for which no corresponding enzyme has been identified in the genome. The presence of those enzymes is suggested by the presence of the pathway.

107 pathway holes were identified.

Reaction EC# Pathway(s) needing this reaction
selenite + AMP + glutathione disulfide + 3 H+ ← adenosine 5'-phosphoselenate + 2 glutathione 1.8.4.9 selenate reduction
glutathioselenol + NADPH + 2 H+ → hydrogen selenide + glutathione + NADP+ [none] selenate reduction
selenodiglutathione + NADPH → glutathioselenol + glutathione + NADP+ [none] selenate reduction
N-carbamoylsarcosine + 2 H+ + H2O → ammonium + CO2 + sarcosine 3.5.1.59 creatinine degradation II
sarcosine + an oxidized electron-transfer flavoprotein + H2O → glycine + formaldehyde + a reduced electron-transfer flavoprotein 1.5.8.3 creatinine degradation II
sarcosine + oxygen + H2O → glycine + formaldehyde + hydrogen peroxide 1.5.3.1 creatinine degradation II
creatinine + H+ + H2O → ammonium + N-methylhydantoin 3.5.4.21 creatinine degradation II
8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ 3.6.1.- oxidized GTP and dGTP detoxification
a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor 3.1.26.12 tRNA processing
a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate 3.1.13.1 tRNA processing
a tRNA precursor with a 5' extension + H2O → an uncharged tRNA + a single-stranded RNA 3.1.26.5 tRNA processing
a tRNA precursor with a short 3' extension → an uncharged tRNA + n a nucleoside 5'-monophosphate 3.1.13.5 tRNA processing
a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA 3.1.26.5 tRNA processing
a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate 3.1.13.5 tRNA processing
a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor 3.1.26.12 tRNA processing
3-phospho-L-serine + 2-oxoglutarate ← L-glutamate + 3-phospho-hydroxypyruvate 2.6.1.52 serine biosynthesis
3-phospho-L-serine + H2O → L-serine + phosphate 3.1.3.3 serine biosynthesis
tetrahydrobiopterin + L-phenylalanine + oxygen → L-tyrosine + 4α-hydroxy-tetrahydrobiopterin 1.14.16.1 phenylalanine degradation I (aerobic)
tetrahydrobiopterin + NAD+ ← 7,8-dihydrobiopterin + NADH + H+ 1.5.1.- phenylalanine degradation I (aerobic)
hydrogen carbonate + H+ ← CO2 + H2O 4.2.1.1 cyanate degradation
2'-deoxyguanosine + ATP → dGMP + ADP + H+ 2.7.1.74/2.7.1.113/2.7.1.145 purine deoxyribonucleosides salvage
2'-deoxyadenosine + ATP → dAMP + ADP + H+ 2.7.1.74/2.7.1.76/2.7.1.145 purine deoxyribonucleosides salvage
dGMP + ATP → dGDP + ADP 2.7.4.12/2.7.4.13 purine deoxyribonucleosides salvage
ATP + dAMP → ADP + dADP 2.7.4.11/2.7.4.13 purine deoxyribonucleosides salvage
D-glucopyranose 6-phosphate → 1D-myo-inositol 3-monophosphate 5.5.1.4 myo-inositol biosynthesis
ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ 2.7.2.2 citrulline degradation
ammonia + 6 an oxidized c-type cytochrome + 2 H2O ← nitrite + 6 a reduced c-type cytochrome + 7 H+ 1.7.2.2 nitrate reduction IV (dissimilatory)
2 hydrogen peroxide → 2 H2O + oxygen 1.11.1.6/1.11.1.21 superoxide radicals degradation
XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate 2.4.2.22 xanthine and xanthosine salvage
AMP + diphosphate ← adenine + 5-phospho-α-D-ribose 1-diphosphate 2.4.2.7 adenine and adenosine salvage I
guanosine + H2O → D-ribofuranose + guanine 3.2.2.1 guanine and guanosine salvage II
an octanoyl-[acp] + a [lipoyl-carrier protein] → a [lipoyl-carrier protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein] + H+ 2.3.1.181 lipoate biosynthesis and incorporation I
an oxidized thioredoxin + 2 e- = a reduced thioredoxin [none] thioredoxin pathway
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate 2.5.1.54 3-dehydroquinate biosynthesis I
ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ 2.7.1.50 4-methyl-5(beta-hydroxyethyl)thiazole salvage (yeast)
a guanine34 in tRNA + preQ1 → a 7-aminomethyl-7-deazaguanosine34 in tRNA + guanine 2.4.2.29 queuosine biosynthesis
an epoxyqueuosine34 in tRNA ← a queuosine34 in tRNA [none] queuosine biosynthesis
2 an oxidized c-type cytochrome + an ubiquinol → 2 a reduced c-type cytochrome + an ubiquinone 1.10.2.2 aerobic respiration (cytochrome c)
N-acetyl-β-muramate 6-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + (R)-lactate 4.2.1.126 anhydromuropeptides recycling
1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ 2.7.1.170 anhydromuropeptides recycling
N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate 3.2.1.52 anhydromuropeptides recycling
N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate 3.5.1.25 anhydromuropeptides recycling
L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine 3.4.17.13 anhydromuropeptides recycling
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ [none] isoleucine biosynthesis I (from threonine)
a (3R)-3-hydroxystearoyl-[acp] → a trans-octadec-2-enoyl-[acp] + H2O 2.3.1.86/4.2.1.59 stearate biosynthesis II (bacteria and plants)
a stearoyl-[acp] + H2O → stearate + a holo-[acyl-carrier protein] + H+ 3.1.2.14 stearate biosynthesis II (bacteria and plants)
a cis-vaccenoyl-[acp] + H2O → cis-vaccenate + a holo-[acyl-carrier protein] + H+ 3.1.2.14 cis-vaccenate biosynthesis
a (3R)-3-hydroxy-cis-vaccenoyl-[acp] → a 2-trans-11-cis-vaccen-2-enoyl-[acp] + H2O 4.2.1.59 cis-vaccenate biosynthesis
a [methyl-Co(III) corrinoid Fe-S protein] + tetrahydrofolate ← a [Co(I) corrinoid Fe-S protein] + 5-methyl-tetrahydrofolate 2.1.1.258 reductive acetyl coenzyme A pathway
acetyl-CoA + a [Co(I) corrinoid Fe-S protein] ← carbon monoxide + a [methyl-Co(III) corrinoid Fe-S protein] + coenzyme A 2.3.1.169 reductive acetyl coenzyme A pathway
carbon monoxide + an oxidized ferredoxin + H2O ← CO2 + a reduced ferredoxin + H+ 1.2.7.4 reductive acetyl coenzyme A pathway
pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate 1.4.3.5 pyridoxal 5'-phosphate biosynthesis I
2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate → 4-phospho-hydroxy-L-threonine + 2-oxoglutarate 2.6.1.52 pyridoxal 5'-phosphate biosynthesis I
pyruvate + L-valine → L-alanine + 3-methyl-2-oxobutanoate 2.6.1.66 alanine biosynthesis I
L-tyrosine + 2-oxoglutarate ← 4-hydroxyphenylpyruvate + L-glutamate 2.6.1.5/2.6.1.57 tyrosine biosynthesis I
acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate 6.2.1.1 ethanol degradation II
UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ 3.6.1.54 lipid IVA biosynthesis
a (3R)-3-hydroxymyristoyl-[acp] + UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine → UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + a holo-[acyl-carrier protein] + H+ 2.3.1.191 lipid IVA biosynthesis
a trans2-decenoyl-[acp] → a cis3-decenoyl-[acp] 5.3.3.14 cis-dodecenoyl biosynthesis
α-D-ribose-1-phosphate → D-ribose 5-phosphate 5.4.2.7 purine ribonucleosides degradation
acetyl-CoA + phosphate → acetyl phosphate + coenzyme A 2.3.1.8 mixed acid fermentation
ATP + acetate ← ADP + acetyl phosphate 2.7.2.1 mixed acid fermentation
a limit dextrin + H2O → maltotetraose + a debranched limit dextrin 3.2.1.33 glycogen degradation I
maltotriose + H2O → maltose + D-glucopyranose 3.2.1.20 glycogen degradation I
NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ 3.6.1.22 NAD salvage pathway I
β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ 3.2.2.14 NAD salvage pathway I
a (3R)-3-hydroxyhexanoyl-[acp] → a trans hex-2-enoyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants)
a (3R)-3-hydroxybutanoyl-[acp] → a crotonyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants)
a (3R)-3-hydroxyoctanoyl-[acp] → a trans oct-2-enoyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants)
a (3R)-3-hydroxydodecanoyl-[acp] → a trans dodec-2-enoyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants)
a (3R)-3-hydroxypalmitoyl-[acp] → a trans hexadecenoyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants)
a palmitoyl-[acp] + H2O → palmitate + a holo-[acyl-carrier protein] + H+ 3.1.2.14 palmitate biosynthesis II (bacteria and plants)
a dodecanoyl-[acp] + H2O → a holo-[acyl-carrier protein] + laurate + H+ 3.1.2.21 palmitate biosynthesis II (bacteria and plants)
a (3R)-3-hydroxydecanoyl-[acp] → a trans2-decenoyl-[acp] + H2O 2.3.1.85/2.3.1.86/4.2.1.59 palmitate biosynthesis II (bacteria and plants), cis-dodecenoyl biosynthesis
tetrahydrofolate + NADP+ ← 7,8-dihydrofolate + NADPH + H+ 1.5.1.3 formylTHF biosynthesis, tetrahydrofolate biosynthesis
S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor 2.1.1.- methionine degradation I (to homocysteine), S-adenosyl-L-methionine cycle II
a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A 2.3.1.51 CDP-diacylglycerol biosynthesis I
GMP + ATP → GDP + ADP 2.7.4.8 guanosine ribonucleotides de novo biosynthesis
adenosine + H+ + H2O → ammonium + inosine 3.5.4.4 adenine and adenosine salvage III, purine ribonucleosides degradation
xanthine + NAD+ + H2O → urate + NADH + H+ 1.17.1.4 urate biosynthesis/inosine 5'-phosphate degradation
2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine 3.5.4.4 purine deoxyribonucleosides degradation
a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + a [lipoyl-carrier protein] → a [lipoyl-carrier protein] N6-lipoyl-L-lysine + [glycine cleavage system lipoyl-carrier protein]-L-lysine 2.3.1.200 lipoate salvage II
(R)-pantothenate + ATP → D-4'-phosphopantothenate + ADP + H+ 2.7.1.33 phosphopantothenate biosynthesis I
6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ 3.1.1.31 pentose phosphate pathway (oxidative branch) I
protoporphyrinogen IX + 3 a menaquinone → protoporphyrin IX + 3 a menaquinol 1.3.5.3 heme biosynthesis from uroporphyrinogen-III II (anaerobic)
L-homocysteine + 5-methyl-tetrahydrofolate → L-methionine + tetrahydrofolate 2.1.1.13 formylTHF biosynthesis, folate transformations I
trimethyl sulfonium + tetrahydrofolate ← dimethyl sulfide + 5-methyl-tetrahydrofolate + H+ 2.1.1.19 folate transformations I
5,10-methylenetetrahydrofolate + NAD+ → 5,10-methenyltetrahydrofolate + NADH 1.5.1.15 folate transformations I
fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate 3.1.3.11 gluconeogenesis I
oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP 4.1.1.49 gluconeogenesis I
pyruvate + ATP ↔ phosphoenolpyruvate + ADP + H+ 2.7.1.40 mixed acid fermentation, respiration (anaerobic)
oxaloacetate + phosphate ← phosphoenolpyruvate + hydrogen carbonate 4.1.1.31 mixed acid fermentation, respiration (anaerobic)
formate + acetyl-CoA ← pyruvate + coenzyme A 2.3.1.54 mixed acid fermentation, respiration (anaerobic)
N-acetyl-L-ornithine + H2O → L-ornithine + acetate 3.5.1.16 ornithine biosynthesis
a limit dextrin with short branches + H2O → a debranched limit dextrin + β-D-glucose 3.2.1.33 glycogen degradation II
β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate 5.3.1.9 gluconeogenesis I, UDP-N-acetyl-D-glucosamine biosynthesis I, GDP-mannose biosynthesis
pppGpp + H2O → ppGpp + phosphate + H+ 3.6.1.40 ppGpp biosynthesis
dUMP + 5,10-methylenetetrahydrofolate → dTMP + 7,8-dihydrofolate 2.1.1.45 pyrimidine deoxyribonucleotides de novo biosynthesis II, formylTHF biosynthesis
L-tyrosine + S-adenosyl-L-methionine + a reduced electron acceptor → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + an oxidized electron acceptor + 2 H+ 4.1.99.19 thiazole biosynthesis I (E. coli)
isopentenyl diphosphate ↔ dimethylallyl diphosphate 5.3.3.2 methylerythritol phosphate pathway
a palmitoleoyl-[acp] + H2O → palmitoleate + a holo-[acyl-carrier protein] + H+ 3.1.2.14 palmitoleate biosynthesis I
CTP + H2O → CDP + phosphate + H+ 3.6.1.15 pyrimidine deoxyribonucleotides de novo biosynthesis III
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate [none] flavin biosynthesis I (bacteria and plants)
succinate[in] + an ubiquinone → fumarate[in] + an ubiquinol 1.3.5.1 TCA cycle I (prokaryotic), aerobic respiration (cytochrome c)
tRNAgln + L-glutamine + ATP + H+ → L-glutaminyl-tRNAgln + AMP + diphosphate 6.1.1.18 tRNA charging
tRNAasn + L-asparagine + ATP + H+ → L-asparaginyl-tRNAasn + AMP + diphosphate 6.1.1.22 tRNA charging
ATP + 2-oxoglutarate + CO2 + H2O → oxalosuccinate + ADP + phosphate + 2 H+ 6.4.1.7 reductive TCA cycle II



Filled Pathway Holes

Key:
Hole-filler The gene whose product is predicted to catalyze the missing reaction.
Hole EC# The EC number of the missing reaction (links to the reaction page).
P(has-function) The probability that the hole-filler catalyzes the missing reaction as determined by the PHFiller.
All functions of hole-filler All current annotations of the hole-filler, including the function of the missing reaction to which it has been assigned.
Pathway(s) requiring this reaction All metabolic pathways in which the pathway hole occurs in the database.

09:30:33 of Sunday, 12/21/2014 (GMT-8)

65 of 164 pathway holes were filled (39.6%).

Hole-filler Hole EC# P(has-function) All functions of hole-filler Pathway(s) requiring this reaction
xylR 2.7.1.2 0.975 NagC/XylR family transcriptional regulator glycogen degradation I
ribD1 1.1.1.193 0.999 riboflavin specific deaminase flavin biosynthesis I (bacteria and plants)
ribF 2.7.7.2 0.999 riboflavin kinase flavin biosynthesis I (bacteria and plants)
gltA 4.1.3.34 0.996 citrate synthase reductive TCA cycle II
aq_1656 2.7.1.130 0.975 hypothetical protein lipid IVA biosynthesis
aspS 6.1.1.- 0.917 aspartyl-tRNA synthetase asparagine biosynthesis III (tRNA-dependent)
fabF 2.3.1.179 0.996 3-oxoacyl-ACP synthase cis-vaccenate biosynthesis
aq_1727 1.1.1.169 0.975 hypothetical protein phosphopantothenate biosynthesis I
aq_1731 6.3.3.2 0.975 hypothetical protein folate transformations I, formylTHF biosynthesis
proC 1.5.1.2 0.991 pyrroline carboxylate reductase proline biosynthesis I
folD 3.5.4.9 1.000 methylenetetrahydrofolate dehydrogenase tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate, folate transformations I, formylTHF biosynthesis, reductive acetyl coenzyme A pathway
folD 6.3.4.3 1.000 methylenetetrahydrofolate dehydrogenase folate polyglutamylation, folate transformations I, reductive acetyl coenzyme A pathway
gcsP1 2.1.2.10 0.992 glycine dehydrogenase subunit 2 glycine cleavage, GCVMULTI-RXN
serA 1.1.1.290 0.978 D-3-phosphoglycerate dehydrogenase pyridoxal 5'-phosphate biosynthesis I
umpS 2.4.2.10 0.966 uridine 5-monophosphate synthase UMP biosynthesis
thiD 2.7.1.49 1.000 HMP-P kinase hydroxymethylpyrimidine salvage
hisIE 3.6.1.31 0.999 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP histidine biosynthesis
aspC1 2.6.1.88 0.991 aspartate aminotransferase S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
masA 5.3.2.5 0.993 enolase-phosphatase E-1 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
masA 3.1.3.87 0.993 enolase-phosphatase E-1 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
imp2 3.1.3.15 0.917 myo-inositol-1(or 4)-monophosphatase histidine biosynthesis
aq_1996 3.5.1.42 0.978 hypothetical protein NAD salvage pathway I
eif 5.3.1.23 0.991 initiation factor eIF-2B subunit alpha S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
narB none 0.992 nitrate reductase narB respiration (anaerobic), mixed acid fermentation
phpA 3.1.13.1 0.995 polynucleotide phosphorylase/polyadenylase tRNA processing
purK 6.3.4.18 0.991 phosphoribosylaminoimidazole carboxylase ATPase subunit inosine-5'-phosphate biosynthesis I
gatA 3.5.1.- 0.917 aspartyl/glutamyl-tRNA amidotransferase subunit A lipoate salvage II
ribA 4.1.99.12 1.000 GTP cyclohydrolase II flavin biosynthesis I (bacteria and plants)
aq_036 2.7.7.18 0.975 hypothetical protein NAD salvage pathway I, NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde, NAD biosynthesis I (from aspartate)
ilvB 4.1.1.72 0.998 acetolactate synthase large subunit valine degradation II
pmu 5.4.2.7 0.975 phosphoglucomutase/phosphomannomutase 2'-deoxy-alpha-D-ribose 1-phosphate degradation
pmu 5.4.2.10 0.995 phosphoglucomutase/phosphomannomutase anhydromuropeptides recycling, UDP-N-acetyl-D-glucosamine biosynthesis I
pyrD 1.3.5.2 0.994 dihydroorotate dehydrogenase 1B UMP biosynthesis
xanB 2.7.7.13 0.999 mannose-6-phosphate isomerase/mannose-1-phosphate guanyl transferase GDP-mannose biosynthesis
fabZ 2.3.1.85/2.3.1.86/4.2.1.59 0.996 (3R)-hydroxymyristoyl-ACP dehydratase fatty acid elongation -- saturated
fabZ 4.2.1.59 0.990 (3R)-hydroxymyristoyl-ACP dehydratase palmitoleate biosynthesis I
fabZ 4.2.1.59 0.990 (3R)-hydroxymyristoyl-ACP dehydratase palmitoleate biosynthesis I
fabZ 4.2.1.59 0.990 (3R)-hydroxymyristoyl-ACP dehydratase cis-dodecenoyl biosynthesis
glmU 2.3.1.157 0.999 UDP-N-acetylglucosamine pyrophosphorylase anhydromuropeptides recycling, UDP-N-acetyl-D-glucosamine biosynthesis I
aq_707 none 0.975 hypothetical protein thiazole biosynthesis II (Bacillus)
mpg 2.7.7.27 0.997 mannose-1-phosphate guanyltransferase glycogen biosynthesis I (from ADP-D-Glucose)
lpdA 1.2.1.- 0.993 dihydrolipoamide dehydrogenase respiration (anaerobic)
lpdA none 0.993 dihydrolipoamide dehydrogenase folate transformations I, formylTHF biosynthesis
nifS2 2.8.1.7 1.000 FeS cluster formation protein NifS thiazole biosynthesis II (Bacillus), thiazole biosynthesis I (E. coli)
nifS2 none 1.000 FeS cluster formation protein NifS thiazole biosynthesis I (E. coli)
nifS2 none 0.993 FeS cluster formation protein NifS thiazole biosynthesis II (Bacillus)
murF 6.3.2.10 0.998 UDP-MurNAc-pentapeptide sythetase UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-DAP-containing)
surE 3.1.3.5 0.993 stationary phase survival protein SurE urate biosynthesis/inosine 5'-phosphate degradation
spoT 2.7.6.5 0.999 (p)ppGpp 3-pyrophosphohydrolase ppGpp biosynthesis
spoT 2.7.6.5 0.997 (p)ppGpp 3-pyrophosphohydrolase ppGpp biosynthesis
spoT 3.1.7.2 0.996 (p)ppGpp 3-pyrophosphohydrolase ppGpp biosynthesis
aroE 1.1.1.282 0.998 shikimate 5-dehydrogenase chorismate biosynthesis from 3-dehydroquinate
aq_957 4.6.1.12 0.998 hypothetical protein methylerythritol phosphate pathway
gap 1.2.1.72 0.992 glyceraldehyde-3-phosphate dehydrogenase pyridoxal 5'-phosphate biosynthesis I
forA2 1.2.7.1 0.939 ferredoxin oxidoreductase subunit alpha reductive TCA cycle II, gluconeogenesis II (Methanobacterium thermoautotrophicum)
purE 5.4.99.18 0.990 phosphoribosylaminoimidazole carboxylase inosine-5'-phosphate biosynthesis I
forB1 1.2.7.3 0.979 ferredoxin oxidoreductase subunit beta reductive TCA cycle II
thiC 4.1.99.17 0.987 thiamine biosynthesis protein ThiC 4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis
gltX none 0.996 glutamyl-tRNA synthetase L-glutamine biosynthesis II (tRNA-dependent)
sucC1 6.2.1.18 0.999 succinyl-CoA ligase subunit beta reductive TCA cycle II
moeB 2.7.7.73 0.998 molybdopterin biosynthesis protein MoeB thiazole biosynthesis II (Bacillus), thiazole biosynthesis I (E. coli)
moeB none 0.998 molybdopterin biosynthesis protein MoeB thiazole biosynthesis I (E. coli)
murC 6.3.2.- 0.991 UDP-N-acetylmuramate-alanine ligase anhydromuropeptides recycling
thiE1 5.3.99.10 0.975 thiamine phosphate synthase thiazole biosynthesis II (Bacillus)


Report Errors or Provide Feedback
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, BIOCYC13A.