Synonyms: plasma thromboplastin antecedent
Factor XI, or plasma thromboplastin antecedent, is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade EC 188.8.131.52. Like many other coagulation factors, it is a serine protease.
Factor XI is produced by the liver and circulates as a homo-dimer in its inactive form. It is activated into factor XIa by thrombin (also known as factor XIIa), and it is also autocatalytic in that respect.
Alternative forms of a factor XI: a factor XIa (summary available)
Unification Links: Wikipedia:Factor_XI
Created 10-Aug-2009 by SRI International
©2015 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493