If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
Locations of Mapped Genes:
|Superclasses:||Biosynthesis → Amino Acids Biosynthesis → Proteinogenic Amino Acids Biosynthesis → L-threonine Biosynthesis|
Pathway Summary from MetaCyc:
The pathway of synthesis of threonine from homoserine is a two-step pathway that converts homoserine to threonine by way of a phosphorylated intermediate.
The final product of this pathway, threonine, serves as a structural constituent of proteins and feeds into the biosynthetic pathway for isoleucine. The enzymes carrying out both steps in this pathway are regulated at the gene level by threonine- and isoleucine-dependent attenuation, as part of attenuation control of an operon that also includes a gene coding for an enzyme in the upstream pathway of homoserine biosynthesis.
Superpathways: isoleucine biosynthesis I
Created this pathway so that threonine biosynthesis could be changed to be a super-pathway of this plus homoserine biosynthesis.
Pathway Evidence Glyph:
This organism is in the expected taxonomic range for this pathway.
Last-Curated 09-May-2008 by SRI International
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