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Caulobacter crescentus CB15 Pathway: threonine biosynthesis from homoserine
Inferred by computational analysis


Pathway diagram: threonine biosynthesis from homoserine

If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.

Locations of Mapped Genes:

Schematic showing all replicons, marked with selected genes

Superclasses: BiosynthesisAmino Acids BiosynthesisProteinogenic Amino Acids BiosynthesisL-threonine Biosynthesis

Pathway Summary from MetaCyc:
The pathway of synthesis of threonine from homoserine is a two-step pathway that converts homoserine to threonine by way of a phosphorylated intermediate.

The final product of this pathway, threonine, serves as a structural constituent of proteins and feeds into the biosynthetic pathway for isoleucine. The enzymes carrying out both steps in this pathway are regulated at the gene level by threonine- and isoleucine-dependent attenuation, as part of attenuation control of an operon that also includes a gene coding for an enzyme in the upstream pathway of homoserine biosynthesis.

Superpathways: isoleucine biosynthesis I

History:
Created this pathway so that threonine biosynthesis could be changed to be a super-pathway of this plus homoserine biosynthesis.

Pathway Evidence Glyph:

Pathway evidence glyph

This organism is in the expected taxonomic range for this pathway.

Key to pathway glyph edge colors:

  An enzyme catalyzing this reaction is present in this organism
  The reaction is unique to this pathway in MetaCyc

Credits:
Last-Curated 09-May-2008 by SRI International


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Page generated by Pathway Tools version 19.5 (software by SRI International) on Fri Apr 29, 2016, biocyc13.