|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Group Translocation → Phosphenolpyruvate (PEP)-Dependent Transport|
|Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Group Translocation → Phosphenolpyruvate (PEP)-Dependent Transport|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 22.214.171.124
Transporters and Genes:
PTS system, nitrogen regulatory IIA component : ptsN
PTS system, N-acetylglucosamine-specific IIABC component : nagE
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: protein-Nπ-phosphohistidine—sugar phosphotransferase
Enzyme Commission Synonyms: glucose permease, PTS permease, phosphotransferase, phosphohistidinoprotein-hexose, enzyme IIl4ac, gene glC proteins, gene bglC RNA formation factors, PEP-dependent phosphotransferase enzyme II, PEP-sugar phosphotransferase enzyme II, phosphoenolpyruvate-sugar phosphotransferase enzyme II, phosphohistidinoprotein-hexose phosphotransferase, phosphohistidinoprotein-hexose phosphoribosyltransferase, phosphoprotein factor-hexose phosophotransferase, protein, specific or class, gene bglC, ribonucleic acid formation factor, gene glC, sucrose phosphotransferase system II, protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase, protein-Npi-phosphohistidine:sugar Npi-phosphotransferase
Enzyme Commission Summary:
Enzyme II of the phosphotransferase system. Comprises a group of related enzymes. The protein substrate is a phosphocarrier protein of low molecular mass (9.5 kDa). The protein is phosphorylated in a reaction catalysed by EC 126.96.36.199, phosphoenolpyruvate—protein phosphotransferase and this acts as the phosphate donor for the above reaction.
The enzyme translocates the sugar it phosphorylates into bacteria. Aldohexoses, and their glycosides and alditols, are phosphorylated on O-6, whereas fructose and sorbose are phosphorylated on O-1. Glycerone and disaccharides are also substrates.
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493