Caulobacter crescentus CB15 Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
lactoylglutathione lyase, putative : CC1315
lactoylglutathione lyase, putative : CC1933

In Pathway: methylglyoxal degradation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: lactoylglutathione lyase

Enzyme Commission Synonyms: methylglyoxalase, aldoketomutase, ketone-aldehyde mutase, glyoxylase I, (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing)

Enzyme Commission Summary:
Also acts on 3-phosphoglycerol-glutathione.

Citations: [Ekwall73, RACKER51]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Ekwall73: Ekwall K, Mannervik B (1973). "The stereochemical configuration of the lactoyl group of S-lactoylglutathionine formed by the action of glyoxalase I from porcine erythrocytes and yeast." Biochim Biophys Acta 297(2);297-9. PMID: 4574550

RACKER51: RACKER E (1951). "The mechanism of action of glyoxalase." J Biol Chem 190(2);685-96. PMID: 14841219

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