|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
In Pathway: methylglyoxal degradation I
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: lactoylglutathione lyase
Enzyme Commission Synonyms: methylglyoxalase, aldoketomutase, ketone-aldehyde mutase, glyoxylase I, (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing)
Enzyme Commission Summary:
Also acts on 3-phosphoglycerol-glutathione.
Ekwall73: Ekwall K, Mannervik B (1973). "The stereochemical configuration of the lactoyl group of S-lactoylglutathionine formed by the action of glyoxalase I from porcine erythrocytes and yeast." Biochim Biophys Acta 297(2);297-9. PMID: 4574550
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493