Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Caulobacter crescentus CB15 Reaction: 2.3.1.174

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.174

Enzymes and Genes:
beta-ketoadipyl-CoA thiolase : pcaF
beta-ketoadipyl CoA thiolase : pcaF

In Pathway: 3-oxoadipate degradation

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 3-oxoadipyl-CoA thiolase

Enzyme Commission Summary:
The enzyme from the bacterium Escherichia coli also has the activity of EC 2.3.1.223, 3-oxo-5,6-didehydrosuberyl-CoA thiolase .

Citations: [Kaschabek02, Gobel02, Teufel10]

Gene-Reaction Schematic: ?

Relationship Links: BRENDA:EC:2.3.1.174 , ENZYME:EC:2.3.1.174 , IUBMB-ExplorEnz:EC:2.3.1.174


References

Gobel02: Gobel M, Kassel-Cati K, Schmidt E, Reineke W (2002). "Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: cloning, characterization, and analysis of sequences encoding 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase." J Bacteriol 184(1);216-23. PMID: 11741863

Kaschabek02: Kaschabek SR, Kuhn B, Muller D, Schmidt E, Reineke W (2002). "Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase." J Bacteriol 184(1);207-15. PMID: 11741862

Teufel10: Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G (2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed." Proc Natl Acad Sci U S A 107(32):14390-5. PMID: 20660314


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Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc14.