Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
twitter

Escherichia coli K-12 substr. MG1655 Compound Class: a prosthetic group

Superclasses: a cofactor

Summary:
A prosthetic group is a term for a compound or ion that is essential for the activity of an enzyme, and is tightly bound to the enzyme.

Child Classes: a biopterin (0), a coenzyme F420 (0), a folate (13), a metal-sulfur cluster (0), a methanofuran (0), a Mo-molybdopterin cofactor (5)

Instances:
(R)-lipoate,
coenzyme A,
molybdopterin


References

Allen14: Allen KD, White RH (2014). "Identification of structurally diverse methanofuran coenzymes in methanococcales that are both N-formylated and N-acetylated." Biochemistry 53(39);6199-210. PMID: 25203397

Bobik87: Bobik TA, Donnelly MI, Rinehart KL, Wolfe RS (1987). "Structure of a methanofuran derivative found in cell extracts of Methanosarcina barkeri." Arch Biochem Biophys 254(2);430-6. PMID: 2883935

Cheeseman72: Cheeseman P, Toms-Wood A, Wolfe RS (1972). "Isolation and properties of a fluorescent compound, factor 420 , from Methanobacterium strain M.o.H." J Bacteriol 112(1);527-31. PMID: 5079072

Chistoserdova98: Chistoserdova L, Vorholt JA, Thauer RK, Lidstrom ME (1998). "C1 transfer enzymes and coenzymes linking methylotrophic bacteria and methanogenic Archaea." Science 281(5373);99-102. PMID: 9651254

Choi01: Choi KP, Bair TB, Bae YM, Daniels L (2001). "Use of transposon Tn5367 mutagenesis and a nitroimidazopyran-based selection system to demonstrate a requirement for fbiA and fbiB in coenzyme F(420) biosynthesis by Mycobacterium bovis BCG." J Bacteriol 183(24);7058-66. PMID: 11717263

Eirich78: Eirich LD, Vogels GD, Wolfe RS (1978). "Proposed structure for coenzyme F420 from Methanobacterium." Biochemistry 17(22);4583-93. PMID: 728375

Eisenreich92: Eisenreich W, Bacher A (1992). "Biosynthesis of methanofuran in Methanobacterium thermoautotrophicum." J Biol Chem 267(25);17574-80. PMID: 1517208

Graham02a: Graham DE, White RH (2002). "Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics." Nat Prod Rep 19(2);133-47. PMID: 12013276

Graupner03: Graupner M, White RH (2003). "Methanococcus jannaschii coenzyme F420 analogs contain a terminal alpha-linked glutamate." J Bacteriol 185(15);4662-5. PMID: 12867481

Hanson02: Hanson AD, Gregory JF (2002). "Synthesis and turnover of folates in plants." Curr Opin Plant Biol 5(3);244-9. PMID: 11960743

Jabrin03: Jabrin S, Ravanel S, Gambonnet B, Douce R, Rebeille F (2003). "One-carbon metabolism in plants. Regulation of tetrahydrofolate synthesis during germination and seedling development." Plant Physiol 131(3);1431-9. PMID: 12644692

Li03: Li H, Xu H, Graham DE, White RH (2003). "Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses." Proc Natl Acad Sci U S A 100(17);9785-90. PMID: 12909715

Lucock00: Lucock M (2000). "Folic acid: nutritional biochemistry, molecular biology, and role in disease processes." Mol Genet Metab 71(1-2);121-38. PMID: 11001804

Miller14: Miller D, Wang Y, Xu H, Harich K, White RH (2014). "Biosynthesis of the 5-(Aminomethyl)-3-furanmethanol moiety of methanofuran." Biochemistry 53(28);4635-47. PMID: 24977328

Pomper01: Pomper BK, Vorholt JA (2001). "Characterization of the formyltransferase from Methylobacterium extorquens AM1." Eur J Biochem 268(17);4769-75. PMID: 11532013

White88a: White RH (1988). "Structural diversity among methanofurans from different methanogenic bacteria." J Bacteriol 170(10);4594-7. PMID: 3170480


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon Feb 8, 2016, biocyc13.