Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store

Escherichia coli K-12 substr. MG1655 Compound Class: D-galacturonate

Synonyms: galacturonate, D-galaturonate, galaturonate, D-galacturonic acid, D-galactopyranuronic acid

Superclasses: all carbohydratesa carbohydratea glycan
an acidall carboxy acidsa carboxylatea monocarboxylatea uronatea hexuronategalacturonate

D-galacturonate is a carboxylic acid that can form a ring structure, as shown for α-D-galacturonate and β-D-galacturonate [Richard09].

Glycan icon:

D-galacturonate compound structure

Chemical Formula: C6H9O7

Child Classes: D-galactopyranuronate (1)


Molecular Weight: 193.13 Daltons

Unification Links: CAS:685-73-4, ChEBI:75525, HMDB:HMDB02545, IAF1260:34649, KEGG:C00333, PubChem:46173511

Standard Gibbs Free Energy of Formation (ΔfG in kcal/mol): -258.9 [Forsythe97]

Reactions known to produce the compound:

Not in pathways:
a carboxylic ester + H2O → an alcohol + a carboxylate + H+
an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+
an acyl phosphate + H2O → a carboxylate + phosphate + H+
an acyl-CoA + H2O → a carboxylate + coenzyme A + H+
a 1-acyl 2-lyso-phosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+

In Reactions of unknown directionality:

Not in pathways:
a 2-acyl 1-lyso-phosphatidylcholine + H2O = a carboxylate + sn-glycero-3-phosphocholine + H+
an aldehyde[periplasm] + FAD[periplasm] + H2O[periplasm] = a carboxylate[periplasm] + FADH2[periplasm]

In Transport reactions:
D-galacturonate[periplasm] + H+[periplasm]D-galacturonate[cytosol] + H+[cytosol]

Enzymes activated by D-galacturonate, sorted by the type of activation, are:

Activator (Mechanism unknown) of: D-mannonate dehydratase [RobertBaudouy73]

In Growth Media: PMA carbon source test + D-galacturonate


Forsythe97: Forsythe RG, Karp PD, Mavrovouniotis ML (1997). "Estimation of Equilibrium Constants Using Automated Group Contribution Methods." CABIOS 13(5):537-543.

Richard09: Richard P, Hilditch S (2009). "D-galacturonic acid catabolism in microorganisms and its biotechnological relevance." Appl Microbiol Biotechnol 82(4);597-604. PMID: 19159926

RobertBaudouy73: Robert-Baudouy JM, Stoeber FR (1973). "[Purification and properties of D-mannonate hydrolyase from Escherichia coli K12]." Biochim Biophys Acta 1973;309(2);473-85. PMID: 4581499

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sat Apr 30, 2016, biocyc14.