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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Compound Class: D-galacturonate

Synonyms: galacturonate, D-galaturonate, galaturonate, D-galacturonic acid, D-galactopyranuronic acid

Superclasses: all carbohydrates a carbohydrate a glycan
an acid all carboxy acids a carboxylate galacturonate

Summary:
D-galacturonate is a carboxylic acid that can form a ring structure, as shown for α-D-galacturonate and β-D-galacturonate [Richard09].

Chemical Formula: C6H9O7

Child Classes: D-galactopyranuronate (1)

Instances:
aldehydo-D-galacturonate

Molecular Weight: 193.13 Daltons

Unification Links: CAS:685-73-4 , ChEBI:75525 , HMDB:HMDB02545 , IAF1260:34649 , KEGG:C00333 , PubChem:46173511

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -258.9 [Forsythe97]

Reactions known to produce the compound:

Not in pathways:
a carboxylic ester + H2O → an alcohol + a carboxylate + H+
an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+
an acyl phosphate + H2O → a carboxylate + phosphate + H+
an acyl-CoA + H2O → a carboxylate + coenzyme A + H+
a 1-lysophosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+

In Reactions of unknown directionality:

Not in pathways:
an aldehyde[periplasmic space] + FAD[periplasmic space] + H2O[periplasmic space] = a carboxylate[periplasmic space] + FADH2[periplasmic space]

In Transport reactions:
D-galacturonate[periplasmic space] + H+[periplasmic space]D-galacturonate[cytosol] + H+[cytosol]

Enzymes activated by D-galacturonate, sorted by the type of activation, are:

Activator (Mechanism unknown) of: D-mannonate dehydratase [RobertBaudouy73]

In Growth Media: PMA carbon source test + D-galacturonate


References

Forsythe97: Forsythe RG, Karp PD, Mavrovouniotis ML (1997). "Estimation of Equilibrium Constants Using Automated Group Contribution Methods." CABIOS 13(5):537-543.

Richard09: Richard P, Hilditch S (2009). "D-galacturonic acid catabolism in microorganisms and its biotechnological relevance." Appl Microbiol Biotechnol 82(4);597-604. PMID: 19159926

RobertBaudouy73: Robert-Baudouy JM, Stoeber FR (1973). "[Purification and properties of D-mannonate hydrolyase from Escherichia coli K12]." Biochim Biophys Acta 1973;309(2);473-85. PMID: 4581499


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.