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Escherichia coli K-12 substr. MG1655 EC 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Parent Class: EC-Numbers1 -- Oxidoreductases1.1 -- Acting on the CH-OH group of donors

Instances:
1.1.1.1 -- alcohol dehydrogenase,
1.1.1.2 -- alcohol dehydrogenase (NADP+),
1.1.1.3 -- homoserine dehydrogenase,
1.1.1.6 -- glycerol dehydrogenase,
1.1.1.17 -- mannitol-1-phosphate 5-dehydrogenase,
1.1.1.22 -- UDP-glucose 6-dehydrogenase,
1.1.1.23 -- histidinol dehydrogenase,
1.1.1.25 -- shikimate dehydrogenase,
1.1.1.28 -- D-lactate dehydrogenase,
1.1.1.35 -- 3-hydroxyacyl-CoA dehydrogenase,
1.1.1.37 -- malate dehydrogenase,
1.1.1.38 -- malate dehydrogenase (oxaloacetate-decarboxylating),
1.1.1.39 -- malate dehydrogenase (decarboxylating),
1.1.1.40 -- malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+),
1.1.1.42 -- isocitrate dehydrogenase (NADP+),
1.1.1.44 -- phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating),
1.1.1.49 -- glucose-6-phosphate dehydrogenase (NADP+),
1.1.1.57 -- fructuronate reductase,
1.1.1.58 -- tagaturonate reductase,
1.1.1.60 -- 2-hydroxy-3-oxopropionate reductase,
1.1.1.61 -- 4-hydroxybutyrate dehydrogenase,
1.1.1.69 -- gluconate 5-dehydrogenase,
1.1.1.75 -- (R)-aminopropanol dehydrogenase,
1.1.1.77 -- lactaldehyde reductase,
1.1.1.79 -- glyoxylate reductase (NADP+),
1.1.1.83 -- D-malate dehydrogenase (decarboxylating),
1.1.1.85 -- 3-isopropylmalate dehydrogenase,
1.1.1.86 -- ketol-acid reductoisomerase,
1.1.1.91 -- aryl-alcohol dehydrogenase (NADP+),
1.1.1.93 -- tartrate dehydrogenase,
1.1.1.94 -- glycerol-3-phosphate dehydrogenase [NAD(P)+],
1.1.1.95 -- phosphoglycerate dehydrogenase,
1.1.1.100 -- 3-oxoacyl-[acyl-carrier-protein] reductase,
1.1.1.103 -- L-threonine 3-dehydrogenase,
1.1.1.125 -- 2-deoxy-D-gluconate 3-dehydrogenase,
1.1.1.127 -- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase,
1.1.1.130 -- 3-dehydro-L-gulonate 2-dehydrogenase,
1.1.1.133 -- dTDP-4-dehydrorhamnose reductase,
1.1.1.140 -- sorbitol-6-phosphate 2-dehydrogenase,
1.1.1.154 -- ureidoglycolate dehydrogenase,
1.1.1.159 -- 7α-hydroxysteroid dehydrogenase,
1.1.1.168 -- 2-dehydropantolactone reductase (Re-specific),
1.1.1.169 -- 2-dehydropantoate 2-reductase,
1.1.1.193 -- 5-amino-6-(5-phosphoribosylamino)uracil reductase,
1.1.1.205 -- IMP dehydrogenase,
1.1.1.211 -- long-chain-3-hydroxyacyl-CoA dehydrogenase,
1.1.1.214 -- 2-dehydropantolactone reductase (Si-specific),
1.1.1.215 -- gluconate 2-dehydrogenase,
1.1.1.251 -- galactitol-1-phosphate 5-dehydrogenase,
1.1.1.262 -- 4-hydroxythreonine-4-phosphate dehydrogenase,
1.1.1.264 -- L-idonate 5-dehydrogenase,
1.1.1.267 -- 1-deoxy-D-xylulose-5-phosphate reductoisomerase,
1.1.1.271 -- GDP-L-fucose synthase,
1.1.1.274 -- 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming),
1.1.1.276 -- serine 3-dehydrogenase (NADP+),
1.1.1.282 -- quinate/shikimate dehydrogenase,
1.1.1.283 -- methylglyoxal reductase (NADPH),
1.1.1.284 -- S-(hydroxymethyl)glutathione dehydrogenase,
1.1.1.290 -- 4-phosphoerythronate dehydrogenase,
1.1.1.298 -- 3-hydroxypropionate dehydrogenase (NADP+),
1.1.1.305 -- UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating),
1.1.1.336 -- UDP-N-acetyl-D-mannosamine dehydrogenase,
1.1.1.346 -- 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming),
1.1.1.350 -- ureidoglycolate dehydrogenase (NAD+),
1.1.1.358 -- 2-dehydropantolactone reductase,
1.1.1.373 -- sulfolactaldehyde 3-reductase,
1.1.1.381 -- 3-hydroxy acid dehydrogenase

Unofficial Reactions:
acetoin + NADP+ = diacetyl + NADPH + H+,
(R)-2-hydroxyglutarate + NAD+ ↔ 2-oxoglutarate + NADH + H+,
11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD+,
(R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+,
(S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+,
(S)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+,
2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+,
a uridine in tRNA + NADPH + H+ → a 5,6-dihydrouridine in tRNA + NADP+,
ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP+ = ethyl-2-methylacetoacetate + NADPH + H+,
D-glycerate + NADP+ ← hydroxypyruvate + NADPH + H+,
acetol + NADP+ ↔ methylglyoxal + NADPH + H+,
methylglyoxal + NADH + H+ = acetol + NAD+,
aldehydo-L-galactonate + NAD+ → D-tagaturonate + NADH + H+,
D-glycerate + NAD+ ↔ tartronate semialdehyde + NADH + H+,
sn-glycerol 3-phosphate + NADP+ ← L-glyceraldehyde 3-phosphate + NADPH + H+,
1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+,
2-keto-L-gulonate + NADPH + H+ → L-idonate + NADP+,
isobutanol + NADP+ = isobutanal + NADPH + H+,
5-dehydro-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+,
2-keto-D-gluconate + NADPH + H+ = L-idonate + NADP+,
dTDP-β-L-rhamnose + NAD+ ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NADH + H+

Enzymes and Genes:
dTDP-L-rhamnose synthetase: rfbC, rfbD
NADP+-dependent aldehyde reductase: yghA
tartronate semialdehyde reductase 2: glxR
tartronate semialdehyde reductase: garR
L-galactonate oxidoreductase: lgoD
methylglyoxal reductase (NADH-dependent): ydjG
methylglyoxal reductase: yeaE
methylglyoxal reductase [multifunctional]: dkgB
L-glyceraldehyde 3-phosphate reductase: yghZ
glyoxylate reductase / hydroxypyruvate reductase: ghrA
glyoxylate reductase [multifunctional]: ghrB
methylglyoxal reductase [multifunctional]: dkgA
tRNA-dihydrouridine synthase C: dusC
tRNA-dihydrouridine synthase B: dusB
tRNA-dihydrouridine synthase A: dusA
NADPH-dependent aldehyde reductase: yqhD
aldehyde reductase, NADPH-dependent: yahK
aldehyde reductase, NADPH-dependent: ahr
NADP+-dependent aldehyde reductase: ybbO
predicted 2-keto-3-deoxy-D-gluconate dehydrogenase: kduD
(S)-2-hydroxyglutarate reductase [multifunctional]: serA
predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain: yohF


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun Feb 14, 2016, biocyc14.