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discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 EC 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.1 -- Acting on the CH-OH group of donors

Instances:
1.1.1.1 -- alcohol dehydrogenase ,
1.1.1.2 -- alcohol dehydrogenase (NADP+) ,
1.1.1.3 -- homoserine dehydrogenase ,
1.1.1.6 -- glycerol dehydrogenase ,
1.1.1.17 -- mannitol-1-phosphate 5-dehydrogenase ,
1.1.1.22 -- UDP-glucose 6-dehydrogenase ,
1.1.1.25 -- shikimate dehydrogenase ,
1.1.1.28 -- D-lactate dehydrogenase ,
1.1.1.35 -- 3-hydroxyacyl-CoA dehydrogenase ,
1.1.1.37 -- malate dehydrogenase ,
1.1.1.38 -- malate dehydrogenase (oxaloacetate-decarboxylating) ,
1.1.1.39 -- malate dehydrogenase (decarboxylating) ,
1.1.1.40 -- malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) ,
1.1.1.42 -- isocitrate dehydrogenase (NADP+) ,
1.1.1.44 -- phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) ,
1.1.1.49 -- glucose-6-phosphate dehydrogenase (NADP+) ,
1.1.1.57 -- fructuronate reductase ,
1.1.1.58 -- tagaturonate reductase ,
1.1.1.60 -- 2-hydroxy-3-oxopropionate reductase ,
1.1.1.61 -- 4-hydroxybutyrate dehydrogenase ,
1.1.1.69 -- gluconate 5-dehydrogenase ,
1.1.1.75 -- (R)-aminopropanol dehydrogenase ,
1.1.1.77 -- lactaldehyde reductase ,
1.1.1.79 -- glyoxylate reductase (NADP+) ,
1.1.1.83 -- D-malate dehydrogenase (decarboxylating) ,
1.1.1.86 -- ketol-acid reductoisomerase ,
1.1.1.91 -- aryl-alcohol dehydrogenase (NADP+) ,
1.1.1.93 -- tartrate dehydrogenase ,
1.1.1.94 -- glycerol-3-phosphate dehydrogenase [NAD(P)+] ,
1.1.1.95 -- phosphoglycerate dehydrogenase ,
1.1.1.100 -- 3-oxoacyl-[acyl-carrier-protein] reductase ,
1.1.1.103 -- L-threonine 3-dehydrogenase ,
1.1.1.125 -- 2-deoxy-D-gluconate 3-dehydrogenase ,
1.1.1.127 -- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase ,
1.1.1.130 -- 3-dehydro-L-gulonate 2-dehydrogenase ,
1.1.1.133 -- dTDP-4-dehydrorhamnose reductase ,
1.1.1.140 -- sorbitol-6-phosphate 2-dehydrogenase ,
1.1.1.154 -- ureidoglycolate dehydrogenase ,
1.1.1.159 -- 7α-hydroxysteroid dehydrogenase ,
1.1.1.169 -- 2-dehydropantoate 2-reductase ,
1.1.1.193 -- 5-amino-6-(5-phosphoribosylamino)uracil reductase ,
1.1.1.205 -- IMP dehydrogenase ,
1.1.1.211 -- long-chain-3-hydroxyacyl-CoA dehydrogenase ,
1.1.1.215 -- gluconate 2-dehydrogenase ,
1.1.1.264 -- L-idonate 5-dehydrogenase ,
1.1.1.267 -- 1-deoxy-D-xylulose-5-phosphate reductoisomerase ,
1.1.1.271 -- GDP-L-fucose synthase ,
1.1.1.274 -- 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) ,
1.1.1.276 -- serine 3-dehydrogenase ,
1.1.1.282 -- quinate/shikimate dehydrogenase ,
1.1.1.283 -- methylglyoxal reductase (NADPH) ,
1.1.1.284 -- S-(hydroxymethyl)glutathione dehydrogenase ,
1.1.1.290 -- 4-phosphoerythronate dehydrogenase ,
1.1.1.298 -- 3-hydroxypropionate dehydrogenase (NADP+) ,
1.1.1.305 -- UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) ,
1.1.1.336 -- UDP-N-acetyl-D-mannosamine dehydrogenase ,
1.1.1.346 -- 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) ,
1.1.1.350 -- ureidoglycolate dehydrogenase (NAD+) ,
1.1.1.351 -- phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating] ,
1.1.1.358 -- 2-dehydropantolactone reductase ,
1.1.1.373 -- sulfolactaldehyde 3-reductase

Unofficial Reactions:
acetoin + NADP+ = diacetyl + NADPH + H+ ,
galactitol 1-phosphate + NAD+ ↔ D-tagatofuranose 6-phosphate + NADH + H+ ,
2,5-didehydro-D-gluconate + NAD(P)H + H+ = 2-keto-L-gulonate + NAD(P)+ ,
11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD+ ,
(R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+ ,
(S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+ ,
2-hydroxyglutarate + NAD+ ↔ 2-oxoglutarate + NADH + H+ ,
a 5,6-dihydrouridine in tRNA + NADP+ ← a uridine in tRNA + NADPH + H+ ,
ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP+ = ethyl-2-methylacetoacetate + NADPH + H+ ,
D-glycerate + NADP+ ← hydroxypyruvate + NADPH + H+ ,
acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
methylglyoxal + NADH + H+ = acetol + NAD+ ,
D-glycerate + NAD+ ↔ tartronate semialdehyde + NADH + H+ ,
sn-glycerol 3-phosphate + NADP+ ← L-glyceraldehyde 3-phosphate + NADPH + H+ ,
1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
L-idonate + NADP+ ← 2-keto-L-gulonate + NADPH + H+ ,
isobutanol + NADP+ = isobutanal + NADPH + H+ ,
5-dehydro-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
2-keto-D-gluconate + NADPH + H+ = L-idonate + NADP+ ,
dTDP-β-L-rhamnose + NAD+ ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NADH + H+

Enzymes and Genes:
dTDP-L-rhamnose synthetase : rfbC , rfbD
NADP+-dependent aldehyde reductase : yghA
tartronate semialdehyde reductase 2 : glxR
tartronate semialdehyde reductase : garR
methylglyoxal reductase (NADH-dependent) : ydjG
methylglyoxal reductase : yeaE
methylglyoxal reductase [multifunctional] : dkgB
L-glyceraldehyde 3-phosphate reductase : yghZ
glyoxylate reductase / hydroxypyruvate reductase : ghrA
glyoxylate reductase [multifunctional] : ghrB
methylglyoxal reductase [multifunctional] : dkgA
tRNA-dihydrouridine synthase C : dusC
tRNA-dihydrouridine synthase B : dusB
tRNA-dihydrouridine synthase A : dusA
D-3-phosphoglycerate dehydrogenase / α-ketoglutarate reductase : serA
NADPH-dependent aldehyde reductase : yqhD
aldehyde reductase, NADPH-dependent : yahK
aldehyde reductase, NADPH-dependent : ahr
NADP+-dependent aldehyde reductase : ybbO
predicted 2-keto-3-deoxy-D-gluconate dehydrogenase : kduD
galactitol-1-phosphate dehydrogenase : gatD
predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain : yohF


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, BIOCYC13B.