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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
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Escherichia coli K-12 substr. MG1655 EC 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Parent Class: EC-Numbers 1 -- Oxidoreductases 1.1 -- Acting on the CH-OH group of donors

Instances:
1.1.1.1 -- alcohol dehydrogenase ,
1.1.1.2 -- alcohol dehydrogenase (NADP+) ,
1.1.1.3 -- homoserine dehydrogenase ,
1.1.1.6 -- glycerol dehydrogenase ,
1.1.1.17 -- mannitol-1-phosphate 5-dehydrogenase ,
1.1.1.22 -- UDP-glucose 6-dehydrogenase ,
1.1.1.25 -- shikimate dehydrogenase ,
1.1.1.28 -- D-lactate dehydrogenase ,
1.1.1.35 -- 3-hydroxyacyl-CoA dehydrogenase ,
1.1.1.37 -- malate dehydrogenase ,
1.1.1.38 -- malate dehydrogenase (oxaloacetate-decarboxylating) ,
1.1.1.39 -- malate dehydrogenase (decarboxylating) ,
1.1.1.40 -- malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) ,
1.1.1.42 -- isocitrate dehydrogenase (NADP+) ,
1.1.1.44 -- phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) ,
1.1.1.49 -- glucose-6-phosphate dehydrogenase (NADP+) ,
1.1.1.57 -- fructuronate reductase ,
1.1.1.58 -- tagaturonate reductase ,
1.1.1.60 -- 2-hydroxy-3-oxopropionate reductase ,
1.1.1.61 -- 4-hydroxybutyrate dehydrogenase ,
1.1.1.69 -- gluconate 5-dehydrogenase ,
1.1.1.75 -- (R)-aminopropanol dehydrogenase ,
1.1.1.77 -- lactaldehyde reductase ,
1.1.1.79 -- glyoxylate reductase (NADP+) ,
1.1.1.83 -- D-malate dehydrogenase (decarboxylating) ,
1.1.1.86 -- ketol-acid reductoisomerase ,
1.1.1.91 -- aryl-alcohol dehydrogenase (NADP+) ,
1.1.1.93 -- tartrate dehydrogenase ,
1.1.1.94 -- glycerol-3-phosphate dehydrogenase [NAD(P)+] ,
1.1.1.95 -- phosphoglycerate dehydrogenase ,
1.1.1.100 -- 3-oxoacyl-[acyl-carrier-protein] reductase ,
1.1.1.103 -- L-threonine 3-dehydrogenase ,
1.1.1.125 -- 2-deoxy-D-gluconate 3-dehydrogenase ,
1.1.1.127 -- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase ,
1.1.1.130 -- 3-dehydro-L-gulonate 2-dehydrogenase ,
1.1.1.133 -- dTDP-4-dehydrorhamnose reductase ,
1.1.1.140 -- sorbitol-6-phosphate 2-dehydrogenase ,
1.1.1.154 -- ureidoglycolate dehydrogenase ,
1.1.1.159 -- 7α-hydroxysteroid dehydrogenase ,
1.1.1.169 -- 2-dehydropantoate 2-reductase ,
1.1.1.193 -- 5-amino-6-(5-phosphoribosylamino)uracil reductase ,
1.1.1.205 -- IMP dehydrogenase ,
1.1.1.211 -- long-chain-3-hydroxyacyl-CoA dehydrogenase ,
1.1.1.215 -- gluconate 2-dehydrogenase ,
1.1.1.264 -- L-idonate 5-dehydrogenase ,
1.1.1.267 -- 1-deoxy-D-xylulose-5-phosphate reductoisomerase ,
1.1.1.271 -- GDP-L-fucose synthase ,
1.1.1.274 -- 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) ,
1.1.1.276 -- serine 3-dehydrogenase ,
1.1.1.282 -- quinate/shikimate dehydrogenase ,
1.1.1.283 -- methylglyoxal reductase (NADPH) ,
1.1.1.284 -- S-(hydroxymethyl)glutathione dehydrogenase ,
1.1.1.290 -- 4-phosphoerythronate dehydrogenase ,
1.1.1.298 -- 3-hydroxypropionate dehydrogenase (NADP+) ,
1.1.1.305 -- UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) ,
1.1.1.336 -- UDP-N-acetyl-D-mannosamine dehydrogenase ,
1.1.1.346 -- 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) ,
1.1.1.350 -- ureidoglycolate dehydrogenase (NAD+) ,
1.1.1.351 -- phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating] ,
1.1.1.358 -- 2-dehydropantolactone reductase ,
1.1.1.373 -- sulfolactaldehyde 3-reductase

Unofficial Reactions:
acetoin + NADP+ = diacetyl + NADPH + H+ ,
galactitol 1-phosphate + NAD+ ↔ D-tagatofuranose 6-phosphate + NADH + H+ ,
2,5-didehydro-D-gluconate + NAD(P)H + H+ = 2-keto-L-gulonate + NAD(P)+ ,
11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD+ ,
(R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+ ,
(S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+ ,
2-hydroxyglutarate + NAD+ ↔ 2-oxoglutarate + NADH + H+ ,
a 5,6-dihydrouridine in tRNA + NADP+ ← a uridine in tRNA + NADPH + H+ ,
ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP+ = ethyl-2-methylacetoacetate + NADPH + H+ ,
D-glycerate + NADP+ ← hydroxypyruvate + NADPH + H+ ,
acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
methylglyoxal + NADH + H+ = acetol + NAD+ ,
D-glycerate + NAD+ ↔ tartronate semialdehyde + NADH + H+ ,
sn-glycerol 3-phosphate + NADP+ ← L-glyceraldehyde 3-phosphate + NADPH + H+ ,
1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
L-idonate + NADP+ ← 2-keto-L-gulonate + NADPH + H+ ,
isobutanol + NADP+ = isobutanal + NADPH + H+ ,
5-dehydro-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
2-keto-D-gluconate + NADPH + H+ = L-idonate + NADP+ ,
dTDP-β-L-rhamnose + NAD+ ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NADH + H+

Enzymes and Genes:
dTDP-L-rhamnose synthetase : rfbC , rfbD
NADP+-dependent aldehyde reductase : yghA
tartronate semialdehyde reductase 2 : glxR
tartronate semialdehyde reductase : garR
methylglyoxal reductase (NADH-dependent) : ydjG
methylglyoxal reductase : yeaE
methylglyoxal reductase [multifunctional] : dkgB
L-glyceraldehyde 3-phosphate reductase : yghZ
glyoxylate reductase / hydroxypyruvate reductase : ghrA
glyoxylate reductase [multifunctional] : ghrB
methylglyoxal reductase [multifunctional] : dkgA
tRNA-dihydrouridine synthase C : dusC
tRNA-dihydrouridine synthase B : dusB
tRNA-dihydrouridine synthase A : dusA
D-3-phosphoglycerate dehydrogenase / α-ketoglutarate reductase : serA
NADPH-dependent aldehyde reductase : yqhD
aldehyde reductase, NADPH-dependent : yahK
aldehyde reductase, NADPH-dependent : ahr
NADP+-dependent aldehyde reductase : ybbO
predicted 2-keto-3-deoxy-D-gluconate dehydrogenase : kduD
galactitol-1-phosphate dehydrogenase : gatD
predicted oxidoreductase with NAD(P)-binding Rossmann-fold domain : yohF


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC13B.