Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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Escherichia coli K-12 substr. MG1655 EC 6.3.2 -- Acid--amino-acid ligases (peptide synthases)

Parent Class: EC-Numbers 6 -- Ligases 6.3 -- Forming carbon-nitrogen bonds

Instances:
6.3.2.1 -- pantoate—β-alanine ligase (AMP-forming) ,
6.3.2.2 -- glutamate—cysteine ligase ,
6.3.2.3 -- glutathione synthase ,
6.3.2.4 -- D-alanine—D-alanine ligase ,
6.3.2.5 -- phosphopantothenate—cysteine ligase ,
6.3.2.6 -- phosphoribosylaminoimidazolesuccinocarboxamide synthase ,
6.3.2.8 -- UDP-N-acetylmuramate—L-alanine ligase ,
6.3.2.9 -- UDP-N-acetylmuramoyl-L-alanine—D-glutamate ligase ,
6.3.2.10 -- UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase ,
6.3.2.12 -- dihydrofolate synthase ,
6.3.2.13 -- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase ,
6.3.2.14 -- enterobactin synthase ,
6.3.2.17 -- tetrahydrofolate synthase

Unofficial Reactions:
UDP-N-α-D-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
a [protein] C-terminal L-glutamate + L-glutamate + ATP → a [protein] with C-terminal α-L-glutamate-α-L-glutamate + ADP + phosphate + H+ ,
a [protein chain elongation factor EF-P]-L-lysine34 + D-β-lysine + ATP → [a protein chain elongation factor EF-P]-β-L-lysyl-L-lysine34 + AMP + diphosphate + H+ ,
UDP-N-α-D-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + ADP + phosphate + H+

Enzymes and Genes:
EF-P-lysine lysyltransferase : epmA
ribosomal protein S6 modification protein : rimK
UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminoheptanedioate-D-alanine ligase [multifunctional] : mpl


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc12.