Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0000724 - double-strand break repair via homologous recombination

Synonyms: GO:0016924, HDR, homologous recombinational repair, homology-directed repair, HRR, Rad51-dependent recombinational repair, Rhp51-dependent recombinational repair

Definition: The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.

Parent Classes:
GO:0000725 - recombinational repair ,
GO:0006302 - double-strand break repair

GO:0043150 - DNA synthesis involved in double-strand break repair via homologous recombination (1)

Term Members:
RecB ,
RecC ,
RecD ,
protein used in recombination and DNA repair (recN)

Unification Links: GO:0000724 , Reactome:73888 , Reactome:1253051 , Reactome:1279987 , Reactome:1298880 , Reactome:1326557 , Reactome:1352669 , Reactome:1372885 , Reactome:1392905 , Reactome:1417375 , Reactome:1450476 , Reactome:1470990 , Reactome:1483018 , Reactome:1496785 , Reactome:1514175 , Reactome:1521015 , Reactome:1526749 , Reactome:1532480 , Reactome:1536017 , Reactome:1539266

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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