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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0003700 - transcription factor activity, sequence-specific DNA binding

Synonyms: GO:0000130, sequence-specific DNA binding transcription factor activity

Definition: Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.

Parent Classes:
GO:0001071 - nucleic acid binding transcription factor activity

Child Classes:
GO:0001073 - transcription antitermination factor activity, DNA binding (2),
GO:0001130 - bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding (20),
GO:0001199 - transcription factor activity, metal ion regulated sequence-specific DNA binding (1)

Term Members:
predicted structural protein, ethanolamine utilization microcompartment (eutK),
predicted DNA-binding transcriptional regulator (yfaX),
MhpR transcriptional activator,
CP4-6 prophage; predicted DNA-binding transcriptional regulator (yagI),
KpLE2 phage-like element; predicted DNA-binding transcriptional regulator (yjhI),
YiaJ DNA-binding transcriptional repressor,
IclR transcriptional repressor,
YedW DNA-binding response regulator in two-component system with YedV,
YqjI DNA-binding transcriptional repressor,
SutR DNA-binding transcriptional dual regulator,
predicted DNA-binding transcriptional regulator (ybiH),
MraZ DNA-binding transcriptional repressor,
KpLE2 phage-like element; predicted DNA-binding transcriptional regulator (yjhU),
OxyR DNA-binding transcriptional dual regulator,
fused PutA transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase,
BetI DNA-binding transcriptional repressor,
NsrR,
NikR DNA-binding transcriptional repressor, Ni-binding,
PerR transcriptional regulator,
Cbl DNA-binding transcriptional activator,
YqhC DNA-binding transcriptional activator,
predicted DNA-binding transcriptional regulator LYSR-type (ybdO),
fused predicted DNA-binding transcriptional regulator and predicted amino transferase (ydcR),
predicted DNA-binding transcriptional regulator (ydjF),
predicted DNA-binding transcriptional regulator, LysR-type (yahB),
DLP12 prophage; predicted DNA-binding transcriptional regulator (ybcM),
predicted DNA-binding transcriptional regulator, LacI type (ycjW),
predicted DNA-binding transcriptional regulator (ykgA),
predicted DNA-binding transcriptional regulator (ynfL),
predicted DNA-binding transcriptional regulator (ydiP),
predicted ARAC-type regulatory protein (ypdC),
RclR DNA-binding transcriptional activator,
PgrR DNA-binding transcriptional repressor,
predicted DNA-binding transcriptional regulator, LysR-type (yneJ),
predicted DNA-binding transcriptional regulator (ygaV),
YdcI DNA-binding transcriptional repressor,
predicted DNA-binding transcriptional regulator (yeeY),
NimR DNA-binding transcriptional repressor,
predicted transcriptional regulator (yneL),
YdeO DNA-binding transcriptional dual regulator,
DNA-binding transcriptional regulator (yciT),
putative transcriptional regulator LYSR-type (ycaN),
quorum sensing transcriptional regulator of LYSR-type (aaeR),
predicted DNA-binding transcriptional regulator LYSR-type (yhaJ),
predicted DNA-binding transcriptional regulator (ybhD),
predicted DNA-binding transcriptional regulator, DEOR-type (ygbI),
CP4-57 prophage; predicted DNA-binding transcriptional regulator (yfjR),
predicted DNA-binding transcriptional regulator LYSR-type (ygfI),
YebK DNA-binding transcriptional repressor,
DsdC DNA-binding transcriptional dual regulator,
predicted DNA-binding transcriptional regulator (frlR),
predicted DNA-binding transcriptional regulator (lgoR),
fused predicted DNA-binding transcriptional regulator and predicted aminotransferase (yjiR),
HypT transcriptional dual regulator,
KpLE2 phage-like element; predicted DNA-binding transcriptional regulator (sgcR),
IdnR transcriptional regulator,
UxuR DNA-binding transcriptional repressor,
predicted DNA-binding transcriptional regulator (yfhH),
predicted DNA-binding transcriptional regulator, LysR-type (yiaU),
predicted DNA-binding transcriptional regulator (yhjC),
GadX DNA-binding transcriptional dual regulator,
CsiR DNA-binding transcriptional repressor,
ArsR,
NorR DNA-binding transcriptional dual regulator,
LrhA DNA-binding transcriptional dual regulator,
putative ARAC-type regulatory protein (eutR),
predicted DNA-binding transcriptional regulator LYSR-type (yfiE),
predicted DNA-binding transcriptional regulator (yijO),
predicted DNA-binding transcriptional regulator (yihW),
predicted transcriptional regulator (yieP),
putative transcriptional regulator LysR-type (yidZ),
predicted DNA-binding transcriptional regulator (dgoR),
predicted DNA-binding transcriptional regulator (yidP),
predicted DNA-binding transcriptional regulator (yidL),
predicted DNA-binding transcriptional regulator, LYSR-type (ybeF),
predicted DNA-binding transcriptional regulator LYSR-type (yafC),
MarR transcriptional repressor,
CynR DNA-binding transcriptional dual regulator,
GalS DNA-binding transcriptional dual regulator,
RNA polymerase, sigma 54 (sigma N) factor (rpoN),
RNA polymerase, sigma 19 factor (fecI),
MalI DNA-binding transcriptional repressor,
ChbR DNA-binding transcriptional dual regulator,
GutR DNA-binding transcriptional repressor (srlR),
EnvY DNA-binding transcriptional activator,
LeuO DNA-binding transcriptional dual regulator,
IscR DNA-binding transcriptional dual regulator,
RNA polymerase, sigma 24 (sigma E) factor (rpoE),
RNA polymerase, sigma 32 (sigma H) factor (rpoH),
transcription termination/antitermination L factor (nusA),
NagC DNA-binding transcriptional dual regulator,
RNA polymerase, sigma 28 (sigma F) factor (fliA),
AlsR DNA-binding transcriptional repressor (rpiR),
MprA DNA-binding transcriptional repressor,
predicted DNA-binding transcriptional regulator, LYSR-type (yfeR),
LYSR-type transcriptional regulator (yeiE),
protein with similarity to transcriptional regulators (ydhB),
TdcA DNA-binding transcriptional activator,
RbsR DNA-binding transcriptional dual regulator,
PurR transcriptional repressor,
GntR DNA-binding transcriptional repressor,
Cra DNA-binding transcriptional dual regulator,
CytR,
YihL putative transcriptional regulator,
predicted DNA-binding transcriptional regulator (yegW),
YdfH DNA-binding transcriptional repressor,
LldR transcriptional dual regulator,
GlcC transcriptional dual regulator,
ExuR DNA-binding transcriptional repressor,
GlpR DNA-binding transcriptional repressor,
FucR transcriptional activator,
DeoR DNA-binding transcriptional repressor,
AgaR DNA-binding transcriptional repressor,
CRP transcriptional dual regulator,
predicted DNA-binding transcriptional regulator (ybaO),
Lrp transcriptional dual regulator,
Rob DNA-binding transcriptional dual regulator,
MelR DNA-binding transcriptional dual regulator,
MarA DNA-binding transcriptional dual regulator,
Zur,
UlaR DNA-binding transcriptional repressor,
ModE,
CueR transcriptional dual regulator,
NhaR transcriptional activator,
MetR,
GcvA DNA-binding transcriptional dual regulator,
CysB,
SoxS DNA-binding transcriptional dual regulator,
AraC,
Fur transcriptional dual regulator,
NanR DNA-binding transcriptional dual regulator,
MetJ transcriptional repressor,
TrpR,
Fis,
ArgR,
RhaR transcriptional activator,
MalT transcriptional activator,
EbgR DNA-binding transcriptional repressor,
Ada DNA-binding transcriptional dual regulator,
IlvY DNA-binding transcriptional dual regulator,
LysR DNA-binding transcriptional dual regulator,
LacI DNA-binding transcriptional repressor,
RNA polymerase, sigma 70 (sigma D) factor (rpoD),
SlyA DNA-binding transcriptional activator,
Dan-L-tartrate DNA-binding transcriptional activator,
CaiF,
TreR DNA-binding transcriptional repressor,
CdaR DNA-binding transcriptional activator,
KdgR DNA-binding transcriptional repressor,
CpxR transcriptional dual regulator,
ArcA transcriptional dual regulator,
RtcR DNA-binding transcriptional activator,
AllR DNA-binding transcriptional repressor,
HcaR transcriptional dual regulator,
FeaR DNA-binding transcriptional activator,
Nac DNA-binding transcriptional dual regulator,
AtoC transcriptional activator; Az protein inhibitor of ODC,
predicted DNA-binding transcriptional regulator, LYSR-type (abgR),
PrpR DNA-binding transcriptional dual regulator,
MurR,
DmlR DNA-binding transcriptional regulator,
McbR DNA-binding transcriptional dual regulator,
BluR DNA-binding transcriptional repressor,
NemR DNA-binding transcriptional repressor,
GadW DNA-binding transcriptional dual regulator,
Dan transcriptional activator (ttdR),
BglJ DNA-binding transcriptional regulator,
TreR transcriptional repressor,
MlrA DNA binding transcriptional activator,
AdiY DNA-binding transcriptional activator,
AscG DNA-binding transcriptional repressor,
XapR transcriptional activator,
PhnF predicted transcriptional regulator,
MngR,
RNA polymerase, sigma S (sigma 38) factor (rpoS),
FabR DNA-binding transcriptional repressor,
RutR DNA-binding transcriptional dual regulator,
EnvR DNA-binding transcriptional repressor,
AcrR DNA-binding transcriptional repressor,
ZntR transcriptional activator,
AllS transcriptional activator,
PdhR DNA-binding transcriptional dual regulator,
AsnC,
XylR transcriptional dual regulator,
MntR transcriptional dual regulator,
FNR,
FadR DNA-binding transcriptional dual regulator,
ArgP transcriptional activator,
HdfR DNA-binding transcriptional dual regulator,
RhaS,
AppY DNA-binding transcriptional activator,
GalR DNA-binding transcriptional dual regulator,
PrlF antitoxin

Unification Links: GO:0003700


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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