Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0003862 - 3-isopropylmalate dehydrogenase activity

Synonyms: (2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity, 3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity, beta-IPM dehydrogenase activity, beta-isopropylmalate dehydrogenase activity, IMDH activity, threo-Ds-3-isopropylmalate dehydrogenase activity

Definition: Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.

Parent Classes:
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Term Members:
D-malate / 3-isopropylmalate dehydrogenase (decarboxylating) (dmlA) ,

Unification Links: GO:0003862

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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