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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0004519 - endonuclease activity

Definition: Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.

Parent Classes:
GO:0004518 - nuclease activity

Child Classes:
GO:0004520 - endodeoxyribonuclease activity (25),
GO:0004521 - endoribonuclease activity (22),
GO:0016893 - endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (15),
GO:0016894 - endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters (7),
GO:0043765 - T/G mismatch-specific endonuclease activity (2)

Term Members:
Rac prophage; DNA endonuclease toxin of the RalRA toxin-antitoxin system, restriction alleviation and modification enhancement,
antitoxin of the GhoTS toxin-antitoxin system (ghoS),
flap endonuclease (ygdG),
ribosome-dependent mRNA interferase, toxin of the YafO-YafN toxin-antitoxin system,
toxin of the YafQ-DinJ toxin-antitoxin system,
multifunctional nuclease Cas1,
mRNA interferase, toxin of the MqsR-MqsA toxin-antitoxin system,
toxin of the HicA-HicB toxin-antitoxin system,
conserved protein with endonuclease activity (smrA),
endonuclease V (nfi),
YhaV toxic ribonuclease,
translation-dependent mRNA interferase, toxin of the HigB-HigA toxin-antitoxin system,
CP4-57 prophage; RNase LS, toxin of the RnlAB toxin-antitoxin system,
ChpB toxin of the ChpB-ChpS toxin-antitoxin system,
RNAse HII, degrades RNA of DNA-RNA hybrids (rnhB),
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system and cofactor to enhance the repressor activity of RelB,
endodeoxyribonuclease RUS (Holliday junction resolvase) (rusA),
MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity,
endoribonuclease involved in maturation of 16S rRNA and ribosome quality control (ybeY),
RNase P protein component; processes tRNA, 4.5S RNA (rnpA),
RNase III (rnc),
30S ribosomal subunit protein S16 (rpsP),
DNA mismatch endonuclease of the very short patch (VSP) mismatch repair pathway (vsr),
endonuclease VIII (nei),
conserved protein (yhhZ),
conserved protein (ycjD),
conserved protein (yajD),
exonuclease III (xthA),
host restriction; endonuclease R (hsdR),
crRNA endonuclease (casE),
Cas2 protein,
Cas3 nuclease/helicase,
formamidopyrimidine DNA glycosylase (mutM),
toxin of the YoeB-YefM toxin-antitoxin pair,
toxin-like protein of the SOS response (symE),
DNA-specific endonuclease I (endA),
methylated adenine and cytosine restriction protein (mrr),
restriction of DNA at 5-methylcytosine residues (mcrA),
RNase E (rne),
RNase I, cleaves phosphodiester bond between any two nucleotides,
MrcB subunit of 5-methylcytosine restriction system (mcrB),
ATP-dependent dsDNA exonuclease (sbcC),
ATP-dependent dsDNA exonuclease (sbcD),
ribonuclease G (RNAse G) monomer (rng),
RNase HI, degrades RNA of DNA-RNA hybrids, participates in DNA replication (rnhA),
endonuclease IV (nfo),

Unification Links: GO:0004519

Relationship Links: Reactome:RELATED-TO:REACT_1124, Reactome:RELATED-TO:REACT_1914, Reactome:RELATED-TO:REACT_6746, Reactome:RELATED-TO:REACT_6774, Reactome:RELATED-TO:REACT_34610, Reactome:RELATED-TO:REACT_77706, Reactome:RELATED-TO:REACT_78624, Reactome:RELATED-TO:REACT_79198, Reactome:RELATED-TO:REACT_80387, Reactome:RELATED-TO:REACT_80628, Reactome:RELATED-TO:REACT_80681, Reactome:RELATED-TO:REACT_80797, Reactome:RELATED-TO:REACT_81714, Reactome:RELATED-TO:REACT_87541, Reactome:RELATED-TO:REACT_89800, Reactome:RELATED-TO:REACT_90034, Reactome:RELATED-TO:REACT_90935, Reactome:RELATED-TO:REACT_92894, Reactome:RELATED-TO:REACT_100654, Reactome:RELATED-TO:REACT_101397, Reactome:RELATED-TO:REACT_103600, Reactome:RELATED-TO:REACT_106502, Reactome:RELATED-TO:REACT_108614, Reactome:RELATED-TO:REACT_110731, Reactome:RELATED-TO:REACT_112366, Reactome:RELATED-TO:REACT_112509, Reactome:RELATED-TO:REACT_112615, Reactome:RELATED-TO:REACT_112782, Reactome:RELATED-TO:REACT_113127, Reactome:RELATED-TO:REACT_113480, Reactome:RELATED-TO:REACT_113819, Reactome:RELATED-TO:REACT_114931, Reactome:RELATED-TO:REACT_115221, Reactome:RELATED-TO:REACT_115226, Reactome:RELATED-TO:REACT_115382, Reactome:RELATED-TO:REACT_115937, Reactome:RELATED-TO:REACT_116011

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon May 2, 2016, biocyc14.