Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0006099 - tricarboxylic acid cycle

Synonyms: citric acid cycle, Krebs cycle, TCA cycle

Definition: A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

Parent Classes:
GO:0044238 - primary metabolic process

Part Of:
GO:0009060 - aerobic respiration

Term Members:
2-methylcitrate synthase (prpC) ,
subunit of E1(0) component of 2-oxoglutarate dehydrogenase (sucA) ,
AspA ,
Ppc ,
succinate:quinone oxidoreductase ,
malate synthase G (glcB) ,
AceK ,
SucB ,
fumarate reductase iron-sulfur protein (frdB) ,
isocitrate lyase monomer (aceA) ,
malate synthase A (aceB) ,
succinyl-CoA synthetase, β subunit ,
succinyl-CoA synthetase, α subunit (sucD) ,
succinate:quinone oxidoreductase, FAD binding protein (sdhA) ,
malate dehydrogenase (mdh) ,
Icd ,
fumarase C monomer (fumC) ,
fumarase B monomer (fumB) ,
fumarase A monomer ,
malate:quinone oxidoreductase (mqo) ,
citrate synthase monomer (gltA) ,
bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase (acnB) ,
aconitate hydratase 1 (acnA) ,
succinate:quinone oxidoreductase, iron-sulfur cluster binding protein (sdhB) ,
succinate:quinone oxidoreductase, membrane protein SdhC ,
succinate:quinone oxidoreductase, membrane protein SdhC (sdhD)

Unification Links: GO:0006099


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, biocyc13.