Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0006265 - DNA topological change

Definition: The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo.

Parent Classes:
GO:0006259 - DNA metabolic process,
GO:0071103 - DNA conformation change

Term Members:
predicted DNA topoisomerase (yrdD),
DNA topoisomerase III (topB),
DNA gyrase, subunit A,
DNA topoisomerase I (topA),
topoisomerase IV subunit B (parE),
topoisomerase IV subunit A (parC),
DNA gyrase, subunit B (gyrB)

Unification Links: GO:0006265

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue Dec 1, 2015, biocyc13.