Definition: The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo.
predicted DNA topoisomerase (yrdD),
DNA topoisomerase III (topB),
DNA gyrase, subunit A,
DNA topoisomerase I (topA),
topoisomerase IV subunit B (parE),
topoisomerase IV subunit A (parC),
DNA gyrase, subunit B (gyrB)
Unification Links: GO:0006265
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