Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0006464 - cellular protein modification process

Definition: The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).

Parent Classes:
GO:0044267 - cellular protein metabolic process,
GO:0036211 - protein modification process

Child Classes:
GO:0006468 - protein phosphorylation (54),
GO:0006470 - protein dephosphorylation (16),
GO:0006486 - protein glycosylation (2),
GO:0006497 - protein lipidation (1),
GO:0006517 - protein deglycosylation (4),
GO:0008213 - protein alkylation (7),
GO:0009305 - protein biotinylation (1),
GO:0016570 - histone modification (1),
GO:0017006 - protein-tetrapyrrole linkage (8),
GO:0017013 - protein flavinylation (2),
GO:0018065 - protein-cofactor linkage (6),
GO:0018126 - protein hydroxylation (1),
GO:0018175 - protein nucleotidylation (1),
GO:0018193 - peptidyl-amino acid modification (72),
GO:0018215 - protein phosphopantetheinylation (2),
GO:0018249 - protein dehydration (1),
GO:0018282 - metal incorporation into metallo-sulfur cluster (1),
GO:0018298 - protein-chromophore linkage (2),
GO:0018307 - enzyme active site formation (1),
GO:0019988 - charged-tRNA amino acid modification (1),
GO:0031162 - sulfur incorporation into metallo-sulfur cluster (2),
GO:0031365 - N-terminal protein amino acid modification (17),
GO:0035601 - protein deacylation (4),
GO:0042040 - metal incorporation into metallo-molybdopterin complex (2),
GO:0043543 - protein acylation (20),
GO:0043686 - co-translational protein modification (1),
GO:0043687 - post-translational protein modification (7),
GO:0046944 - protein carbamoylation (1),
GO:0070084 - protein initiator methionine removal (1),
GO:0070647 - protein modification by small protein conjugation or removal (1),
GO:0070930 - trans-translation-dependent protein tagging (2)

Term Members:
molybdopterin-synthase adenylyltransferase (moeB),
L-isoaspartate protein carboxylmethyltransferase type II (pcm),
ThiS adenylyltransferase (thiF),
predicted maturation peptidase for hydrogenase 2 (hybD),
protein involved in processing of HyaA and HyaB proteins (hyaD),
lipoate-protein ligase A (lplA),
ribosomal-protein-L12-serine acetyltransferase (rimL),
ribosomal protein S6 modification protein (rimK),
ribosomal-protein-S5-alanine N-acetyltransferase (rimJ),
ribosomal-protein-S18-alanine N-acetyltransferase (rimI),
methionine sulfoxide reductase A (msrA),
hydrogenase 3 maturation protease (hycI),
protein involved with the maturation of hydrogenases 1 and 2 (hybF),
accessory protein for nickel incorporation into hydrogenase 3 (hypA),
bifunctional biotin-[acetyl-CoA-carboxylase] ligase and transcriptional repressor (birA),
flavodoxin involved in dimanganese-tyrosyl radical cofactor maintenance for ribonucleotide reductase (nrdI),
lipoyl(octanoyl) transferase (lipB),
citrate lyase synthetase (citC),
PII uridylyltransferase / uridylyl removing enzyme (glnD),
phosphohistidine phosphatase (sixA),
HypD, scaffold protein for assembly of the Fe-(CN)2CO cofactor

Unification Links: GO:0006464

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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