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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0006950 - response to stress

Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Summary:
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.

Parent Classes:
GO:0050896 - response to stimulus

Child Classes:
GO:0001666 - response to hypoxia (1) ,
GO:0006952 - defense response (25) ,
GO:0006970 - response to osmotic stress (34) ,
GO:0006979 - response to oxidative stress (86) ,
GO:0009271 - phage shock (4) ,
GO:0009408 - response to heat (57) ,
GO:0009409 - response to cold (16) ,
GO:0033554 - cellular response to stress (338) ,
GO:0034059 - response to anoxia (2) ,
GO:0035966 - response to topologically incorrect protein (3) ,
GO:0042594 - response to starvation (33) ,
GO:0051409 - response to nitrosative stress (3) ,
GO:0051599 - response to hydrostatic pressure (1) ,
GO:0097501 - stress response to metal ion (6) ,
GO:0097532 - stress response to acid chemical (3)

Term Members:
RclR DNA-binding transcriptional activator ,
predicted oxidoreductase with FAD/NAD(P)-binding domain and dimerization domain; hypochlorite stress response (rclA) ,
predicted protein, hypochlorite stress response (rclB) ,
conserved inner membrane protein, hypochlorite stress response (rclC) ,
small predicted membrane protein (yniD) ,
small protein involved in the acid stress response (yqgB) ,
small protein involved in stress responses (yobF) ,
cytochrome bd-I terminal oxidase - CydX subunit ,
small outer membrane protein (appX) ,
small membrane protein that interacts with the AcrAB-TolC multidrug efflux pump (acrZ) ,
small protein (ilvX) ,
small protein (yqeL) ,
small membrane protein (ypdK) ,
small membrane protein (yohP) ,
small protein (yoeI) ,
small membrane protein (azuC) ,
small protein (yobI) ,
small membrane protein (yoaJ) ,
small membrane protein (yoaK) ,
small membrane protein (ykgR) ,
small predicted membrane protein (ythA) ,
small protein (ypfM) ,
small stress response membrane protein (ynhF) ,
small membrane protein (yneM) ,
small membrane protein (yncL) ,
chaperone, protecting proteins in response to oxidative stress (yajL) ,
inhibitor of σS proteolysis (iraM) ,
ClpB chaperone ,
iron-sulfur cluster scaffold protein (nfuA) ,
β-lactam resistance protein (blr) ,
heat shock protein HslJ ,
D-lactate dehydrogenase - fermentative (ldhA) ,
inhibitor of σS proteolysis (iraD) ,
conserved protein (bsmA) ,
nucleotide binding filament protein (uspF) ,
AidB ,
phage shock protein G (pspG) ,
KdpD ,
BetB ,
choline dehydrogenase (betA) ,
peptide transporter induced by carbon starvation (cstA) ,
DegP ,
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system and cofactor to enhance the repressor activity of RelB ,
small heat shock protein IbpB ,
small heat shock protein IbpA ,
RNA polymerase, sigma 24 (sigma E) factor (rpoE) ,
ribosome modulation factor (rmf) ,
regulatory protein for the phage shock protein operon (pspA) ,
stationary phase translation inhibitor and ribosome stability factor (raiA) ,
heat shock protein Hsp15 involved in ribosome recycling (hslR) ,
stationary phase nucleoid protein that sequesters iron and protects DNA from damage (dps) ,
anti-adaptor protein for σS stabilization (iraP) ,
CspA DNA-binding transcriptional activator ,
DeaD, DEAD-box RNA helicase ,
DNA replication inhibitor (cspD) ,
protein that protects iron-sulfur proteins against oxidative damage (yggX) ,
DNA strand exchange and recombination protein with protease and nuclease activity (recA) ,
peptidase component of the HslVU protease ,
HtpG monomer ,
chaperone for [Fe-S] cluster biosynthesis (hscA) ,
chaperone protein DnaK ,
molecular chaperone Hsp33 (hslO) ,
ATPase component of the HslVU protease (hslU) ,
ClpP ,
nucleotide exchange factor GrpE ,
chaperone protein DnaJ ,
outer membrane metallopeptidase (loiP) ,
regulator of RpoS (rssB) ,
phosphosugar phosphatase (yigL) ,
50S ribosomal subunit-binding toxin of a predicted toxin-antitoxin pair (ratA) ,
predicted universal stress (ethanol tolerance) protein B (uspB) ,
predicted chaperone (ygeG) ,
universal stress protein (uspC) ,
universal stress global stress response regulator (uspA) ,
thiosulfate sulfurtransferase (pspE) ,
regulator of the Cpx response and possible chaperone involved in resistance to extracytoplasmic stress (cpxP) ,
RNA polymerase, sigma S (sigma 38) factor (rpoS) ,
paraquat-inducible protein A (pqiA) ,
serine endoprotease, periplasmic (degQ) ,
ribosome-dependent mRNA interferase, toxin of the YafO-YafN toxin-antitoxin system ,
toxin of the HicA-HicB toxin-antitoxin system ,
translation-dependent mRNA interferase, toxin of the HigB-HigA toxin-antitoxin system ,
DNA gyrase inhibitor (sbmC) ,
RNase R (rnr) ,
MazF toxin of the MazF-MazE toxin-antitoxin system that exhibits ribonuclease activity ,
O-acetyl-ADP-ribose deacetylase, regulator of RNase III activity (ymdB) ,
RseP zinc protease, signal peptide peptidase ,
anti-sigma factor (rseA) ,
MicA small regulatory RNA ,
trehalose-6-phosphate synthase (otsA) ,
conserved protein (ves) ,
two-component system connector protein (safA) ,
RNA-binding protein that affects many cellular processes; homolog of mammalian Sm/Sm-like proteins (hfq) ,
heat shock protein, hemimethylated DNA-binding protein (hspQ) ,
SgrS small regulatory RNA ,
Hsc62, Hsp70 family chaperone, binds to RpoD and inhibits transcription (hscC) ,
D-cysteine desulfhydrase (dcyD) ,
aldehyde dehydrogenase (astD) ,
AstB ,
succinylglutamate desuccinylase (astE) ,
stress-induced alternate pyruvate formate-lyase subunit (grcA) ,
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD) ,
ClcA ,
Qin prophage; cold shock protein; predicted DNA-binding transcriptional regulator (cspB) ,
putative outer membrane usher protein (htrE) ,
probable pilin chaperone similar to PapD (yadV) ,
glyoxalase III, Hsp31 molecular chaperone (hchA) ,
conserved protein (yjaZ) ,
heat shock protein, integral membrane protein (htpX) ,
23S rRNA 2'-O-ribose U2552 methyltransferase (rlmE) ,
RelB Qin prophage; antitoxin of the RelE-RelB toxin-antitoxin system and DNA binding transcriptional repressor ,
IscR DNA-binding transcriptional dual regulator ,
RNA polymerase, sigma 32 (sigma H) factor (rpoH) ,
phosphate ABC transporter - periplasmic binding protein (pstS) ,
SspB ,
peripheral inner membrane phage-shock protein (pspD) ,
PspC transcriptional regulator; toxin of a PspC-PspB toxin-antitoxin pair ,
stimulates PspC-mediated transcriptional activation of the psp operon; antitoxin of a PspC-PspB toxin-antitoxin pair ,
transcription termination/antitermination L factor (nusA) ,
arginine succinyltransferase (astA) ,
periplasmic folding chaperone (ppiD) ,
lauroyl acyltransferase (lpxL) ,
stringent starvation protein A (sspA) ,
choline:H+ symporter (betT) ,
Lon ,
ATP-binding protein (phoH) ,
cold shock protein CspG ,
3,4-dihydroxy-2-butanone 4-phosphate synthase (ribB) ,
ClpX ,
polynucleotide phosphorylase monomer (pnp) ,
PhoE ,
RybB small regulatory RNA ,
outer membrane protein involved in copper permeability, stress resistance and biofilm formation (bhsA) ,
antitoxin of the HicA-HicB toxin-antitoxin system ,
protein involved in repair of stress-damaged iron-sulfur clusters (ytfE) ,
diguanylate cyclase (dosC) ,
universal stress protein UP12 (uspG) ,
stress protein involved in resistance to UV irradiation (uspD) ,
universal stress protein with a role cellular motility (uspE) ,
conserved DNA-binding protein (ybaB)

Unification Links: GO:0006950


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Dec 18, 2014, biocyc13.