Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0007165 - signal transduction

Synonyms: GO:0023033

Definition: The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.

Parent Classes:
GO:0050794 - regulation of cellular process

Part Of:
GO:0044700 - single organism signaling

Child Classes:
GO:0007231 - osmosensory signaling pathway (1),
GO:0023014 - signal transduction by protein phosphorylation (34),
GO:0030522 - intracellular receptor signaling pathway (1),
GO:0035556 - intracellular signal transduction (97)

Term Members:
inositol monophosphatase (suhB),
RcsF outer membrane lipoprotein - activates the Rcs pathway during envelope stress,
positive DNA-binding transcriptional regulator of capsular polysaccharide synthesis, activates its own expression (rcsA),
RcsC sensory histidine kinase,
blue light-responsive regulator of BluR (bluF),
AtoS monomer,
DpiB sensory histidine kinase,
CusS sensory histidine kinase,
GlrK sensory histidine kinase,
TorS monomer,
BaeS sensory histidine kinase,
BasS sensory histidine kinase,
PhoQ monomer,
RstB sensory histidine kinase,
DcuS sensory histidine kinase,
BarA sensory histidine kinase,
ArcB sensory histidine kinase,
CpxA sensory histidine kinase,
predicted sensory kinase in two-component regulatory system with YedW (yedV),
predicted diguanylate cyclase (dgcN),
predicted c-di-GMP phosphodiesterase (pdeK),
aerotaxis sensor receptor, flavoprotein,

Unification Links: GO:0007165

Relationship Links: Reactome:RELATED-TO:REACT_12478, Reactome:RELATED-TO:REACT_31232, Reactome:RELATED-TO:REACT_78535, Reactome:RELATED-TO:REACT_89740, Reactome:RELATED-TO:REACT_93680, Reactome:RELATED-TO:REACT_98872, Reactome:RELATED-TO:REACT_100624, Reactome:RELATED-TO:REACT_102354, Reactome:RELATED-TO:REACT_112130, Reactome:RELATED-TO:REACT_112549, Reactome:RELATED-TO:REACT_113151, Reactome:RELATED-TO:REACT_113601, Reactome:RELATED-TO:REACT_113964, Reactome:RELATED-TO:REACT_114657, Reactome:RELATED-TO:REACT_114690, Reactome:RELATED-TO:REACT_114820, Reactome:RELATED-TO:REACT_114910, Reactome:RELATED-TO:REACT_115037, Reactome:RELATED-TO:REACT_115147, Wikipedia:RELATED-TO:Signal_transduction

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Thu May 5, 2016, biocyc14.