Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0008233 - peptidase activity

Synonyms: hydrolase, acting on peptide bonds, peptide hydrolase activity, protease activity, proteinase activity

Definition: Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

Parent Classes:
GO:0016787 - hydrolase activity

Child Classes:
GO:0070011 - peptidase activity, acting on L-amino acid peptides (92)

Term Members:
chaperone/protease involved in the maintenance of OM integrity (bepA),
protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD (tldD),
protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD (pmbA),
predicted protein (yedK),
γ-glutamyltranspeptidase (ggt),
D-Ala-D-Ala dipeptidase (ddpX),
broad-specificity exoaminopeptidase (ypdE),
aminopeptidase (ypdF),
L,D-carboxypeptidase A (ldcA),
aminopeptidase A/I (pepA),
DD-carboxypeptidase, penicillin-binding protein 6b (dacD),
peptidase T,
outer membrane metallopeptidase (loiP),
dipeptidyl carboxypeptidase II (dcp),
heat shock protein, integral membrane protein (htpX),
tail-specific protease (prc),
RseP zinc protease, signal peptide peptidase,
D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 (dacA),
methionine aminopeptidase (map),
DD-endopeptidase / DD-carboxypeptidase (ampH),
intramembrane serine protease GlpG,
outer membrane protease VII (outer membrane protein 3b) (ompT),
penicillin-binding protein 6 (dacC),
protease IV (sppA),
protease III (ptrA),
aminopeptidase N (pepN),
predicted protease (yhbV),
oligopeptidase B (ptrB),
Deg S monomer (degS),
predicted lipoprotein and C40 family peptidase (yafL),
murein DD-endopeptidase MepH,
predicted lipoprotein (yaeF),
NlpC-putative lipoprotein hydrolase,
murein DD-endopeptidase / murein LD-carboxypeptidase (mepS),
KpLE2 phage-like element; predicted endoglucanase with Zn-dependent exopeptidase domain (sgcX),
frv operon protein (frvX),
deubiquitinase (elaD),
Rac prophage; predicted defective peptidase (rzpR),
predicted peptidase (yegQ),
predicted peptidase (ydgD),
predicted peptidase (ydcP),
putative ATP-dependent protease (ycbZ),
DLP12 prophage; predicted murein endopeptidase (rzpD),
predicted peptidase (ygeY),
predicted peptidase (collagenase-like) (yhbU),
predicted peptidase with chaperone function (ycaL),
serine endoprotease, periplasmic monomer (degQ),
predicted zinc-dependent peptidase (yhjJ),
predicted maturation peptidase for hydrogenase 2 (hybD),
aminopeptidase B (pepB),
putative zinc peptidase (pqqL),
oligopeptidase A (prlC),
leader peptidase, integral membrane protein (gspO),
Xaa-Pro dipeptidase (pepQ),
protein involved in processing of HyaA and HyaB proteins (hyaD),
peptidase D (pepD),
alkaline phosphatase isozyme conversion protein (iap),
predicted inner membrane peptidase (sohB),
SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC,
murein DD-endopeptidase MepM,
hydrogenase 3 maturation protease (hycI),
ATP-dependent zinc metalloprotease FtsH,
peptidase E, a dipeptidase where amino-terminal residue is aspartate (pepE),
prolipoprotein signal peptidase II (lspA),
leader peptidase (signal peptidase I) (lepB),
peptidase component of the HslVU protease,
Lit, cell death peptidase; phage exclusion; e14 prophage

Unification Links: GO:0008233

Relationship Links: ENZYME:RELATED-TO:3.4, Reactome:RELATED-TO:REACT_13710, Reactome:RELATED-TO:REACT_19284, Reactome:RELATED-TO:REACT_93020, Reactome:RELATED-TO:REACT_99630, Reactome:RELATED-TO:REACT_106748, Reactome:RELATED-TO:REACT_110349

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.5 on Wed Nov 25, 2015, BIOCYC11A.