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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0008237 - metallopeptidase activity

Synonyms: metalloprotease activity, metalloproteinase activity

Definition: Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Parent Classes:
GO:0070011 - peptidase activity, acting on L-amino acid peptides

Child Classes:
GO:0004222 - metalloendopeptidase activity (14),
GO:0008235 - metalloexopeptidase activity (8)

Term Members:
protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD (tldD),
protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD (pmbA),
chaperone/protease involved in the maintenance of OM integrity (bepA),
D-Ala-D-Ala dipeptidase (ddpX),
heat shock protein, integral membrane protein (htpX),
RseP zinc protease, signal peptide peptidase,
Mlc titration factor (mtfA),
ArgE,
N-succinyl-L-diaminopimelate desuccinylase subunit (dapE),
KpLE2 phage-like element; predicted endoglucanase with Zn-dependent exopeptidase domain (sgcX),
frv operon protein (frvX),
N6-L-threonylcarbamoyladenine synthase, TsaB subunit,
broad-specificity exoaminopeptidase (ypdE),
predicted peptidase (ygeY),
predicted peptidase with chaperone function (ycaL),
IadA,
predicted zinc-dependent peptidase (yhjJ),
putative zinc peptidase (pqqL),
peptidase T,
oligopeptidase A (prlC),
outer membrane metallopeptidase (loiP),
dipeptidyl carboxypeptidase II (dcp),
Xaa-Pro dipeptidase (pepQ),
peptidase D (pepD),
PepP,
MepA,
murein DD-endopeptidase MepM,
ATP-dependent zinc metalloprotease FtsH,
protease III (ptrA),
aminopeptidase N (pepN)

Unification Links: GO:0008237

Relationship Links: Reactome:RELATED-TO:REACT_267, Reactome:RELATED-TO:REACT_410, Reactome:RELATED-TO:REACT_1011, Reactome:RELATED-TO:REACT_1552, Reactome:RELATED-TO:REACT_13658, Reactome:RELATED-TO:REACT_18387, Reactome:RELATED-TO:REACT_28662, Reactome:RELATED-TO:REACT_29018, Reactome:RELATED-TO:REACT_30292, Reactome:RELATED-TO:REACT_30924, Reactome:RELATED-TO:REACT_33366, Reactome:RELATED-TO:REACT_33539, Reactome:RELATED-TO:REACT_33732, Reactome:RELATED-TO:REACT_33852, Reactome:RELATED-TO:REACT_33929, Reactome:RELATED-TO:REACT_77236, Reactome:RELATED-TO:REACT_78816, Reactome:RELATED-TO:REACT_79691, Reactome:RELATED-TO:REACT_79817, Reactome:RELATED-TO:REACT_81981, Reactome:RELATED-TO:REACT_83198, Reactome:RELATED-TO:REACT_83310, Reactome:RELATED-TO:REACT_83988, Reactome:RELATED-TO:REACT_89528, Reactome:RELATED-TO:REACT_89928, Reactome:RELATED-TO:REACT_91564, Reactome:RELATED-TO:REACT_92210, Reactome:RELATED-TO:REACT_92309, Reactome:RELATED-TO:REACT_92841, Reactome:RELATED-TO:REACT_93042, Reactome:RELATED-TO:REACT_94705, Reactome:RELATED-TO:REACT_95173, Reactome:RELATED-TO:REACT_95565, Reactome:RELATED-TO:REACT_96136, Reactome:RELATED-TO:REACT_96651, Reactome:RELATED-TO:REACT_96860, Reactome:RELATED-TO:REACT_96983, Reactome:RELATED-TO:REACT_97764, Reactome:RELATED-TO:REACT_98127, Reactome:RELATED-TO:REACT_98562, Reactome:RELATED-TO:REACT_99318, Reactome:RELATED-TO:REACT_100129, Reactome:RELATED-TO:REACT_100372, Reactome:RELATED-TO:REACT_100593, Reactome:RELATED-TO:REACT_100677, Reactome:RELATED-TO:REACT_100694, Reactome:RELATED-TO:REACT_101972, Reactome:RELATED-TO:REACT_102999, Reactome:RELATED-TO:REACT_103085, Reactome:RELATED-TO:REACT_104327, Reactome:RELATED-TO:REACT_104368, Reactome:RELATED-TO:REACT_107504, Reactome:RELATED-TO:REACT_109423, Reactome:RELATED-TO:REACT_109532, Reactome:RELATED-TO:REACT_114094, Reactome:RELATED-TO:REACT_115138


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sat Feb 13, 2016, biocyc14.