Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0008657 - DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

Synonyms: DNA gyrase inhibitor activity

Definition: Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.

Parent Classes:
GO:0072586 - DNA topoisomerase (ATP-hydrolyzing) regulator activity ,
GO:0042030 - ATPase inhibitor activity

Term Members:
DNA gyrase inhibitor (sbmC) ,
DNA gyrase inhibitor YacG

Unification Links: GO:0008657


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Mon Nov 24, 2014, BIOCYC13B.