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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0009103 - lipopolysaccharide biosynthetic process

Synonyms: lipopolysaccharide anabolism, lipopolysaccharide biosynthesis, lipopolysaccharide formation, lipopolysaccharide synthesis, LPS biosynthetic process

Definition: The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.

Parent Classes:
GO:0008653 - lipopolysaccharide metabolic process,
GO:1901137 - carbohydrate derivative biosynthetic process,
GO:0033692 - cellular polysaccharide biosynthetic process,
GO:0008610 - lipid biosynthetic process

GO:0019294 - keto-3-deoxy-D-manno-octulosonic acid biosynthetic process (4),
GO:0009245 - lipid A biosynthetic process (22),
GO:0009244 - lipopolysaccharide core region biosynthetic process (21),
GO:0009243 - O antigen biosynthetic process (9)

Term Members:
Kdo2-lipid A phosphotransferase (lpxT),
palmitoleoyl acyltransferase (lpxP),
fused UDP-L-Ara4N formyltransferase and UDP-GlcA C-4''-decarboxylase (arnA),
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD),
D,D-heptose 1,7-bisphosphate phosphatase (gmhB),
D-sedoheptulose 7-phosphate isomerase (lpcA),
D-arabinose 5-phosphate isomerase (kdsD),
ADP-heptose:LPS heptosyltransferase II (waaF),
Kdo2-lipid A phosphoethanolamine 7''-transferase (eptB),
O-antigen ligase (waaL),
protein involved in KdoIII attachment during lipopolysaccharide core biosynthesis (waaZ),
lipopolysaccharide core biosynthesis protein (waaS),
lipopolysaccharide core heptosyltransferase III (waaQ),
lipopolysaccharide core heptose (I) kinase (waaP),
lipopolysaccharide glucosyltransferase I (waaG),
ADP-heptose:LPS heptosyltransferase I (waaC),
D-arabinose 5-phosphate isomerase (gutQ),
lauroyl acyltransferase (lpxL),
KDO transferase (waaA),
3-deoxy-D-manno-octulosonate 8-phosphate synthase (kdsA),
3-deoxy-D-manno-octulosonate cytidylyltransferase (kdsB),
protein-tyrosine kinase (wzc),
autophosphorylating protein tyrosine kinase (etk),
ferric enterobactin (enterochelin) transport (fepE),
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase monomer (kdsC),
UTP--glucose-1-phosphate uridylyltransferase (galU),
phosphoethanolamine transferase EptC,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnE subunit,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnF subunit,
conserved protein (arnD),
phosphoethanolamine transferase EptA,
UDP-L-Ara4O C-4" transaminase (arnB),
predicted colanic acid biosynthesis glycosyl transferase (wcaA),
fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (rfaE),
4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase (arnT),
regulator of length of O-antigen component of lipopolysaccharide chains (wzzB),
predicted colanic acid biosynthesis protein (wcaM),
predicted colanic biosynthesis glycosyl transferase (wcaL),
predicted colanic acid biosynthesis pyruvyl transferase (wcaK),
undecaprenyl-phosphate glucose phosphotransferase (wcaJ),
predicted colanic acid biosynthesis glycosyl transferase (wcaE),
predicted colanic acid polymerase (wcaD),
predicted colanic acid biosynthesis glycosyl transferase (wcaC),
dTDP-4-dehydrorhamnose reductase (rfbD),
dTDP-glucose 4,6-dehydratase (rfbB),
predicted lipopolysaccharide biosynthesis protein (wbbK),
β-1,6-galactofuranosyltransferase (wbbI),
predicted O-antigen polymerase (wbbH),
UDP-galactopyranose mutase (glf),
O-antigen flippase (rfbX),
dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC),
lipopolysaccharide biosynthesis protein, N-ter fragment (wbbL_1),
predicted colanic biosynthesis glycosyl transferase (wcaI),
dTDP-glucose 4,6-dehydratase 2 (rffG),
lipopolysaccharide core biosynthesis; heptosyl transferase IV; probably hexose transferase (waaU),
lipopolysaccharide core heptose (II) kinase (waaY),
UDP-glucose:(glucosyl)LPS α-1,2-glucosyltransferase (waaJ),
UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase (waaB),
myristoyl-acyl carrier protein (ACP)-dependent acyltransferase (lpxM),
phosphomannomutase (cpsG),
mannose-1-phosphate guanylyltransferase (cpsB),
Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein (wzzE),
predicted acyl transferase (wcaF),
predicted colanic acid biosynthesis acyl transferase (wcaB),
predicted uridylyltransferase subunit with GalU (galF),
undecaprenyl phosphate-L-Ara4FN transferase (arnC),
predicted acyl transferase (wbbJ),
UDP-D-glucose:(glucosyl)LPS α-1,3-glucosyltransferase (waaO),
involved in lipopolysaccharide biosynthesis (htrL)

Unification Links: GO:0009103

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue May 3, 2016, biocyc13.