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discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
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discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0009103 - lipopolysaccharide biosynthetic process

Synonyms: lipopolysaccharide anabolism, lipopolysaccharide biosynthesis, lipopolysaccharide formation, lipopolysaccharide synthesis, LPS biosynthetic process

Definition: The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.

Parent Classes:
GO:0033692 - cellular polysaccharide biosynthetic process ,
GO:0008653 - lipopolysaccharide metabolic process ,
GO:1901137 - carbohydrate derivative biosynthetic process ,
GO:0008610 - lipid biosynthetic process

Parts:
GO:0019294 - keto-3-deoxy-D-manno-octulosonic acid biosynthetic process (4) ,
GO:0009245 - lipid A biosynthetic process (21) ,
GO:0009244 - lipopolysaccharide core region biosynthetic process (25) ,
GO:0009243 - O antigen biosynthetic process (12)

Term Members:
fused UDP-L-Ara4N formyltransferase and UDP-GlcA C-4''-decarboxylase (arnA) ,
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD) ,
D,D-heptose 1,7-bisphosphate phosphatase (gmhB) ,
D-sedoheptulose 7-phosphate isomerase (lpcA) ,
D-arabinose 5-phosphate isomerase (kdsD) ,
ADP-heptose:LPS heptosyltransferase II (waaF) ,
phosphoethanolamine transferase EptB ,
O-antigen ligase (waaL) ,
protein involved in KdoIII attachment during lipopolysaccharide core biosynthesis (waaZ) ,
lipopolysaccharide core biosynthesis protein (waaS) ,
lipopolysaccharide core heptosyl transferase III (waaQ) ,
lipopolysaccharide core heptose (I) kinase (waaP) ,
lipopolysaccharide glucosyltransferase I (waaG) ,
ADP-heptose:LPS heptosyltransferase I (waaC) ,
D-arabinose 5-phosphate isomerase (gutQ) ,
lauroyl acyltransferase (lpxL) ,
KDO transferase (waaA) ,
3-deoxy-D-manno-octulosonate 8-phosphate synthase (kdsA) ,
3-deoxy-D-manno-octulosonate cytidylyltransferase (kdsB) ,
protein-tyrosine kinase (wzc) ,
autophosphorylating protein tyrosine kinase (etk) ,
pH-inducible protein involved in stress response (inaA) ,
ferric enterobactin (enterochelin) transport (fepE) ,
GlmU ,
Ugd ,
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase monomer (kdsC) ,
UTP--glucose-1-phosphate uridylyltransferase (galU) ,
phosphoethanolamine transferase EptC ,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnE subunit ,
undecaprenyl-phosphate-α-L-Ara4N flippase - ArnF subunit ,
conserved protein (arnD) ,
phosphoethanolamine transferase EptA ,
UDP-L-Ara4O C-4" transaminase (arnB) ,
predicted colanic acid biosynthesis glycosyl transferase (wcaA) ,
WzxC ,
fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (rfaE) ,
4-amino-4-deoxy-L-arabinose (L-Ara4N) transferase (arnT) ,
regulator of length of O-antigen component of lipopolysaccharide chains (wzzB) ,
predicted colanic acid biosynthesis protein (wcaM) ,
predicted colanic biosynthesis glycosyl transferase (wcaL) ,
predicted colanic acid biosynthesis pyruvyl transferase (wcaK) ,
predicted colanic acid biosynthsis UDP-glucose lipid carrier transferase (wcaJ) ,
predicted colanic acid biosynthesis glycosyl transferase (wcaE) ,
predicted colanic acid polymerase (wcaD) ,
predicted colanic acid biosynthesis glycosyl transferase (wcaC) ,
dTDP-4-dehydrorhamnose reductase (rfbD) ,
dTDP-glucose 4,6-dehydratase (rfbB) ,
predicted lipopolysaccharide biosynthesis protein (wbbK) ,
β-1,6-galactofuranosyltransferase (wbbI) ,
predicted O-antigen polymerase (wbbH) ,
UDP-galactopyranose mutase (glf) ,
O-antigen flippase (rfbX) ,
dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) ,
RfbA ,
lipopolysaccharide biosynthesis protein, N-ter fragment (wbbL_1) ,
predicted colanic biosynthesis glycosyl transferase (wcaI) ,
Gmm ,
dTDP-4-dehydro-6-deoxy-D-glucose transaminase (rffA) ,
dTDP-fucosamine acetyltransferase (rffC) ,
dTDP-glucose 4,6-dehydratase 2 (rffG) ,
lipopolysaccharide core biosynthesis; heptosyl transferase IV; probably hexose transferase (waaU) ,
lipopolysaccharide core heptose (II) kinase (waaY) ,
UDP-glucose:(glucosyl)LPS α-1,2-glucosyltransferase (waaJ) ,
UDP-D-galactose:(glucosyl)lipopolysaccharide-1,6-D-galactosyltransferase (waaB) ,
myristoyl-acyl carrier protein (ACP)-dependent acyltransferase (lpxM) ,
phosphomannomutase (cpsG) ,
mannose-1-phosphate guanylyltransferase (cpsB) ,
Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein (wzzE) ,
predicted acyl transferase (wcaF) ,
predicted colanic acid biosynthesis acyl transferase (wcaB) ,
Rfe ,
predicted uridylyltransferase subunit with GalU (galF) ,
undecaprenyl phosphate-L-Ara4FN transferase (arnC) ,
predicted acyl transferase (wbbJ) ,
UDP-D-glucose:(glucosyl)LPS α-1,3-glucosyltransferase (waaO) ,
involved in lipopolysaccharide biosynthesis (htrL)

Unification Links: GO:0009103


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, biocyc12.