Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0009307 - DNA restriction-modification system

Definition: A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

Parent Classes:
GO:0006304 - DNA modification ,
GO:0044355 - clearance of foreign intracellular DNA

Term Members:
DNA-cytosine methyltransferase (dcm) ,
Rac prophage; DNA endonuclease toxin of the RalRA toxin-antitoxin system, restriction alleviation and modification enhancement ,
restriction of DNA at 5-methylcytosine residues (mcrA) ,
methylated adenine and cytosine restriction protein (mrr) ,
MrcC subunit of 5-methylcytosine restriction system (mcrC) ,
MrcB subunit of 5-methylcytosine restriction system (mcrB) ,
specificity determinant for hsdM and hsdR (hsdS) ,
host restriction; endonuclease R (hsdR) ,
host modification; DNA methylase M (hsdM)

Unification Links: GO:0009307

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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