Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0016790 - thiolester hydrolase activity

Synonyms: thiolesterase activity

Definition: Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.

Parent Classes:
GO:0016788 - hydrolase activity, acting on ester bonds

Child Classes:
GO:0004416 - hydroxyacylglutathione hydrolase activity (3),
GO:0008474 - palmitoyl-(protein) hydrolase activity (1),
GO:0016289 - CoA hydrolase activity (8),
GO:0018738 - S-formylglutathione hydrolase activity (2)

Term Members:
1,4-dihydroxy-2-naphthoyl-CoA thioesterase (menI),
phenylacetyl-CoA thioesterase (paaI),
esterase/thioesterase (ybgC),
proofreading thioesterase in enterobactin biosynthesis (entH),
esterase (ybfF)

Unification Links: GO:0016790

Relationship Links: ENZYME:RELATED-TO:3.1.2

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon Nov 30, 2015, biocyc11.