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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0016853 - isomerase activity

Definition: Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.

Note that enzymes of class EC:5.99.-.- should also be annotated to this term.

Parent Classes:
GO:0003824 - catalytic activity

Child Classes:
GO:0003916 - DNA topoisomerase activity (7),
GO:0008719 - dihydroneopterin triphosphate 2'-epimerase activity (1),
GO:0016854 - racemase and epimerase activity (29),
GO:0016859 - cis-trans isomerase activity (10),
GO:0016860 - intramolecular oxidoreductase activity (33),
GO:0016866 - intramolecular transferase activity (38),
GO:0016872 - intramolecular lyase activity (1),
GO:0051075 - S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (1),
GO:0061593 - sulfoquinovose isomerase activity (1)

Term Members:
dihydroneopterin aldolase (folB),
fumarase A monomer,
phospho-AI-2 isomerase (lsrG),
isopentenyl diphosphate isomerase (idi),
β-phosphoglucomutase (ycjU),
23S rRNA pseudouridine 2457 synthase (rluE),
ADP-L-glycero-D-mannoheptose-6-epimerase (rfaD),
D-sedoheptulose 7-phosphate isomerase (lpcA),
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase monomer (gpmA),
tRNA pseudouridine 55 synthase (truB),
L-Ala-D/L-Glu epimerase (ycjG),
D-arabinose 5-phosphate isomerase (kdsD),
N-acetylneuraminate mutarotase (nanM),
L-ribulose 5-phosphate 4-epimerase (ulaF),
L-xylulose 5-phosphate 3-epimerase (ulaE),
lysine 2,3-aminomutase (epmB),
23S rRNA pseudouridine 2605 synthase (rluB),
UDP-galactopyranose mutase (glf),
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmM),
L-ribulose-5-phosphate 4-epimerase (sgbE),
allose-6-phosphate isomerase / ribose-5-phosphate isomerase B monomer (rpiB),
phosphoglucomutase (pgm),
23S rRNA pseudouridine synthase (rluD),
allulose-6-phosphate 3-epimerase (alsE),
23S rRNA pseudouridine 2604 synthase (rluF),
L-rhamnose isomerase (rhaA),
L-rhamnose mutarotase,
sulfoquinovose isomerase (yihS),
NAD(P)HX epimerase / NAD(P)HX dehydratase (yjeF),
phosphoglucosamine mutase (glmM),
peptidyl-prolyl cis-trans isomerase B (rotamase B) (ppiB),
D-arabinose 5-phosphate isomerase (gutQ),
DNA topoisomerase III (topB),
N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'-phosphoribosyl)-4-imidazolecarboxamide isomerase (hisA),
ribulose-5-phosphate 3-epimerase (rpe),
peptidyl-prolyl cis-trans isomerase A (rotamase A) (ppiA),
DNA gyrase, subunit B (gyrB),
DNA gyrase, subunit A,
L-fucose mutarotase (fucU),
peptidyl-prolyl cis-trans isomerase (fkpB),
isochorismate synthase 1 (entC),
dihydroneopterin triphosphate 2'-epimerase monomer (folX),
peptidyl-prolyl cis-trans isomerase (PPIase) (surA),
16S rRNA pseudouridine 516 synthase (rsuA),
tRNA pseudouridine 65 synthase (truC),
23S rRNA pseudouridine synthase (rluC),
23S rRNA and tRNA pseudouridine synthase (rluA),
peptidyl-prolyl cis-trans isomerase C (rotamase C) (ppiC),
FKBP-type peptidyl prolyl cis-trans isomerase (slyD),
galactose-1-epimerase (galM),
D-glucuronate isomerase / D-galacturonate isomerase (uxaC),
triosephosphate isomerase monomer (tpiA),
chaperone protein Tig; trigger factor,
ribose-5-phosphate isomerase A (rpiA),
S-adenosylmethionine:tRNA ribosyltransferase-isomerase (queA),
alanine racemase 1, PLP-binding, biosynthetic subunit (alr),
UDP-glucose 4-epimerase monomer (galE),
L-ribulose 5-phosphate 4-epimerase monomer (araD),
L-arabinose isomerase monomer (araA),
tRNA pseudouridine synthase I (truA),
DNA topoisomerase I (topA),
ribose pyranase (rbsD),
mannose-6-phosphate isomerase (manA),
indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC),
conserved protein (ygbM),
conserved protein (yphB),
predicted aldose-1-epimerase (yihR),
predicted ring 1,2-epoxyphenylacetyl-CoA isomerase (oxepin-CoA forming) (paaG),
conserved protein (ybhH),
tRNA pseudouridine 13 synthase (truD),
predicted 5-keto 4-deoxyuronate isomerase monomer (kduI),
FadJ monomer,
peptidyl-prolyl cis-trans isomerase; in protein folding (fkpA),
predicted galactosamine-6-phosphate isomerase (agaI),
putative tagatose-6-phosphate aldose/ketose isomerase (agaS),
KpLE2 phage-like element; predicted epimerase (sgcE),
conserved protein (yeaD),
conserved protein (yddE),
dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC),
predicted L-xylulose 5-phosphate 3-epimerase (sgbU),
probable 4-oxalocrotonate tautomerase (4-OT) monomer (pptA),
UDP-N-acetylglucosamine 2-epimerase (wecB),
phosphomannomutase (cpsG),
glutamate-1-semialdehyde aminotransferase (hemL),
glutamate racemase (murI),
dodecenoyl-CoA δ-isomerase, enoyl-CoA hydratase, 3-hydroxybutyryl-CoA epimerase, 3-hydroxyacyl-CoA dehydrogenase (fadB),
topoisomerase IV subunit B (parE),
topoisomerase IV subunit A (parC),
periplasmic folding chaperone (ppiD),
FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (fklB),
predicted phosphatase (ytjC),
predicted N-acetylmannosamine-6-phosphate epimerase (nanE),
phosphopentomutase (deoB),
predicted racemase (ygeA)

Unification Links: GO:0016853

Relationship Links: ENZYME:RELATED-TO:5

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sat Apr 30, 2016, biocyc14.