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discounted EARLY registration ends Dec 31, 2014
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0016874 - ligase activity

Synonyms: synthetase activity

Definition: Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Parent Classes:
GO:0003824 - catalytic activity

Child Classes:
GO:0008754 - O antigen ligase activity (1) ,
GO:0016875 - ligase activity, forming carbon-oxygen bonds (27) ,
GO:0016877 - ligase activity, forming carbon-sulfur bonds (12) ,
GO:0016879 - ligase activity, forming carbon-nitrogen bonds (44) ,
GO:0016885 - ligase activity, forming carbon-carbon bonds (5) ,
GO:0016886 - ligase activity, forming phosphoric ester bonds (6) ,
GO:0051002 - ligase activity, forming nitrogen-metal bonds (1)

Term Members:
5-formyltetrahydrofolate cyclo-ligase (fau) ,
ribosomal protein S6 modification protein (rimK) ,
tRNA threonylcarbamoyladenosine dehydratase (tcdA) ,
glutamate-putrescine ligase (puuA) ,
propionyl-CoA synthetase (prpE) ,
carboxylate-amine ligase (ybdK) ,
phenylacetate-CoA ligase (paaK) ,
FadD ,
histidyl-tRNA synthetase (hisS) ,
tRNAIle-lysidine synthetase (tilS) ,
RNA ligase (rtcB) ,
RNA 3'-terminal phosphate cyclase (rtcA) ,
short chain acyl-CoA synthetase (fadK) ,
UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminoheptanedioate-D-alanine ligase [multifunctional] (mpl) ,
MenE ,
pantothenate synthetase monomer (panC) ,
carnitine-CoA ligase (caiC) ,
2-acylglycerophosphoethanolamine acyltransferase / acyl-ACP synthetase (aas) ,
acetyl-CoA synthetase (AMP-forming) (acs) ,
O-antigen ligase (waaL) ,
DNA ligase (ligB) ,
AccC ,
UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase (murE) ,
AsnB ,
aspartyl-tRNA synthetase (aspS) ,
cysteinyl-tRNA synthetase (cysS) ,
NadE ,
UDP-N-acetylmuramate-alanine ligase (murC) ,
prolyl-tRNA synthetase (proS) ,
phosphoribosylamine-glycine ligase (purD) ,
phosphoribosylformylglycinamide synthetase (purL) ,
DNA ligase ,
UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (murD) ,
dethiobiotin synthetase monomer (bioD) ,
D-alanyl-D-alanine-adding enzyme (murF) ,
Gss ,
Dfp ,
acetyl-CoA carboxyltransferase, β subunit (accD) ,
GlnA ,
threonyl-tRNA synthetase (thrS) ,
seryl-tRNA synthetase (serS) ,
succinyl-CoA synthetase, β subunit ,
PyrG ,
PurC ,
PurA ,
γ-glutamate-cysteine ligase (gshA) ,
D-alanine-D-alanine ligase A (ddlA) ,
N5-carboxyaminoimidazole ribonucleotide synthetase monomer (purK) ,
bifunctional folylpolyglutamate synthetase / dihydrofolate synthetase (folC) ,
PurM ,
D-alanine-D-alanine ligase B (ddlB) ,
leucyl-tRNA synthetase (leuS) ,
bifunctional biotin-[acetyl-CoA-carboxylase] ligase and transcriptional repressor (birA) ,
glutamyl-tRNA synthetase (gltX) ,
glutathione synthetase monomer (gshB) ,
GMP synthetase (guaA) ,
carbamoyl phosphate synthetase, β chain ,
AsnA ,
glutaminyl-tRNA synthetase (glnS) ,
alanyl-tRNA synthetase (alaS) ,
predicted synthetase/amidase with ATPase activity (yjfC) ,
nicotinate phosphoribosyltransferase (pncB) ,
predicted enzyme with ATPase activity (ygiC) ,
EF-P-lysine lysyltransferase (epmA) ,
asparaginyl-tRNA synthetase (asnS) ,
ArgG ,
7-cyano-7-deazaguanine synthase (queC) ,
Kbl ,
lysyl-tRNA synthetase (lysU) ,
citrate lyase synthetase (citC) ,
2'-5' RNA ligase (ligT) ,
glutamyl-Q tRNAAsp synthetase (gluQ) ,
arginyl-tRNA synthetase (argS) ,
apo-serine activating enzyme (entF) ,
EntE ,
tyrosyl-tRNA synthetase (tyrS) ,
succinyl-CoA synthetase, α subunit (sucD) ,
acetyl-CoA carboxyltransferase, α subunit (accA) ,
lysyl tRNA synthetase (LysRSs), constitutive (lysS) ,
carbamoyl phosphate synthetase, α chain (carA) ,
predicted dethiobiotin synthetase (ynfK) ,
phenylalanyl-tRNA synthetase α-chain (pheS) ,
phenylalanyl-tRNA synthetase β-chain (pheT) ,
valyl-tRNA synthetase (valS) ,
glycyl-tRNA synthetase, β subunit (glyS) ,
glycyl-tRNA synthetase, α subunit (glyQ) ,
methionyl-tRNA synthetase (metG) ,
isoleucyl-tRNA synthetase (ileS) ,
tryptophanyl-tRNA synthetase (trpS)

Unification Links: GO:0016874


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, biocyc14.