Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store
Updated BioCyc iOS App now
available in iTunes store

Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0016874 - ligase activity

Synonyms: synthetase activity

Definition: Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Parent Classes:
GO:0003824 - catalytic activity

Child Classes:
GO:0008754 - O antigen ligase activity (1),
GO:0016875 - ligase activity, forming carbon-oxygen bonds (27),
GO:0016877 - ligase activity, forming carbon-sulfur bonds (17),
GO:0016879 - ligase activity, forming carbon-nitrogen bonds (48),
GO:0016885 - ligase activity, forming carbon-carbon bonds (5),
GO:0016886 - ligase activity, forming phosphoric ester bonds (7),
GO:0051002 - ligase activity, forming nitrogen-metal bonds (1)

Term Members:
EntB monomer,
5-formyltetrahydrofolate cyclo-ligase (fau),
ribosomal protein S6 modification protein (rimK),
tRNA threonylcarbamoyladenosine dehydratase (tcdA),
glutamate-putrescine ligase (puuA),
propionyl-CoA synthetase (prpE),
carboxylate-amine ligase (ybdK),
phenylacetate-CoA ligase (paaK),
histidyl-tRNA synthetase (hisS),
tRNAIle-lysidine synthetase (tilS),
RNA ligase (rtcB),
RNA 3'-terminal phosphate cyclase (rtcA),
short chain acyl-CoA synthetase (fadK),
UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminoheptanedioate-D-alanine ligase [multifunctional] (mpl),
pantothenate synthetase monomer (panC),
carnitine-CoA ligase (caiC),
2-acylglycerophosphoethanolamine acyltransferase / acyl-ACP synthetase (aas),
acetyl-CoA synthetase (AMP-forming) (acs),
O-antigen ligase (waaL),
DNA ligase (ligB),
UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase (murE),
aspartyl-tRNA synthetase (aspS),
cysteinyl-tRNA synthetase (cysS),
UDP-N-acetylmuramate-alanine ligase (murC),
prolyl-tRNA synthetase (proS),
phosphoribosylamine-glycine ligase (purD),
phosphoribosylformylglycinamide synthetase (purL),
DNA ligase,
UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase (murD),
dethiobiotin synthetase monomer (bioD),
D-alanyl-D-alanine-adding enzyme (murF),
acetyl-CoA carboxyltransferase, β subunit (accD),
glutamine synthetase (glnA),
threonyl-tRNA synthetase (thrS),
seryl-tRNA synthetase (serS),
succinyl-CoA synthetase, β subunit,
γ-glutamate-cysteine ligase (gshA),
D-alanine-D-alanine ligase A (ddlA),
N5-carboxyaminoimidazole ribonucleotide synthetase monomer (purK),
bifunctional folylpolyglutamate synthetase / dihydrofolate synthetase (folC),
D-alanine-D-alanine ligase B (ddlB),
leucyl-tRNA synthetase (leuS),
bifunctional biotin-[acetyl-CoA-carboxylase] ligase and transcriptional repressor (birA),
glutamyl-tRNA synthetase (gltX),
glutathione synthetase monomer (gshB),
GMP synthetase (guaA),
carbamoyl phosphate synthetase, β chain,
glutaminyl-tRNA synthetase (glnS),
alanyl-tRNA synthetase (alaS),
predicted synthetase/amidase with ATPase activity (yjfC),
nicotinate phosphoribosyltransferase (pncB),
predicted enzyme with ATPase activity (ygiC),
EF-P-lysine lysyltransferase (epmA),
asparaginyl-tRNA synthetase (asnS),
7-cyano-7-deazaguanine synthase (queC),
lysyl-tRNA synthetase (lysU),
citrate lyase synthetase (citC),
glutamyl-Q tRNAAsp synthetase (gluQ),
arginyl-tRNA synthetase (argS),
apo-serine activating enzyme (entF),
tyrosyl-tRNA synthetase (tyrS),
succinyl-CoA synthetase, α subunit (sucD),
acetyl-CoA carboxyltransferase, α subunit (accA),
lysyl tRNA synthetase (LysRSs), constitutive (lysS),
carbamoyl phosphate synthetase, α chain (carA),
predicted dethiobiotin synthetase (ynfK),
phenylalanyl-tRNA synthetase α-chain (pheS),
phenylalanyl-tRNA synthetase β-chain (pheT),
valyl-tRNA synthetase (valS),
glycyl-tRNA synthetase, β subunit (glyS),
glycyl-tRNA synthetase, α subunit (glyQ),
methionyl-tRNA synthetase (metG),
isoleucyl-tRNA synthetase (ileS),
tryptophanyl-tRNA synthetase (trpS)

Unification Links: GO:0016874

Relationship Links: ENZYME:RELATED-TO:6, Reactome:RELATED-TO:REACT_115603, Reactome:RELATED-TO:REACT_116018

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by Pathway Tools version 19.5 (software by SRI International) on Mon May 2, 2016, biocyc14.