Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0016881 - acid-amino acid ligase activity

Synonyms: peptide synthase activity

Definition: Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.

Parent Classes:
GO:0016879 - ligase activity, forming carbon-nitrogen bonds

Child Classes:
GO:0004326 - tetrahydrofolylpolyglutamate synthase activity (2),
GO:0004357 - glutamate-cysteine ligase activity (2),
GO:0004363 - glutathione synthase activity (1),
GO:0004592 - pantoate-beta-alanine ligase activity (1),
GO:0004632 - phosphopantothenate--cysteine ligase activity (1),
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (3),
GO:0008716 - D-alanine-D-alanine ligase activity (2),
GO:0008763 - UDP-N-acetylmuramate-L-alanine ligase activity (1),
GO:0008764 - UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (1),
GO:0008765 - UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (1),
GO:0008766 - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (1),
GO:0008841 - dihydrofolate synthase activity (1),
GO:0047480 - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity (1),
GO:0047527 - 2,3-dihydroxybenzoate-serine ligase activity (3),
GO:0051108 - carnitine-CoA ligase activity (1),
GO:0070739 - protein-glutamic acid ligase activity (1)

Term Members:
UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase (murE),
UDP-N-acetylmuramate:L-alanyl-γ-D-glutamyl-meso-diaminoheptanedioate-D-alanine ligase [multifunctional] (mpl)

Unification Links: GO:0016881

Relationship Links: ENZYME:RELATED-TO:6.3.2

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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