Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0017148 - negative regulation of translation

Synonyms: GO:0016478, down regulation of protein biosynthetic process, down-regulation of protein biosynthetic process, downregulation of protein biosynthetic process, negative regulation of protein anabolism, negative regulation of protein biosynthesis, negative regulation of protein biosynthetic process, negative regulation of protein formation, negative regulation of protein synthesis

Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.

Parent Classes:
GO:0006417 - regulation of translation,
GO:0010629 - negative regulation of gene expression,
GO:0032269 - negative regulation of cellular protein metabolic process,
GO:0034249 - negative regulation of cellular amide metabolic process,
GO:2000113 - negative regulation of cellular macromolecule biosynthetic process

Child Classes:
GO:0032055 - negative regulation of translation in response to stress (1),
GO:0040033 - negative regulation of translation, ncRNA-mediated (17),
GO:0045900 - negative regulation of translational elongation (2),
GO:0045947 - negative regulation of translational initiation (9),
GO:2000766 - negative regulation of cytoplasmic translation (1)

Term Members:
50S ribosomal subunit protein L25 (rplY),
50S ribosomal subunit protein L4 (rplD),
50S ribosomal subunit protein L20 (rplT),
ribosomal silencing factor (rsfS),
hibernation promoting factor (hpf),
Qin prophage; toxin of the RelE-RelB toxin-antitoxin system and cofactor to enhance the repressor activity of RelB,
30S ribosomal subunit protein S7 (rpsG),
acetyl-CoA carboxyltransferase, β subunit (accD),
acetyl-CoA carboxyltransferase,
translation-dependent mRNA interferase, toxin of the HigB-HigA toxin-antitoxin system,
mRNA interferase, toxin of the MqsR-MqsA toxin-antitoxin system,
ribosome-dependent mRNA interferase, toxin of the YafO-YafN toxin-antitoxin system

Unification Links: GO:0017148

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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