Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0042493 - response to drug

Synonyms: GO:0017035

Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

Parent Classes:
GO:0042221 - response to chemical

GO:0015893 - drug transport (44)

Term Members:
predicted ATP-dependent helicase; implicated in DNA repair (radD),
membrane transport protein; required for proton-motive force (PMF) dependent drug efflux (yqjA),
membrane transport protein; required for proton-motive force (PMF) dependent drug efflux (yghB),
FimZ transcriptional regulator,
AcrAB-TolC multidrug efflux system - permease subunit (acrB),
protein disulfide oxidoreductase - DsbDreduced,
apo-[acyl carrier protein] (acpP),
NlpD divisome associated factor; activates peptidoglycan hydrolase,
flavodoxin NADP+ reductase (fpr),
EnvC divisome associated factor, activator of peptidoglycan hydrolases,
DNA gyrase, subunit B (gyrB),
DNA gyrase, subunit A,
AcrEF-TolC multidrug efflux system - membrane fusion protein,
dihydrofolate reductase,
MicF small regulatory RNA,
penicillin-binding protein 7 (pbpG),
AcrR DNA-binding transcriptional repressor,
vancomycin sensitivity (sanA),
EnvR DNA-binding transcriptional repressor,
cell shape; peptidoglycan synthetase; penicillin-binding protein 2 (mrdA),
essential cell division protein FtsI; penicillin-binding protein 3,
penicillin-binding protein 6 (dacC),
putative transport protein, ABC superfamily (mdlA),
AcrAD-TolC multidrug efflux system - permease subunit (acrD)

Unification Links: GO:0042493

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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