Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0043086 - negative regulation of catalytic activity

Synonyms: down regulation of enzyme activity, down-regulation of enzyme activity, downregulation of enzyme activity, negative regulation of enzyme activity

Definition: Any process that stops or reduces the activity of an enzyme.

Parent Classes:
GO:0050790 - regulation of catalytic activity,
GO:0044092 - negative regulation of molecular function,
GO:0009892 - negative regulation of metabolic process

Child Classes:
GO:0031280 - negative regulation of cyclase activity (1),
GO:0048553 - negative regulation of metalloenzyme activity (3),
GO:0051346 - negative regulation of hydrolase activity (10)

Term Members:
regulator of iron-sulfur cluster assembly (iscX),
AtoC transcriptional activator; Az protein inhibitor of ODC,
DLP12 prophage; periplasmic protein (ybcL),
inhibitor of g-type lysozyme (pliG),
phosphotransferase system enzyme IIA, regulation of potassium transport (ptsN),
chaperone modulator protein CbpM,
inhibitor of c-type lysozyme, predicted lipoprotein (mliC),
ribonuclease E inhibitor protein B (rraB),
ribosome-binding ATPase, inhibitor of catalase activity (ychF),
30S ribosomal subunit protein S20 (rpsT),
SgrT, regulator of PtsG activity,
regulatory protein RecX; inhibitor of RecA,
serine/threonine kinase HipA,
inhibitor of vertebrate C-type lysozyme (ivy)

Unification Links: GO:0043086

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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