Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0043086 - negative regulation of catalytic activity

Synonyms: down regulation of enzyme activity, down-regulation of enzyme activity, downregulation of enzyme activity, negative regulation of enzyme activity

Definition: Any process that stops or reduces the activity of an enzyme.

Parent Classes:
GO:0009892 - negative regulation of metabolic process ,
GO:0044092 - negative regulation of molecular function ,
GO:0050790 - regulation of catalytic activity

Child Classes:
GO:0031280 - negative regulation of cyclase activity (1) ,
GO:0048553 - negative regulation of metalloenzyme activity (3) ,
GO:0051346 - negative regulation of hydrolase activity (12)

Term Members:
AtoC transcriptional activator; Az protein inhibitor of ODC ,
DLP12 prophage; periplasmic protein (ybcL) ,
inhibitor of g-type lysozyme (pliG) ,
phosphotransferase system enzyme IIA, regulation of potassium transport (ptsN) ,
chaperone modulator protein CbpM ,
inhibitor of c-type lysozyme, predicted lipoprotein (mliC) ,
ribonuclease E inhibitor protein B (rraB) ,
ribosome-binding ATPase, inhibitor of catalase activity (ychF) ,
30S ribosomal subunit protein S20 (rpsT) ,
SgrT, regulator of PtsG activity ,
regulatory protein RecX; inhibitor of RecA ,
serine/threonine kinase HipA ,
inhibitor of vertebrate C-type lysozyme (ivy)

Unification Links: GO:0043086

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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