Synonyms: post-translational amino acid modification, post-translational modification, posttranslational amino acid modification, posttranslational modification, posttranslational protein modification, PTM
Definition: The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
GO:0006464 - cellular protein modification process
ribosomal protein-arginine oxygenase (roxA) ,
alkaline phosphatase isozyme conversion protein (iap) ,
EF-P-Lys34 hydroxylase (epmC) ,
lysine 2,3-aminomutase (epmB) ,
EF-P-lysine lysyltransferase (epmA)
Unification Links: GO:0043687
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