Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0043687 - post-translational protein modification

Synonyms: post-translational amino acid modification, post-translational modification, posttranslational amino acid modification, posttranslational modification, posttranslational protein modification, PTM

Definition: The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.

This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.

Parent Classes:
GO:0006464 - cellular protein modification process

Child Classes:
GO:0018410 - C-terminal protein amino acid modification (1) ,
GO:0034421 - post-translational protein acetylation (1)

Term Members:
ribosomal protein-arginine oxygenase (roxA) ,
alkaline phosphatase isozyme conversion protein (iap) ,
EF-P-Lys34 hydroxylase (epmC) ,
lysine 2,3-aminomutase (epmB) ,
EF-P-lysine lysyltransferase (epmA)

Unification Links: GO:0043687

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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