Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0043952 - protein transport by the Sec complex

Definition: The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.

Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial Type II secretion across the outer membrane, consider annotating to 'protein secretion by the Type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.

Parent Classes:
GO:0071806 - protein transmembrane transport

Term Members:
Sec Holo-Translocon,

Unification Links: GO:0043952

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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