Synonyms: dihydrolipoamide S-succinyltransferase complex
Definition: A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:188.8.131.52 (E1), dihydrolipoamide S-succinyltransferase ; EC:184.108.40.206 (E2) and dihydrolipoamide dehydrogenase ; EC:220.127.116.11 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.
GO:0005622 - intracellular
Unification Links: GO:0045252
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493