Escherichia coli K-12 substr. MG1655 Gene-Ontology-Terms Class: GO:0051539 - 4 iron, 4 sulfur cluster binding

Synonyms: 4 Fe 4 S cluster binding, 4 iron, 4 sulphur cluster binding, 4Fe-4S cluster binding, iron-sulfur cluster 4Fe-4S binding, iron-sulphur cluster 4Fe-4S binding, tetrairon tetrasulfide cluster binding, tetrairon tetrasulphide cluster binding

Definition: Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.

Parent Classes:
GO:0051536 - iron-sulfur cluster binding

Term Members:
Fe-S cluster assembly, scaffold protein (sufA),
iron-sulfur cluster assembly protein (iscA),
hydrogenase 2, small subunit (hybO),
nitrate reductase Z, β subunit (narY),
nitrate reductase Z,
fumarate reductase,
tRNA C32 thiolase (ttcA),
colicin M resistance protein (cbrA),
ATP-dependent helicase (dinG),
HypD, scaffold protein for assembly of the Fe-(CN)2CO cofactor,
scaffold protein for iron-sulfur cluster assembly (iscU),
carbon-phosphorus lyase core complex, PhnJ subunit,
predicted oxidoreductase (ydhV),
SufBC2D Fe-S cluster scaffold complex,
HMP-P synthase (thiC),
nitrite reductase, large subunit (nirB),
SufB component of SufBCD Fe-S cluster scaffold complex,
formate dehydrogenase N, α subunit (fdnG),
predicted ATPase, activator of (R)-hydroxyglutaryl-CoA dehdratase (yjiL),
iron-sulfur cluster scaffold protein (nfuA),
conserved protein (ygiQ),
fused predicted oxidoreductase, Fe-S subunit and nucleotide-binding subunit (ygfT),
predicted oxidoreductase, 4Fe-4S ferredoxin-type subunit (ygfS),
predicted oxidoreductase, Fe-S subunit (ygfK),
oxidoreductase subunit (ynfF),
hydrogenase 4, small subunit (hyfI),
member of SoxR-reducing complex (rsxC),
acid resistance protein (ydeP),
predicted amino acid dehydrogenase with NAD(P)-binding domain and ferridoxin-like domain (ykgF),
hydrogenase 4, component H (hyfH),
predicted 4Fe-4S ferredoxin-type protein (ydhX),
oxidoreductase subunit (ynfE),
hydrogenase 4, large subunit (hyfG),
member of SoxR-reducing complex (rsxB),
predicted anaerobic sulfatase maturation enzyme (ydeM),
23S rRNA m5U747 methyltransferase (rlmC),
predicted pyruvate formate lyase activating enzyme (ybiY),
hydrogenase 1, small subunit (hyaA),
putative ferredoxin possibly involved in anaerobic carnitine metabolism (fixX),
conserved protein (queE),
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (ispG),
lipoyl synthase (lipA),
predicted hydrogenase, 4Fe-4S ferredoxin-type component (ysaA),
23S rRNA m5U1939 methyltransferase (rlmD),
pyruvate:flavodoxin oxidoreductase (ydbK),
predicted 4Fe-4S membrane protein (yccM),
predicted 4Fe-4S cluster-containing protein (yfhL),
glycolate oxidase, predicted iron-sulfur subunit (glcF),
predicted oxidoreductase (yggW),
L-serine deaminase III (tdcG),
2,4-dienoyl-CoA reductase (fadH),
predicted pyruvate formate lyase activating enzyme (yjjW),
epoxyqueuosine reductase (queG),
lysine 2,3-aminomutase (epmB),
putative oxidoreductase, Fe-S subunit (aegA),
23S rRNA m2A2503 methyltransferase and tRNA m2A37 methyltransferase (rlmN),
bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase (acnB),
large subunit of periplasmic nitrate reductase, molybdoprotein (napA),
ferredoxin-type protein (napH),
probable pyruvate formate lyase 2 activating enzyme (pflC),
coproporphyrinogen III dehydrogenase (hemN),
molybdopterin biosynthesis protein A (moaA),
L-serine deaminase II (sdaB),
tyrosine lyase (thiH),
NADH-dependent dihydropyrimidine dehydrogenase subunit (preA),
predicted anaerobic sulfatase maturation enzyme (aslB),
aconitate hydratase 1 (acnA),
hydrogenase 4, component A (hyfA),
nitrate reductase Z, α subunit (narZ),
dimethyl sulfoxide reductase, chain B (dmsB),
dimethyl sulfoxide reductase, chain A (dmsA),
sulfite reductase, hemoprotein subunit (cysI),
adenine glycosylase; G.C --> T.A transversions (mutY),
hydrogenase 3 and formate hydrogenlyase complex, HycG subunit,
formate hydrogenlyase complex iron-sulfur protein (hycF),
hydrogenase 3, large subunit (hycE),
L-serine deaminase I (sdaA),
fumarase B monomer (fumB),
nitrate reductase A, β subunit (narH),
ribosomal protein S12 D88 methylthiotransferase (rimO),
isopentenyl-adenosine A37 tRNA methylthiolase (miaB),
fumarate reductase iron-sulfur protein (frdB),
fumarase A monomer,
endonuclease III (nth),
predicted 4Fe-4S ferredoxin-type protein (ydhY),
ferredoxin-type protein (napG),
ferredoxin-type protein (napF),
formate-dependent nitrite reductase, 4Fe-4S subunit (nrfC),
putative electron transport protein HydN,
hydrogenase 3, Fe-S subunit (hycB),
hydrogenase 2 - [Fe-S] binding, ferredoxin-type component HybA,
formate dehydrogenase-O, β subunit (fdoH),
formate dehydrogenase N, β subunit (fdnH),
oxidoreductase, predicted Fe-S subunit (ynfG),
pyruvate formate-lyase activating enzyme (pflA),
YeiL DNA-binding transcriptional activator,
anaerobic glycerol-3-phosphate dehydrogenase subunit C (glpC),
glutamate synthase, small subunit (gltD),
nitrate reductase A, α subunit (narG),
formate dehydrogenase H (fdhF),
succinate:quinone oxidoreductase, iron-sulfur cluster binding protein (sdhB),
L-tartrate dehydratase, α subunit (ttdA),
biotin synthase monomer (bioB),
NADH:ubiquinone oxidoreductase, chain I (nuoI),
NADH:ubiquinone oxidoreductase, chain F (nuoF),
NADH:ubiquinone oxidoreductase, chain B (nuoB),
essential respiratory protein A (erpA),
NADH:ubiquinone oxidoreductase, chain G (nuoG)

Unification Links: GO:0051539

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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