Escherichia coli K-12 substr. MG1655 Compound Class: an L-1-phosphatidylglycerol-phosphate

Synonyms: Phosphatidylglycerophosphate (Ecoli), 3-(3-phosphatidyl)-glycerol 1-phosphate, phosphatidyl-glycerol-phosphate, 3-(3-phosphatidyl)-sn-glycerol 1-phosphate, (3-sn-phosphatidyl)-sn-glycerol 1-phosphate, phosphatidylglycerophosphate, 1-phosphatidyl-glycerol-P, L-1-phosphatidylglycerol-P, 3(3-sn-Phosphatidyl)-sn-glycerol 1-phosphate, 3(3-Phosphatidyl-)L-glycerol 1-phosphate

Superclasses: a lipid a phospholipid a phosphoglyceride

an L-1-phosphatidylglycerol-phosphate compound structure

1,2-dipalmitoyl-phosphatidylglycerol-phosphate ,
phosphatidylglycerophosphate (dihexadec-9-enoyl, n-C16:1) ,
phosphatidylglycerophosphate (dioctadecanoyl, n-C18:0)

SMILES: C(OP([O-])(=O)[O-])C(COP([O-])(=O)OCC(OC(=O)[R2])COC(=O)[R1])O

Unification Links: KEGG:C03892

Reactions known to consume the compound:

cardiolipin biosynthesis I , cardiolipin biosynthesis III :
an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate

Reactions known to produce the compound:

Not in pathways:
an L-1-phosphatidyl-glycerol + ATP → an L-1-phosphatidylglycerol-phosphate + ADP + H+

Reactions known to both consume and produce the compound:

cardiolipin biosynthesis I , cardiolipin biosynthesis III :
a CDP-diacylglycerol + sn-glycerol 3-phosphate ↔ CMP + an L-1-phosphatidylglycerol-phosphate + H+

In Reactions of unknown directionality:

Not in pathways:
a diacylglycerol prolipoprotein[periplasmic space] + a phospholipid[periplasmic space] = murein lipoprotein[periplasmic space] + a lyso-phospholipid[periplasmic space]

Enzymes activated by an L-1-phosphatidylglycerol-phosphate, sorted by the type of activation, are:

Activator (Mechanism unknown) of: malate:quinone oxidoreductase [Narindrasorasak79]

This compound has been characterized as an alternative substrate of the following enzymes: diacylglycerol pyrophosphate phosphatase


Narindrasorasak79: Narindrasorasak S, Goldie AH, Sanwal BD (1979). "Characteristics and regulation of a phospholipid-activated malate oxidase from Escherichia coli." J Biol Chem 1979;254(5);1540-5. PMID: 368072

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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc13.