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Escherichia coli K-12 substr. MG1655 Compound Class: a (3S)-3-hydroxyacyl-CoA

Synonyms: (3S)-3-hydroxyacyl-CoA, 3-hydroxyacyl-CoA, 3-OH-acyl-CoA, RCHOHCH2CO-CoA, trans-3-hydroxyacyl-CoA, (S)-3-hydroxyacyl-CoA, a (S)-3-hydroxyacyl-CoA, a trans-3-hydroxyacyl-CoA, a 3-OH-acyl-CoA, a 3-hydroxyacyl-CoA, an L-3-hydroxyacyl-CoA

Superclasses: an ester a thioester a coenzyme A-activated compound an acyl-CoA a hydroxyacyl-CoA a 3-hydroxyacyl-CoA

Summary:
Acyl-CoAs are oxoacids that have been activated by coenzyme A. They are often classified by the length of their acyl moiety.

Medium-chain acyl-CoAs are derived from fatty acids with aliphatic tails of 6-12 carbons.

Long-chain acyl-CoAs are derived from fatty acids with aliphatic tails of 13-21 carbons.

Very long-chain fatty acyl-CoAs are derived from fatty acids with aliphatic tails of 22 carbons or longer.

a (3<i>S</i>)-3-hydroxyacyl-CoA compound structure

Child Classes: a long-chain (3S)-3-hydroxyacyl-CoA (4) , a medium-chain (3S)-3-hydroxyacyl-CoA (4) , a short-chain (3S)-3-hydroxyacyl-CoA (1) , a very-long-chain (3S)-3-hydroxyacyl-CoA (0)

Component of: FadR-acyl-CoA

SMILES: C([R])C(CC(SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-])=O)O

Unification Links: ChEBI:15455 , KEGG:C00640

Reactions known to consume the compound:

fatty acid β-oxidation I :
a (3S)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+

Not in pathways:
an acyl-CoA + H2O → a carboxylate + coenzyme A + H+

Reactions known to produce the compound:

fatty acid β-oxidation I :
a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O

Reactions known to both consume and produce the compound:

fatty acid β-oxidation I :
a (3R)-3-hydroxyacyl-CoA ↔ a (3S)-3-hydroxyacyl-CoA

In Reactions of unknown directionality:

Not in pathways:
FadR + an acyl-CoA = FadR-acyl-CoA

Transcription Units regulated by related protein FadR-acyl-CoA (1 total):

Transcription-unit diagram


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Mon Aug 31, 2015, biocyc13.