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Metabolic Modeling Tutorial
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Escherichia coli K-12 substr. MG1655 Compound Class: a quinone

Synonyms: quinone

Superclasses: an aldehyde or ketone a ketone a cyclic ketone

Summary:
Quinones are organic compounds derived from aromatic compound, with two carbonyl groups incorporated into the ring structure with rearrangement of the double bonds where necessary. A classic example of a quinone is 1,4-benzoquinone. Quinones are commonly named with a prefix that indicates the parent aromatic hydrocarbon (for example, "benzo-" for benzene, "naphtho-" for naphthalene, and "anthra-" for anthracene) with a "-quinone" suffix.

Several types of quinones serve as electron acceptors in electron transport chains. Quinones can carry two electrons, and when fully reduced they are referred to as quinols. The addition of a single H atom to a quinone results in formation of a free radical called a semiquinone.

Many quinone derivatives often have other biological activities, such as vitamin K.

Child Classes: a glucosyloxyanthraquinone (0) , a hydroxyanthraquinone (0) , a semiquinone (0) , an electron-transfer-related quinone (9) , an unknown quinone (0) , vitamin E (0)

Instances:
5-hydroxy-1,4-naphthoquinone ,
8-hydroxyquinoline-5-sulfonic acid ,
menadione ,
pyrroloquinoline quinone ,
topaquinone

SMILES: C1([R1])(=C([R4])C(=O)C([R3])=C([R2])C(=O)1)

Unification Links: ChEBI:36141 , KEGG:C15602

Reactions known to consume the compound:

TCA cycle I (prokaryotic) :
(S)-malate + a quinone → oxaloacetate + a quinol

Not in pathways:
a quinone + NAD(P)H + H+ → a quinol + NAD(P)+

Reactions known to both consume and produce the compound:

Not in pathways:
a quinone + NADPH ↔ a semiquinone + NADP+

In Reactions of unknown directionality:

Not in pathways:
a quinone + NADH = a semiquinone + NAD+

Inhibits: ArcB sensory histidine kinase[inner membrane] + ATP → ArcB sensory histidine kinase - his292 phosphorylated[inner membrane] + ADP


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Sat Nov 22, 2014, BIOCYC13B.