Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: a primary alcohol + NAD+ ↔ an aldehyde + NADH + H+ ,
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.2: an alcohol + NADP+ = an aldehyde + NADPH + H+ ,
1.1.1.3: L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+ ,
1.1.1.6: glycerol + NAD+ ↔ dihydroxyacetone + NADH + H+ ,
1.1.1.17: D-mannitol 1-phosphate + NAD+ ↔ β-D-fructofuranose 6-phosphate + NADH + H+ ,
1.1.1.22: UDP-α-D-glucose + 2 NAD+ + H2O → UDP-α-D-glucuronate + 2 NADH + 3 H+ ,
1.1.1.25: shikimate + NADP+ ↔ 3-dehydroshikimate + NADPH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.35: a (3S)-3-hydroxyacyl-CoA + NAD+ ↔ a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.35: 3-hydroxyadipyl-CoA + NAD+ ↔ 3-oxoadipyl-CoA + NADH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ → CO2 + pyruvate + NADH ,
1.1.1.38/4.1.1.3: oxaloacetate + H+ → pyruvate + CO2 ,
1.1.1.40: (S)-malate + NADP+ → CO2 + pyruvate + NADPH ,
1.1.1.42: D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.57: D-mannonate + NAD+ ↔ D-fructuronate + NADH + H+ ,
1.1.1.58: D-altronate + NAD+ ↔ D-tagaturonate + NADH + H+ ,
1.1.1.60: D-glycerate + NAD(P)+ ← tartronate semialdehyde + NAD(P)H + H+ ,
1.1.1.61: 4-hydroxybutanoate + NAD+ ↔ succinate semialdehyde + NADH + H+ ,
1.1.1.69: D-gluconate + NAD(P)+ ↔ 5-dehydro-D-gluconate + NAD(P)H + H+ ,
1.1.1.75: (R)-1-aminopropan-2-ol + NAD+ ← aminoacetone + NADH + H+ ,
1.1.1.77: ethylene glycol + NAD+ ↔ glycolaldehyde + NADH + H+ ,
1.1.1.77: (S)-propane-1,2-diol + NAD+ ↔ (S)-lactaldehyde + NADH + H+ ,
1.1.1.79: glycolate + NADP+ ← glyoxylate + NADPH + H+ ,
1.1.1.83: (R)-malate + NAD+ → CO2 + pyruvate + NADH ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ ↔ (S)-2-acetolactate + NADPH + H+ ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+ ,
1.1.1.91: 4-nitrobenzyl alcohol + NADP+ = 4-nitrobenzaldehyde + NADPH + H+ ,
1.1.1.93: L-tartrate + NAD+ = 2-hydroxy-3-oxosuccinate + NADH + H+ ,
1.1.1.94: sn-glycerol 3-phosphate + NAD(P)+ ← dihydroxyacetone phosphate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ ↔ 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.103: L-threonine + NAD+ → 2-amino-3-oxobutanoate + NADH + 2 H+ ,
1.1.1.125: 2-deoxygluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+ ,
1.1.1.127: 2-dehydro-3-deoxy-D-gluconate + NAD+ = 3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H+ ,
1.1.1.130: 3-keto-L-gulonate + NAD+ ← 2,3-dioxo-L-gulonate + NADH + H+ ,
1.1.1.133: dTDP-β-L-rhamnose + NADP+ ← dTDP-4-dehydro-β-L-rhamnose + NADPH + H+ ,
1.1.1.140: D-sorbitol 6-phosphate + NAD+ ↔ D-fructose 6-phosphate + NADH + H+ ,
1.1.1.154: S-ureidoglycolate + NAD(P)+ → oxalurate + NAD(P)H + H+ ,
1.1.1.159: cholate + NAD+ = 3α,12α-dihydroxy-7-oxo-5β-cholan-24-oate + NADH + H+ ,
1.1.1.169: (R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ ,
1.1.1.193: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+ ← 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.211: 3-hydroxy-5-cis-tetradecenoyl-CoA + NAD+ = 3-keto-5-cis-tetradecenoyl-CoA + NADH + H+ ,
1.1.1.215: D-gluconate + NADP+ ← 2-keto-D-gluconate + NADPH + H+ ,
1.1.1.264: L-idonate + NAD(P)+ ↔ 5-dehydro-D-gluconate + NAD(P)H + H+ ,
1.1.1.267: 2-C-methyl-D-erythritol 4-phosphate + NADP+ ↔ 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ ,
1.1.1.271: GDP-β-L-fucose + NADP+ ← GDP-4-dehydro-α-D-rhamnose + NADPH + H+ ,
1.1.1.274: 2-keto-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.276: L-serine + NADP+ = 2-aminomalonate-semialdehyde + NADPH + 2 H+ ,
1.1.1.282: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+ ,
1.1.1.282: shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+ ,
1.1.1.283: (S)-lactaldehyde + NADP+ ← methylglyoxal + NADPH + H+ ,
1.1.1.284: S-hydroxymethylglutathione + NAD(P)+S-formylglutathione + NAD(P)H + H+ ,
1.1.1.290: erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ ,
1.1.1.298: 3-hydroxypropanoate + NADP+ ← malonate semialdehyde + NADPH + H+ ,
1.1.1.305: UDP-α-D-glucuronate + NAD+ → UDP-β-L-threo-pentapyranos-4-ulose + CO2 + NADH ,
1.1.1.336: UDP-N-acetyl-α-D-mannosamine + 2 NAD+ + H2O → UDP-N-acetyl-α-D-mannosaminouronate + 2 NADH + 3 H+ ,
1.1.1.346: 2-keto-L-gulonate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.350: S-ureidoglycolate + NAD+ → oxalurate + NADH + H+ ,
1.1.1.351: D-gluconate 6-phosphate + NAD(P)+ → D-ribulose 5-phosphate + CO2 + NAD(P)H ,
1.1.1.358: (R)-pantolactone + NADP+ ↔ 2-dehydropantolactone + NADPH + H+ ,
1.1.1.373: 2,3-dihydroxypropane 1-sulfonate + NAD+ ← sulfolactaldehyde + NADH + H+ ,
1.1.1.-: dTDP-β-L-rhamnose + NAD+ ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NADH + H+ ,
1.1.1.-: 2-keto-D-gluconate + NADPH + H+ = L-idonate + NADP+ ,
1.1.1.-: 5-dehydro-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.-: isobutanol + NADP+ = isobutanal + NADPH + H+ ,
1.1.1.-: L-idonate + NADP+ ← 2-keto-L-gulonate + NADPH + H+ ,
1.1.1.-: 1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
1.1.1.-: sn-glycerol 3-phosphate + NADP+ ← L-glyceraldehyde 3-phosphate + NADPH + H+ ,
1.1.1.-: D-glycerate + NAD+ ↔ tartronate semialdehyde + NADH + H+ ,
1.1.1.-: methylglyoxal + NADH + H+ = acetol + NAD+ ,
1.1.1.-: acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
1.1.1.-: D-glycerate + NADP+ ← hydroxypyruvate + NADPH + H+ ,
1.1.1.-: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP+ = ethyl-2-methylacetoacetate + NADPH + H+ ,
1.1.1.-: 2-hydroxyglutarate + NAD+ ↔ 2-oxoglutarate + NADH + H+ ,
1.1.1.-: (S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+ ,
1.1.1.-: (R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+ ,
1.1.1.-: 11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD+ ,
1.1.1.-: 2,5-didehydro-D-gluconate + NAD(P)H + H+ = 2-keto-L-gulonate + NAD(P)+ ,
1.1.1.-: galactitol 1-phosphate + NAD+ ↔ D-tagatofuranose 6-phosphate + NADH + H+ ,
1.1.1.-: acetoin + NADP+ = diacetyl + NADPH + H+ ,
1.1.3.-: (S)-2-hydroxyglutarate + oxygen → 2-oxoglutarate + hydrogen peroxide ,
1.1.5.2: β-D-glucose + an ubiquinone = D-glucono-1,5-lactone + an ubiquinol ,
1.1.5.2: D-glucopyranose[periplasmic space] + an ubiquinone[inner membrane] → D-glucono-1,5-lactone[periplasmic space] + an ubiquinol[inner membrane] ,
1.1.5.3: sn-glycerol 3-phosphate + a menaquinone[inner membrane] → dihydroxyacetone phosphate + a menaquinol[inner membrane] ,
1.1.5.3: sn-glycerol 3-phosphate + an ubiquinone[inner membrane] → dihydroxyacetone phosphate + an ubiquinol[inner membrane] ,
1.1.5.4: (S)-malate + a quinone → oxaloacetate + a quinol ,
1.1.5.6: formate[periplasmic space] + a menaquinone[inner membrane] + 2 H+ → CO2[periplasmic space] + a menaquinol[inner membrane] + H+[periplasmic space] ,
1.1.5.-: (R)-lactate + an ubiquinone[inner membrane] → pyruvate + an ubiquinol[inner membrane] ,
1.1.5.-: an aldose[periplasmic space] + an oxidized electron acceptor[periplasmic space] + H2O[periplasmic space] = an aldonate[periplasmic space] + a reduced electron acceptor[periplasmic space] + H+[periplasmic space] ,
1.1.99.1: choline + an oxidized electron acceptor → betaine aldehyde + a reduced electron acceptor ,
1.1.99.14: glycolate + an oxidized electron acceptor → glyoxylate + a reduced electron acceptor ,
1.1.99.33: formate + an oxidized electron acceptor + H+ → CO2 + a reduced electron acceptor ,
1.2.1.4: an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+ ,
1.2.1.4: acetaldehyde + NADP+ + H2O → acetate + NADPH + 2 H+ ,
1.2.1.8: betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ ↔ acetyl-CoA + NADH + H+ ,
1.2.1.11: L-aspartate-semialdehyde + NADP+ + phosphate ↔ L-aspartyl-4-phosphate + NADPH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.19: 4-aminobutanal + NAD+ + H2O → 4-aminobutanoate + NADH + 2 H+ ,
1.2.1.21: glycolaldehyde + NAD+ + H2O → glycolate + NADH + 2 H+ ,
1.2.1.22: (S)-lactaldehyde + NAD+ + H2O → (S)-lactate + NADH + 2 H+ ,
1.2.1.24: succinate semialdehyde + NAD+ + H2O → succinate + NADH + 2 H+ ,
1.2.1.38: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate ↔ N-acetylglutamyl-phosphate + NADPH + H+ ,
1.2.1.39: phenylacetaldehyde + NAD+ + H2O ↔ phenylacetate + NADH + 2 H+ ,
1.2.1.41: L-glutamate-5-semialdehyde + NADP+ + phosphate ← γ-L-glutamyl 5-phosphate + NADPH + H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O → N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.72: D-erythrose 4-phosphate + NAD+ + H2O → erythronate-4-phosphate + NADH + 2 H+ ,
1.2.1.79: succinate semialdehyde + NADP+ + H2O → succinate + NADPH + 2 H+ ,
1.2.1.88: L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+ ,
1.2.1.-: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
1.2.1.-: 3-hydroxypropionaldehyde + NAD+ + H2O → 3-hydroxypropanoate + NADH + 2 H+ ,
1.2.1.-: 4-(γ-glutamylamino)butanal + NAD(P)+ + H2O → 4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ ,
1.2.4.1: pyruvate + lipoamide + H+ = S-acetyldihydrolipoamide + CO2 ,
1.2.5.1: pyruvate + an ubiquinone[inner membrane] + H2O → CO2 + acetate + an ubiquinol[inner membrane] ,
1.2.99.7: an aldehyde[periplasmic space] + FAD[periplasmic space] + H2O[periplasmic space] = a carboxylate[periplasmic space] + FADH2[periplasmic space] ,
1.3.1.1: 5,6-dihydrouracil + NAD+ ↔ uracil + NADH + H+ ,
1.3.1.1: 5,6-dihydrothymine + NAD+ ↔ thymine + NADH + H+ ,
1.3.1.12: prephenate + NAD+ → 4-hydroxyphenylpyruvate + CO2 + NADH ,
1.3.1.28: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ → 2,3-dihydroxybenzoate + NADH + H+ ,
1.3.1.34: trans-Δ2-decenoyl-CoA + NADP+ ← trans-Δ2, cis-Δ4-decadienoyl-CoA + NADPH + H+ ,
1.3.1.38: a 2,3,4-saturated fatty acyl CoA + NADP+ → a trans-2-enoyl-CoA + NADPH + H+ ,
1.3.1.76: precorrin-2 + NAD+ ↔ sirohydrochlorin + NADH + 2 H+ ,
1.3.1.84: propanoyl-CoA + NADP+ = acryloyl-CoA + NADPH + H+ ,
1.3.1.87: 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ → 3-(2,3-dihydroxyphenyl)propanoate + NADH + H+ ,
1.3.1.87: (2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ → 2,3-dihydroxy-trans-cinnamate + NADH + H+ ,
1.3.1.98: UDP-N-α-D-acetylmuramate + NADP+ ← UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+ ,
1.3.1.-: N-ethylmaleimide + NADPH + H+ → N-ethylsuccinimide + NADP+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.5.1: succinate + an ubiquinone[inner membrane] → fumarate + an ubiquinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an ubiquinone[inner membrane] → orotate + an ubiquinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + a menaquinone[inner membrane] → orotate + a menaquinol[inner membrane] ,
1.3.5.3: protoporphyrinogen IX + 3 a menaquinone → protoporphyrin IX + 3 a menaquinol ,
1.3.5.4: fumarate + a menaquinol[inner membrane] ↔ succinate + a menaquinone[inner membrane] ,
1.3.8.4: isovaleryl-CoA + an oxidized electron-transfer flavoprotein = 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.-: a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+ → a trans-2-enoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.99.22: coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine ,
1.3.99.-: γ-butyrobetainyl-CoA + an oxidized electron acceptor ← crotonobetainyl-CoA + a reduced electron acceptor ,
1.4.1.4: L-glutamate + NADP+ + H2O ↔ ammonium + 2-oxoglutarate + NADPH + H+ ,
1.4.1.13: 2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+ ,
1.4.3.5: pyridoxamine 5'-phosphate + oxygen + H2O → ammonium + hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.16: L-aspartate + oxygen → hydrogen peroxide + α-iminosuccinate + H+ ,
1.4.3.21: aminoacetone[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → methylglyoxal[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: an aliphatic amine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → an aldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: 2-phenylethylamine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → phenylacetaldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: a primary amine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → an aldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.5.1: a D-amino acid + an electron-transfer-related quinone[inner membrane] + H2O → ammonium + a 2-oxo carboxylate + an electron-transfer-related quinol[inner membrane] ,
1.4.5.-: D-alanine + an electron-transfer-related quinone[inner membrane] + H2O → ammonium + pyruvate + an electron-transfer-related quinol[inner membrane] ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: a tetrahydrofolate + NADP+ ← a 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.20: an N5-methyl-tetrahydrofolate + NAD+ ↔ a 5,10-methylene-tetrahydrofolate + NADH + H+ ,
1.5.1.30: reduced riboflavin + NADP+ ← riboflavin + NADPH + 2 H+ ,
1.5.1.34: a 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H+ ,
1.5.1.38: NADP+ + FMNH2 ← NADPH + FMN + 2 H+ ,
1.5.1.39: FMNH2 + NAD(P)+ ↔ FMN + NAD(P)H + 2 H+ ,
1.5.1.41: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+ ,
1.5.1.-: tetrahydromonapterin + NADP+ ← 7,8-dihydromonapterin + NADPH + H+ ,
1.5.3.2: N-methyl-L-tryptophan + oxygen + H2O → L-tryptophan + hydrogen peroxide + formaldehyde ,
1.5.5.2: L-proline + an ubiquinone[inner membrane] → (S)-1-pyrroline-5-carboxylate + an ubiquinol[inner membrane] + H+ ,
1.5.99.-: L-aspartate + fumarate → α-iminosuccinate + succinate + H+ ,
1.6.1.2/1.6.1.3: NADPH + NAD+ ↔ NADH + NADP+ ,
1.6.1.2: NADH + NADP+ + H+[periplasmic space] → NADPH + NAD+ + H+[cytosol] ,
1.6.5.2: a quinone + NAD(P)H + H+ → a quinol + NAD(P)+ ,
1.6.5.3: NADH + an ubiquinone[inner membrane] + 5 H+ ↔ NAD+ + an ubiquinol[inner membrane] + 4 H+[periplasmic space] ,
1.6.5.5: a quinone + NADPH ↔ a semiquinone + NADP+ ,
1.6.5.9: NADH + an ubiquinone[inner membrane] + H+ → NAD+ + an ubiquinol[inner membrane] ,
1.6.5.10: NADPH + an electron-transfer-related quinone + H+ → NADP+ + an electron-transfer-related quinol ,
1.6.5.-: NADH + a menaquinone[inner membrane] + 5 H+ → NAD+ + a menaquinol[inner membrane] + 4 H+[periplasmic space] ,
1.6.5.-: a quinone + NADH = a semiquinone + NAD+ ,
1.6.5.-: methyl-1,4-benzoquinone + NADPH + 3 H+ = methyl-1,4-benzoquinol + NADP+ ,
1.6.6.9: trimethylamine N-oxide + NADH + 2 H+ → trimethylamine + NAD+ + H2O ,
1.6.99.5: menadione + NADH + H+ = menadiol + NAD+ ,
1.7.1.7: ammonium + IMP + NADP+ ← GMP + NADPH + 2 H+ ,
1.7.1.13: preQ1 + 2 NADP+ ← preQ0 + 2 NADPH + 3 H+ ,
1.7.1.15: ammonium + 3 NAD+ + 2 H2O ← nitrite + 3 NADH + 5 H+ ,
1.7.1.-: methyl red + 2 NADH + 2 H+ = anthranilate + N,N'-dimethyl-p-phenylenediamine + 2 NAD+ ,
1.7.1.-: an oxidized nitroaromatic compound + NAD(P)H → a reduced nitroaromatic compound + NAD(P)+ ,
1.7.2.3: trimethylamine N-oxide[periplasmic space] + a menaquinol[inner membrane] + H+[periplasmic space] → trimethylamine[periplasmic space] + a menaquinone[inner membrane] + H2O[periplasmic space] ,
1.7.2.-: 2 a reduced c-type cytochrome[out] + nitrate[in] + 2 H+[in] ← 2 an oxidized c-type cytochrome[out] + nitrite[in] + H2O[in] ,
1.7.5.1: nitrate + a menaquinol[inner membrane] + 2 H+ → nitrite + a menaquinone[inner membrane] + H2O + 2 H+[periplasmic space] ,
1.7.99.1: ammonium + an oxidized electron acceptor + H2O ← hydroxylamine + a reduced electron acceptor + H+ ,
1.7.99.4: nitrate[periplasmic space] + an ubiquinol[inner membrane] → nitrite[periplasmic space] + an ubiquinone[inner membrane] + H2O[periplasmic space] ,
1.8.1.2: hydrogen sulfide + 3 NADP+ + 3 H2O ← sulfite + 3 NADPH + 5 H+ ,
1.8.1.7: 2 glutathione + NADP+ ← glutathione disulfide + NADPH + H+ ,
1.8.1.-: an alcohol + NAD+ + H2O ← an organic hydroperoxide + NADH + H+ ,
1.8.4.4: L-cystine + 2 glutathione = glutathione disulfide + 2 L-cysteine ,
1.8.4.4: D-cystine + 2 glutathione = glutathione disulfide + 2 D-cysteine ,
1.8.5.3: dimethyl sulfoxide[periplasmic space] + a menaquinol[inner membrane] → dimethyl sulfide[periplasmic space] + a menaquinone[inner membrane] + H2O[periplasmic space] ,
1.10.3.10: 2 an ubiquinol[inner membrane] + 8 H+ + oxygen → 2 an ubiquinone[inner membrane] + 2 H2O + 8 H+[periplasmic space] ,
1.10.3.14: 2 an ubiquinol[inner membrane] + oxygen + 4 H+ → 2 an ubiquinone[inner membrane] + 2 H2O + 4 H+[periplasmic space] ,
1.11.1.7: a phenolic donor + hydrogen peroxide = 2 a phenoxyl radical of a phenolic donor + 2 H2O ,
1.11.1.9: hydrogen peroxide + 2 glutathione → glutathione disulfide + 2 H2O ,
1.11.1.11: 2 L-ascorbate + hydrogen peroxide + H+ → L-ascorbate + L-dehydro-ascorbate + 2 H2O ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.11.1.21: hydrogen peroxide + a reduced electron acceptor → an oxidized electron acceptor + 2 H2O ,
1.12.99.6: a menaquinone[inner membrane] + 2 H+ + H2[periplasmic space] → a menaquinol[inner membrane] + 2 H+[periplasmic space] ,
1.13.11.16: 3-(2,3-dihydroxyphenyl)propanoate + oxygen → (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H+ ,
1.13.11.16: 2,3-dihydroxy-trans-cinnamate + oxygen → (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H+ ,
1.13.11.24: quercetin + oxygen → 2-protocatechuoylphloroglucinolcarboxylate + carbon monoxide ,
1.14.11.17: taurine + 2-oxoglutarate + oxygen → aminoacetaldehyde + sulfite + succinate + CO2 + H+ ,
1.14.11.33: a methylated nucleobase within DNA + 2-oxoglutarate + oxygen → a nucleobase within DNA + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: N1-methyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + formaldehyde + succinate ,
1.14.11.33: N3-methylcytosine + 2-oxoglutarate + oxygen → cytosine + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: 1-ethyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + acetaldehyde + succinate ,
1.14.11.-: a [50S ribosomal subunit protein L16]-L-arginine81 + 2-oxoglutarate + oxygen → a [50S ribosomal subunit protein L16]-(3R)-3-hydroxy-L-arginine81 + succinate + CO2 ,
1.14.12.17: 2 nitric oxide + NAD(P)H + 2 oxygen → 2 nitrate + NAD(P)+ + H+ ,
1.14.12.19: 3-phenylpropanoate + NADH + oxygen + H+ → 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ ,
1.14.12.19: trans-cinnamate + NADH + oxygen + H+ → (2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ ,
1.14.13.127: 3-(3-hydroxyphenyl)propionate + NADH + H+ + oxygen → 3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O ,
1.14.13.127: 3-hydroxy-trans-cinnamate + NADH + oxygen + H+ → 2,3-dihydroxy-trans-cinnamate + NAD+ + H2O ,
1.14.13.149: phenylacetyl-CoA + NADPH + oxygen + H+ → 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O ,
1.14.13.-: a [protein chain elongation factor EF-P]-L-lysine34 + NADPH + oxygen + H+ → a [protein chain elongation factor EF-P]-5-hydroxy-L-lysine34 + NADP+ + H2O ,
1.14.13.-: 2-octaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-octaprenyl)benzene-1,2-diol + NADP+ + H2O ,
1.14.13.-: 2-methoxy-6-(all-trans-octaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
1.14.14.5: isethionate + FMNH2 + oxygen → glycolaldehyde + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: 3-(N-morpholino)propanesulfonate + FMNH2 + oxygen → 3-(N-morpholino)propanal + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: an alkanesulfonate + FMNH2 + oxygen → an aldehyde + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: 1-butanesulfonate + FMNH2 + oxygen → butanal + sulfite + FMN + H2O + 2 H+ ,
1.14.99.46: thymine + FMNH2 + oxygen → (Z)-2-methylureidoacrylate peracid + FMN + H+ ,
1.14.99.46: uracil + FMNH2 + oxygen → (Z)-3-ureidoacrylate peracid + FMN + H+ ,
1.14.-.-: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + a reduced electron acceptor + oxygen → 3-demethylubiquinol-8 + an oxidized electron acceptor + H2O ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.16.1.9: 2 Fe2+ + 2 a siderophore + NADP+ + H+ ← 2 an Fe(III)-siderophore + NADPH ,
1.16.1.9: 2 Fe2+ + 2 (2,3-dihydroxybenzoylserine)3 + NADP+ ← 2 ferric (2,3-dihydroxybenzoylserine)3 + NADPH + 9 H+ ,
1.16.1.-: Cu2+ + NADH = Cu+ + NAD+ + H+ ,
1.16.3.1: 4 Fe2+ + 4 H+ + oxygen → 4 Fe3+ + 2 H2O ,
1.16.3.2: 4 Fe2+ + oxygen + 6 H2O = 4 [FeO(OH)] monomer + 8 H+ ,
1.16.3.-: 4 Cu+[periplasmic space] + 4 H+[periplasmic space] + oxygen[periplasmic space] → 4 Cu2+[periplasmic space] + 2 H2O[periplasmic space] ,
1.17.1.2: isopentenyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.2: dimethylallyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.4: hypoxanthine + NAD+ + H2O → xanthine + NADH + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.1.7: 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde + NADP+ + H2O → 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H+ ,
1.17.1.8: (S)-2,3,4,5-tetrahydrodipicolinate + NADP+ + H2O ← (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ ,
1.17.1.-: 2-oxepin-2(3H)-ylideneacetyl-CoA + NADP+ + 2 H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H+ ,
1.17.7.-: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + an oxidized flavodoxin + H2O + H+ ← 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + a reduced flavodoxin ,
1.97.1.9: selenite + an oxidized electron acceptor + H2O ← selenate + a reduced electron acceptor ,
1.97.1.-: tellurite + a reduced electron acceptor → Te0 + an oxidized electron acceptor ,
1.97.1.-: S-adenosyl-L-methionine + an inactive ribonucleoside triphosphate reductase ↔ 5'-deoxyadenosine + an active ribonucleoside triphosphate reductase + L-methionine ,
1.-.-.-: d-biotin d-sulfoxide + a reduced thioredoxin = biotin + an oxidized thioredoxin + H2O ,
1.-.-.-: an oxidized nitroaromatic compound + NADPH = a reduced nitroaromatic compound + NADP+ ,
2.1.1.10: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+ ,
2.1.1.13: L-homocysteine + an N5-methyl-tetrahydrofolate → L-methionine + a tetrahydrofolate ,
2.1.1.14: L-homocysteine + N5-methyl--tetrahydropteroyl tri-L-glutamate → L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.45: a 5,10-methylene-tetrahydrofolate + dUMP → dTMP + a 7,8-dihydrofolate ,
2.1.1.64: S-adenosyl-L-methionine + 3-demethylubiquinol-8S-adenosyl-L-homocysteine + ubiquinol-8 + H+ ,
2.1.1.77: S-adenosyl-L-methionine + a [protein]-L-β-isoaspartate → S-adenosyl-L-homocysteine + a protein L-β-isoaspartate α-methyl ester ,
2.1.1.79: a phospholipid olefinic fatty acid + S-adenosyl-L-methionine → a phospholipid cyclopropane fatty acid + S-adenosyl-L-homocysteine + H+ ,
2.1.1.144: trans-aconitate + S-adenosyl-L-methionine → (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine ,
2.1.1.163: S-adenosyl-L-methionine + demethylmenaquinol-8 → S-adenosyl-L-homocysteine + menaquinol-8 + H+ ,
2.1.1.197: a malonyl-[acp] + S-adenosyl-L-methionine → a malonyl-[acp] methyl ester + S-adenosyl-L-homocysteine ,
2.1.1.201: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine → 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.242: a guanine1516 in 16S rRNA + S-adenosyl-L-methionine → an N2-methylguanine1516 in 16S rRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.264: guanine2069 in 23S rRNA + S-adenosyl-L-methionine → N7-methylguanine2069 in 23S rRNA + S-adenosyl-L-homocysteine ,
2.1.1.265: tellurite + S-adenosyl-L-methionine → methanetelluronate + S-adenosyl-L-homocysteine ,
2.1.1.266: adenine2030 in 23S rRNA + S-adenosyl-L-methionine → N6-methyladenine2030 in 23S rRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.297: a [release factor]-L-glutamine + S-adenosyl-L-methionine → a [release factor]-N5-methyl-L-glutamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.298: a [ribosomal protein L3]-L-glutamine + S-adenosyl-L-methionine → a [ribosomal protein L3]-N5-methyl-L-glutamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-methionine → N6-methyl-threonylcarbamoyladenosine 37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl acceptor → S-adenosyl-L-homocysteine + a methylated methyl acceptor + H+ ,
2.1.1.-: L-homocysteine + S-adenosyl-L-methionine → L-methionine + S-adenosyl-L-homocysteine + H+ ,
2.1.2.1: L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O ,
2.1.2.2: an N10-formyl-tetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide ↔ a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ ,
2.1.2.3: an N10-formyl-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ↔ a tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
2.1.2.11: a 5,10-methylene-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O ↔ 2-dehydropantoate + a tetrahydrofolate ,
2.1.2.13: UDP-4-amino-4-deoxy-β-L-arabinopyranose + an N10-formyl-tetrahydrofolate → UDP-4-deoxy-4-formamido-β-L-arabinopyranose + a tetrahydrofolate + H+ ,
2.1.2.-: N1-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + ADP + phosphate + H+ ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate ↔ L-citrulline + phosphate + H+ ,
2.1.3.5: oxamate + carbamoyl-phosphate ← oxalurate + phosphate ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ↔ D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate ↔ β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate ↔ β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.2.1.6: 2 pyruvate + H+ ↔ (S)-2-acetolactate + CO2 ,
2.2.1.6: pyruvate + 2-oxobutanoate + H+ → (S)-2-aceto-2-hydroxybutanoate + CO2 ,
2.2.1.7: pyruvate + D-glyceraldehyde 3-phosphate + H+ → CO2 + 1-deoxy-D-xylulose 5-phosphate ,
2.2.1.9: isochorismate + 2-oxoglutarate + H+ → 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2 ,
2.3.1.1: L-glutamate + acetyl-CoA ↔ N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.1: L-methionine + acetyl-CoA = N-α-acetyl-L-methionine + coenzyme A + H+ ,
2.3.1.5: an arylamine + acetyl-CoA = an N-acetylarylamine + coenzyme A ,
2.3.1.8: acetyl-CoA + phosphate ↔ acetyl phosphate + coenzyme A ,
2.3.1.9: 2 acetyl-CoA ↔ acetoacetyl-CoA + coenzyme A ,
2.3.1.12: acetyl-CoA + dihydrolipoamide = S-acetyldihydrolipoamide + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.16: a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ↔ a 3-oxoacyl-CoA + coenzyme A ,
2.3.1.16: 3-cis-dodecenoyl-CoA + acetyl-CoA = 3-keto-5-cis-tetradecenoyl-CoA + coenzyme A ,
2.3.1.18: a β-D-galactoside + acetyl-CoA ↔ a 6-acetyl-β-D-galactoside + coenzyme A ,
2.3.1.29: glycine + acetyl-CoA ↔ 2-amino-3-oxobutanoate + coenzyme A + H+ ,
2.3.1.30: L-serine + acetyl-CoA ↔ O-acetyl-L-serine + coenzyme A ,
2.3.1.46: L-homoserine + succinyl-CoA → O-succinyl-L-homoserine + coenzyme A ,
2.3.1.47: L-alanine + pimeloyl-CoA + H+ → CO2 + 8-amino-7-oxononanoate + coenzyme A ,
2.3.1.47: a pimeloyl-[acp] + L-alanine + H+ → 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein] ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.54: formate + acetyl-CoA ← pyruvate + coenzyme A ,
2.3.1.57: an aliphatic α,ω-diamine + acetyl-CoA = an aliphatic N-acetyl-diamine + coenzyme A + H+ ,
2.3.1.57: acetyl-CoA + spermidine → N1-acetylspermidine + coenzyme A + H+ ,
2.3.1.79: maltose + acetyl-CoA ↔ acetylmaltose + coenzyme A ,
2.3.1.109: L-arginine + succinyl-CoA → N2-succinyl-L-arginine + coenzyme A + H+ ,
2.3.1.117: (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O → N-succinyl-2-amino-6-ketopimelate + coenzyme A ,
2.3.1.118: an N-hydroxy-arylamine + acetyl-CoA = an N-acetoxyarylamine + coenzyme A ,
2.3.1.157: D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ ,
2.3.1.174: succinyl-CoA + acetyl-CoA ← 3-oxoadipyl-CoA + coenzyme A ,
2.3.1.210: dTDP-thomosamine + acetyl-CoA → dTDP-N-acetylthomosamine + coenzyme A + H+ ,
2.3.1.222: propanoyl-CoA + phosphate → propanoyl phosphate + coenzyme A ,
2.3.1.223: 2,3-didehydroadipyl-CoA + acetyl-CoA ← 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A ,
2.3.1.-: 2-oxobutanoate + coenzyme A → propanoyl-CoA + formate ,
2.3.3.5: oxaloacetate + propanoyl-CoA + H2O → (2S,3S)-2-methylcitrate + coenzyme A + H+ ,
2.3.3.9: acetyl-CoA + glyoxylate + H2O → (S)-malate + coenzyme A + H+ ,
2.3.3.11: propanoyl-CoA + glyoxylate + H2O ↔ 2-hydroxyglutarate + coenzyme A + H+ ,
2.3.3.13: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+ ,
2.3.3.16: oxaloacetate + acetyl-CoA + H2O → citrate + coenzyme A + H+ ,
2.4.1.1: a glycogen + phosphate → a limit dextrin + α-D-glucose 1-phosphate ,
2.4.1.1: maltopentaose + phosphate = α-D-glucose 1-phosphate + maltotetraose ,
2.4.1.1: maltohexaose + phosphate = maltopentaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltoheptaose + phosphate = maltohexaose + α-D-glucose 1-phosphate ,
2.4.1.1: maltotetraose + phosphate ↔ maltotriose + α-D-glucose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate ↔ (1,4-α-D-glucosyl)(n-1) + α-D-glucose 1-phosphate ,
2.4.1.12: UDP-α-D-glucose + cellulose(n) = cellulose(n+1) + UDP ,
2.4.1.15: UDP-α-D-glucose + α-D-glucose 6-phosphate → UDP + α,α-trehalose 6-phosphate + H+ ,
2.4.1.17: UDP-α-D-glucuronate + glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate → UDP + glucosyl-(heptosyl)3-glucuronosyl-Kdo2-lipid A-phosphate ,
2.4.1.18: a 1,4-α-D-glucan ↔ a glycogen ,
2.4.1.21: (1,4-α-D-glucosyl)(n) + ADP-α-D-glucose ↔ ADP + (1,4-α-D-glucosyl)(n+1) ,
2.4.1.25: maltotetraose + D-glucopyranose ← maltotriose + maltose ,
2.4.1.25: maltopentaose + D-glucopyranose = maltotetraose + maltose ,
2.4.1.25: maltohexaose + β-D-glucose = maltopentaose + maltose ,
2.4.1.44: UDP-α-D-galactose + glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.56: a lipopolysaccharide + UDP-N-acetyl-α-D-glucosamine = a N-acetyl-α-D-glucosaminyl-lipopolysaccharide + UDP ,
2.4.1.58: UDP-α-D-glucose + a lipopolysaccharide = a D-glucosyl-lipopolysaccharide + UDP ,
2.4.1.58: UDP-α-D-glucose + galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.73: UDP-α-D-glucose + galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-pentapeptide]n-diphosphoundecaprenol + a lipid II → [GlcNAc-(1->4)-MurNAc-pentapeptide](n+1)-diphosphoundecaprenol + di-trans,octa-cis-undecaprenyl diphosphate ,
2.4.1.129: 2 ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[periplasmic space] → a peptidoglycan dimer (meso-diaminopimelate containing)[periplasmic space] + di-trans,octa-cis-undecaprenyl diphosphate[periplasmic space] + H+[periplasmic space] ,
2.4.1.180: N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP-N-acetyl-α-D-mannosaminouronate → N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP + H+ ,
2.4.1.182: 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+ ,
2.4.1.227: undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-α-D-glucosamine ↔ ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+ ,
2.4.1.325: N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP-N-acetylthomosamine → N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP + H+ ,
2.4.1.-: octyl α-D-glucopyranoside + UDP-α-D-galactofuranose = octyl β-1,6-D-galactofuranosyl-α-D-glucopyranoside + UDP + H+ ,
2.4.1.-: UDP-α-D-glucose + (heptosyl)2-Kdo2-lipid A → glucosyl-(heptosyl)2-Kdo2-lipid A + UDP + H+ ,
2.4.2.1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine ,
2.4.2.1: 2'-deoxyadenosine + phosphate ↔ adenine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine ,
2.4.2.1: a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.2/2.4.2.4: thymidine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + thymine ,
2.4.2.2/2.4.2.3: uridine + phosphate ↔ α-D-ribose-1-phosphate + uracil ,
2.4.2.3: 2'-deoxyuridine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + uracil ,
2.4.2.7: AMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + adenine ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine ,
2.4.2.9: UMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ↔ 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine ,
2.4.2.17: 1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ↔ ATP + 5-phospho-α-D-ribose 1-diphosphate + H+ ,
2.4.2.18: N-(5-phosphoribosyl)-anthranilate + diphosphate ← anthranilate + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.21: β-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole → nicotinate + α-ribazole 5'-phosphate + H+ ,
2.4.2.22: XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.43: (KDO)2-lipid A[periplasmic space] + 2 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[periplasmic space] → 4'-α-L-Ara4N-α-Kdo-(2→4)-α-Kdo-(2→6)-[P4'-α-L-ara4N]-lipid A[periplasmic space] + 2 di-trans,octa-cis-undecaprenyl phosphate[periplasmic space] ,
2.4.2.52: 3'-dephospho-CoA + ATP + H+ → 2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA + adenine ,
2.4.2.53: UDP-4-deoxy-4-formamido-β-L-arabinopyranose + di-trans,octa-cis-undecaprenyl phosphate → 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + UDP ,
2.4.2.-: nicotinamide + α-D-ribose-1-phosphate + H+ = 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
2.4.2.-: phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+ ,
2.4.99.12: CMP-3-deoxy-D-manno-octulosonate + lipid IVA → α-Kdo-(2→6)-lipid IVA + CMP + H+ ,
2.4.99.13: α-Kdo-(2→6)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate → α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + CMP + H+ ,
2.4.-.-: galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate + ADP-L-glycero-β-D-manno-heptose → lipid A-core + ADP + H+ ,
2.4.-.-: glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate + ADP-L-glycero-β-D-manno-heptose → glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate + ADP + H+ ,
2.4.-.-: (KDO)2-lipid A + ADP-L-glycero-β-D-manno-heptose → heptosyl-Kdo2-lipid A + ADP + H+ ,
2.5.1.1: dimethylallyl diphosphate + isopentenyl diphosphate → geranyl diphosphate + diphosphate ,
2.5.1.3: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.3: 4-methyl-5-(2-phosphonooxyethyl)thiazole + 4-amino-2-methyl-5-diphosphomethylpyrimidine + H+ → thiamin phosphate + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.7: UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate → UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate ,
2.5.1.9: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin ,
2.5.1.10: geranyl diphosphate + isopentenyl diphosphate → (2E,6E)-farnesyl diphosphate + diphosphate ,
2.5.1.15: 4-aminobenzoate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate → 7,8-dihydropteroate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.17: cobinamide + ATP → adenosylcobinamide + PPPi ,
2.5.1.17: ATP + cob(I)alamin → coenzyme B12 + PPPi ,
2.5.1.18: 1-chloro-2,4-dinitrobenzene + glutathione ↔ 2,4-dinitrophenyl-S-glutathione + chloride + H+ ,
2.5.1.19: shikimate 3-phosphate + phosphoenolpyruvate ↔ 5-enolpyruvyl-shikimate 3-phosphate + phosphate ,
2.5.1.31: (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate ,
2.5.1.39: all-trans-octaprenyl diphosphate + 4-hydroxybenzoate → 3-octaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.47: O-acetyl-L-serine + hydrogen sulfide ↔ L-cysteine + acetate + H+ ,
2.5.1.48: L-cysteine + O-succinyl-L-homoserine → succinate + L-cystathionine + H+ ,
2.5.1.54: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate ,
2.5.1.55: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O → 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + hydroxymethylbilane ,
2.5.1.72: α-iminosuccinate + dihydroxyacetone phosphate → quinolinate + phosphate + 2 H2O ,
2.5.1.74: all-trans-octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate + H+ → CO2 + demethylmenaquinol-8 + diphosphate ,
2.5.1.78: 5-amino-6-(D-ribitylamino)uracil + 1-deoxy-L-glycero-tetrulose 4-phosphate → 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + H+ + 2 H2O ,
2.5.1.90: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate → all-trans-octaprenyl diphosphate + 5 diphosphate ,
2.5.1.-: cadaverine + S-adenosyl 3-(methylthio)propylamine → aminopropylcadaverine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.-: heme b + (2E,6E)-farnesyl diphosphate + H2O ↔ heme o + diphosphate ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ oxaloacetate + L-glutamate ,
2.6.1.2: 2-oxoglutarate + L-alanine ↔ L-glutamate + pyruvate ,
2.6.1.3: 2-oxoglutarate + L-cysteine → L-glutamate + 3-mercaptopyruvate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate ↔ 4-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.7: L-kynurenine + 2-oxoglutarate ↔ L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate ,
2.6.1.9: imidazole acetol-phosphate + L-glutamate → L-histidinol-phosphate + 2-oxoglutarate ,
2.6.1.11: N-acetyl-L-ornithine + 2-oxoglutarate ← N-acetyl-L-glutamate 5-semialdehyde + L-glutamate ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.17: 2-oxoglutarate + N-succinyl-L,L-2,6-diaminopimelate ↔ L-glutamate + N-succinyl-2-amino-6-ketopimelate ,
2.6.1.19: 2-oxoglutarate + 4-aminobutanoate ↔ L-glutamate + succinate semialdehyde ,
2.6.1.29: an aliphatic α,ω-diamine + 2-oxoglutarate ↔ an aliphatic ω-aminoaldehyde + L-glutamate ,
2.6.1.31: pyridoxamine + oxaloacetate ↔ pyridoxal + L-aspartate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate ↔ (S)-3-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.42: L-valine + 2-oxoglutarate ↔ 3-methyl-2-oxobutanoate + L-glutamate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ↔ 3-phospho-hydroxypyruvate + L-glutamate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate ↔ 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.57: an aromatic amino acid + 2-oxoglutarate ↔ an aromatic oxo-acid + L-glutamate ,
2.6.1.57: 2-oxo-3-phenylpropanoate + L-glutamate ↔ L-phenylalanine + 2-oxoglutarate ,
2.6.1.57: L-tyrosine + 2-oxoglutarate ↔ 4-hydroxyphenylpyruvate + L-glutamate ,
2.6.1.59: dTDP-thomosamine + 2-oxoglutarate ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + L-glutamate ,
2.6.1.62: S-adenosyl-L-methionine + 8-amino-7-oxononanoate ↔ S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminopelargonate ,
2.6.1.66: pyruvate + L-valine ↔ L-alanine + 3-methyl-2-oxobutanoate ,
2.6.1.81: N2-succinyl-L-ornithine + 2-oxoglutarate ↔ N2-succinyl-L-glutamate 5-semialdehyde + L-glutamate ,
2.6.1.82: 4-aminobutanal ↔ 1-pyrroline + H2O ,
2.6.1.85: L-glutamine + chorismate ↔ 4-amino-4-deoxychorismate + L-glutamate ,
2.6.1.87: UDP-4-amino-4-deoxy-β-L-arabinopyranose + 2-oxoglutarate ↔ UDP-β-L-threo-pentapyranos-4-ulose + L-glutamate ,
2.6.1.88: L-methionine + a 2-oxo carboxylate = 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.1.-: an aminated amino group acceptor + 2-oxobutanoate = 2-aminobutanoate + a deaminated amino group acceptor ,
2.6.99.2: 3-amino-1-hydroxyacetone 1-phosphate + 1-deoxy-D-xylulose 5-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O ,
2.7.1.2: β-D-glucose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: D-glucopyranose + ATP → D-glucopyranose 6-phosphate + ADP + H+ ,
2.7.1.4: β-D-fructofuranose + ATP → β-D-fructofuranose 6-phosphate + ADP + H+ ,
2.7.1.5: L-rhamnulofuranose + ATP → L-rhamnulose 1-phosphate + ADP + H+ ,
2.7.1.6: α-D-galactose + ATP → α-D-galactose 1-phosphate + ADP + H+ ,
2.7.1.7: D-mannopyranose + ATP → α-D-mannose 6-phosphate + ADP + H+ ,
2.7.1.11: β-D-fructofuranose 6-phosphate + ATP → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.12: ATP + D-gluconate → ADP + D-gluconate 6-phosphate + H+ ,
2.7.1.15: α-D-ribofuranose + ATP → α-D-ribose 5-phosphate + ADP + H+ ,
2.7.1.16: L-ribulose + ATP → L-ribulose 5-phosphate + ADP + H+ ,
2.7.1.17: D-xylulose + ATP → D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.22: 1-(β-D ribofuranosyl)nicotinamide + ATP → β-nicotinamide D-ribonucleotide + ADP + H+ ,
2.7.1.23: ATP + NAD+ → ADP + NADP+ + H+ ,
2.7.1.24: 3'-dephospho-CoA + ATP → ADP + coenzyme A + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP ↔ 3'-phosphoadenylyl-sulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.31: D-glycerate + ATP → 3-phospho-D-glycerate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → (R)-4'-phosphopantothenate + ADP + H+ ,
2.7.1.35: ATP + pyridoxine → ADP + pyridoxine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxamine → ADP + pyridoxamine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxal → ADP + pyridoxal 5'-phosphate + H+ ,
2.7.1.39: L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ ,
2.7.1.40: pyruvate + ATP ↔ ADP + phosphoenolpyruvate + H+ ,
2.7.1.48: cytidine + GTP → CMP + GDP + H+ ,
2.7.1.48: cytidine + ATP → CMP + ADP + H+ ,
2.7.1.48: uridine + ATP → UMP + ADP + H+ ,
2.7.1.48: uridine + GTP → UMP + GDP + H+ ,
2.7.1.49: ATP + hydroxymethylpyrimidine → ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine + H+ ,
2.7.1.50: ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ ,
2.7.1.51: L-fuculose + ATP → L-fuculose 1-phosphate + ADP + H+ ,
2.7.1.53: L-xylulose + ATP → L-xylulose -5-phosphate + ADP + H+ ,
2.7.1.55: D-allopyranose + ATP → aldehydo-D-allose 6-phosphate + ADP + H+ ,
2.7.1.56: ATP + β-D-fructofuranose 1-phosphate → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.59: N-acetyl-β-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+ ,
2.7.1.60: N-acetyl-D-mannosamine + ATP → N-acetyl-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.69: HPr-Phis15 + galactitol[periplasmic space] → galactitol 1-phosphate[cytosol] + HPr ,
2.7.1.69: 2-deoxy-D-glucose[periplasmic space] + HPr-Phis15 → 2-deoxy-D-glucose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + L-ascorbate[periplasmic space] → L-ascorbate 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + 2-O-α-mannosyl-D-glycerate[periplasmic space] → 2-O-(6-phospho-α-D-mannosyl)-D-glycerate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + D-sorbitol[periplasmic space] → D-sorbitol 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + β-D-glucose[periplasmic space] → β-D-glucose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + α,α-trehalose[periplasmic space] → α,α-trehalose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + salicin[periplasmic space] → salicin 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + N-acetylmuramate[periplasmic space]N-acetyl-β-muramate 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + D-mannitol[periplasmic space] → D-mannitol 1-phosphate[cytosol] + HPr ,
2.7.1.69: D-glucosamine[periplasmic space] + HPr-Phis15 → D-glucosamine 6-phosphate[cytosol] + HPr ,
2.7.1.69: N,N'-diacetylchitobiose[periplasmic space] + HPr-Phis15 → HPr + N,N'-diacetylchitobiose 6'-phosphate[cytosol] ,
2.7.1.71: shikimate + ATP → shikimate 3-phosphate + ADP + H+ ,
2.7.1.73: guanosine + ATP → GMP + ADP + H+ ,
2.7.1.73: inosine + ATP → IMP + ADP + H+ ,
2.7.1.83: pseudouridine + ATP → pseudouridine 5'-phosphate + ADP + H+ ,
2.7.1.89: thiamin + ATP → thiamin phosphate + ADP + H+ ,
2.7.1.107: ATP + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.121: dihydroxyacetone + phosphoenolpyruvate → dihydroxyacetone phosphate + pyruvate ,
2.7.1.130: lipid A disaccharide + ATP → lipid IVA + ADP + H+ ,
2.7.1.144: D-tagatofuranose 6-phosphate + ATP → D-tagatofuranose 1,6-bisphosphate + ADP + H+ ,
2.7.1.145: 2'-deoxyuridine + ATP → dUMP + ADP + H+ ,
2.7.1.145: thymidine + ATP → dTMP + ADP + H+ ,
2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP → 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP + H+ ,
2.7.1.156: adenosylcobinamide + ATP → adenosyl-cobinamide phosphate + ADP + H+ ,
2.7.1.165: ATP + D-glycerate → 2-phospho-D-glycerate + ADP + H+ ,
2.7.1.167: D-glycero-D-manno-heptose 7-phosphate + ATP → D-glycero-β-D-manno-heptose 1,7-bisphosphate + ADP + H+ ,
2.7.1.170: 1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ ,
2.7.1.178: 2-dehydro-3-deoxy-D-galactonate + ATP → 2-dehydro-3-deoxy-D-galactonate 6-phosphate + ADP + H+ ,
2.7.1.178: 2-dehydro-3-deoxy-D-gluconate + ATP → 2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ ,
2.7.1.184: 6-deoxy-6-sulfo-D-fructose + ATP → 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H+ ,
2.7.1.-: 4-hydroxy-L-threonine + ATP → 4-phospho-hydroxy-L-threonine + ADP + H+ ,
2.7.1.-: glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate + ATP → glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate + ADP + H+ ,
2.7.1.-: glucosyl-(heptosyl)2-Kdo2-lipid A + ATP → glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate + ADP + H+ ,
2.7.1.-: ATP + 1-deoxy-D-xylulose → 1-deoxy-D-xylulose 5-phosphate + ADP + H+ ,
2.7.2.1: acetate + ATP ↔ acetyl phosphate + ADP ,
2.7.2.2: ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.4: L-aspartate + ATP → L-aspartyl-4-phosphate + ADP ,
2.7.2.8: N-acetyl-L-glutamate + ATP → N-acetylglutamyl-phosphate + ADP ,
2.7.2.11: L-glutamate + ATP → γ-L-glutamyl 5-phosphate + ADP ,
2.7.2.15: ATP + propanoate ↔ ADP + propanoyl phosphate ,
2.7.4.1: ATP + (polyphosphate)(n) ↔ ADP + (polyphosphate)(n+1) ,
2.7.4.3: AMP + ATP ↔ 2 ADP ,
2.7.4.4: GTP + AMP → GDP + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP → a nucleoside triphosphate + ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.7: 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP → 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP ,
2.7.4.8: GMP + ATP ↔ GDP + ADP ,
2.7.4.12/2.7.4.13: dTMP + ATP → dTDP + ADP ,
2.7.4.13: ATP + dGMP ↔ ADP + dGDP ,
2.7.4.14/2.7.4.25: ATP + CMP ↔ ADP + CDP ,
2.7.4.16: thiamin phosphate + ATP → thiamin diphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.23: α-D-ribose 1,5-bisphosphate + ATP → 5-phospho-α-D-ribose 1-diphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.6.1: D-ribose 5-phosphate + ATP → 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.3: 6-hydroxymethyl-7,8-dihydropterin + ATP → (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + H+ ,
2.7.6.5: ATP + GDP → AMP + ppGpp ,
2.7.6.5: GTP + ATP → pppGpp + AMP ,
2.7.7.1: β-nicotinamide D-ribonucleotide + ATP + H+ → NAD+ + diphosphate ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.3: 4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.9: α-D-glucose 1-phosphate + UTP + H+ → UDP-α-D-glucose + diphosphate ,
2.7.7.12: UDP-α-D-glucose + α-D-galactose 1-phosphate ↔ UDP-α-D-galactose + α-D-glucose 1-phosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.18: ATP + β-nicotinate D-ribonucleotide + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.24: α-D-glucose 1-phosphate + dTTP + H+ ↔ dTDP-α-D-glucose + diphosphate ,
2.7.7.27: α-D-glucose 1-phosphate + ATP + H+ → ADP-α-D-glucose + diphosphate ,
2.7.7.38: 3-deoxy-D-manno-octulosonate + CTP → CMP-3-deoxy-D-manno-octulosonate + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.41: CTP + a 2,3,4-saturated L-phosphatidate + H+ → a CDP-2,3,4-saturated-diacylglycerol + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate → a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.58: ATP + 2,3-dihydroxybenzoate + H+ → 2,3-dihydroxybenzoyl-AMP + diphosphate ,
2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate + CTP + H+ → 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + diphosphate ,
2.7.7.62: adenosyl-cobinamide phosphate + GTP + H+ → adenosylcobinamide-GDP + diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.65: 2 GTP → cyclic di-3',5'-guanylate + 2 diphosphate ,
2.7.7.70: D-glycero-β-D-manno-heptose 1-phosphate + ATP + H+ → ADP-D-glycero-β-D-manno-heptose + diphosphate ,
2.7.7.75: ATP + molybdopterin + H+ → molybdopterin adenine dinucleotide + diphosphate ,
2.7.7.76: MoO2-molybdopterin cofactor + CTP + H+ → cytidylyl molybdenum cofactor + diphosphate ,
2.7.7.77: MoO2-molybdopterin cofactor + GTP + H+ → guanylyl molybdenum cofactor + diphosphate ,
2.7.7.-: thiamin diphosphate + ADP + H+ ↔ adenosine thiamine triphosphate + phosphate ,
2.7.7.-: ATP + ADP + H+ → 5',5'''-diadenosine triphosphate + diphosphate ,
2.7.7.-: ATP + ATP + H+ = 5',5'''-diadenosine tetraphosphate + diphosphate ,
2.7.7.-: an insertion sequence element IS30 = an insertion sequence IS30 with integrated transposon ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.8.5: a CDP-diacylglycerol + sn-glycerol 3-phosphate ↔ CMP + an L-1-phosphatidylglycerol-phosphate + H+ ,
2.7.8.8: a CDP-diacylglycerol + L-serine ↔ CMP + an L-1-phosphatidylserine + H+ ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate ↔ undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP ,
2.7.8.20: an osmoregulated periplasmic glucan[periplasmic space] + an L-1-phosphatidyl-glycerol[periplasmic space] ↔ a 1,2-diacyl-sn-glycerol[periplasmic space] + an OPG-6-(glycerophospho)-D-glucose[periplasmic space] ,
2.7.8.21: an OPG-6-(glycerophospho)-D-glucose[periplasmic space] + an osmoregulated periplasmic glucan[periplasmic space] ↔ an osmoregulated periplasmic glucan[periplasmic space] + an OPG-6-(glycerophospho)-D-glucose[periplasmic space] ,
2.7.8.26: adenosylcobinamide-GDP + α-ribazole 5'-phosphate → adenosylcobalamin 5'-phosphate + GMP + H+ ,
2.7.8.33: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UMP ,
2.7.8.37: methylphosphonate + ATP → α-D-ribose-1-methylphosphonate-5-triphosphate + adenine ,
2.7.8.-: 2 an L-1-phosphatidyl-glycerol → a cardiolipin + glycerol ,
2.7.9.2: pyruvate + ATP + H2O → phosphoenolpyruvate + AMP + phosphate + 2 H+ ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.7.10.2/2.7.12.1: ATP + a [protein]-L-tyrosine → ADP + a [protein]-L-tyrosine phosphate + H+ ,
2.8.1.1: a sulfurated [sulfur carrier] + hydrogen cyanide → an unsulfurated [sulfur carrier] + thiocyanate + H+ ,
2.8.1.1: hydrogen cyanide + thiosulfate → thiocyanate + sulfite + 2 H+ ,
2.8.1.2: hydrogen cyanide + 3-mercaptopyruvate → pyruvate + thiocyanate + H+ ,
2.8.1.6: a sulfurated [sulfur carrier] + dethiobiotin + 2 S-adenosyl-L-methionine → an unsulfurated [sulfur carrier] + biotin + 2 5'-deoxyadenosine + 2 L-methionine ,
2.8.1.7: an [L-cysteine desulfurase] L-cysteine persulfide + an unsulfurated [sulfur carrier] ↔ an [L-cysteine desulfurase]-L-cysteine + a sulfurated [sulfur carrier] ,
2.8.1.7: an [L-cysteine desulfurase] + L-cysteine = an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase]-L-cysteine + L-cysteine → an [L-cysteine desulfurase] L-cysteine persulfide + L-alanine ,
2.8.1.7: L-cysteine + an unsulfurated [sulfur carrier] → L-alanine + a sulfurated [sulfur carrier] ,
2.8.1.12: cyclic pyranopterin phosphate + 2 a thiocarboxylated small subunit of molybdopterin synthase + H2O → 2 a small subunit of molybdopterin synthase + molybdopterin ,
2.8.3.8: a 2,3,4-saturated fatty acyl CoA + acetate ↔ a 2,3,4-saturated fatty acid + acetyl-CoA ,
2.8.3.16: formyl-CoA + oxalate = formate + oxalyl-CoA ,
2.8.3.19: acetyl-CoA + oxalate = oxalyl-CoA + acetate ,
2.8.3.21: L-carnitine + γ-butyrobetainyl-CoA → L-carnitinyl-CoA + γ-butyrobetaine ,
2.8.3.-: propanoyl-CoA + succinate ↔ propanoate + succinyl-CoA ,
2.8.3.-: acetoacetate + acetyl-CoA ↔ acetoacetyl-CoA + acetate ,
2.8.4.3: N6-dimethylallyladenosine37 in tRNA + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier] → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + an unsulfurated [sulfur carrier] + H+ ,
2.10.1.1: molybdopterin adenine dinucleotide + molybdate + H+ → MoO2-molybdopterin cofactor + AMP + H2O ,
2.-.-.-: heptosyl-Kdo2-lipid A + ADP-L-glycero-β-D-manno-heptose → (heptosyl)2-Kdo2-lipid A + ADP + H+ ,
3.1.1.1: a carboxylic ester + H2O → an alcohol + a carboxylate + H+ ,
3.1.1.4: an L-1-phosphatidyl-ethanolamine[periplasmic space] + H2O[periplasmic space] → a fatty acid[periplasmic space] + a 2-lyso-phosphatidyl-ethanolamine[periplasmic space] + H+[periplasmic space] ,
3.1.1.5: a 1-lysophosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.6: an acetic ester + H2O → an alcohol + acetate + H+ ,
3.1.1.17: D-glucono-1,5-lactone + H2O → D-gluconate + H+ ,
3.1.1.25: D-galactono-1,4-lactone + H2O → D-galactonate + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.1.32: an L-1-phosphatidyl-ethanolamine[periplasmic space] + H2O[periplasmic space] → a 1-lyso-2-acyl-sn-glycero-3-phosphoethanolamine[periplasmic space] + a fatty acid[periplasmic space] + H+[periplasmic space] ,
3.1.1.-: ferric enterobactin complex + H2O → ferric (2,3-dihydroxybenzoylserine)3 ,
3.1.1.-: L-ascorbate 6-phosphate + H2O → 3-keto-L-gulonate 6-phosphate ,
3.1.1.-: enterobactin + 3 H2O → 3 N-(2,3-dihydroxybenzoyl)-L-serine + 3 H+ ,
3.1.1.-: (2,3-dihydroxybenzoylserine)2 + H2O → 2 N-(2,3-dihydroxybenzoyl)-L-serine + H+ ,
3.1.1.-: (2,3-dihydroxybenzoylserine)3 + H2O → (2,3-dihydroxybenzoylserine)2 + N-(2,3-dihydroxybenzoyl)-L-serine + H+ ,
3.1.1.-: enterobactin + H2O → (2,3-dihydroxybenzoylserine)3 + H+ ,
3.1.2.2: a 2,3,4-saturated fatty acyl CoA[periplasmic space] + H2O[periplasmic space] → a 2,3,4-saturated fatty acid[periplasmic space] + coenzyme A[periplasmic space] + H+[periplasmic space] ,
3.1.2.6: (R)-S-lactoylglutathione + H2O → glutathione + (R)-lactate + H+ ,
3.1.2.12: S-formylglutathione + H2O → formate + glutathione + H+ ,
3.1.2.16: an acetyl-[holo citrate lyase acyl-carrier protein] + 6 H2O → [a holo citrate lyase acyl-carrier protein] + 6 acetate ,
3.1.2.20: an acyl-CoA + H2O → a carboxylate + coenzyme A + H+ ,
3.1.2.28: 1,4-dihydroxy-2-naphthoyl-CoA + H2O → 1,4-dihydroxy-2-naphthoate + coenzyme A + H+ ,
3.1.2.-: 3-hydroxybenzoyl-CoA + H2O → 3-hydroxybenzoate + coenzyme A + H+ ,
3.1.2.-: 3-trans,5-cis-tetradecadienoyl-CoA + H2O → (3E,5Z)-tetradecadienoate + coenzyme A + H+ ,
3.1.3.1: a phosphate monoester[periplasmic space] + H2O[periplasmic space] ↔ an alcohol[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.2: a phosphate monoester[periplasmic space] + H2O[periplasmic space] ↔ an alcohol[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.5: a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.5: AMP + H2O → adenosine + phosphate ,
3.1.3.5: UMP + H2O → uridine + phosphate ,
3.1.3.5: β-nicotinamide D-ribonucleotide + H2O → 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
3.1.3.5: IMP + H2O → inosine + phosphate ,
3.1.3.5: GMP + H2O → guanosine + phosphate ,
3.1.3.6: a nucleoside 3'-phosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.6: cytidine-3'-monophosphate + H2O → cytidine + phosphate ,
3.1.3.6: uridine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → uridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.6: guanosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.6: adenosine 3'-monophosphate + H2O → adenosine + phosphate ,
3.1.3.7: adenosine 3',5'-bisphosphate + H2O → AMP + phosphate ,
3.1.3.8: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate[periplasmic space] + H2O[periplasmic space] → D-myo-inositol (1,2,4,5,6)-pentakisphosphate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.10: α-D-glucose 1-phosphate + H2O → D-glucopyranose + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.12: α,α-trehalose 6-phosphate + H2O → α,α-trehalose + phosphate ,
3.1.3.15: L-histidinol-phosphate + H2O → histidinol + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.19: glycerol 2-phosphate + H2O → glycerol + phosphate ,
3.1.3.20: 2-phospho-D-glycerate[periplasmic space] + H2O[periplasmic space] → D-glycerate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.21: glycerol 1-phosphate + H2O → glycerol + phosphate ,
3.1.3.23: a sugar phosphate + H2O → a sugar + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.27: an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate ,
3.1.3.34: a 2'-deoxyribonucleoside 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → a 2'-deoxynucleoside[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: thymidine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → thymidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxycytidine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxycytidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxyuridine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyuridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxyadenosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyadenosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxyguanosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyguanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.41: 4-nitrophenyl phosphate[periplasmic space] + H2O[periplasmic space] → 4-nitrophenol[periplasmic space] + phosphate[periplasmic space] + H+[periplasmic space] ,
3.1.3.45: 3-deoxy-D-manno-octulosonate 8-phosphate + H2O → 3-deoxy-D-manno-octulosonate + phosphate ,
3.1.3.58: β-D-glucose 6-phosphate + H2O → β-D-glucose + phosphate ,
3.1.3.58: α-D-glucose 6-phosphate + H2O → α-D-glucose + phosphate ,
3.1.3.58: D-glucopyranose 6-phosphate[periplasmic space] + H2O[periplasmic space] → D-glucopyranose[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.60: phosphoenolpyruvate[periplasmic space] + H2O[periplasmic space] → pyruvate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate[periplasmic space] + H2O[periplasmic space] → D-myo-inositol (1,2,3,4,5)-pentakisphosphate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.68: 2-deoxy-D-glucose 6-phosphate + H2O → 2-deoxy-D-glucose + phosphate ,
3.1.3.73: α-ribazole 5'-phosphate + H2O → α-ribazole + phosphate ,
3.1.3.73: adenosylcobalamin 5'-phosphate + H2O → coenzyme B12 + phosphate ,
3.1.3.74: pyridoxal 5'-phosphate + H2O → pyridoxal + phosphate ,
3.1.3.74: pyridoxine 5'-phosphate[periplasmic space] + H2O[periplasmic space] → pyridoxine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.75: phosphocholine[periplasmic space] + H2O[periplasmic space] → choline[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.75: phosphoryl-ethanolamine[periplasmic space] + H2O[periplasmic space] → ethanolamine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.82: D-glycero-β-D-manno-heptose 1,7-bisphosphate + H2O → D-glycero-β-D-manno-heptose 1-phosphate + phosphate ,
3.1.3.89: dGMP + H2O → 2'-deoxyguanosine + phosphate ,
3.1.3.89: dUMP + H2O → 2'-deoxyuridine + phosphate ,
3.1.3.89: dAMP + H2O → 2'-deoxyadenosine + phosphate ,
3.1.3.89: a 2'-deoxyribonucleoside 5'-monophosphate + H2O → a 2'-deoxynucleoside + phosphate ,
3.1.3.89: dCMP + H2O → 2'-deoxycytidine + phosphate ,
3.1.3.89: dTMP + H2O → thymidine + phosphate ,
3.1.3.91: CMP + H2O → cytidine + phosphate ,
3.1.3.-: FMN + H2O → riboflavin + phosphate ,
3.1.3.-: β-D-fructofuranose 1-phosphate + H2O → β-D-fructofuranose + phosphate ,
3.1.3.-: D-gluconate 6-phosphate + H2O → D-gluconate + phosphate ,
3.1.3.-: NADP+ + H2O → NAD+ + phosphate ,
3.1.3.-: cysteamine S-phosphate[periplasmic space] + H2O[periplasmic space] → cysteamine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: adenosine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → adenosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: guanosine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: cytidine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → cytidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: uridine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → uridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: D-ribose 5-phosphate[periplasmic space] + H2O[periplasmic space]aldehydo-D-ribose[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: L-threonine 3-O-phosphate[periplasmic space] + H2O[periplasmic space] → L-threonine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: a hexose phosphate + H2O = a hexose + phosphate ,
3.1.4.16: a 2',3'-cyclic nucleoside phosphate[periplasmic space] + H2O[periplasmic space] → a nucleoside 3'-phosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: guanosine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: uridine 2'3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → uridine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: cytidine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → cytidine-3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: adenosine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → adenosine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.46: a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+ ,
3.1.4.46: glycerophosphoglycerol + H2O → glycerol + sn-glycerol 3-phosphate + H+ ,
3.1.4.46: glycerophosphoserine + H2O → sn-glycerol 3-phosphate + L-serine + H+ ,
3.1.4.46: sn-glycero-3-phosphoethanolamine + H2O → sn-glycerol 3-phosphate + ethanolamine + H+ ,
3.1.4.52: cyclic di-3',5'-guanylate + H2O → linear dimeric GMP + H+ ,
3.1.4.53: cyclic-AMP + H2O → AMP + H+ ,
3.1.4.55: 5-phospho-α-D-ribose 1,2-cyclic phosphate + H2O → α-D-ribose 1,5-bisphosphate + H+ ,
3.1.5.1: dGTP + H2O → PPPi + 2'-deoxyguanosine + H+ ,
3.1.6.1: a phenol sulfate + H2O ↔ a phenol + sulfate + H+ ,
3.1.6.-: sodium dodecyl sulfate + H2O → 1-dodecanol + sulfate + Na+ + H+ ,
3.1.7.2: ppGpp + H2O → GDP + diphosphate + H+ ,
3.1.7.2: pppGpp + H2O → GTP + diphosphate + H+ ,
3.1.11.1: DNAn + H2O → (deoxynucleotides)(n-1) + a 2'-deoxyribonucleoside 5'-monophosphate ,
3.1.11.6: a single stranded DNA + H2O → a ribonucleoside 5'-monophosphate + a single-stranded oligodeoxyribonucleotide ,
3.1.11.-: a double stranded DNA + H2O → a single stranded DNA + a 5'-phosphomononucleotide ,
3.1.11.-: DNAn + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.1: RNase II degradation substrate mRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.3: an oligonucleotide + H2O → n a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.-: RNase R degradation substrate RNA + n-1 H2O → n-2 a nucleoside 5'-monophosphate + a diribonucleotide ,
3.1.13.-: RNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.21.1: a double stranded DNA[periplasmic space] + 2n H2O[periplasmic space] → n a 5'-phosphooligonucleotide[periplasmic space] + n a 5' phosphodinucleotide[periplasmic space] ,
3.1.21.2: a single stranded DNA + n H2O → n a 5'-phosphooligonucleotide ,
3.1.21.3: ATP + DNAn + H2O → a double stranded DNA with 5'-terminal phosphate + ADP + phosphate ,
3.1.21.7: DNAn + H2O → a 3'-hydroxy terminated DNA + a 5'-phospho terminated DNA ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.11: a tRNA precursor + H2O → mature tRNA + a single-stranded oligoribonucleotide ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.27.6: an mRNA[periplasmic space] + H2O[periplasmic space] → 2 a single-stranded RNA[periplasmic space] ,
3.1.27.-: RNA + H2O → 2',3' -cyclic nucleotide phosphate + a 3' phosphooligonucleotide ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → n a 1,4-α-D-glucan ,
3.2.1.1: a 1,4-α-D-glucan[periplasmic space] + n H2O[periplasmic space] → a 1,4-α-D-glucan[periplasmic space] + maltohexaose[periplasmic space] ,
3.2.1.14: EC 3.2.1.14 ,
3.2.1.17: a peptidoglycan + H2O → a N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol + N-acetyl-D-glucosamine ,
3.2.1.20: (1,4-α-D-glucosyl)(n) + H2O → (1,4-α-D-glucosyl)(n-1) + α-D-glucose ,
3.2.1.20: maltopentaose + H2O → maltotetraose + α-D-glucose ,
3.2.1.20: maltohexaose + H2O → maltopentaose + α-D-glucose ,
3.2.1.20: maltoheptaose + H2O → maltohexaose + α-D-glucose ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.21: a β-D glucoside[periplasmic space] + H2O[periplasmic space] → a non glucosylated glucose acceptor[periplasmic space] + β-D-glucose[periplasmic space] ,
3.2.1.22: melibiose + H2O → α-D-galactose + β-D-glucose ,
3.2.1.23: α-lactose + H2O → β-D-galactose + β-D-glucose ,
3.2.1.28: α,α-trehalose + H2O → β-D-glucose + α-D-glucose ,
3.2.1.31: a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol ,
3.2.1.33: a limit dextrin + H2O → a debranched limit dextrin + maltotetraose ,
3.2.1.42: GDP-α-D-glucose + H2O → β-D-glucose + GDP + H+ ,
3.2.1.52: an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.1.86: β-D-cellobiose 6'-phosphate + H2O → β-D-glucose 6-phosphate + β-D-glucose ,
3.2.1.86: arbutin-6-phosphate + H2O → β-D-glucose 6-phosphate + benzene-1,4-diol ,
3.2.1.86: salicin 6-phosphate + H2O → β-D-glucose 6-phosphate + salicyl alcohol ,
3.2.1.86: methyl β-D-glucoside 6-phosphate + H2O → β-D-glucose 6-phosphate + methanol ,
3.2.1.86: N-monoacetylchitobiose 6'-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + D-glucosamine ,
3.2.1.93: α,α-trehalose 6-phosphate + H2O → β-D-glucose 6-phosphate + D-glucopyranose ,
3.2.1.170: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O → α-D-mannose 6-phosphate + D-glycerate ,
3.2.1.177: isoprimeverose + H2O → β-D-glucose + α-D-xylopyranose ,
3.2.1.177: xylan + n H2O → n α-D-xylopyranose ,
3.2.1.-: nigerose + H2O → 2 α-D-glucose ,
3.2.1.-: GDP-α-D-mannose + H2O → D-mannose + GDP + H+ ,
3.2.2.1: xanthosine + H2O → D-ribofuranose + xanthine ,
3.2.2.2: inosine + H2O → D-ribofuranose + hypoxanthine ,
3.2.2.3: cytidine + H2O → D-ribofuranose + cytosine ,
3.2.2.3: uridine + H2O → D-ribofuranose + uracil ,
3.2.2.4: AMP + H2O → D-ribofuranose 5-phosphate + adenine ,
3.2.2.5: NAD+ + H2O ↔ ADP-D-ribose + nicotinamide + H+ ,
3.2.2.7: adenosine + H2O → D-ribofuranose + adenine ,
3.2.2.8: a pyrimidine nucleoside + H2O + H+ → a pyrimidine base + D-ribofuranose ,
3.2.2.9: S-adenosyl-L-homocysteine + H2O ← S-ribosyl-L-homocysteine + adenine ,
3.2.2.14: β-nicotinamide D-ribonucleotide + H2O ↔ D-ribofuranose 5-phosphate + nicotinamide + H+ ,
3.2.2.16: S-methyl-5'-thioadenosine + H2O → S-methyl-5-thio-D-ribose + adenine ,
3.2.2.21: an alkylated DNA + H2O → DNAn + an alkylated nucleobase ,
3.2.2.23: a DNA containing ring-opened 7-methylguanine + H2O → 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + a DNA containing an apurinic site ,
3.2.2.28: DNA containing a base with lesion + H2O → a DNA containing an apurinic/apyrimidinic site + base with lesion ,
3.3.2.1: isochorismate + H2O → pyruvate + (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate ,
3.3.2.12: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O → 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde ,
3.4.11.2: a polypeptide + H2O → a polypeptide + an L-amino acid ,
3.4.11.4: a tripeptide + H2O → a dipeptide + a standard α amino acid ,
3.4.11.9: a peptide + H2O → a standard α amino acid + a peptide ,
3.4.11.18: a peptide with N-terminal L-methionine + H2O → L-methionine + a peptide ,
3.4.11.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.11.-: a protein[periplasmic space] + H2O[periplasmic space] → a peptide[periplasmic space] + L-arginine[periplasmic space] ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.13.18: a dipeptide + H2O → 2 a standard α amino acid ,
3.4.13.18: L-cysteinyl-glycine + H2O → L-cysteine + glycine ,
3.4.13.18: glycyl-L-methionine + H2O → glycine + L-methionine ,
3.4.13.18: L-alanyl-L-aspartate + H2O → L-alanine + L-aspartate ,
3.4.13.18: L-alanyl-L-glutamine + H2O → L-alanine + L-glutamine ,
3.4.13.18: L-alanyl-glycine + H2O → L-alanine + glycine ,
3.4.13.18: L-alanyl-L-histidine + H2O → L-alanine + L-histidine ,
3.4.13.18: L-alanyl-L-leucine + H2O → L-alanine + L-leucine ,
3.4.13.18: L-alanyl-L-threonine + H2O → L-alanine + L-threonine ,
3.4.13.18: L-alanyl-L-glutamate + H2O → L-alanine + L-glutamate ,
3.4.13.18: glycyl-L-asparagine + H2O → glycine + L-asparagine ,
3.4.13.18: glycyl-L-glutamine + H2O → glycine + L-glutamine ,
3.4.13.18: glycyl-L-glutamate + H2O → glycine + L-glutamate ,
3.4.13.18: L-methionyl-L-alanine dipeptide + H2O → L-methionine + L-alanine ,
3.4.13.18: glycyl-L-aspartate + H2O → glycine + L-aspartate ,
3.4.13.18: glycyl-L-proline + H2O → glycine + L-proline ,
3.4.13.21: a dipetide with L-aspartate at the N-terminal + H2O → L-aspartate + a standard α amino acid ,
3.4.13.22: D-alanyl-D-alanine + H2O → 2 D-alanine ,
3.4.15.5: an oligopeptide[periplasmic space] + H2O[periplasmic space] → a peptide[periplasmic space] + a dipeptide[periplasmic space] ,
3.4.16.4: a lipid II[periplasmic space] + H2O[periplasmic space] → a N-acetylglucosamine--N-acetylmuramyl-(tetrapeptide) pyrophosphoryl-undecaprenol[periplasmic space] + D-alanine[periplasmic space] ,
3.4.16.4: 2 a peptidoglycan dimer (meso-diaminopimelate containing)[periplasmic space] → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)[periplasmic space] + D-alanine[periplasmic space] ,
3.4.17.13: L-Ala-γ-D-Glu-meso-DAP-D-Ala + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine ,
3.4.19.12: a ubiquitin C-terminal thioester + H2O → a ubiquitin + a thiol ,
3.4.19.13: glutathione[periplasmic space] + H2O[periplasmic space] → L-cysteinyl-glycine[periplasmic space] + L-glutamate[periplasmic space] ,
3.4.19.-: β-aspartyl dipeptide + H2O → L-aspartate + a standard α amino acid ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.83: an oligopeptide + H2O → a peptide + a peptide ,
3.4.21.89: a peptide with a leader sequence + H2O → a peptide + a leader sequence ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.102: a protein[periplasmic space] + H2O[periplasmic space] → a peptide[periplasmic space] + a peptide[periplasmic space] ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a cleaved lipoprotein signal peptide + H2O → n a peptide ,
3.4.21.-: a polypeptide[periplasmic space] + H2O[periplasmic space] → 2 a polypeptide[periplasmic space] ,
3.4.23.36: a prolipoprotein + H2O → a lipoprotein + a cleaved lipoprotein signal peptide ,
3.4.23.43: a type IV prepillin + H2O → a cleaved type IV prepillin + a peptide ,
3.4.23.49: a protein + H2O → a peptide + a peptide ,
3.4.23.51: a precursor of large subunit of hydrogenase 3 + H2O → a C terminal 32 amino-acid peptide + a large subunit of hydrogenase 3 ,
3.4.24.55: a protein + H2O → n a peptide ,
3.4.24.70: an oligopeptide + H2O → a peptide + a peptide ,
3.4.24.-: a protein + H2O → a peptide + a peptide ,
3.4.-.-: peptidoglycan DAP-DAP crosslink[periplasmic space] + H2O[periplasmic space] → peptidoglycan tripeptide, glycan chain 1[periplasmic space] + peptidoglycan tetrapeptide, glycan chain 2[periplasmic space] ,
3.4.-.-: peptidoglycan D-alanyl-DAP crosslink[periplasmic space] + H2O[periplasmic space] → peptidoglycan tetrapeptide, glycan chain 2[periplasmic space] + peptidoglycan tetrapeptide, glycan chain 1[periplasmic space] ,
3.5.1.10: an N10-formyl-tetrahydrofolate + H2O → a tetrahydrofolate + formate + H+ ,
3.5.1.16: N-acetyl-L-ornithine + H2O → L-ornithine + acetate ,
3.5.1.18: N-succinyl-L,L-2,6-diaminopimelate + H2O ↔ L,L-diaminopimelate + succinate ,
3.5.1.19: nicotinamide + H2O → ammonium + nicotinate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala ,
3.5.1.38: L-asparagine + H2O → L-aspartate + ammonium ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.42: β-nicotinamide D-ribonucleotide + H2O → ammonium + β-nicotinate D-ribonucleotide ,
3.5.1.78: glutathionylspermidine + H2O → glutathione + spermidine ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O → a [protein] N-terminal L-methionine + formate ,
3.5.1.94: 4-(γ-L-glutamylamino)butanoate + H2O → 4-aminobutanoate + L-glutamate ,
3.5.1.96: N2-succinylglutamate + H2O → succinate + L-glutamate ,
3.5.1.105: N,N'-diacetylchitobiose + H2O = N-monoacetylchitobiose + acetate ,
3.5.1.105: N,N'-diacetylchitobiose 6'-phosphate + H2O → N-monoacetylchitobiose 6'-phosphate + acetate ,
3.5.1.108: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + H2O → UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine + acetate ,
3.5.1.-: p-aminobenzoyl glutamate + H2O → 4-aminobenzoate + L-glutamate ,
3.5.1.-: pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
3.5.2.3: (S)-dihydroorotate + H2O ↔ N-carbamoyl-L-aspartate + H+ ,
3.5.2.5: (S)-(+)-allantoin + H2O → allantoate + H+ ,
3.5.2.6: a β-lactam[periplasmic space] + H2O[periplasmic space] → a substituted β-amino acid[periplasmic space] ,
3.5.2.-: phenylhydantoin + H2O = phenylureidoacetic acid ,
3.5.3.9: allantoate + 2 H+ + H2O → S-ureidoglycine + ammonium + CO2 ,
3.5.3.11: agmatine + H2O → urea + putrescine ,
3.5.3.23: N2-succinyl-L-arginine + 2 H+ + 2 H2O → 2 ammonium + N2-succinyl-L-ornithine + CO2 ,
3.5.3.26: S-ureidoglycine + H2O → S-ureidoglycolate + ammonium ,
3.5.4.1: cytosine + H+ + H2O → ammonium + uracil ,
3.5.4.2: adenine + H+ + H2O → ammonium + hypoxanthine ,
3.5.4.3: guanine + H+ + H2O → ammonium + xanthine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.5: 2'-deoxycytidine + H+ + H2O → 2'-deoxyuridine + ammonium ,
3.5.4.5: cytidine + H+ + H2O → uridine + ammonium ,
3.5.4.9: a 5,10-methenyltetrahydrofolate + H2O ↔ an N10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ↔ 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.13: dCTP + H+ + H2O → ammonium + dUTP ,
3.5.4.16: GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+ ,
3.5.4.19: 1-(5-phospho-β-D-ribosyl)-AMP + H2O → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ,
3.5.4.25: GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+ ,
3.5.4.26: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ + H2O → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium ,
3.5.99.6: α-D-glucosamine 6-phosphate + H2O ↔ ammonium + β-D-fructofuranose 6-phosphate ,
3.5.99.10: 2-iminopropanoate + H+ + H2O → pyruvate + ammonium ,
3.5.99.-: (S)-2,3,4,5-tetrahydrodipicolinate + H+ + H2O ↔ L-α-amino-ε-keto-pimelate ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.6: a nucleoside diphosphate + H2O → a nucleoside 5'-monophosphate + phosphate + H+ ,
3.6.1.6: UDP + H2O → UMP + phosphate + H+ ,
3.6.1.6: CDP + H2O → CMP + phosphate + H+ ,
3.6.1.7: an acyl phosphate + H2O → a carboxylate + phosphate + H+ ,
3.6.1.8: ATP + H2O → AMP + diphosphate + H+ ,
3.6.1.9: NADH + H2O → NMNH + AMP + 2 H+ ,
3.6.1.11: (polyphosphate)(n) + H2O → (polyphosphate)(n-1) + phosphate ,
3.6.1.15: ATP + H2O → ADP + phosphate + H+ ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.19: a nucleoside triphosphate + H2O → a nucleoside 5'-monophosphate + diphosphate + H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.19: UTP + H2O → UMP + diphosphate + H+ ,
3.6.1.19: dATP + H2O → dAMP + diphosphate + H+ ,
3.6.1.19: dGTP + H2O → dGMP + diphosphate + H+ ,
3.6.1.19: dTTP + H2O → dTMP + diphosphate + H+ ,
3.6.1.19: ITP + H2O → IMP + diphosphate + H+ ,
3.6.1.21: an ADP-sugar + H2O → AMP + an α-D-aldose 1-phosphate ,
3.6.1.22: NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ ,
3.6.1.25: PPPi + H2O → phosphate + diphosphate ,
3.6.1.26: a CDP-diacylglycerol + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + CMP + 2 H+ ,
3.6.1.27: di-trans,octa-cis-undecaprenyl diphosphate + H2O → di-trans,octa-cis-undecaprenyl phosphate + phosphate + H+ ,
3.6.1.31: 1-(5-phospho-β-D-ribosyl)-ATP + H2O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H+ ,
3.6.1.40: pppGpp + H2O → ppGpp + phosphate + H+ ,
3.6.1.41: 5',5'''-diadenosine tetraphosphate + H2O → 2 ADP + 2 H+ ,
3.6.1.42: GDP + H2O → GMP + phosphate + H+ ,
3.6.1.45: a UDP-sugar[periplasmic space] + H2O[periplasmic space] → UMP[periplasmic space] + an α-D-aldose 1-phosphate[periplasmic space] + 2 H+[periplasmic space] ,
3.6.1.53: ADP-D-ribose + H2O → AMP + D-ribofuranose 5-phosphate + 2 H+ ,
3.6.1.54: UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.56: 2-hydroxy-dATP + H2O → 2-hydroxy-dAMP + diphosphate + H+ ,
3.6.1.58: 8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+ ,
3.6.1.63: α-D-ribose-1-methylphosphonate-5-triphosphate + H2O → α-D-ribose-1-methylphosphonate 5-phosphate + diphosphate + H+ ,
3.6.1.65: dCTP + H2O → dCMP + diphosphate + H+ ,
3.6.1.65: CTP + H2O → CMP + diphosphate + H+ ,
3.6.1.66: dITP + H2O → dIMP + diphosphate + H+ ,
3.6.1.66: XTP + H2O → XMP + diphosphate + H+ ,
3.6.1.-: XTP + H2O → XDP + phosphate + H+ ,
3.6.1.-: ITP + H2O → IDP + phosphate + H+ ,
3.6.1.-: thiamin diphosphate + H2O ↔ thiamin phosphate + phosphate + H+ ,
3.6.1.-: 5-hydroxy-CTP + H2O → 5-hydroxy-CMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GDP + H2O → 8-oxo-GMP + phosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.1.-: 7,8-dihydroneopterin 3'-triphosphate + H2O → 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ ,
3.6.1.-: 7,8-dihydroneopterin 3'-phosphate + H2O → 7,8-dihydroneopterin + phosphate ,
3.6.3.2: Mg2+[periplasmic space] + ATP + H2O → Mg2+[cytosol] + ADP + phosphate + H+ ,
3.6.3.5: Zn2+[cytosol] + ATP + H2O → Zn2+[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.12: K+[periplasmic space] + ATP + H2O → K+[cytosol] + ADP + phosphate + H+ ,
3.6.3.14: ATP + 4 H+[cytosol] + H2O ↔ ADP + phosphate + 5 H+[periplasmic space] ,
3.6.3.17: ATP + β-D-galactose[periplasmic space] + H2O → ADP + β-D-galactose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + β-D-ribopyranose[periplasmic space] + H2O → ADP + β-D-ribopyranose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + D-xylose[periplasmic space] + H2O → ADP + D-xylose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + L-arabinose[periplasmic space] + H2O → ADP + L-arabinose[cytosol] + phosphate + H+ ,
3.6.3.19: maltose[periplasmic space] + ATP + H2O → maltose[cytosol] + ADP + phosphate + H+ ,
3.6.3.20: ATP + sn-glycerol 3-phosphate[periplasmic space] + H2O → ADP + sn-glycerol 3-phosphate[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-glutamine[periplasmic space] + H2O → ADP + L-glutamine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-arginine[periplasmic space] + H2O → ADP + L-arginine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-aspartate[periplasmic space] + H2O → L-aspartate[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: L-lysine[periplasmic space] + ATP + H2O → L-lysine[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: ATP + L-histidine[periplasmic space] + H2O → ADP + L-histidine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-ornithine[periplasmic space] + H2O → ADP + L-ornithine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-glutamate[periplasmic space] + H2O → ADP + L-glutamate[cytosol] + phosphate + H+ ,
3.6.3.24: Ni2+[periplasmic space] + ATP + H2O → Ni2+[cytosol] + ADP + phosphate + H+ ,
3.6.3.25: ATP + thiosulfate[periplasmic space] + H2O → ADP + thiosulfate[cytosol] + phosphate + H+ ,
3.6.3.25: sulfate[periplasmic space] + ATP + H2O → sulfate[cytosol] + ADP + phosphate + H+ ,
3.6.3.27: ATP + phosphate[periplasmic space] + H2O → ADP + 2 phosphate[cytosol] + H+ ,
3.6.3.28: ATP + an alkylphosphonate[periplasmic space] + H2O → ADP + an alkylphosphonate[cytosol] + phosphate + H+ ,
3.6.3.29: ATP + molybdate[periplasmic space] + H2O → ADP + molybdate[cytosol] + phosphate + H+ ,
3.6.3.31: ATP + putrescine[periplasmic space] + H2O → ADP + putrescine[cytosol] + phosphate + H+ ,
3.6.3.31: ATP + spermidine[periplasmic space] + H2O → ADP + spermidine[cytosol] + phosphate + H+ ,
3.6.3.32: a quaternary amine[periplasmic space] + ATP + H2O → a quaternary amine[cytosol] + ADP + phosphate + H+ ,
3.6.3.33: ATP + cob(I)alamin[periplasmic space] + H2O → ADP + cob(I)alamin[cytosol] + phosphate + H+ ,
3.6.3.34: ATP + a ferric hydroxamate complex[periplasmic space] + H2O → ADP + a ferric hydroxamate complex[cytosol] + phosphate ,
3.6.3.34: ATP + ferric dicitrate[periplasmic space] + H2O → ADP + ferric dicitrate[cytosol] + phosphate + H+ ,
3.6.3.34: ATP + ferric enterobactin complex[periplasmic space] + H2O → ADP + ferric enterobactin complex[cytosol] + phosphate + H+ ,
3.6.3.36: taurine[periplasmic space] + ATP + H2O → taurine[cytosol] + ADP + phosphate + H+ ,
3.6.3.39: a lipopolysaccharide[cytosol] + ATP + H2O → a lipopolysaccharide[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.41: heme b[cytosol] + ATP + H2O → heme b[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.-: maltotetraose[periplasmic space] + ATP + H2O → ADP + maltotetraose[cytosol] + phosphate + H+ ,
3.6.3.-: α-D-galactofuranose[periplasmic space] + ATP + H2O → α-D-galactofuranose[cytosol] + ADP + phosphate + H+ ,
3.6.3.-: maltotriose[periplasmic space] + ATP + H2O → ADP + maltotriose[cytosol] + phosphate + H+ ,
3.6.3.-: L-idonate[periplasmic space] + H+[periplasmic space] → L-idonate[cytosol] + H+[cytosol] ,
3.6.4.10: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.13: ATP + H2O → ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
3.7.1.14: (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O → (2Z)-2-hydroxypenta-2,4-dienoate + succinate + H+ ,
3.7.1.14: (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H2O → (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H+ ,
3.9.1.-: GMP-N-ε-(N-α-acetyl lysine methyl ester) 5'-phosphoramidate + H2O → GMP + N-α-acetyl lysine methyl ester ,
3.13.1.-: 3-sulfinoalanine + H2O = L-alanine + sulfite + H+ ,
4.1.1.8: oxalyl-CoA + H+ = CO2 + formyl-CoA ,
4.1.1.11: L-aspartate + H+ → β-alanine + CO2 ,
4.1.1.15: L-glutamate + H+ → CO2 + 4-aminobutanoate ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.18: L-lysine + H+ → CO2 + cadaverine ,
4.1.1.19: L-arginine + H+ → CO2 + agmatine ,
4.1.1.20: meso-diaminopimelate + H+ → L-lysine + CO2 ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.31: oxaloacetate + phosphate ↔ phosphoenolpyruvate + hydrogen carbonate ,
4.1.1.36: R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → 4 CO2 + coproporphyrinogen III ,
4.1.1.41: (R)-methylmalonyl-CoA + H+ → propanoyl-CoA + CO2 ,
4.1.1.47: 2 glyoxylate + H+ → CO2 + tartronate semialdehyde ,
4.1.1.48: 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O ,
4.1.1.49: oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.65: an L-1-phosphatidylserine + H+ → an L-1-phosphatidyl-ethanolamine + CO2 ,
4.1.1.85: 3-keto-L-gulonate 6-phosphate + H+ → L-xylulose -5-phosphate + CO2 ,
4.1.1.98: 3-octaprenyl-4-hydroxybenzoate + H+ → 2-octaprenylphenol + CO2 ,
4.1.1.-: a 3-oxoacid + H+ → a methylketone + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate ↔ acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.8: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate ↔ indole + D-glyceraldehyde 3-phosphate ,
4.1.2.13: fructose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.17: L-fuculose 1-phosphate ↔ (S)-lactaldehyde + dihydroxyacetone phosphate ,
4.1.2.19: L-rhamnulose 1-phosphate ↔ (S)-lactaldehyde + dihydroxyacetone phosphate ,
4.1.2.20: 5-dehydro-4-deoxy-D-glucarate ↔ pyruvate + tartronate semialdehyde ,
4.1.2.25: 7,8-dihydroneopterin → glycolaldehyde + 6-hydroxymethyl-7,8-dihydropterin ,
4.1.2.26: L-threo-3-phenylserine = benzaldehyde + glycine ,
4.1.2.28: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate ,
4.1.2.40: D-tagatofuranose 1,6-bisphosphate ↔ dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.48/4.1.2.49: L-allo-threonine ↔ glycine + acetaldehyde ,
4.1.2.48: L-threonine → acetaldehyde + glycine ,
4.1.2.50: 7,8-dihydroneopterin 3'-triphosphate + H2O → 6-carboxy-5,6,7,8-tetrahydropterin + PPPi + acetaldehyde + 2 H+ ,
4.1.2.51: 2-dehydro-3-deoxy-D-gluconate = D-glyceraldehyde + pyruvate ,
4.1.2.53: 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde ,
4.1.2.55: 2-dehydro-3-deoxy-D-galactonate 6-phosphate ↔ D-glyceraldehyde 3-phosphate + pyruvate ,
4.1.2.55: 2-dehydro-3-deoxy-D-gluconate 6-phosphate → D-glyceraldehyde 3-phosphate + pyruvate ,
4.1.2.57: 6-deoxy-6-sulfo-D-fructose 1-phosphate → sulfolactaldehyde + dihydroxyacetone phosphate ,
4.1.2.-: dihydroxyacetone phosphate + D-erythrose 4-phosphate ← D-sedoheptulose-1,7-bisphosphate ,
4.1.2.-: 4-hydroxy-L-threonine ↔ glycolaldehyde + glycine ,
4.1.2.-: DL-allothreonine ↔ acetaldehyde + glycine ,
4.1.2.-: β-D-fructofuranose 6-phosphate ↔ dihydroxyacetone + D-glyceraldehyde 3-phosphate ,
4.1.3.1: D-threo-isocitrate ↔ glyoxylate + succinate ,
4.1.3.3: N-acetylneuraminate ↔ N-acetyl-D-mannosamine + pyruvate ,
4.1.3.3: N-acetyl-β-neuraminate = N-acetyl-β-D-mannosamine + pyruvate ,
4.1.3.6: citrate → acetate + oxaloacetate ,
4.1.3.27: chorismate + L-glutamine → anthranilate + pyruvate + L-glutamate + H+ ,
4.1.3.30: (2R,3S)-2-methylisocitrate ↔ succinate + pyruvate ,
4.1.3.36: 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + H+ → 1,4-dihydroxy-2-naphthoyl-CoA + H2O ,
4.1.3.38: 4-amino-4-deoxychorismate ↔ 4-aminobenzoate + pyruvate + H+ ,
4.1.3.39: 4-hydroxy-2-oxopentanoate ↔ acetaldehyde + pyruvate ,
4.1.3.40: chorismate → 4-hydroxybenzoate + pyruvate ,
4.1.3.42: (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate ,
4.1.99.1: L-tryptophan + H2O = ammonium + indole + pyruvate ,
4.1.99.12: D-ribulose 5-phosphate → 1-deoxy-L-glycero-tetrulose 4-phosphate + formate + H+ ,
4.1.99.17: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + carbon monoxide + 3 H+ ,
4.1.99.18: GTP → cyclic pyranopterin phosphate + diphosphate ,
4.1.99.19: L-tyrosine + S-adenosyl-L-methionine + NADPH → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP+ + H+ ,
4.2.1.1: hydrogen carbonate + H+ ↔ CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.7: D-altronate → 2-dehydro-3-deoxy-D-gluconate + H2O ,
4.2.1.8: D-mannonate → 2-dehydro-3-deoxy-D-gluconate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylbutanoate → 3-methyl-2-oxobutanoate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylpentanoate → (S)-3-methyl-2-oxopentanoate + H2O ,
4.2.1.10: 3-dehydroquinate ↔ 3-dehydroshikimate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.12: D-gluconate 6-phosphate → 2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O ,
4.2.1.17: a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O ,
4.2.1.17: 3-hydroxyadipyl-CoA ↔ 2,3-didehydroadipyl-CoA + H2O ,
4.2.1.19: D-erythro-imidazole-glycerol-phosphate → imidazole acetol-phosphate + H2O ,
4.2.1.20: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine → L-tryptophan + D-glyceraldehyde 3-phosphate + H2O ,
4.2.1.24: 2 5-aminolevulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.32: L-tartrate ↔ oxaloacetate + H2O ,
4.2.1.40: D-glucarate → 5-dehydro-4-deoxy-D-glucarate + H2O ,
4.2.1.42: D-galactarate → 5-dehydro-4-deoxy-D-glucarate + H2O ,
4.2.1.46: dTDP-α-D-glucose → dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O ,
4.2.1.47: GDP-α-D-mannose → GDP-4-dehydro-α-D-rhamnose + H2O ,
4.2.1.51: prephenate + H+ → 2-oxo-3-phenylpropanoate + CO2 + H2O ,
4.2.1.55: (R)-3-hydroxybutanoyl-CoA = crotonyl-CoA + H2O ,
4.2.1.70: D-ribofuranose 5-phosphate + uracil ↔ pseudouridine 5'-phosphate + H2O ,
4.2.1.75: hydroxymethylbilane → uroporphyrinogen-III + H2O ,
4.2.1.79: (2S,3S)-2-methylcitrate → cis-2-methylaconitate + H2O ,
4.2.1.80: 2-oxopent-4-enoate + H2O → 4-hydroxy-2-oxopentanoate ,
4.2.1.81: D-tartrate = oxaloacetate + H2O ,
4.2.1.82: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O ,
4.2.1.90: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O ,
4.2.1.99: (2R,3S)-2-methylisocitrate ↔ cis-2-methylaconitate + H2O ,
4.2.1.104: cyanate + hydrogen carbonate + H+ → carbamate + CO2 ,
4.2.1.113: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate → 2-succinylbenzoate + H2O ,
4.2.1.122: indole + L-serine → L-tryptophan + H2O ,
4.2.1.126: N-acetyl-β-muramate 6-phosphate + H2O ↔ N-acetyl-D-glucosamine 6-phosphate + (R)-lactate ,
4.2.1.130: (R)-lactate + H+ ← methylglyoxal + H2O ,
4.2.1.136: (S)-NADPHX + ADP → AMP + NADPH + phosphate + H+ ,
4.2.1.136: ADP + (S)-NADHX → AMP + NADH + phosphate + H+ ,
4.2.1.140: D-galactonate → 2-dehydro-3-deoxy-D-galactonate + H2O ,
4.2.1.149: L-carnitinyl-CoA → crotonobetainyl-CoA + H2O ,
4.2.2.-: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide ,
4.2.3.1: O-phospho-L-homoserine + H2O → L-threonine + phosphate ,
4.2.3.3: dihydroxyacetone phosphate → methylglyoxal + phosphate ,
4.2.3.4: 3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate ,
4.2.3.5: 5-enolpyruvyl-shikimate 3-phosphate → chorismate + phosphate ,
4.2.99.20: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate → (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate ,
4.3.1.1: L-aspartate ↔ ammonium + fumarate ,
4.3.1.7: ethanolamine → ammonium + acetaldehyde ,
4.3.1.15: 2,3-diaminopropanoate + H+ + H2O → 2 ammonium + pyruvate ,
4.3.1.17: L-serine → pyruvate + ammonium ,
4.3.1.18: D-serine = pyruvate + ammonium ,
4.3.1.19: L-threonine → 2-oxobutanoate + ammonium ,
4.3.1.-: O-succinyl-L-homoserine + H2O → 2-oxobutanoate + succinate + ammonium + H+ ,
4.3.2.1: L-arginino-succinate ↔ L-arginine + fumarate ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.3: S-ureidoglycolate → urea + glyoxylate ,
4.3.3.7: pyruvate + L-aspartate-semialdehyde → (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ ,
4.3.99.3: 6-carboxy-5,6,7,8-tetrahydropterin + H+ → 7-carboxy-7-deazaguanine + ammonium ,
4.4.1.1/4.4.1.-: L-cysteine + H2O → pyruvate + ammonium + hydrogen sulfide ,
4.4.1.5: (R)-S-lactoylglutathione ← methylglyoxal + glutathione ,
4.4.1.8: L-cystathionine + H2O → ammonium + pyruvate + L-homocysteine ,
4.4.1.15: D-cysteine + H2O → ammonium + pyruvate + hydrogen sulfide ,
4.4.1.16: L-selenocysteine + a reduced electron acceptor = L-alanine + selenide + an oxidized electron acceptor + 2 H+ ,
4.4.1.21: S-ribosyl-L-homocysteine → L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.5.1.2: 3-chloro-D-alanine + thioglycolate = S-carboxymethyl-D-cysteine + chloride + H+ ,
4.6.1.1: ATP → cyclic-AMP + diphosphate ,
4.6.1.2: GTP ↔ cyclic-GMP + diphosphate ,
4.6.1.12: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol → CMP + 2-C-methyl-D-erythritol-2,4-cyclodiphosphate ,
4.7.1.1: α-D-ribose-1-methylphosphonate 5-phosphate → 5-phospho-α-D-ribose 1,2-cyclic phosphate + methane ,
4.99.1.1: Fe2+ + protoporphyrin IX → protoheme IX + 2 H+ ,
4.99.1.4: sirohydrochlorin + Fe2+ ↔ siroheme + 2 H+ ,
5.1.1.1: L-alanine ↔ D-alanine ,
5.1.1.3: L-glutamate ↔ D-glutamate ,
5.1.1.7: L,L-diaminopimelate ↔ meso-diaminopimelate ,
5.1.1.-: L-alanyl-D-glutamate ↔ L-alanyl-L-glutamate ,
5.1.2.3: a (3R)-3-hydroxyacyl-CoA ↔ a (3S)-3-hydroxyacyl-CoA ,
5.1.2.-: L-idarate ↔ D-glucarate ,
5.1.3.1: D-ribulose 5-phosphate ↔ D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucose ,
5.1.3.3: β-D-galactose ↔ α-D-galactose ,
5.1.3.4: L-ribulose 5-phosphate ↔ D-xylulose 5-phosphate ,
5.1.3.9: N-acetyl-D-mannosamine 6-phosphate ↔ N-acetyl-D-glucosamine 6-phosphate ,
5.1.3.13: dTDP-4-dehydro-6-deoxy-α-D-glucopyranose → dTDP-4-dehydro-β-L-rhamnose ,
5.1.3.14: UDP-N-acetyl-α-D-glucosamine ↔ UDP-N-acetyl-α-D-mannosamine ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.20: ADP-D-glycero-β-D-manno-heptose → ADP-L-glycero-β-D-manno-heptose ,
5.1.3.22: L-ribulose 5-phosphate ← L-xylulose -5-phosphate ,
5.1.3.24: N-acetyl-α-neuraminate ↔ N-acetyl-β-neuraminate ,
5.1.3.29: α-L-fucopyranose ↔ β-L-fucopyranose ,
5.1.3.-: α-L-rhamnopyranose → β-L-rhamnopyranose ,
5.1.3.-: D-allulose 6-phosphate → β-D-fructofuranose 6-phosphate ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.1.3.-: β-L-lyxopyranose ↔ L-xylulose ,
5.1.99.1: (R)-methylmalonyl-CoA ↔ (S)-methylmalonyl-CoA ,
5.1.99.6: (R)-NADHX = (S)-NADHX ,
5.1.99.6: (R)-NADPHX = (S)-NADPHX ,
5.2.1.8: peptidylproline (ω = 180) = peptidylproline (ω = 0) ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ dihydroxyacetone phosphate ,
5.3.1.3: D-arabinopyranose ↔ D-ribulose ,
5.3.1.4: L-arabinopyranose ↔ L-ribulose ,
5.3.1.5: a D-xylopyranose ↔ D-xylulose ,
5.3.1.6: D-ribose 5-phosphate ↔ D-ribulose 5-phosphate ,
5.3.1.7: aldehydo-D-mannose ↔ keto-D-fructose ,
5.3.1.8: α-D-mannose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.12: aldehydo-D-galacturonate ↔ D-tagaturonate ,
5.3.1.12: aldehydo-D-glucuronate ↔ D-fructuronate ,
5.3.1.13: D-arabinose 5-phosphate ↔ D-ribulose 5-phosphate ,
5.3.1.14: β-L-rhamnopyranose ↔ keto-L-rhamnulose ,
5.3.1.16: 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide → phosphoribulosylformimino-AICAR-P ,
5.3.1.22: hydroxypyruvate ↔ tartronate semialdehyde ,
5.3.1.24: N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate ,
5.3.1.25: α-L-fucopyranose ↔ L-fuculose ,
5.3.1.28: D-sedoheptulose 7-phosphate → D-glycero-D-manno-heptose 7-phosphate ,
5.3.1.31: sulfoquinovose → 6-deoxy-6-sulfo-D-fructose ,
5.3.1.-: aldehydo-D-allose 6-phosphate ↔ D-allulose 6-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.2: oxaloacetate = enol-oxaloacetate ,
5.3.2.8: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate ↔ (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.7: trans-aconitate = cis-aconitate ,
5.3.3.8: a cis-3-enoyl-CoA ↔ a trans-2-enoyl-CoA ,
5.3.3.8: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA ,
5.3.3.14: a trans2-decenoyl-[acp] ↔ a cis3-decenoyl-[acp] ,
5.3.3.18: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA ↔ 2-oxepin-2(3H)-ylideneacetyl-CoA ,
5.3.3.-: 2-trans,5-cis-tetradecadienoyl-CoA ↔ 3-trans,5-cis-tetradecadienoyl-CoA ,
5.4.1.-: α-lactose = allolactose ,
5.4.2.5: α-D-glucose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.6: β-D-glucose 1-phosphate = β-D-glucose 6-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate ↔ 2-deoxy-D-ribose 5-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate ↔ D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ↔ α-D-mannose 6-phosphate ,
5.4.2.10: D-glucosamine 1-phosphate ↔ D-glucosamine 6-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.2.12: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.3.8: glutamate-1-semialdehyde → 5-aminolevulinate ,
5.4.3.-: L-lysine = D-β-lysine ,
5.4.4.2: chorismate ↔ isochorismate ,
5.4.99.2: (R)-methylmalonyl-CoA ↔ succinyl-CoA ,
5.4.99.5: chorismate → prephenate ,
5.4.99.9: UDP-α-D-galactose ↔ UDP-α-D-galactofuranose ,
5.4.99.18: N5-carboxyaminoimidazole ribonucleotide → 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ,
5.4.99.19: a uridine516 in 16S rRNA → a 16S rRNA pseudouridine516 ,
5.4.99.20: uridine2457 in 23S rRNA → a pseudouridine2457 in 23S rRNA ,
5.4.99.21: a uridine2604 in 23S rRNA → a pseudouridine2604 in 23S rRNA ,
5.4.99.22: uridine2605 in 23S rRNA → a pseudouridine2605 in 23S rRNA ,
5.4.99.23: a 23S rRNA uridine1911/1915/1917 → a pseudouridine1911/1915/1917 in 23S rRNA ,
5.4.99.24: uridine955/2504/2580 in 23S rRNA → a pseudouridine955/2504/2580 in 23S rRNA ,
5.4.99.25: a tRNA uridine55 = a tRNA pseudouridine55 ,
5.4.99.26: a tRNA uridine65 = a tRNA pseudouridine65 ,
5.4.99.27: a tRNA uridine13 = a pseudouridine13 in tRNA ,
5.4.99.28: a tRNA uridine32 → a pseudouridine32 in tRNA ,
5.4.99.29: uridine746 in 23S rRNA → a pseudouridine746 in 23S rRNA ,
5.4.99.-: β-D-ribopyranose ↔ β-D-ribofuranose ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
5.-.-.-: 7,8-dihydroneopterin 3'-triphosphate ↔ 7,8-dihydromonapterin triphosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.5: succinate + ATP + coenzyme A ↔ succinyl-CoA + ADP + phosphate ,
6.2.1.17: propanoate + ATP + coenzyme A → propanoyl-CoA + AMP + diphosphate ,
6.2.1.26: ATP + 2-succinylbenzoate + coenzyme A → AMP + 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + diphosphate ,
6.2.1.30: phenylacetate + ATP + coenzyme A → phenylacetyl-CoA + AMP + diphosphate ,
6.2.1.-: L-carnitine + ATP + coenzyme A → L-carnitinyl-CoA + AMP + diphosphate ,
6.3.1.1: L-aspartate + ammonium + ATP → L-asparagine + AMP + diphosphate + H+ ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.5: ammonium + ATP + nicotinate adenine dinucleotide → AMP + NAD+ + diphosphate + H+ ,
6.3.1.9: spermidine + glutathione + ATP → glutathionylspermidine + ADP + phosphate + H+ ,
6.3.1.11: putrescine + L-glutamate + ATP → γ-glutamyl-L-putrescine + ADP + phosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + AMP + diphosphate + H+ ,
6.3.2.2: L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+ ,
6.3.2.3: glycine + γ-L-glutamyl-L-cysteine + ATP → glutathione + ADP + phosphate + H+ ,
6.3.2.4: 2 D-alanine + ATP → D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.5: (R)-4'-phosphopantothenate + L-cysteine + CTP → CMP + R-4'-phosphopantothenoyl-L-cysteine + diphosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.8: L-alanine + UDP-N-α-D-acetylmuramate + ATP → UDP-N-acetylmuramoyl-L-alanine + ADP + phosphate + H+ ,
6.3.2.9: D-glutamate + UDP-N-acetylmuramoyl-L-alanine + ATP → UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + ADP + phosphate + H+ ,
6.3.2.10: D-alanyl-D-alanine + UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.12: L-glutamate + 7,8-dihydropteroate + ATP → ADP + 7,8-dihydrofolate monoglutamate + phosphate + H+ ,
6.3.2.13: meso-diaminopimelate + UDP-N-acetylmuramoyl-L-alanyl--D-glutamate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.14: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate → 6 AMP + enterobactin + 6 diphosphate + 3 H+ ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.-: UDP-N-α-D-acetylmuramate + L-Ala-γ-D-Glu-meso-DAP-D-Ala + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.-: a [protein chain elongation factor EF-P]-L-lysine34 + D-β-lysine + ATP → [a protein chain elongation factor EF-P]-β-L-lysyl-L-lysine34 + AMP + diphosphate + H+ ,
6.3.2.-: a [protein] C-terminal L-glutamate + L-glutamate + ATP → a [protein] with C-terminal α-L-glutamate-α-L-glutamate + ADP + phosphate + H+ ,
6.3.2.-: UDP-N-α-D-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: an N5-formyl-tetrahydrofolate + ATP → a 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.3.3: CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+ ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.13: ATP + 5-phospho-β-D-ribosylamine + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.18: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + hydrogen carbonate → N5-carboxyaminoimidazole ribonucleotide + ADP + phosphate + 2 H+ ,
6.3.4.20: 7-carboxy-7-deazaguanine + ammonium + ATP → preQ0 + ADP + phosphate + H+ + H2O ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → AMP + L-glutamate + NAD+ + diphosphate + H+ ,
6.3.5.2: L-glutamine + XMP + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + L-glutamate + phosphate + H+ ,
6.3.5.4: L-glutamine + L-aspartate + ATP + H2O → L-glutamate + L-asparagine + AMP + diphosphate + H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → carbamoyl-phosphate + L-glutamate + 2 ADP + phosphate + 2 H+ ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.3: ATP + hydrogen carbonate + propanoyl-CoA → ADP + (S)-methylmalonyl-CoA + phosphate + H+ ,
6.5.1.-: a 3' half-tRNA molecule with a hydroxyl on its 5' end + a 3' half-tRNA molecule with a hydroxyl on its 5' end + ATP → a ligated tRNA + AMP + diphosphate ,
6.5.1.-: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
6.-.-.-: a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + H+ → a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine + AMP + diphosphate ,
a D-glucoronoside[periplasmic space] + H+[periplasmic space] → a D-glucoronoside[cytosol] + H+[cytosol] ,
β-alanine[periplasmic space] + H+[periplasmic space] → β-alanine[cytosol] + H+[cytosol] ,
cadaverine[cytosol] + L-lysine[periplasmic space] → cadaverine[periplasmic space] + L-lysine[cytosol] ,
D-serine[periplasmic space] + H+[periplasmic space] → D-serine[cytosol] + H+[cytosol] ,
glycine betaine[periplasmic space] + H+[periplasmic space] → glycine betaine[cytosol] + H+[cytosol] ,
2-oxoglutarate[periplasmic space] + H+[periplasmic space] → 2-oxoglutarate[cytosol] + H+[cytosol] ,
β-D-fructofuranose[periplasmic space] + PtsI-Phis189 → β-D-fructofuranose 1-phosphate[cytosol] + PtsI ,
chloride[periplasmic space] → chloride[cytosol] ,
(S)-malate[periplasmic space] + 2 H+[periplasmic space] → (S)-malate[cytosol] + 2 H+[cytosol] ,
adenosine[periplasmic space] + H+[periplasmic space] → adenosine[cytosol] + H+[cytosol] ,
deoxycholate[cytosol] + H+[periplasmic space] → deoxycholate[periplasmic space] + H+[cytosol] ,
pyruvate[cytosol] → pyruvate[periplasmic space] ,
fumarate[periplasmic space] → fumarate[cytosol] ,
L-glyceraldehyde 3-phosphate[periplasmic space] + phosphate[cytosol] → L-glyceraldehyde 3-phosphate[cytosol] + phosphate[periplasmic space] ,
ferric coprogen[extracellular space] → ferric coprogen[periplasmic space] ,
a C4-dicarboxylate[periplasmic space] + 2 H+[periplasmic space] → a C4-dicarboxylate[cytosol] + 2 H+[cytosol] ,
4-methylphenol[cytosol] → 4-methylphenol[periplasmic space] ,
selenate[periplasmic space] + ATP + H2O → selenate[cytosol] + ADP + phosphate + H+ ,
methanol[cytosol] → methanol[periplasmic space] ,
a dipeptide[periplasmic space] + H+[periplasmic space] → a dipeptide[cytosol] + H+[cytosol] ,
L-valine[cytosol] → L-valine[periplasmic space] ,
N-acetyl-β-neuraminate[periplasmic space] + H+[periplasmic space]N-acetyl-β-neuraminate[cytosol] + H+[cytosol] ,
nitrate[out] + 2 H+[out] + 2 e- → nitrite[out] + H2O[out] ,
pyridoxamine[periplasmic space] → pyridoxamine[cytosol] ,
melibiose[periplasmic space] + H+[periplasmic space] → melibiose[cytosol] + H+[cytosol] ,
3-(3-hydroxyphenyl)propionate[periplasmic space] + H+[periplasmic space] → 3-(3-hydroxyphenyl)propionate[cytosol] + H+[cytosol] ,
L-asparagine[periplasmic space] + H+[periplasmic space] → L-asparagine[cytosol] + H+[cytosol] ,
a peptide antibiotic[periplasmic space] → a peptide antibiotic[cytosol] ,
an mRNA + H2O → an RNase product with a 3' phosphate + an RNase product with a 5' OH ,
glycerol[periplasmic space] ↔ glycerol[cytosol] ,
Na+[periplasmic space] + (R)-pantothenate[periplasmic space] → Na+[cytosol] + (R)-pantothenate[cytosol] ,
succinate[cytosol] + (S)-malate[periplasmic space] → (S)-malate[cytosol] + succinate[periplasmic space] ,
sulfate[periplasmic space] + x H+[periplasmic space] → sulfate[cytosol] + x H+[cytosol] ,
acetate[cytosol] ↔ acetate[periplasmic space] ,
ferrichrome[extracellular space] → ferrichrome[cytosol] ,
arsenate[periplasmic space] + H+[periplasmic space] → arsenate[cytosol] + H+[cytosol] ,
a lipopolysaccharide[periplasmic space] → a lipopolysaccharide[extracellular space] ,
ferric dicitrate[extracellular space] → ferric dicitrate[periplasmic space] ,
lanthionine[periplasmic space] → lanthionine[cytosol] ,
glutathione[periplasmic space] + ATP + H2O → glutathione[cytosol] + ADP + phosphate + H+ ,
Ca2+[periplasmic space] → Ca2+[cytosol] ,
L-methionine[cytosol] + H+[periplasmic space] → L-methionine[periplasmic space] + H+[cytosol] ,
oxygen[periplasmic space] ↔ oxygen[cytosol] ,
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[periplasmic space] + ATP + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[cytosol] + ADP + phosphate + H+ ,
cobinamide[extracellular space] → cobinamide[periplasmic space] ,
spermidine[cytosol] + H+[periplasmic space] → spermidine[periplasmic space] + H+[cytosol] ,
Zn2+[periplasmic space] + ATP + H2O → Zn2+[cytosol] + ADP + phosphate + H+ ,
D-gluconate[periplasmic space] + H+[periplasmic space] → D-gluconate[cytosol] + H+[cytosol] ,
pyridoxine[periplasmic space] → pyridoxine[cytosol] ,
non-specific ion/solute[cytosol] → non-specific ion/solute[periplasmic space] ,
L-phenylalanine[periplasmic space] + H+[periplasmic space] → L-phenylalanine[cytosol] + H+[cytosol] ,
L-tartrate[periplasmic space] + succinate[cytosol] → L-tartrate[cytosol] + succinate[periplasmic space] ,
2-dehydro-3-deoxy-D-gluconate[periplasmic space] + H+[periplasmic space] → 2-dehydro-3-deoxy-D-gluconate[cytosol] + H+[cytosol] ,
glycolate[periplasmic space] + H+[periplasmic space] → glycolate[cytosol] + H+[cytosol] ,
sulfoquinovose[periplasmic space] → sulfoquinovose[cytosol] ,
mono-, di-, or trisaccharide < 600 Da[extracellular space] → mono-, di-, or trisaccharide < 600 Da[periplasmic space] ,
cyclic-AMP[cytosol] ↔ cyclic-AMP[periplasmic space] ,
ferric enterobactin complex[extracellular space] → ferric enterobactin complex[cytosol] ,
ethanol[periplasmic space] ↔ ethanol[cytosol] ,
salicyl alcohol[cytosol] → salicyl alcohol[periplasmic space] ,
N-acetyl-DL-methionine[periplasmic space] + ATP + H2O → N-acetyl-DL-methionine[cytosol] + ADP + phosphate + H+ ,
Cd2+[periplasmic space] → Cd2+[cytosol] ,
a drug[cytosol] + 2 H+[periplasmic space] → a drug[periplasmic space] + 2 H+[cytosol] ,
thiamin diphosphate + phosphate + n H+[periplasmic space] → thiamin triphosphate + H2O + n H+[cytosol] ,
L-alanine[cytosol] → L-alanine[periplasmic space] ,
(R)-malate[periplasmic space] + 2 H+[periplasmic space] → (R)-malate[cytosol] + 2 H+[cytosol] ,
Cu+[cytosol] + H+[periplasmic space] → Cu+[extracellular space] + H+[cytosol] ,
N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[periplasmic space] + H+[periplasmic space]N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[cytosol] + H+[cytosol] ,
D-allose[periplasmic space] + ATP + H2O → D-allose[cytosol] + ADP + phosphate + H+ ,
ATP + D-methionine[periplasmic space] + H2O → ADP + D-methionine[cytosol] + phosphate + H+ ,
Fe2+[periplasmic space] → Fe2+[cytosol] ,
fosmidomycin[cytosol] + H+[periplasmic space] → fosmidomycin[periplasmic space] + H+[cytosol] ,
homoserine lactone[cytosol] + H+[periplasmic space] → homoserine lactone[periplasmic space] + H+[cytosol] ,
Ca2+[cytosol] → Ca2+[periplasmic space] ,
Na+[periplasmic space] + L-isoleucine[periplasmic space] → Na+[cytosol] + L-isoleucine[cytosol] ,
thymidine[periplasmic space] + H+[periplasmic space] → thymidine[cytosol] + H+[cytosol] ,
γ-butyrobetaine[cytosol] + L-carnitine[periplasmic space] → γ-butyrobetaine[periplasmic space] + L-carnitine[cytosol] ,
adenine[periplasmic space] → adenine[cytosol] ,
hydrophilic solute or ion < 600 Da[extracellular space] → hydrophilic solute or ion < 600 Da[periplasmic space] ,
xanthine[cytosol] → xanthine[periplasmic space] ,
methyl-β-D-galactoside[periplasmic space] + ATP + H2O → methyl-β-D-galactoside[cytosol] + ADP + phosphate + H+ ,
(3E,5Z)-tetradecadienoate[cytosol] → (3E,5Z)-tetradecadienoate[periplasmic space] ,
cob(I)alamin[extracellular space] → cob(I)alamin[periplasmic space] ,
L-cystine[periplasmic space] → L-cystine[cytosol] ,
glycine betaine[extracellular space] ↔ glycine betaine[periplasmic space] ,
trans-cinnamate[periplasmic space]trans-cinnamate[cytosol] ,
adenine[periplasmic space] + H+[periplasmic space] → adenine[cytosol] + H+[cytosol] ,
nitrate[periplasmic space] + nitrite[cytosol] → nitrate[cytosol] + nitrite[periplasmic space] ,
ATP + L-valine[periplasmic space] + H2O → ADP + L-valine[cytosol] + phosphate + H+ ,
Fe2+[cytosol] + H+[periplasmic space] → Fe2+[periplasmic space] + H+[cytosol] ,
ubiquinone-8 + 2 H+[in] + 2 e- → ubiquinol-8 ,
a polypeptide[cytosol] → a polypeptide[periplasmic space] ,
L-threonine[periplasmic space] + H+[periplasmic space] → L-threonine[cytosol] + H+[cytosol] ,
β-D-glucose 6-phosphate[periplasmic space] + phosphate[cytosol] → β-D-glucose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
α-lactose[periplasmic space] + H+[periplasmic space] → α-lactose[cytosol] + H+[cytosol] ,
L-glutamate[periplasmic space] + 2 H+[periplasmic space] → L-glutamate[cytosol] + 2 H+[cytosol] ,
Ni2+[periplasmic space] → Ni2+[cytosol] ,
L-aspartate[periplasmic space] + 2 H+[periplasmic space] → L-aspartate[cytosol] + 2 H+[cytosol] ,
2'-deoxyinosine[periplasmic space] + H+[periplasmic space] → 2'-deoxyinosine[cytosol] + H+[cytosol] ,
β-D-glucose[periplasmic space] → β-D-glucose[cytosol] ,
Fe2+[periplasmic space] + H+[periplasmic space] → Fe2+[cytosol] + H+[cytosol] ,
2-oxobutanoate[periplasmic space] → 2-oxobutanoate[cytosol] ,
pseudouridine[periplasmic space] → pseudouridine[cytosol] ,
a long-chain fatty acid[extracellular space] → a long-chain fatty acid[periplasmic space] ,
D-galactono-1,4-lactone[periplasmic space] → D-galactono-1,4-lactone[cytosol] ,
S-methyl-L-methionine[periplasmic space] → S-methyl-L-methionine[cytosol] ,
5,6-dimethylbenzimidazole[periplasmic space] → 5,6-dimethylbenzimidazole[cytosol] ,
(S)-(+)-allantoin[periplasmic space] → (S)-(+)-allantoin[cytosol] ,
4-hydroxybenzyl alcohol[cytosol] → 4-hydroxybenzyl alcohol[periplasmic space] ,
4-hydroxybenzoate[cytosol] + H+[periplasmic space] → 4-hydroxybenzoate[periplasmic space] + H+[cytosol] ,
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[periplasmic space] + H+[periplasmic space] → GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[cytosol] + H+[cytosol] ,
choline[periplasmic space] + H+[periplasmic space] → choline[cytosol] + H+[cytosol] ,
L-alanine[periplasmic space] + H+[periplasmic space] → L-alanine[cytosol] + H+[cytosol] ,
putrescine[periplasmic space] + H+[periplasmic space] → putrescine[cytosol] + H+[cytosol] ,
K+[periplasmic space] + H+[periplasmic space] → K+[cytosol] + H+[cytosol] ,
lipid A-core[cytosol] + ATP + H2O → lipid A-core[periplasmic space] + ADP + phosphate + H+ ,
β-D-fructofuranose[periplasmic space] + HPr-Phis15 → β-D-fructofuranose 6-phosphate[cytosol] + HPr ,
cyanate[periplasmic space] → cyanate[cytosol] ,
fumarate[periplasmic space] + 2 H+[periplasmic space] → fumarate[cytosol] + 2 H+[cytosol] ,
cytidine[periplasmic space] + H+[periplasmic space] → cytidine[cytosol] + H+[cytosol] ,
deoxycholate[periplasmic space] → deoxycholate[cytosol] ,
acetate[periplasmic space] + H+[periplasmic space] → acetate[cytosol] + H+[cytosol] ,
L-aspartate[periplasmic space] → L-aspartate[cytosol] ,
L-glyceraldehyde 3-phosphate[periplasmic space] → L-glyceraldehyde 3-phosphate[cytosol] ,
ferric (2,3-dihydroxybenzoylserine)3[extracellular space] → ferric (2,3-dihydroxybenzoylserine)3[periplasmic space] ,
methyl β-D-glucoside[periplasmic space] + HPr-Phis15 → methyl β-D-glucoside 6-phosphate[cytosol] + HPr ,
Cu2+[periplasmic space] → Cu2+[cytosol] ,
β-D-fructofuranose 6-phosphate[periplasmic space] + phosphate[cytosol] → β-D-fructofuranose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
selenite[periplasmic space] + ATP + H2O → selenite[cytosol] + ADP + phosphate + H+ ,
urea[cytosol] ↔ urea[periplasmic space] ,
D-fructosyl-L-lysine[periplasmic space] → D-fructosyl-L-lysine[cytosol] ,
L-leucine[cytosol] + H+[periplasmic space] → L-leucine[periplasmic space] + H+[cytosol] ,
N-acetyl-β-neuraminate[extracellular space]N-acetyl-β-neuraminate[periplasmic space] ,
ATP + a dipeptide[periplasmic space] + H2O → ADP + a dipeptide[cytosol] + phosphate + H+ ,
pyridoxal[periplasmic space] → pyridoxal[cytosol] ,
Na+[periplasmic space] + melibiose[periplasmic space] → Na+[cytosol] + melibiose[cytosol] ,
D-alanine[periplasmic space] + H+[periplasmic space] → D-alanine[cytosol] + H+[cytosol] ,
shikimate[periplasmic space] + H+[periplasmic space] → shikimate[cytosol] + H+[cytosol] ,
β-D-galactose[periplasmic space] + H+[periplasmic space] → β-D-galactose[cytosol] + H+[cytosol] ,
uracil[periplasmic space] + H+[periplasmic space] → uracil[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + L-proline[periplasmic space] → Na+[cytosol] + L-proline[cytosol] ,
a C4-dicarboxylate[periplasmic space] + 3 H+[periplasmic space] → a C4-dicarboxylate[cytosol] + 3 H+[cytosol] ,
1,6-anhydro-N-acetyl-β-muramate[periplasmic space] → 1,6-anhydro-N-acetyl-β-muramate[cytosol] ,
lactate[cytosol] ↔ lactate[periplasmic space] ,
ferric dicitrate[extracellular space] → ferric dicitrate[cytosol] ,
arsenite[periplasmic space] ↔ arsenite[cytosol] ,
acetate[periplasmic space] → acetate[cytosol] ,
glycine betaine[cytosol] + 2 H+[periplasmic space] → glycine betaine[periplasmic space] + 2 H+[cytosol] ,
D-cystine[periplasmic space] → D-cystine[cytosol] ,
Zn2+[periplasmic space] → Zn2+[cytosol] ,
fluoride[cytosol] → fluoride[periplasmic space] ,
d-biotin d-sulfoxide[periplasmic space]d-biotin d-sulfoxide[cytosol] ,
cobinamide[extracellular space] → cobinamide[cytosol] ,
phenylacetaldehyde[periplasmic space] → phenylacetaldehyde[cytosol] ,
a tripeptide[periplasmic space] + H+[periplasmic space] → a tripeptide[cytosol] + H+[cytosol] ,
putrescine[cytosol] + L-ornithine[periplasmic space] → putrescine[periplasmic space] + L-ornithine[cytosol] ,
Ag+[cytosol] + H+[periplasmic space] → Ag+[extracellular space] + H+[cytosol] ,
4-aminobutanoate[periplasmic space] + H+[periplasmic space] → 4-aminobutanoate[cytosol] + H+[cytosol] ,
nitrite[cytosol] + H+[periplasmic space] → nitrite[periplasmic space] + H+[cytosol] ,
Na+[cytosol] + 2 H+[periplasmic space] → Na+[periplasmic space] + 2 H+[cytosol] ,
phosphate[periplasmic space] + H+[periplasmic space] → phosphate[cytosol] + H+[cytosol] ,
succinate[cytosol] + fumarate[periplasmic space] → fumarate[cytosol] + succinate[periplasmic space] ,
Ni2+[cytosol] → Ni2+[periplasmic space] ,
a drug[cytosol] + Na+[periplasmic space] → a drug[periplasmic space] + Na+[cytosol] ,
GMP[cytosol] → GMP[periplasmic space] ,
guanosine[cytosol] + H+[periplasmic space] → guanosine[periplasmic space] + H+[cytosol] ,
H2O[periplasmic space] ↔ H2O[cytosol] ,
O-acetyl-L-serine[cytosol]O-acetyl-L-serine[periplasmic space] ,
benzene-1,4-diol[cytosol] → benzene-1,4-diol[periplasmic space] ,
L-methionine S-oxide[periplasmic space] + ATP + H2O → L-methionine S-oxide[cytosol] + ADP + phosphate + H+ ,
D-serine[periplasmic space] → D-serine[cytosol] ,
phosphate[cytosol] → phosphate[periplasmic space] ,
p-aminobenzoyl glutamate[periplasmic space] + H+[periplasmic space]p-aminobenzoyl glutamate[cytosol] + H+[cytosol] ,
acetoacetate[periplasmic space] → acetoacetate[cytosol] ,
arsenite[cytosol] + H+[periplasmic space] → arsenite[periplasmic space] + H+[cytosol] ,
pyruvate[in] + 2 H+[in] + 2 e- → (S)-lactate[in] ,
ammonium[periplasmic space] ↔ ammonium[cytosol] ,
D-galactarate[periplasmic space] → D-galactarate[cytosol] ,
D-fructuronate[periplasmic space] + H+[periplasmic space] → D-fructuronate[cytosol] + H+[cytosol] ,
4 H+[in] → 4 H+[out] ,
K+[cytosol] + H+[periplasmic space] → K+[periplasmic space] + H+[cytosol] ,
H2O[periplasmic space] ↔ H2O[cytosol] ,
Na+[periplasmic space] + L-valine[periplasmic space] → Na+[cytosol] + L-valine[cytosol] ,
uridine[periplasmic space] + H+[periplasmic space] → uridine[cytosol] + H+[cytosol] ,
Na+[cytosol] + H+[periplasmic space] → Na+[periplasmic space] + H+[cytosol] ,
guanine[periplasmic space] → guanine[cytosol] ,
2 chloride[periplasmic space] + H+[cytosol] ↔ 2 chloride[cytosol] + H+[periplasmic space] ,
hypoxanthine[cytosol] ← hypoxanthine[periplasmic space] ,
cob(I)alamin[extracellular space] → cob(I)alamin[cytosol] ,
ammonia[periplasmic space] ↔ ammonia[cytosol] ,
methane[cytosol] → methane[periplasmic space] ,
Mn2+[periplasmic space] → Mn2+[cytosol] ,
djenkolate[periplasmic space] → djenkolate[cytosol] ,
(R)-propane-1,2-diol[cytosol] → (R)-propane-1,2-diol[periplasmic space] ,
1-deoxy-D-xylulose[periplasmic space] → 1-deoxy-D-xylulose[cytosol] ,
(R)-lipoate[periplasmic space] → (R)-lipoate[cytosol] ,
biotin[periplasmic space] → biotin[cytosol] ,
Zn2+[cytosol] + H+[periplasmic space] → Zn2+[periplasmic space] + H+[cytosol] ,
L-tryptophan[periplasmic space] + H+[periplasmic space] → L-tryptophan[cytosol] + H+[cytosol] ,
D-glucuronate[periplasmic space] + H+[periplasmic space] → D-glucuronate[cytosol] + H+[cytosol] ,
Mn2+[periplasmic space] + H+[periplasmic space] → Mn2+[cytosol] + H+[cytosol] ,
α-D-mannose[periplasmic space] + HPr-Phis15 → α-D-mannose 6-phosphate[cytosol] + HPr ,
indole[periplasmic space] + H+[periplasmic space] → indole[cytosol] + H+[cytosol] ,
D-galacturonate[periplasmic space] + H+[periplasmic space] → D-galacturonate[cytosol] + H+[cytosol] ,
2'-deoxyuridine[periplasmic space] + H+[periplasmic space] → 2'-deoxyuridine[cytosol] + H+[cytosol] ,
formate[cytosol] ↔ formate[periplasmic space] ,
maltose[periplasmic space] → maltose[cytosol] ,
dihydroxyacetone[periplasmic space] → dihydroxyacetone[cytosol] ,
ethidium[cytosol] → ethidium[periplasmic space] ,
non-specific ion/solute[extracellular space] → non-specific ion/solute[periplasmic space] ,
D-glycerate[periplasmic space] → D-glycerate[cytosol] ,
enterobactin[cytosol] → enterobactin[extracellular space] ,
propanoate[periplasmic space] → propanoate[cytosol] ,
Mn2+[cytosol] → Mn2+[periplasmic space] ,
4-methyl-5-(β-hydroxyethyl)thiazole[periplasmic space] → 4-methyl-5-(β-hydroxyethyl)thiazole[cytosol] ,
N,N'-diacetylchitobiose[extracellular space]N,N'-diacetylchitobiose[periplasmic space] ,
partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine[periplasmic space] → partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine[extracellular space] ,
Na+[periplasmic space] + 2,3-dioxo-L-gulonate[periplasmic space] → Na+[cytosol] + 2,3-dioxo-L-gulonate[cytosol] ,
aldehydo-L-galactonate[periplasmic space] + H+[periplasmic space]aldehydo-L-galactonate[cytosol] + H+[cytosol] ,
L-threonine[cytosol] + H+[periplasmic space] → L-threonine[periplasmic space] + H+[cytosol] ,
D-cycloserine[periplasmic space] + H+[periplasmic space] → D-cycloserine[cytosol] + H+[cytosol] ,
ATP + arsenate[cytosol] + H2O → ADP + arsenate[periplasmic space] + phosphate + H+ ,
D-xylose[periplasmic space] + H+[periplasmic space] → D-xylose[cytosol] + H+[cytosol] ,
glycolate[periplasmic space] → glycolate[cytosol] ,
a lipopolysaccharide[cytosol] → a lipopolysaccharide[extracellular space] ,
D-galactonate[periplasmic space] + H+[periplasmic space] → D-galactonate[cytosol] + H+[cytosol] ,
Mg2+[periplasmic space] → Mg2+[cytosol] ,
orotate[periplasmic space] + 2 H+[periplasmic space] → orotate[cytosol] + 2 H+[cytosol] ,
2'-deoxyadenosine[periplasmic space] + H+[periplasmic space] → 2'-deoxyadenosine[cytosol] + H+[cytosol] ,
chenodeoxycholate[periplasmic space] → chenodeoxycholate[cytosol] ,
hydrogen peroxide[periplasmic space] → hydrogen peroxide[extracellular space] ,
carbon monoxide[periplasmic space] ↔ carbon monoxide[cytosol] ,
DL-glyceraldehyde[periplasmic space] ↔ DL-glyceraldehyde[cytosol] ,
maltose[extracellular space] → maltose[periplasmic space] ,
methyl-α-D-galactopyranoside[periplasmic space] + H+[periplasmic space] → methyl-α-D-galactopyranoside[cytosol] + H+[cytosol] ,
α-D-mannose 6-phosphate[periplasmic space] + phosphate[cytosol] → α-D-mannose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
L-selenocysteine[periplasmic space] → L-selenocysteine[cytosol] ,
S-methyl-5-thio-D-ribose[cytosol]S-methyl-5-thio-D-ribose[periplasmic space] ,
psicoselysine[periplasmic space] → psicoselysine[cytosol] ,
octanoate[periplasmic space] → octanoate[cytosol] ,
Li+[periplasmic space] + melibiose[periplasmic space] → Li+[cytosol] + melibiose[cytosol] ,
glycine[periplasmic space] + H+[periplasmic space] → glycine[cytosol] + H+[cytosol] ,
L-proline[periplasmic space] + H+[periplasmic space] → L-proline[cytosol] + H+[cytosol] ,
sn-glycerol 3-phosphate[periplasmic space] + phosphate[cytosol]sn-glycerol 3-phosphate[cytosol] + phosphate[periplasmic space] ,
nitrite[periplasmic space] → nitrite[cytosol] ,
succinate[periplasmic space] + 2 H+[periplasmic space] → succinate[cytosol] + 2 H+[cytosol] ,
a nucleoside[periplasmic space] + H+[periplasmic space] → a nucleoside[cytosol] + H+[cytosol] ,
cholate[cytosol] + H+[periplasmic space] → cholate[periplasmic space] + H+[cytosol] ,
an L-amino acid[cytosol] → an L-amino acid[periplasmic space] ,
succinate[periplasmic space] → succinate[cytosol] ,
glyoxylate[periplasmic space] → glyoxylate[cytosol] ,
choline[cytosol] + 2 H+[periplasmic space] → choline[periplasmic space] + 2 H+[cytosol] ,
ferrichrome[extracellular space] → ferrichrome[periplasmic space] ,
(R)-lactate[periplasmic space] + H+[periplasmic space] → (R)-lactate[cytosol] + H+[cytosol] ,
D-tartrate[periplasmic space] + succinate[cytosol] → succinate[periplasmic space] + D-tartrate[cytosol] ,
ethanolamine[periplasmic space] → ethanolamine[cytosol] ,
3-hydroxy-trans-cinnamate[periplasmic space] + H+[periplasmic space] → 3-hydroxy-trans-cinnamate[cytosol] + H+[cytosol] ,
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[cytosol]ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[periplasmic space] ,
ATP + L-alanyl-γ-D-glutamyl-meso-diaminopimelate[periplasmic space] + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate[cytosol] + ADP + phosphate + H+ ,
ATP + L-proline[periplasmic space] + H2O → ADP + L-proline[cytosol] + phosphate + H+ ,
cadaverine[periplasmic space] + H+[periplasmic space] → cadaverine[cytosol] + H+[cytosol] ,
a drug[cytosol] + H+[periplasmic space] → a drug[extracellular space] + H+[cytosol] ,
L-lysine[periplasmic space] + H+[periplasmic space] → L-lysine[cytosol] + H+[cytosol] ,
4-aminobutanoate[cytosol] + L-glutamate[periplasmic space] → L-glutamate[cytosol] + 4-aminobutanoate[periplasmic space] ,
L-fucose[periplasmic space] + H+[periplasmic space] → L-fucose[cytosol] + H+[cytosol] ,
HPr-Phis15 + β-D-cellobiose[periplasmic space] → β-D-cellobiose 6'-phosphate[cytosol] + HPr ,
Na+[periplasmic space] + L-serine[periplasmic space] → Na+[cytosol] + L-serine[cytosol] ,
2 Na+[cytosol] + 3 H+[periplasmic space] → 2 Na+[periplasmic space] + 3 H+[cytosol] ,
cytosine[periplasmic space] + H+[periplasmic space] → cytosine[cytosol] + H+[cytosol] ,
succinate[cytosol] + L-aspartate[periplasmic space] → L-aspartate[cytosol] + succinate[periplasmic space] ,
Co2+[cytosol] → Co2+[periplasmic space] ,
IMP[cytosol] → IMP[periplasmic space] ,
poly-β-1,6-N-acetyl-D-glucosamine[cytosol] → poly-β-1,6-N-acetyl-D-glucosamine[periplasmic space] ,
L-cysteine[cytosol] → L-cysteine[periplasmic space] ,
urate[periplasmic space] + H+[periplasmic space] → urate[cytosol] + H+[cytosol] ,
ferric enterobactin complex[extracellular space] → ferric enterobactin complex[periplasmic space] ,
L-cystathionine[periplasmic space] → L-cystathionine[cytosol] ,
enterobactin[cytosol] → enterobactin[periplasmic space] ,
acetylmaltose[cytosol] → acetylmaltose[extracellular space] ,
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[cytosol] → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[periplasmic space] ,
3-phenylpropanoate[periplasmic space] → 3-phenylpropanoate[cytosol] ,
an aromatic amino acid[cytosol] → an aromatic amino acid[periplasmic space] ,
Cu+[cytosol] + ATP + H2O → Cu+[periplasmic space] + ADP + phosphate + H+ ,
D-glucarate[periplasmic space] → D-glucarate[cytosol] ,
α-lactose[cytosol] + H+[periplasmic space] → α-lactose[periplasmic space] + H+[cytosol] ,
a drug[cytosol] + H+[periplasmic space] → a drug[periplasmic space] + H+[cytosol] ,
N-acetylneuraminate[periplasmic space] + H+[periplasmic space]N-acetylneuraminate[cytosol] + H+[cytosol] ,
ATP + L-methionine[periplasmic space] + H2O → ADP + L-methionine[cytosol] + phosphate + H+ ,
an O-antigen[cytosol] → an O-antigen[periplasmic space] ,
Na+[periplasmic space] + L-leucine[periplasmic space] → Na+[cytosol] + L-leucine[cytosol] ,
L-rhamnose[periplasmic space] + H+[periplasmic space] → L-rhamnose[cytosol] + H+[cytosol] ,
(S)-lactate[periplasmic space] + H+[periplasmic space] → (S)-lactate[cytosol] + H+[cytosol] ,
hypoxanthine[cytosol] → hypoxanthine[periplasmic space] ,
indole[cytosol] ↔ indole[periplasmic space] ,
agmatine[cytosol] + L-arginine[periplasmic space] → agmatine[periplasmic space] + L-arginine[cytosol] ,
CO2[periplasmic space] ↔ CO2[cytosol] ,
cholate[periplasmic space] → cholate[cytosol] ,
hypotaurine[periplasmic space] → hypotaurine[cytosol] ,
N-acetylneuraminate[extracellular space]N-acetylneuraminate[periplasmic space] ,
a nucleoside[extracellular space] → a nucleoside[periplasmic space] ,
N-(2,3-dihydroxybenzoyl)-L-serine[cytosol]N-(2,3-dihydroxybenzoyl)-L-serine[extracellular space] ,
xanthine[periplasmic space] + H+[periplasmic space] → xanthine[cytosol] + H+[cytosol] ,
N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol[cytosol]N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol[periplasmic space] ,
Cd2+[cytosol] + H+[periplasmic space] → Cd2+[periplasmic space] + H+[cytosol] ,
succinate[cytosol] + citrate[periplasmic space] → citrate[cytosol] + succinate[periplasmic space] ,
L-tyrosine[periplasmic space] + H+[periplasmic space] → L-tyrosine[cytosol] + H+[cytosol] ,
L-arabinose[cytosol] + H+[periplasmic space] → L-arabinose[periplasmic space] + H+[cytosol] ,
L-homoserine[cytosol] + H+[periplasmic space] → L-homoserine[periplasmic space] + H+[cytosol] ,
HPr-Phis15 + N-acetyl-β-D-glucosamine[periplasmic space]N-acetyl-D-glucosamine 6-phosphate[cytosol] + HPr ,
K+[periplasmic space] → K+[cytosol] ,
Na+[periplasmic space] + L-alanine[periplasmic space] → Na+[cytosol] + L-alanine[cytosol] ,
inosine[periplasmic space] + H+[periplasmic space] → inosine[cytosol] + H+[cytosol] ,
L-cysteine[cytosol] + ATP + H2O → L-cysteine[periplasmic space] + ADP + phosphate + H+ ,
L-arabinose[periplasmic space] + H+[periplasmic space] → L-arabinose[cytosol] + H+[cytosol] ,
tellurite[periplasmic space] → tellurite[cytosol] ,
uracil[cytosol] → uracil[periplasmic space] ,
thymine[cytosol] → thymine[periplasmic space] ,
pyruvate[periplasmic space] → pyruvate[cytosol] ,
ferric coprogen[extracellular space] → ferric coprogen[cytosol] ,
3-hydroxypropanoate[cytosol] → 3-hydroxypropanoate[extracellular space] ,
N-acetyl-β-D-mannosamine[periplasmic space] + HPr-Phis15N-acetyl-D-mannosamine 6-phosphate[cytosol] + HPr ,
4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[cytosol] → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[periplasmic space] ,
β-L-lyxopyranose[periplasmic space] + H+[periplasmic space] → β-L-lyxopyranose[cytosol] + H+[cytosol] ,
ATP + L-leucine[periplasmic space] + H2O → ADP + L-leucine[cytosol] + phosphate + H+ ,
ATP + L-isoleucine[periplasmic space] + H2O → ADP + L-isoleucine[cytosol] + phosphate + H+ ,
5-dehydro-D-gluconate[periplasmic space] + H+[periplasmic space] → 5-dehydro-D-gluconate[cytosol] + H+[cytosol] ,
L-serine[periplasmic space] + H+[periplasmic space] → L-serine[cytosol] + H+[cytosol] ,
xanthosine[periplasmic space] + H+[periplasmic space] → xanthosine[cytosol] + H+[cytosol] ,
an aminoalkylphosphonate[periplasmic space] + ATP + H2O → an aminoalkylphosphonate[cytosol] + ADP + phosphate + H+ ,
Co2+[periplasmic space] → Co2+[cytosol] ,
2 Na+[periplasmic space] + L-glutamate[periplasmic space] → 2 Na+[cytosol] + L-glutamate[cytosol] ,
2'-deoxycytidine[periplasmic space] + H+[periplasmic space] → 2'-deoxycytidine[cytosol] + H+[cytosol] ,
chenodeoxycholate[cytosol] + H+[periplasmic space] → chenodeoxycholate[periplasmic space] + H+[cytosol] ,
a glycerophosphodiester[periplasmic space] + ATP + H2O → a glycerophosphodiester[cytosol] + ADP + phosphate + H+ ,
allantoin[periplasmic space] → allantoin[cytosol] ,
glycine[periplasmic space] ↔ glycine[cytosol] ,
inosine[cytosol] + H+[periplasmic space] → inosine[periplasmic space] + H+[cytosol] ,
methyl-β-D-galactoside[periplasmic space] + Na+[periplasmic space] → methyl-β-D-galactoside[cytosol] + Na+[cytosol] ,
D-glucopyranose[periplasmic space] + H+[periplasmic space] → D-glucopyranose[cytosol] + H+[cytosol] ,
1-(β-D ribofuranosyl)nicotinamide[periplasmic space] → 1-(β-D ribofuranosyl)nicotinamide[cytosol] ,
hydroxymethylpyrimidine[periplasmic space] → hydroxymethylpyrimidine[cytosol] ,
a long-chain fatty acid[periplasmic space] → a long-chain fatty acid[cytosol] ,
dimethyl sulfoxide[periplasmic space] → dimethyl sulfoxide[cytosol] ,
ATP + thiamin[periplasmic space] + H2O → ADP + thiamin[cytosol] + phosphate + H+ ,
acetate[in] + CO2[in] + 2 H+[in] + 2 e- → pyruvate[in] + H2O[in] ,
a macrolide antibiotic[cytosol] + ATP + H2O → a macrolide antibiotic[extracellular space] + ADP + phosphate ,
S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+ ,
β-D-galactofuranose[periplasmic space] + ATP + H2O → β-D-galactofuranose[cytosol] + ADP + phosphate + H+ ,
hydroquinone-O-β-D-glucopyranoside[periplasmic space] + HPr-Phis15 → arbutin-6-phosphate[cytosol] + HPr ,
tetrahydrothiophene 1-oxide[periplasmic space] + a reduced electron acceptor[periplasmic space] → tetrahydrothiophene[periplasmic space] + an oxidized electron acceptor[periplasmic space] + H2O[periplasmic space] ,
2-amino-3-oxobutanoate + 2 H+ → aminoacetone + CO2 ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
fructoselysine 6-phosphate + H2O ↔ β-D-glucose 6-phosphate + L-lysine ,
D-fructosyl-L-lysine + ATP → fructoselysine 6-phosphate + ADP + H+ ,
L-alanyl-γ-D-glutamyl-meso-diaminopimelate + H2O → L-alanyl-D-glutamate + meso-diaminopimelate ,
N6-L-threonylcarbamoyladenine37 in tRNA + ATP = cyclic N6-L-threonylcarbamoyladenosine 37 in tRNA + ADP + phosphate ,
phenylacetyl-CoA + H2O = phenylacetate + coenzyme A + H+ ,
2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA + H2O = 2-hydroxycyclohepta-1,4,6-triene-1-carboxylate + coenzyme A ,
3-oxo-5,6-didehydrosuberyl-CoA semialdehyde → 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA + H2O ,
D-gluconate + NAD+ ↔ 5-dehydro-D-gluconate + NADH + H+ ,
a tRNA 2-thiouridine34 + a 5,10-methylene-tetrahydrofolate + ammonium + GTP + H2O → a tRNA containing 5-aminomethyl-2-thiouridine + a 7,8-dihydrofolate + GDP + phosphate ,
a tRNA 2-thiouridine34 + GTP + glycine + a 5,10-methylene-tetrahydrofolate + H2O = a tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + GDP + a 7,8-dihydrofolate + phosphate ,
a tRNA containing 5-carboxymethylaminomethyl-2-thiouridine → a tRNA containing 5-aminomethyl-2-thiouridine + glyoxylate ,
CTP + hydroxyl radical → 5-hydroxy-CTP + H+ ,
m7GTP + H2O → N7-methylguanosine 5'-phosphate + diphosphate + H+ ,
a [protein] acetyl-L-lysine + NAD+ + H2O → a [protein]-L-lysine + 3''-O-acetyl-ADP-ribose + nicotinamide ,
pyridoxamine 5'-phosphate + a deaminated amino group acceptor ↔ pyridoxal 5'-phosphate + an aminated amino group acceptor ,
a tRNA uridine34 + GTP + a 5,10-methylene-tetrahydrofolate + glycine + H2O = a tRNA containing 5-carboxymethylaminomethyluridine + GDP + a 7,8-dihydrofolate + phosphate ,
a 5-hydroxyuridine34 in tRNA + carboxy-S-adenosyl-L-methionine → a 5-(carboxymethoxy)uridine34 in tRNA + S-adenosyl-L-homocysteine + H+ ,
prephenate + S-adenosyl-L-methionine → 2-oxo-3-phenylpropanoate + carboxy-S-adenosyl-L-methionine + H2O ,
3-keto-L-gulonate + ATP → 3-keto-L-gulonate 6-phosphate + ADP + H+ ,
aminomethylphosphonate + acetyl-CoA = 2-N-acetamidomethylphosphonate + coenzyme A ,
an O-acetyl-ADP-ribose + H2O = ADP-D-ribose + acetate ,
an L-1-phosphatidyl-glycerol + an L-1-phosphatidyl-ethanolamine → a cardiolipin + ethanolamine ,
GS-methylhydroquinone + glutathione = methyl-p-hydroquinone + glutathione disulfide ,
3-mercaptopyruvate → pyruvate + hydrogen sulfide ,
(2,3-dihydroxybenzoylserine)3 + 2 H2O = 3 N-(2,3-dihydroxybenzoyl)-L-serine + 2 H+ ,
L-methionine + hydrogen peroxide → L-methionine S-oxide + H2O ,
3-hydroxy-2,4-pentadione 5-phosphate + H2O = 3,4,4-trihydroxy-2-pentanone 5-phosphate ,
isoguanine + H+ + H2O → xanthine + ammonium ,
dihydrocurcumin + NADPH + H+ → tetrahydrocurcumin + NADP+ ,
curcumin + NADPH + H+ → dihydrocurcumin + NADP+ ,
3-phospho-hydroxypyruvate + H2O → hydroxypyruvate + phosphate ,
5'-deoxyadenosine + H2O → 5-deoxy-D-ribose + adenine ,
bromoacetate + glutathione = glutathione-S-acetate + bromide + H+ ,
D-sedoheptulose 7-phosphate + ATP → D-sedoheptulose-1,7-bisphosphate + ADP + H+ ,
(Z)-3-peroxyaminoacrylate + a reduced electron acceptor → aminoacrylate + an oxidized electron acceptor + H2O + H+ ,
(Z)-3-ureidoacrylate peracid + H2O → carbamate + (Z)-3-peroxyaminoacrylate + H+ ,
aminoacrylate + H+ + H2O → malonate semialdehyde + ammonium ,
3-ureidoacrylate + H2O → carbamate + aminoacrylate + H+ ,
(Z)-3-ureidoacrylate peracid + NADH → 3-ureidoacrylate + NAD+ + H2O ,
β-D-glucose[periplasmic space] ↔ D-glucose[periplasmic space] ,
7,8-dihydromonapterin triphosphate + 3 H2O → 7,8-dihydromonapterin + 3 phosphate + 2 H+ ,
2-hydroxyethyldisulfide + 2 glutathione = 2 2-mercaptoethanol + glutathione disulfide ,
(S)-4,5-dihydroxypentan-2,3-dione + ATP → 4-hydroxy-2,3-pentanedione 5-phosphate + ADP + H+ ,
4-hydroxy-2,3-pentanedione 5-phosphate = 2-phosphoglycolate + an unknown C3 fragment ,
poly-β-1,6-N-acetyl-D-glucosamine + H2O = partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine + acetate + H+ ,
UDP-N-acetyl-α-D-glucosamine = poly-β-1,6-N-acetyl-D-glucosamine + UDP ,
4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + H2O → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + formate ,
peptidoglycan tetrapeptide, glycan chain 2 + peptidoglycan tetrapeptide, glycan chain 1 → peptidoglycan DAP-DAP crosslink + D-alanine + H+ ,
2-trans,5-cis-tetradecadienoyl-CoA + H2O → 3-hydroxy-5-cis-tetradecenoyl-CoA ,
lipid A-core + di-trans,octa-cis-undecaprenyl diphosphate + H+ = lipid A-core 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate ,
GDP-L-fucose + UDP-D-glucose + UDP-α-D-glucuronate + UDP-α-D-galactose = colanic acid ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
lipid A-core[periplasmic space] + colanic acid[periplasmic space] → MLPS[periplasmic space] + H2O[periplasmic space] ,
D-alanine + pyridoxal 5'-phosphate ↔ pyruvate + pyridoxamine 5'-phosphate ,
aldehydo-L-galactonate + NAD+ → D-tagaturonate + NADH + H+ ,
an L-1-phosphatidyl-glycerol + ATP → an L-1-phosphatidylglycerol-phosphate + ADP + H+ ,
carbamate + 2 H+ → ammonium + CO2 ,
H+ + OH- ↔ H2O ,
a lipopolysaccharide + dTDP-β-L-rhamnose = a rhamnosyl lipopolysaccharide + dTDP ,
a lipopolysaccharide + CMP-3-deoxy-D-manno-octulosonate = KDOIII-lipopolysaccharide + CMP ,
GDP-α-D-mannose + H2O → GMP + α-D-mannose 1-phosphate + 2 H+ ,
3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + coenzyme A + H+ ,
α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + ADP-L-glycero-β-D-manno-heptose = heptosyl-Kdo2-lipid IVA + ADP + H+ ,
D-fructosyl-L-lysine ↔ psicoselysine ,
an L-1-phosphatidyl-ethanolamine[periplasmic space] + α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA[periplasmic space] = a 1,2-diacyl-sn-glycerol[periplasmic space] + phosphatidylethanolamine-KDO2-lipidA[periplasmic space] ,
a 1,2-diacyl-sn-glycerol 3-diphosphate[periplasmic space] + H2O[periplasmic space] → a 1,2-diacyl-sn-glycerol 3-phosphate[periplasmic space] + phosphate[periplasmic space] + H+[periplasmic space] ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
γ-glutamyl-L-putrescine + H2O + oxygen → 4-(γ-glutamylamino)butanal + hydrogen peroxide + ammonium ,
4-amino-2-methyl-5-diphosphomethylpyrimidine + H2O → 4-amino-2-methyl-5-phosphomethylpyrimidine + phosphate + H+ ,
Cr6+ + 2 NAD(P)H + oxygen → Cr3+ + hydrogen peroxide + 2 NAD(P)+ ,
2,3-dihydroxybenzoate[periplasmic space] + oxygen[periplasmic space] → 2-carboxymuconate[periplasmic space] + 2 H+[periplasmic space] ,
a 5-methylaminomethyl-2-thiouridine in tRNA + selenophosphate → tRNA containing 5-methylaminomethyl-2-selenouridine + unknown product ,
glutathione[cytosol] + ATP + H2O → glutathione[periplasmic space] + ADP + phosphate + H+ ,
UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O → D-alanine + UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate ,
pyruvate + acetaldehyde + H+ → acetoin + CO2 ,
a phospholipid + (KDO)2-lipid A → a glycerol ester + hepta-acylated KDO2-lipid A ,
α-D-ribose-1-phosphate + ATP → α-D-ribose 1,5-bisphosphate + ADP + H+ ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
(2R,3S)-3-isopropylmalate ← 2-isopropylmaleate + H2O ,
2-aminoprop-2-enoate + H+ + H2O → pyruvate + ammonium ,
S-adenosyl-L-methionine + precorrin-1 → S-adenosyl-L-homocysteine + precorrin-2 ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
(S)-propane-1,2-diol + NAD+ ↔ acetol + NADH + H+ ,
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + H+ → 3-amino-1-hydroxyacetone 1-phosphate + CO2 ,
sulfite + H+ ↔ bisulfite ,
heme b + hydrogen peroxide = heme d ,
(2S)-2-isopropyl-3-oxosuccinate + H+ → 4-methyl-2-oxopentanoate + CO2 ,
(2E)-2-hydroxypenta-2,4-dienoate ↔ 2-oxopent-4-enoate ,
a 5,10-methenyltetrahydrofolate + H2O = an N5-formyl-tetrahydrofolate + H+ ,
betaine aldehyde hydrate ↔ betaine aldehyde + H2O ,
(S)-2-acetolactate + an oxidized electron acceptor + H+ → diacetyl + CO2 + a reduced electron acceptor ,
2 monodehydroascorbate radical → L-ascorbate + L-dehydro-ascorbate + H+ ,
2 L-ascorbate + hydrogen peroxide + 2 H+ → 2 monodehydroascorbate radical + 2 H2O ,
formaldehyde + a tetrahydrofolate → a 5,10-methylene-tetrahydrofolate + H2O ,
D-serine → 2-aminoprop-2-enoate + H2O + H+ ,
L-tryptophan → indole + 2-aminoprop-2-enoate + H+ ,
keto-L-rhamnulose → L-rhamnulofuranose ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
β-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
α-D-ribose 5-phosphate → β-D-ribose 5-phosphate ,
2 Fe2+ + hydrogen peroxide + 2 H2O = 2 [FeO(OH)] monomer + 4 H+ ,
2 Fe2+ + oxygen + 4 H2O = 2 [FeO(OH)] monomer + hydrogen peroxide + 4 H+ ,
an E. coli osmoregulated periplasmic glucan (OPG)[periplasmic space] + an L-1-phosphatidyl-ethanolamine[periplasmic space] → an E. coli osmoregulated periplasmic glucan with phosphotidylethanolamine substituent[periplasmic space] + a 1,2-diacyl-sn-glycerol[periplasmic space] ,
O-succinyl-L-homoserine → succinate + (2Z)-2-aminobut-2-enoate + 2 H+ ,
2'-deoxyadenosine + hydroxyl radical → 2-hydroxydeoxyadenosine + H+ ,
adenine + hydroxyl radical → isoguanine + H+ ,
L-cystathionine → 2-aminoprop-2-enoate + L-homocysteine + H+ ,
L-cysteine → 2-aminoprop-2-enoate + hydrogen sulfide + H+ ,
L-serine → 2-aminoprop-2-enoate + H+ + H2O ,
2-aminoprop-2-enoate → 2-iminopropanoate ,
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
α-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
aldehydo-D-ribose ↔ D-ribopyranose ,
aldehydo-D-ribose ↔ D-ribofuranose ,
D-altropyranose ↔ aldehydo-D-altrose ,
aldehydo-L-fucose ↔ L-fucopyranose ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
keto-L-sorbose ↔ L-sorbopyranose ,
D-tagatofuranose ↔ keto-D-tagatose ,
L-arabinofuranose ↔ L-arabinopyranose ,
aldehydo-L-arabinose ↔ L-arabinopyranose ,
D-arabinofuranose ↔ D-arabinopyranose ,
D-arabinopyranose → aldehydo-D-arabinose ,
D-galactopyranuronate ↔ aldehydo-D-galacturonate ,
D-allopyranose ↔ aldehydo-D-allose ,
D-glucopyranuronate ↔ aldehydo-D-glucuronate ,
O-phospho-L-tyrosine[periplasmic space] + H2O[periplasmic space] → L-tyrosine[periplasmic space] + phosphate[periplasmic space] ,
keto-D-fructose → β-D-fructofuranose ,
aldehydo-D-xylose ↔ a D-xylopyranose ,
aldehydo-D-mannose → β-D-mannose ,
aldehydo-D-mannose → D-mannopyranose ,
2-thio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine + a sulfurated [sulfur carrier] = 2-thio-N6-dimethylallyladenosine37 in tRNA + an unsulfurated [sulfur carrier] + L-methionine + 5'-deoxyadenosine ,
a nucleoside 5'-monophosphate[periplasmic space] + H2O[periplasmic space] → a nucleoside[periplasmic space] + phosphate[periplasmic space] ,
aldehydo-D-galactose → D-galactopyranose ,
aldehydo-D-glucose → D-glucopyranose ,
hydroxymethylbilane → uroporphyrinogen-I + H2O ,
an [L-cysteine desulfurase] L-cysteine persulfide + a ThiI sulfur-carrier protein → an [L-cysteine desulfurase]-L-cysteine + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
an L-1-phosphatidyl-ethanolamine[periplasmic space] + lipid A-core[periplasmic space] → a 1,2-diacyl-sn-glycerol[periplasmic space] + lipid A-core-1-pyrophosphoethanolamine[periplasmic space] ,
an L-1-phosphatidyl-ethanolamine[periplasmic space] + lipid A-core[periplasmic space] → a 1,2-diacyl-sn-glycerol[periplasmic space] + lipid A-core-phosphoethanolamine (hep II)[periplasmic space] ,
ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+ ,
dATP + hydroxyl radical → 2-hydroxy-dATP + H+ ,
(R)-3-hydroxybutanoyl-CoA + H2O → (R)-3-hydroxybutanoate + coenzyme A + H+ ,
(S)-3-hydroxybutanoyl-CoA + H2O → (S)-3-hydroxybutanoate + coenzyme A + H+ ,
(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate → (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
(2Z)-2-hydroxypenta-2,4-dienoate ↔ 2-oxopent-4-enoate ,
4-hydroxy-2-oxopentanoate → (2Z)-2,4-dihydroxypent-2-enoate ,
2-oxopent-4-enoate ↔ (3Z)-2-oxopent-3-enoate ,
2-iminoacetate + H+ + H2O → glyoxylate + ammonium ,
(Z)-2-methylureidoacrylate peracid + H2O → (Z)-2-methyl-peroxyaminoacrylate + carbamate + H+ ,
cyclic-2,3-O-oxalyl-L-threonate → cyclic- 3,4-O-oxalyl-L-threonate ,
2-carboxy-L-xylonolactone + H2O → 2-carboxy-L-threo-pentonate + H+ ,
2,3-dioxo-L-gulonate → 2-carboxy-L-xylonolactone ,
2 L-dehydro-ascorbate + oxygen → 2 cyclic-2,3-O-oxalyl-L-threonate + 2 H+ ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
L-dehydro-ascorbate + H2O → dehydroascorbate (bicyclic form) ,
dehydroascorbate (bicyclic form) → 2,3-dioxo-L-gulonate + H+ ,
NADH + H2O → (R)-NADHX ,
NADH + H2O → (S)-NADHX ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
2 Fe2+ + 2 oxygen → 2 superoxide + 2 Fe3+ ,
hydrogen peroxide + Fe2+ → hydroxyl radical + Fe3+ + OH- ,
2-oxo-4-methylthiobutanoate + hydroxyl radical → ethylene + methanethiol + 2 CO2 ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate ,
L-rhamnopyranose ↔ L-rhamnofuranose ,
ammonia + H+ ↔ ammonium ,
dGTP + hydroxyl radical → 8-oxo-dGTP + H+ ,
GTP + hydroxyl radical → 8-oxo-GTP + H+ ,
L-ascorbate + an oxidized electron acceptor + 2 H+ → monodehydroascorbate radical + a reduced electron acceptor ,
7,8-dihydroneopterin ↔ 7,8-dihydromonapterin ,
2 S-sulfanylglutathione + 2 H+ ↔ bisorganyltrisulfane + hydrogen sulfide ,
4-(2-aminophenyl)-2,4-dioxobutanoate → kynurenate + H2O + H+ ,
α-D-glucose 1-phosphate ↔ β-D-glucose 1-phosphate ,
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
(S)-4,5-dihydroxypentan-2,3-dione → (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
(S)-4,5-dihydroxypentan-2,3-dione → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate ,
(S)-1-pyrroline-5-carboxylate + NAD+ + 2 H2O → L-glutamate + NADH + H+ ,
putrescine + 2-oxoglutarate → 4-aminobutanal + L-glutamate ,
L-glutamate + ATP + NADPH + H+ → ADP + L-glutamate-5-semialdehyde + NADP+ + phosphate ,
(S)-lactate + an oxidized electron acceptor → pyruvate + a reduced electron acceptor ,
histidinol + NAD+ → histidinal + NADH + H+ ,
histidinal + NAD+ + H2O → L-histidine + NADH + 2 H+ ,
XMP + ammonium + ATP → GMP + AMP + diphosphate + 2 H+ ,
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH ,
formate + H+ → CO2 + H2 ,
3 2,3-dihydroxybenzoyl-AMP + 3 L-seryl-AMP = enterobactin + 6 AMP + 6 H+ ,
ATP + L-serine ↔ L-seryl-AMP + diphosphate ,
D-ribulose + ATP → D-ribulose 1-phosphate + ADP + H+ ,
D-ribulose 1-phosphate ↔ glycolaldehyde + dihydroxyacetone phosphate ,
cis-aconitate + H2O ↔ D-threo-isocitrate ,
citrate ↔ cis-aconitate + H2O ,
ATP + an aliphatic sulfonate[periplasmic space] + H2O → an aliphatic sulfonate[cytosol] + ADP + phosphate + H+ ,
(2S)-2-isopropylmalate ↔ 2-isopropylmaleate + H2O ,
(2R,3S)-3-isopropylmalate + NAD+ ↔ (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ ,
2-oxoglutarate + coenzyme A + NAD+ → succinyl-CoA + CO2 + NADH ,
4-phospho-hydroxy-L-threonine + NAD+(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+ ,
protoheme IX + 2 H+ → protoporphyrin IX + Fe2+


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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