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Escherichia coli K-12 substr. MG1655 Reactions Class: Small-Molecule Reactions

Summary:
Reactions in which all participants are small molecules.

Parent Classes:
Reactions Classified By Substrate

Instances:
1.1.1.1: ethanol + NAD+ ↔ acetaldehyde + NADH + H+ ,
1.1.1.1: a primary alcohol + NAD+ ↔ an aldehyde + NADH + H+ ,
1.1.1.2: an alcohol + NADP+ = an aldehyde + NADPH + H+ ,
1.1.1.3: L-homoserine + NAD(P)+ ← L-aspartate-semialdehyde + NAD(P)H + H+ ,
1.1.1.6: glycerol + NAD+ ↔ dihydroxyacetone + NADH + H+ ,
1.1.1.17: D-mannitol 1-phosphate + NAD+ ↔ β-D-fructofuranose 6-phosphate + NADH + H+ ,
1.1.1.22: UDP-α-D-glucose + 2 NAD+ + H2O → UDP-α-D-glucuronate + 2 NADH + 3 H+ ,
1.1.1.25: shikimate + NADP+ ↔ 3-dehydroshikimate + NADPH + H+ ,
1.1.1.28: (R)-lactate + NAD+ ← pyruvate + NADH + H+ ,
1.1.1.35: 3-hydroxyadipyl-CoA + NAD+ ↔ 3-oxoadipyl-CoA + NADH + H+ ,
1.1.1.35: a (3S)-3-hydroxyacyl-CoA + NAD+ → a 3-oxoacyl-CoA + NADH + H+ ,
1.1.1.37: (S)-malate + NAD+ ↔ oxaloacetate + NADH + H+ ,
1.1.1.38/4.1.1.3: oxaloacetate + H+ → pyruvate + CO2 ,
1.1.1.38/1.1.1.39: (S)-malate + NAD+ → CO2 + pyruvate + NADH ,
1.1.1.40: (S)-malate + NADP+ → CO2 + pyruvate + NADPH ,
1.1.1.42: D-threo-isocitrate + NADP+ → 2-oxoglutarate + CO2 + NADPH ,
1.1.1.44: D-gluconate 6-phosphate + NADP+ → D-ribulose 5-phosphate + CO2 + NADPH ,
1.1.1.49: β-D-glucose 6-phosphate + NADP+ → 6-phospho D-glucono-1,5-lactone + NADPH + H+ ,
1.1.1.57: D-mannonate + NAD+ ↔ D-fructuronate + NADH + H+ ,
1.1.1.58: D-altronate + NAD+ ↔ D-tagaturonate + NADH + H+ ,
1.1.1.60: D-glycerate + NAD(P)+ ← tartronate semialdehyde + NAD(P)H + H+ ,
1.1.1.61: 4-hydroxybutanoate + NAD+ ↔ succinate semialdehyde + NADH + H+ ,
1.1.1.69: D-gluconate + NAD(P)+ ↔ 5-dehydro-D-gluconate + NAD(P)H + H+ ,
1.1.1.75: (R)-1-aminopropan-2-ol + NAD+ ← aminoacetone + NADH + H+ ,
1.1.1.77: (S)-propane-1,2-diol + NAD+ ↔ (S)-lactaldehyde + NADH + H+ ,
1.1.1.77: ethylene glycol + NAD+ ↔ glycolaldehyde + NADH + H+ ,
1.1.1.79: glycolate + NADP+ ← glyoxylate + NADPH + H+ ,
1.1.1.83: (R)-malate + NAD+ → CO2 + pyruvate + NADH ,
1.1.1.86: (R)-2,3-dihydroxy-3-methylpentanoate + NADP+ ← (S)-2-aceto-2-hydroxybutanoate + NADPH + H+ ,
1.1.1.86: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP+ ↔ (S)-2-acetolactate + NADPH + H+ ,
1.1.1.91: 4-nitrobenzyl alcohol + NADP+ = 4-nitrobenzaldehyde + NADPH + H+ ,
1.1.1.93: L-tartrate + NAD+ = 2-hydroxy-3-oxosuccinate + NADH + H+ ,
1.1.1.94: sn-glycerol 3-phosphate + NAD(P)+ ← glycerone phosphate + NAD(P)H + H+ ,
1.1.1.95: 3-phospho-D-glycerate + NAD+ ↔ 3-phospho-hydroxypyruvate + NADH + H+ ,
1.1.1.103: L-threonine + NAD+ → 2-amino-3-oxobutanoate + NADH + H+ ,
1.1.1.125: 2-deoxygluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+ ,
1.1.1.127: 2-dehydro-3-deoxy-D-gluconate + NAD+ = 3-deoxy-D-glycero-2,5-hexodiulosonate + NADH + H+ ,
1.1.1.130: 3-keto-L-gulonate + NAD+ ← 2,3-dioxo-L-gulonate + NADH + H+ ,
1.1.1.133: dTDP-β-L-rhamnose + NADP+ ← dTDP-4-dehydro-β-L-rhamnose + NADPH + H+ ,
1.1.1.140: D-sorbitol 6-phosphate + NAD+ ↔ D-fructose 6-phosphate + NADH + H+ ,
1.1.1.154: S-ureidoglycolate + NAD(P)+ → oxalurate + NAD(P)H + H+ ,
1.1.1.159: cholate + NAD+ = 3α,12α-dihydroxy-7-oxo-5β-cholan-24-oate + NADH + H+ ,
1.1.1.169: (R)-pantoate + NADP+ ← 2-dehydropantoate + NADPH + H+ ,
1.1.1.193: 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP+ ← 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ ,
1.1.1.205: IMP + NAD+ + H2O → XMP + NADH + H+ ,
1.1.1.211: 3-hydroxy-5-cis-tetradecenoyl-CoA + NAD+ = 3-keto-5-cis-tetradecenoyl-CoA + NADH + H+ ,
1.1.1.215: D-gluconate + NADP+ ← 2-keto-D-gluconate + NADPH + H+ ,
1.1.1.264: L-idonate + NAD(P)+ ↔ 5-dehydro-D-gluconate + NAD(P)H + H+ ,
1.1.1.267: 2-C-methyl-D-erythritol 4-phosphate + NADP+ ↔ 1-deoxy-D-xylulose 5-phosphate + NADPH + H+ ,
1.1.1.271: GDP-β-L-fucose + NADP+ ← GDP-4-dehydro-6-deoxy-α-D-mannose + NADPH + H+ ,
1.1.1.274: 2-keto-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.282: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+ ,
1.1.1.282: shikimate + NAD(P)+ ← 3-dehydroshikimate + NAD(P)H + H+ ,
1.1.1.283: (S)-lactaldehyde + NADP+ ← methylglyoxal + NADPH + H+ ,
1.1.1.284: S-hydroxymethylglutathione + NAD(P)+S-formylglutathione + NAD(P)H + H+ ,
1.1.1.290: erythronate-4-phosphate + NAD+ → 2-oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ ,
1.1.1.298: 3-hydroxypropanoate + NADP+ ← 3-oxopropanoate + NADPH + H+ ,
1.1.1.305: UDP-α-D-glucuronate + NAD+ → UDP-β-L-threo-pentapyranos-4-ulose + CO2 + NADH ,
1.1.1.336: UDP-N-acetyl-α-D-mannosamine + 2 NAD+ + H2O → UDP-N-acetyl-α-D-mannosaminuronate + 2 NADH + 3 H+ ,
1.1.1.346: 2-keto-L-gulonate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.350: S-ureidoglycolate + NAD+ → oxalurate + NADH + H+ ,
1.1.1.358: (R)-pantolactone + NADP+ ↔ 2-dehydropantolactone + NADPH + H+ ,
1.1.1.373: 2,3-dihydroxypropane 1-sulfonate + NAD+ ← sulfolactaldehyde + NADH + H+ ,
1.1.1.381: L-allo-threonine + NADP+ = aminoacetone + CO2 + NADPH ,
1.1.1.-: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP+ = ethyl-2-methylacetoacetate + NADPH + H+ ,
1.1.1.-: 1,3-propanediol + NADP+ = 3-hydroxypropionaldehyde + NADPH + H+ ,
1.1.1.-: (R)-propane-1,2-diol + NADP+ = (R)-lactaldehyde + NADPH + H+ ,
1.1.1.-: acetol + NADP+ ↔ methylglyoxal + NADPH + H+ ,
1.1.1.-: isobutanol + NADP+ = isobutanal + NADPH + H+ ,
1.1.1.-: galactitol 1-phosphate + NAD+ ↔ D-tagatofuranose 6-phosphate + NADH + H+ ,
1.1.1.-: 2,5-didehydro-D-gluconate + NAD(P)H + H+ = 2-keto-L-gulonate + NAD(P)+ ,
1.1.1.-: 2-keto-L-gulonate + NADPH + H+ → L-idonate + NADP+ ,
1.1.1.-: 2-keto-D-gluconate + NADPH + H+ = L-idonate + NADP+ ,
1.1.1.-: (R)-2-hydroxyglutarate + NAD+ ↔ 2-oxoglutarate + NADH + H+ ,
1.1.1.-: 11-deoxycorticosterone + NADH + H+ = 4-pregnen-20,21-diol-3-one + NAD+ ,
1.1.1.-: 2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: 5-dehydro-D-gluconate + NADP+ ← 2,5-didehydro-D-gluconate + NADPH + H+ ,
1.1.1.-: sn-glycerol 3-phosphate + NADP+ ← L-glyceraldehyde 3-phosphate + NADPH + H+ ,
1.1.1.-: (S)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+ ,
1.1.1.-: methylglyoxal + NADH + H+ = acetol + NAD+ ,
1.1.1.-: D-glycerate + NAD+ ↔ tartronate semialdehyde + NADH + H+ ,
1.1.1.-: (S)-propane-1,2-diol + NADP+ = (S)-lactaldehyde + NADPH + H+ ,
1.1.1.-: acetoin + NADP+ = diacetyl + NADPH + H+ ,
1.1.1.-: D-glycerate + NADP+ ← hydroxypyruvate + NADPH + H+ ,
1.1.1.-: dTDP-β-L-rhamnose + NAD+ ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + NADH + H+ ,
1.1.3.-: (S)-2-hydroxyglutarate + oxygen → 2-oxoglutarate + hydrogen peroxide ,
1.1.5.2: D-glucopyranose[periplasmic space] + a ubiquinone[inner membrane] → D-glucono-1,5-lactone[periplasmic space] + an ubiquinol[inner membrane] ,
1.1.5.2: β-D-glucopyranose[periplasmic space] + a ubiquinone[inner membrane] → D-glucono-1,5-lactone[periplasmic space] + an ubiquinol[inner membrane] ,
1.1.5.3: sn-glycerol 3-phosphate + a ubiquinone[inner membrane] → glycerone phosphate + an ubiquinol[inner membrane] ,
1.1.5.3: sn-glycerol 3-phosphate + a menaquinone[inner membrane] → glycerone phosphate + a menaquinol[inner membrane] ,
1.1.5.4: (S)-malate + an electron-transfer quinone[inner membrane] → oxaloacetate + an electron-transfer quinol[inner membrane] ,
1.1.5.6: formate[periplasmic space] + a menaquinone[inner membrane] + 2 H+ → CO2[periplasmic space] + a menaquinol[inner membrane] + H+[periplasmic space] ,
1.1.5.-: an aldose[periplasmic space] + an oxidized unknown electron acceptor[periplasmic space] + H2O[periplasmic space] = an aldonate[periplasmic space] + an reduced unknown electron acceptor[periplasmic space] + H+[periplasmic space] ,
1.1.5.-: (R)-lactate + a ubiquinone[inner membrane] → pyruvate + an ubiquinol[inner membrane] ,
1.1.99.1: choline + an oxidized unknown electron acceptor → betaine aldehyde + an reduced unknown electron acceptor ,
1.1.99.14: glycolate + an oxidized unknown electron acceptor → glyoxylate + an reduced unknown electron acceptor ,
1.1.99.33: formate + an oxidized unknown electron acceptor + H+ → CO2 + an reduced unknown electron acceptor ,
1.2.1.4: acetaldehyde + NADP+ + H2O → acetate + NADPH + 2 H+ ,
1.2.1.4: an aldehyde + NADP+ + H2O → a carboxylate + NADPH + 2 H+ ,
1.2.1.8: betaine aldehyde + NAD+ + H2O → glycine betaine + NADH + 2 H+ ,
1.2.1.10: acetaldehyde + coenzyme A + NAD+ ↔ acetyl-CoA + NADH + H+ ,
1.2.1.11: L-aspartate-semialdehyde + NADP+ + phosphate ↔ L-aspartyl-4-phosphate + NADPH + H+ ,
1.2.1.12: D-glyceraldehyde 3-phosphate + NAD+ + phosphate ↔ 1,3-bisphospho-D-glycerate + NADH + H+ ,
1.2.1.19: 4-aminobutanal + NAD+ + H2O → 4-aminobutanoate + NADH + 2 H+ ,
1.2.1.21: glycolaldehyde + NAD+ + H2O → glycolate + NADH + 2 H+ ,
1.2.1.22: (S)-lactaldehyde + NAD+ + H2O → (S)-lactate + NADH + 2 H+ ,
1.2.1.24: succinate semialdehyde + NAD+ + H2O → succinate + NADH + 2 H+ ,
1.2.1.38: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate ↔ N-acetylglutamyl-phosphate + NADPH + H+ ,
1.2.1.39: phenylacetaldehyde + NAD+ + H2O ↔ phenylacetate + NADH + 2 H+ ,
1.2.1.41: L-glutamate-5-semialdehyde + NADP+ + phosphate ← γ-L-glutamyl 5-phosphate + NADPH + H+ ,
1.2.1.71: N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O → N2-succinylglutamate + NADH + 2 H+ ,
1.2.1.72: D-erythrose 4-phosphate + NAD+ + H2O → erythronate-4-phosphate + NADH + 2 H+ ,
1.2.1.79: succinate semialdehyde + NADP+ + H2O → succinate + NADPH + 2 H+ ,
1.2.1.88: L-glutamate-5-semialdehyde + NAD+ + H2O → L-glutamate + NADH + 2 H+ ,
1.2.1.91: 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde + NADP+ + H2O → 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H+ ,
1.2.1.-: 3-hydroxypropionaldehyde + NAD+ + H2O → 3-hydroxypropanoate + NADH + 2 H+ ,
1.2.1.-: 4-(γ-glutamylamino)butanal + NAD(P)+ + H2O → 4-(γ-L-glutamylamino)butanoate + NAD(P)H + 2 H+ ,
1.2.1.-: pyruvate + coenzyme A + NAD+ → acetyl-CoA + CO2 + NADH ,
1.2.4.1: pyruvate + lipoamide + H+ = S-acetyldihydrolipoamide + CO2 ,
1.2.5.1: pyruvate + a ubiquinone[inner membrane] + H2O → CO2 + acetate + an ubiquinol[inner membrane] ,
1.2.99.7: an aldehyde[periplasmic space] + FAD[periplasmic space] + H2O[periplasmic space] = a carboxylate[periplasmic space] + FADH2[periplasmic space] ,
1.3.1.1: 5,6-dihydrouracil + NAD+ ↔ uracil + NADH + H+ ,
1.3.1.1: 5,6-dihydrothymine + NAD+ ↔ thymine + NADH + H+ ,
1.3.1.12: prephenate + NAD+ → 4-hydroxyphenylpyruvate + CO2 + NADH ,
1.3.1.28: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD+ → 2,3-dihydroxybenzoate + NADH + H+ ,
1.3.1.34: trans-dec-2-enoyl-CoA + NADP+ ← trans-Δ2, cis-Δ4-decadienoyl-CoA + NADPH + H+ ,
1.3.1.38: a 2,3,4-saturated fatty acyl CoA + NADP+ ← a trans-2-enoyl-CoA + NADPH + H+ ,
1.3.1.76: precorrin-2 + NAD+ ↔ sirohydrochlorin + NADH + 2 H+ ,
1.3.1.84: propanoyl-CoA + NADP+ = acryloyl-CoA + NADPH + H+ ,
1.3.1.87: (2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ → 2,3-dihydroxy-trans-cinnamate + NADH + H+ ,
1.3.1.87: 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ → 3-(2,3-dihydroxyphenyl)propanoate + NADH + H+ ,
1.3.1.98: UDP-N-acetyl-α-D-muramate + NADP+ ← UDP-N-acetyl-α-D-glucosamine-enolpyruvate + NADPH + H+ ,
1.3.1.-: N-ethylmaleimide + NADPH + H+ → N-ethylsuccinimide + NADP+ ,
1.3.3.3: coproporphyrinogen III + oxygen + 2 H+ → protoporphyrinogen IX + 2 CO2 + 2 H2O ,
1.3.3.4: protoporphyrinogen IX + 3 oxygen → protoporphyrin IX + 3 hydrogen peroxide ,
1.3.5.1: succinate + a ubiquinone[inner membrane] → fumarate + an ubiquinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + a menaquinone[inner membrane] → orotate + a menaquinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + a ubiquinone[inner membrane] → orotate + an ubiquinol[inner membrane] ,
1.3.5.2: (S)-dihydroorotate + an electron-transfer quinone[inner membrane] → orotate + an electron-transfer quinol[inner membrane] ,
1.3.5.3: protoporphyrin IX + 3 a menaquinol[inner membrane] ← protoporphyrinogen IX + 3 a menaquinone[inner membrane] ,
1.3.5.4: fumarate + a menaquinol[inner membrane] ↔ succinate + a menaquinone[inner membrane] ,
1.3.8.4: isovaleryl-CoA + an oxidized electron-transfer flavoprotein + H+ = 3-methylcrotonyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.8.-: a 2,3,4-saturated fatty acyl CoA + an oxidized electron-transfer flavoprotein + H+ → a trans-2-enoyl-CoA + a reduced electron-transfer flavoprotein ,
1.3.99.22: coproporphyrinogen III + 2 S-adenosyl-L-methionine → protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine ,
1.3.99.-: γ-butyrobetainyl-CoA + an oxidized unknown electron acceptor ← crotonobetainyl-CoA + an reduced unknown electron acceptor ,
1.4.1.4: L-glutamate + NADP+ + H2O ↔ ammonium + 2-oxoglutarate + NADPH + H+ ,
1.4.1.13: 2 L-glutamate + NADP+ ← L-glutamine + 2-oxoglutarate + NADPH + H+ ,
1.4.3.5: pyridoxine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.5: pyridoxamine 5'-phosphate + oxygen + H2O → ammonium + hydrogen peroxide + pyridoxal 5'-phosphate ,
1.4.3.16: L-aspartate + oxygen → hydrogen peroxide + 2-iminosuccinate + H+ ,
1.4.3.21: aminoacetone[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → methylglyoxal[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: an aliphatic amine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → an aldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: a primary amine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → an aldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.3.21: 2-phenylethylamine[periplasmic space] + H2O[periplasmic space] + oxygen[periplasmic space] → phenylacetaldehyde[periplasmic space] + ammonium[periplasmic space] + hydrogen peroxide[periplasmic space] ,
1.4.5.1: a D-amino acid + an electron-transfer quinone[inner membrane] + H2O → ammonium + a 2-oxo carboxylate + an electron-transfer quinol[inner membrane] ,
1.4.5.-: D-alanine + an electron-transfer quinone[inner membrane] + H2O → ammonium + pyruvate + an electron-transfer quinol[inner membrane] ,
1.5.1.2: L-proline + NAD(P)+ ← (S)-1-pyrroline-5-carboxylate + NAD(P)H + 2 H+ ,
1.5.1.3: a tetrahydrofolate + NADP+ ← a 7,8-dihydrofolate + NADPH + H+ ,
1.5.1.5: a 5,10-methylene-tetrahydrofolate + NADP+ ↔ a 5,10-methenyltetrahydrofolate + NADPH ,
1.5.1.20: an N5-methyl-tetrahydrofolate + NAD+ ← a 5,10-methylene-tetrahydrofolate + NADH + H+ ,
1.5.1.30: reduced riboflavin + NADP+ ← riboflavin + NADPH + 2 H+ ,
1.5.1.34: a 5,6,7,8-tetrahydropteridine + NAD(P)+ = a 6,7-dihydropteridine + NAD(P)H + H+ ,
1.5.1.37: NAD+ + FADH2 = NADH + FAD + 2 H+ ,
1.5.1.38: NADP+ + FMNH2 ← NADPH + FMN + 2 H+ ,
1.5.1.39: FMNH2 + NAD(P)+ = FMN + NAD(P)H + 2 H+ ,
1.5.1.41: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+ ,
1.5.1.-: 5,6,7,8-tetrahydromonapterin + NADP+ ← 7,8-dihydromonapterin + NADPH + H+ ,
1.5.3.2: N-methyl-L-tryptophan + oxygen + H2O → L-tryptophan + hydrogen peroxide + formaldehyde ,
1.5.5.2: L-proline + a ubiquinone[inner membrane] → (S)-1-pyrroline-5-carboxylate + an ubiquinol[inner membrane] + H+ ,
1.5.99.-: L-aspartate + fumarate → 2-iminosuccinate + succinate + H+ ,
1.6.1.2: NADH + NADP+ + H+[periplasmic space] → NADPH + NAD+ + H+[cytosol] ,
1.6.1.2/1.6.1.3: NADPH + NAD+ ↔ NADH + NADP+ ,
1.6.5.2: an electron-transfer quinone[inner membrane] + NAD(P)H + H+ → an electron-transfer quinol[inner membrane] + NAD(P)+ ,
1.6.5.3: NADH + a ubiquinone[inner membrane] + 5 H+ ↔ NAD+ + an ubiquinol[inner membrane] + 4 H+[periplasmic space] ,
1.6.5.5: 2 a quinone + NADPH + H+ ↔ 2 a semiquinone + NADP+ ,
1.6.5.9: NADH + a ubiquinone[inner membrane] + H+ → NAD+ + an ubiquinol[inner membrane] ,
1.6.5.10: NADPH + an electron-transfer quinone[inner membrane] + H+ → NADP+ + an electron-transfer quinol[inner membrane] ,
1.6.5.11: menadione + NADH + H+ = menadiol + NAD+ ,
1.6.5.-: methyl-1,4-benzoquinone + 2 NADPH + 2 H+ = methyl-1,4-benzoquinol + 2 NADP+ ,
1.6.5.-: 2 a quinone + NADH + H+ = 2 a semiquinone + NAD+ ,
1.6.5.-: NADH + a menaquinone[inner membrane] + 5 H+ → NAD+ + a menaquinol[inner membrane] + 4 H+[periplasmic space] ,
1.6.6.9: trimethylamine N-oxide + NADH + 2 H+ → trimethylamine + NAD+ + H2O ,
1.7.1.7: ammonium + IMP + NADP+ ← GMP + NADPH + 2 H+ ,
1.7.1.13: preQ1 + 2 NADP+ ← preQ0 + 2 NADPH + 3 H+ ,
1.7.1.15: ammonium + 3 NAD+ + 2 H2O ← nitrite + 3 NADH + 5 H+ ,
1.7.1.-: an oxidized nitroaromatic compound + NAD(P)H → a reduced nitroaromatic compound + NAD(P)+ ,
1.7.1.-: methyl red + 2 NADH + 2 H+ = anthranilate + N,N'-dimethyl-p-phenylenediamine + 2 NAD+ ,
1.7.2.2: nitrite[periplasmic space] + 3 a menaquinol[inner membrane] + 2 H+[periplasmic space] → ammonium[periplasmic space] + 3 a menaquinone[inner membrane] + 2 H2O[periplasmic space] ,
1.7.2.3: trimethylamine N-oxide[periplasmic space] + a menaquinol[inner membrane] + H+[periplasmic space] → trimethylamine[periplasmic space] + a menaquinone[inner membrane] + H2O[periplasmic space] ,
1.7.5.1: nitrate + an ubiquinol[inner membrane] + 2 H+ → nitrite + a ubiquinone[inner membrane] + 2 H+[periplasmic space] + H2O ,
1.7.5.1: nitrate + a menaquinol[inner membrane] + 2 H+ → nitrite + a menaquinone[inner membrane] + H2O + 2 H+[periplasmic space] ,
1.7.99.1: ammonium + an oxidized unknown electron acceptor + H2O ← hydroxylamine + an reduced unknown electron acceptor + H+ ,
1.7.99.4: nitrate[periplasmic space] + an ubiquinol[inner membrane] → nitrite[periplasmic space] + a ubiquinone[inner membrane] + H2O[periplasmic space] ,
1.7.99.4: nitrate[periplasmic space] + a menaquinol[inner membrane] → nitrite[periplasmic space] + a menaquinone[inner membrane] + H2O[periplasmic space] ,
1.8.1.2: hydrogen sulfide + 3 NADP+ + 3 H2O ← sulfite + 3 NADPH + 5 H+ ,
1.8.1.7: 2 glutathione + NADP+ ← glutathione disulfide + NADPH + H+ ,
1.8.1.-: an organic hydroperoxide + NADH + H+ → an alcohol + NAD+ + H2O ,
1.8.4.4: D-cystine + 2 glutathione = glutathione disulfide + 2 D-cysteine ,
1.8.4.4: L-cystine + 2 glutathione = glutathione disulfide + 2 L-cysteine ,
1.8.5.3: dimethyl sulfide[periplasmic space] + a menaquinone[inner membrane] + H2O[periplasmic space] ← dimethyl sulfoxide[periplasmic space] + a menaquinol[inner membrane] ,
1.10.3.10: 2 an ubiquinol[inner membrane] + 8 H+ + oxygen → 2 a ubiquinone[inner membrane] + 2 H2O + 8 H+[periplasmic space] ,
1.10.3.14: 2 an ubiquinol[inner membrane] + oxygen + 4 H+ → 2 a ubiquinone[inner membrane] + 2 H2O + 4 H+[periplasmic space] ,
1.11.1.7: 2 a phenolic donor + hydrogen peroxide = 2 a phenoxyl radical of a phenolic donor + 2 H2O ,
1.11.1.9: hydrogen peroxide + 2 glutathione → glutathione disulfide + 2 H2O ,
1.11.1.11: 2 L-ascorbate + hydrogen peroxide + H+ → L-ascorbate + L-dehydro-ascorbate + 2 H2O ,
1.11.1.21: hydrogen peroxide + an reduced unknown electron acceptor → an oxidized unknown electron acceptor + 2 H2O ,
1.11.1.21: 2 hydrogen peroxide → 2 H2O + oxygen ,
1.12.99.6: a menaquinone[inner membrane] + 2 H+ + H2[periplasmic space] → a menaquinol[inner membrane] + 2 H+[periplasmic space] ,
1.12.99.6: 2 H2 + oxygen → 2 H2O ,
1.13.11.16: 3-(2,3-dihydroxyphenyl)propanoate + oxygen → (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H+ ,
1.13.11.16: 2,3-dihydroxy-trans-cinnamate + oxygen → (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H+ ,
1.13.11.24: quercetin + oxygen → 2-protocatechuoylphloroglucinolcarboxylate + carbon monoxide ,
1.14.11.17: taurine + 2-oxoglutarate + oxygen → 2-aminoacetaldehyde + sulfite + succinate + CO2 + H+ ,
1.14.11.33: 1-ethyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + acetaldehyde + succinate ,
1.14.11.33: N1-methyladenine + 2-oxoglutarate + oxygen → adenine + CO2 + formaldehyde + succinate ,
1.14.11.33: N3-methylcytosine + 2-oxoglutarate + oxygen → cytosine + CO2 + formaldehyde + succinate + H+ ,
1.14.11.33: a methylated nucleobase within DNA + 2-oxoglutarate + oxygen → a nucleobase within DNA + CO2 + formaldehyde + succinate ,
1.14.11.47: a [50S ribosomal subunit protein L16]-L-arginine81 + 2-oxoglutarate + oxygen → a [50S ribosomal subunit protein L16]-(3R)-3-hydroxy-L-arginine81 + succinate + CO2 ,
1.14.12.17: 2 nitric oxide + NAD(P)H + 2 oxygen → 2 nitrate + NAD(P)+ + H+ ,
1.14.12.19: 3-phenylpropanoate + NADH + oxygen + H+ → 3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD+ ,
1.14.12.19: trans-cinnamate + NADH + oxygen + H+ → (2E)-3-(5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD+ ,
1.14.13.127: 3-(3-hydroxyphenyl)propanoate + NADH + H+ + oxygen → 3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O ,
1.14.13.127: 3-hydroxy-trans-cinnamate + NADH + oxygen + H+ → 2,3-dihydroxy-trans-cinnamate + NAD+ + H2O ,
1.14.13.149: phenylacetyl-CoA + NADPH + oxygen + H+ → 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O ,
1.14.13.-: 2-methoxy-6-(all-trans-octaprenyl)phenol + NADPH + oxygen + H+ → 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + NADP+ + H2O ,
1.14.13.-: 2-octaprenylphenol + NADPH + oxygen + H+ → 3-(all-trans-octaprenyl)benzene-1,2-diol + NADP+ + H2O ,
1.14.13.-: a [protein chain elongation factor EF-P]-L-lysine34 + NADPH + oxygen + H+ → a [protein chain elongation factor EF-P]-5-hydroxy-L-lysine34 + NADP+ + H2O ,
1.14.14.5: 1-butanesulfonate + FMNH2 + oxygen → butanal + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: 3-(N-morpholino)propanesulfonate + FMNH2 + oxygen → 3-(N-morpholino)propanal + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: an alkylsulfonate + FMNH2 + oxygen → an aldehyde + sulfite + FMN + H2O + 2 H+ ,
1.14.14.5: isethionate + FMNH2 + oxygen → glycolaldehyde + sulfite + FMN + H2O + 2 H+ ,
1.14.99.46: uracil + FMNH2 + oxygen → (Z)-3-ureidoacrylate peracid + FMN + H+ ,
1.14.99.46: thymine + FMNH2 + oxygen → (Z)-2-methylureidoacrylate peracid + FMN + H+ ,
1.14.-.-: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + an reduced unknown electron acceptor + oxygen → 3-demethylubiquinol-8 + an oxidized unknown electron acceptor + H2O ,
1.15.1.1: 2 superoxide + 2 H+ → hydrogen peroxide + oxygen ,
1.16.1.9: 2 Fe2+ + 2 a siderophore + NADP+ + H+ ← 2 an Fe(III)-siderophore + NADPH ,
1.16.1.9: 2 Fe2+ + 2 (2,3-dihydroxybenzoylserine)3 + NADP+ ← 2 ferric (2,3-dihydroxybenzoylserine)3 + NADPH + 9 H+ ,
1.16.1.-: Cu2+ + NADH = Cu+ + NAD+ ,
1.16.3.1: 4 Fe2+ + 4 H+ + oxygen → 4 Fe3+ + 2 H2O ,
1.16.3.2: 4 Fe2+ + oxygen + 6 H2O → 4 [FeO(OH)] monomer + 8 H+ ,
1.16.3.-: 2 Cu+[periplasmic space] + 2 H+[periplasmic space] + oxygen[periplasmic space] → 2 Cu2+[periplasmic space] + 2 H2O[periplasmic space] ,
1.17.1.2: isopentenyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.2: dimethylallyl diphosphate + NAD(P)+ + H2O ← 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + NAD(P)H + H+ ,
1.17.1.4: hypoxanthine + NAD+ + H2O → xanthine + NADH + H+ ,
1.17.1.4: xanthine + NAD+ + H2O → urate + NADH + H+ ,
1.17.1.8: (S)-2,3,4,5-tetrahydrodipicolinate + NADP+ + H2O ← (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ ,
1.17.7.3: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate + an oxidized flavodoxin + H2O + H+ ← 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + a reduced flavodoxin ,
1.97.1.9: selenite + an oxidized unknown electron acceptor + H2O ← selenate + an reduced unknown electron acceptor ,
1.97.1.-: S-adenosyl-L-methionine + an inactive ribonucleoside triphosphate reductase ↔ 5'-deoxyadenosine + an active ribonucleoside triphosphate reductase + L-methionine ,
1.97.1.-: tellurite + an reduced unknown electron acceptor → Te0 + an oxidized unknown electron acceptor ,
1.-.-.-: d-biotin d-sulfoxide + a reduced thioredoxin = biotin + an oxidized thioredoxin + H2O ,
1.-.-.-: an oxidized nitroaromatic compound + NADPH = a reduced nitroaromatic compound + NADP+ ,
2.1.1.10: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+ ,
2.1.1.13: L-homocysteine + an N5-methyl-tetrahydrofolate → L-methionine + a tetrahydrofolate ,
2.1.1.14: L-homocysteine + N5-methyl--tetrahydropteroyl tri-L-glutamate → L-methionine + tetrahydropteroyl tri-L-glutamate ,
2.1.1.45: a 5,10-methylene-tetrahydrofolate + dUMP → dTMP + a 7,8-dihydrofolate ,
2.1.1.64: S-adenosyl-L-methionine + 3-demethylubiquinol-8S-adenosyl-L-homocysteine + ubiquinol-8 + H+ ,
2.1.1.77: S-adenosyl-L-methionine + a [protein]-L-β-isoaspartate → S-adenosyl-L-homocysteine + a protein L-β-isoaspartate α-methyl ester ,
2.1.1.79: a [phospholipid] olefinic fatty acid + S-adenosyl-L-methionine → a [phospholipid] cyclopropane fatty acid + S-adenosyl-L-homocysteine + H+ ,
2.1.1.144: trans-aconitate + S-adenosyl-L-methionine → (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine ,
2.1.1.163: S-adenosyl-L-methionine + demethylmenaquinol-8 → S-adenosyl-L-homocysteine + menaquinol-8 + H+ ,
2.1.1.197: a malonyl-[acp] + S-adenosyl-L-methionine → a malonyl-[acp] methyl ester + S-adenosyl-L-homocysteine ,
2.1.1.201: 2-methoxy-6-all trans-octaprenyl-2-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine → 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.222: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine → 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H+ ,
2.1.1.242: a guanine1516 in 16S rRNA + S-adenosyl-L-methionine → an N2-methylguanine1516 in 16S rRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.264: guanine2069 in 23S rRNA + S-adenosyl-L-methionine → N7-methylguanine2069 in 23S rRNA + S-adenosyl-L-homocysteine ,
2.1.1.265: tellurite + S-adenosyl-L-methionine → methanetelluronate + S-adenosyl-L-homocysteine ,
2.1.1.266: adenine2030 in 23S rRNA + S-adenosyl-L-methionine → N6-methyladenine2030 in 23S rRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.1.297: a [release factor]-L-glutamine + S-adenosyl-L-methionine → a [release factor]-N5-methyl-L-glutamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.298: a [ribosomal protein L3]-L-glutamine + S-adenosyl-L-methionine → a [ribosomal protein L3]-N5-methyl-L-glutamine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: L-homocysteine + S-adenosyl-L-methionine → L-methionine + S-adenosyl-L-homocysteine + H+ ,
2.1.1.-: S-adenosyl-L-methionine + a demethylated methyl donor → S-adenosyl-L-homocysteine + a methylated methyl donor + H+ ,
2.1.1.-: N6-L-threonylcarbamoyladenine37 in tRNA + S-adenosyl-L-methionine → N6-methyl-threonylcarbamoyladenosine 37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
2.1.2.1: L-serine + a tetrahydrofolate ↔ glycine + a 5,10-methylene-tetrahydrofolate + H2O ,
2.1.2.2: an N10-formyl-tetrahydrofolate + N1-(5-phospho-β-D-ribosyl)glycinamide ↔ a tetrahydrofolate + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + H+ ,
2.1.2.3: an N10-formyl-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ↔ a tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
2.1.2.11: a 5,10-methylene-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O ↔ 2-dehydropantoate + a tetrahydrofolate ,
2.1.2.13: UDP-4-amino-4-deoxy-β-L-arabinopyranose + an N10-formyl-tetrahydrofolate → UDP-4-deoxy-4-formamido-β-L-arabinopyranose + a tetrahydrofolate + H+ ,
2.1.2.-: N1-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + ADP + phosphate + H+ ,
2.1.3.2: L-aspartate + carbamoyl-phosphate → N-carbamoyl-L-aspartate + phosphate + H+ ,
2.1.3.3: L-ornithine + carbamoyl-phosphate ↔ L-citrulline + phosphate + H+ ,
2.1.3.5: oxamate + carbamoyl-phosphate ← oxalurate + phosphate ,
2.2.1.1: D-erythrose 4-phosphate + D-xylulose 5-phosphate ↔ β-D-fructofuranose 6-phosphate + D-glyceraldehyde 3-phosphate ,
2.2.1.1: D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate ↔ D-ribose 5-phosphate + D-xylulose 5-phosphate ,
2.2.1.2: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate ↔ β-D-fructofuranose 6-phosphate + D-erythrose 4-phosphate ,
2.2.1.6: pyruvate + 2-oxobutanoate + H+ → (S)-2-aceto-2-hydroxybutanoate + CO2 ,
2.2.1.6: 2 pyruvate + H+ ↔ (S)-2-acetolactate + CO2 ,
2.2.1.7: pyruvate + D-glyceraldehyde 3-phosphate + H+ → CO2 + 1-deoxy-D-xylulose 5-phosphate ,
2.2.1.9: isochorismate + 2-oxoglutarate + H+ → 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2 ,
2.3.1.1: L-methionine + acetyl-CoA = N-α-acetyl-L-methionine + coenzyme A + H+ ,
2.3.1.1: L-glutamate + acetyl-CoA ↔ N-acetyl-L-glutamate + coenzyme A + H+ ,
2.3.1.5: an arylamine + acetyl-CoA = an N-acetylarylamine + coenzyme A ,
2.3.1.8: acetyl-CoA + phosphate ↔ acetyl phosphate + coenzyme A ,
2.3.1.9: 2 acetyl-CoA ↔ acetoacetyl-CoA + coenzyme A ,
2.3.1.12: acetyl-CoA + dihydrolipoamide = S-acetyldihydrolipoamide + coenzyme A ,
2.3.1.15: a long-chain acyl-CoA + sn-glycerol 3-phosphate → a 1-acyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.16: 3-cis-dodecenoyl-CoA + acetyl-CoA = 3-keto-5-cis-tetradecenoyl-CoA + coenzyme A ,
2.3.1.16: a 2,3,4-saturated fatty acyl CoA + acetyl-CoA ← a 3-oxoacyl-CoA + coenzyme A ,
2.3.1.18: a β-D-galactoside + acetyl-CoA ↔ a 6-acetyl-β-D-galactoside + coenzyme A ,
2.3.1.29: glycine + acetyl-CoA ↔ 2-amino-3-oxobutanoate + coenzyme A ,
2.3.1.30: L-serine + acetyl-CoA → O-acetyl-L-serine + coenzyme A ,
2.3.1.46: L-homoserine + succinyl-CoA → O-succinyl-L-homoserine + coenzyme A ,
2.3.1.47: a pimeloyl-[acp] + L-alanine + H+ → 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein] ,
2.3.1.47: L-alanine + pimeloyl-CoA + H+ → CO2 + 8-amino-7-oxononanoate + coenzyme A ,
2.3.1.51: a long-chain acyl-CoA + a 1-acyl-sn-glycerol 3-phosphate → a 1,2-diacyl-sn-glycerol 3-phosphate + coenzyme A ,
2.3.1.54: formate + acetyl-CoA ← pyruvate + coenzyme A ,
2.3.1.57: acetyl-CoA + spermidine → N1-acetylspermidine + coenzyme A + H+ ,
2.3.1.57: an aliphatic α,ω-diamine + acetyl-CoA = an aliphatic N-acetyl-diamine + coenzyme A + H+ ,
2.3.1.79: maltose + acetyl-CoA ↔ acetylmaltose + coenzyme A ,
2.3.1.109: L-arginine + succinyl-CoA → N2-succinyl-L-arginine + coenzyme A + H+ ,
2.3.1.117: (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O → N-succinyl-2-amino-6-ketopimelate + coenzyme A ,
2.3.1.118: an N-hydroxy-arylamine + acetyl-CoA = an N-acetoxyarylamine + coenzyme A ,
2.3.1.157: D-glucosamine 1-phosphate + acetyl-CoA → N-acetyl-α-D-glucosamine 1-phosphate + coenzyme A + H+ ,
2.3.1.174: succinyl-CoA + acetyl-CoA ← 3-oxoadipyl-CoA + coenzyme A ,
2.3.1.210: dTDP-thomosamine + acetyl-CoA → dTDP-N-acetylthomosamine + coenzyme A + H+ ,
2.3.1.222: propanoyl-CoA + phosphate → propanoyl phosphate + coenzyme A ,
2.3.1.223: 2,3-didehydroadipyl-CoA + acetyl-CoA ← 3-oxo-5,6-didehydrosuberyl-CoA + coenzyme A ,
2.3.1.245: glycerone phosphate + acetyl-CoA ← 3-hydroxy-5-phosphonooxypentane-2,4-dione + coenzyme A ,
2.3.1.-: 2-oxobutanoate + coenzyme A → propanoyl-CoA + formate ,
2.3.1.-: a 1-palmitoyl-2-acyl-phosphatidylcholine + a lipid A → a lipid B + a 2-acyl 1-lyso-phosphatidylcholine ,
2.3.3.5: oxaloacetate + propanoyl-CoA + H2O → (2S,3S)-2-methylcitrate + coenzyme A + H+ ,
2.3.3.9: acetyl-CoA + glyoxylate + H2O → (S)-malate + coenzyme A + H+ ,
2.3.3.11: propanoyl-CoA + glyoxylate + H2O ↔ 2-hydroxyglutarate + coenzyme A + H+ ,
2.3.3.13: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2S)-2-isopropylmalate + coenzyme A + H+ ,
2.3.3.16: oxaloacetate + acetyl-CoA + H2O → citrate + coenzyme A + H+ ,
2.4.1.1: maltoheptaose + phosphate = maltohexaose + α-D-glucopyranose 1-phosphate ,
2.4.1.1: (1,4-α-D-glucosyl)(n) + phosphate ↔ (1,4-α-D-glucosyl)(n-1) + α-D-glucopyranose 1-phosphate ,
2.4.1.1: maltopentaose + phosphate = α-D-glucopyranose 1-phosphate + maltotetraose ,
2.4.1.1: maltotetraose + phosphate ↔ maltotriose + α-D-glucopyranose 1-phosphate ,
2.4.1.1: a glycogen + phosphate → an α-limit dextrin + α-D-glucopyranose 1-phosphate ,
2.4.1.1: a debranched α-limit dextrin + n phosphate → n α-D-glucopyranose 1-phosphate ,
2.4.1.1: maltohexaose + phosphate = maltopentaose + α-D-glucopyranose 1-phosphate ,
2.4.1.12: UDP-α-D-glucose + cellulose(n) = cellulose(n+1) + UDP ,
2.4.1.15: UDP-α-D-glucose + α-D-glucose 6-phosphate → UDP + α,α-trehalose 6-phosphate + H+ ,
2.4.1.17: UDP-α-D-glucuronate + glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate → UDP + glucosyl-(heptosyl)3-glucosyluronate-Kdo2-lipid A-phosphate ,
2.4.1.18: a 1,4-α-D-glucan ↔ a glycogen ,
2.4.1.21: (1,4-α-D-glucosyl)(n) + ADP-α-D-glucose ↔ ADP + (1,4-α-D-glucosyl)(n+1) ,
2.4.1.25: maltotetraose + D-glucopyranose ← maltotriose + maltose ,
2.4.1.25: maltohexaose + β-D-glucopyranose = maltopentaose + maltose ,
2.4.1.25: maltopentaose + D-glucopyranose = maltotetraose + maltose ,
2.4.1.44: UDP-α-D-galactose + glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.56: a lipopolysaccharide + UDP-N-acetyl-α-D-glucosamine = a N-acetyl-α-D-glucosaminyl-lipopolysaccharide + UDP ,
2.4.1.58: UDP-α-D-glucose + galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.58: UDP-α-D-glucose + a lipopolysaccharide = a D-glucosyl-lipopolysaccharide + UDP ,
2.4.1.73: UDP-α-D-glucose + galactosyl-glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate → galactosyl-(glucosyl)2-(heptosyl)3-Kdo2-lipid A-bisphosphate + UDP + H+ ,
2.4.1.129: [GlcNAc-(1->4)-MurNAc-pentapeptide]n-diphosphoundecaprenol + a lipid II = [GlcNAc-(1->4)-MurNAc-pentapeptide](n+1)-diphosphoundecaprenol + di-trans,octa-cis-undecaprenyl diphosphate ,
2.4.1.129: a nascent [peptidoglycan]n with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide[periplasmic space] + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[periplasmic space] → a nascent [peptidoglycan]n+1 with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide[periplasmic space] + di-trans,octa-cis-undecaprenyl diphosphate[periplasmic space] ,
2.4.1.180: N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP-N-acetyl-α-D-mannosaminuronate → N-acetyl-β-D-mannosaminuronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UDP + H+ ,
2.4.1.182: 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine → lipid A disaccharide + UDP + H+ ,
2.4.1.227: undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-α-D-glucosamine ↔ ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP + H+ ,
2.4.1.325: N-acetyl-β-D-mannosaminuronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP-N-acetylthomosamine → N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + dTDP + H+ ,
2.4.1.-: octyl α-D-glucopyranoside + UDP-α-D-galactofuranose = octyl β-1,6-D-galactofuranosyl-α-D-glucopyranoside + UDP + H+ ,
2.4.1.-: UDP-α-D-glucose + (heptosyl)2-Kdo2-lipid A → glucosyl-(heptosyl)2-Kdo2-lipid A + UDP + H+ ,
2.4.2.1: xanthosine + phosphate → α-D-ribose-1-phosphate + xanthine ,
2.4.2.1: a purine ribonucleoside + phosphate ↔ a purine base + α-D-ribose-1-phosphate ,
2.4.2.1: inosine + phosphate ↔ α-D-ribose-1-phosphate + hypoxanthine ,
2.4.2.1: adenosine + phosphate ↔ α-D-ribose-1-phosphate + adenine ,
2.4.2.1: 2'-deoxyguanosine + phosphate ↔ guanine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyinosine + phosphate ↔ hypoxanthine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.1: 2'-deoxyadenosine + phosphate ↔ adenine + 2-deoxy-α-D-ribose 1-phosphate ,
2.4.2.2/2.4.2.3: uridine + phosphate ↔ α-D-ribose-1-phosphate + uracil ,
2.4.2.2/2.4.2.4: thymidine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + thymine ,
2.4.2.3: 2'-deoxyuridine + phosphate ↔ 2-deoxy-α-D-ribose 1-phosphate + uracil ,
2.4.2.7: AMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + adenine ,
2.4.2.8: GMP + diphosphate ← guanine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.8: IMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine ,
2.4.2.9: UMP + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + uracil ,
2.4.2.10: orotidine 5'-phosphate + diphosphate ↔ 5-phospho-α-D-ribose 1-diphosphate + orotate ,
2.4.2.14: 5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + L-glutamine + H2O ,
2.4.2.15: guanosine + phosphate ↔ α-D-ribose-1-phosphate + guanine ,
2.4.2.17: 1-(5-phospho-β-D-ribosyl)-ATP + diphosphate ↔ ATP + 5-phospho-α-D-ribose 1-diphosphate + H+ ,
2.4.2.18: N-(5-phosphoribosyl)-anthranilate + diphosphate ← anthranilate + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.19: β-nicotinate D-ribonucleotide + CO2 + diphosphate ← 5-phospho-α-D-ribose 1-diphosphate + quinolinate + 2 H+ ,
2.4.2.21: β-nicotinate D-ribonucleotide + 5,6-dimethylbenzimidazole → nicotinate + α-ribazole 5'-phosphate + H+ ,
2.4.2.22: XMP + diphosphate ← xanthine + 5-phospho-α-D-ribose 1-diphosphate ,
2.4.2.43: α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A[periplasmic space] + 2 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[periplasmic space] → 4'-α-L-Ara4N-α-Kdo-(2→4)-α-Kdo-(2→6)-[P4'-α-L-ara4N]-lipid A[periplasmic space] + 2 di-trans,octa-cis-undecaprenyl phosphate[periplasmic space] ,
2.4.2.52: 3'-dephospho-CoA + ATP + H+ → 2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA + adenine ,
2.4.2.53: UDP-4-deoxy-4-formamido-β-L-arabinopyranose + di-trans,octa-cis-undecaprenyl phosphate → 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + UDP ,
2.4.2.-: phosphoribulosylformimino-AICAR-P + L-glutamine → L-glutamate + D-erythro-imidazole-glycerol-phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + H+ ,
2.4.2.-: nicotinamide + α-D-ribose-1-phosphate + H+ = 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
2.4.99.12: CMP-3-deoxy-α-D-manno-octulosonate + lipid IVA → α-Kdo-(2→6)-lipid IVA + CMP + H+ ,
2.4.99.13: α-Kdo-(2→6)-lipid IVA + CMP-3-deoxy-α-D-manno-octulosonate → α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + CMP + H+ ,
2.4.99.15: α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-α-D-manno-octulosonate = α-Kdo-(2->4)-α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + CMP + H+ ,
2.4.-.-: α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A + ADP-L-glycero-β-D-manno-heptose → heptosyl-Kdo2-lipid A + ADP + H+ ,
2.4.-.-: glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate + ADP-L-glycero-β-D-manno-heptose → glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate + ADP + H+ ,
2.4.-.-: galactosyl-(glucosyl)3-(heptosyl)3-Kdo2-lipid A-bisphosphate + ADP-L-glycero-β-D-manno-heptose → lipid A-core + ADP + H+ ,
2.5.1.1: dimethylallyl diphosphate + isopentenyl diphosphate → geranyl diphosphate + diphosphate ,
2.5.1.3: 4-methyl-5-(2-phosphonooxyethyl)thiazole + 4-amino-2-methyl-5-diphosphomethylpyrimidine + H+ → thiamin phosphate + diphosphate ,
2.5.1.3: 2-[(2R,5Z)-(2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-diphosphomethylpyrimidine + 2 H+ → thiamin phosphate + CO2 + diphosphate ,
2.5.1.6: ATP + L-methionine + H2O → S-adenosyl-L-methionine + phosphate + diphosphate ,
2.5.1.7: UDP-N-acetyl-α-D-glucosamine + phosphoenolpyruvate → UDP-N-acetyl-α-D-glucosamine-enolpyruvate + phosphate ,
2.5.1.9: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ → 5-amino-6-(D-ribitylamino)uracil + riboflavin ,
2.5.1.10: geranyl diphosphate + isopentenyl diphosphate → (2E,6E)-farnesyl diphosphate + diphosphate ,
2.5.1.15: 4-aminobenzoate + 6-hydroxymethyl-7,8-dihydropterin diphosphate → 7,8-dihydropteroate + diphosphate ,
2.5.1.16: putrescine + S-adenosyl 3-(methylthio)propylamine → spermidine + S-methyl-5'-thioadenosine + H+ ,
2.5.1.17: cobinamide + ATP → adenosylcobinamide + PPPi ,
2.5.1.17: ATP + cob(I)alamin → coenzyme B12 + PPPi ,
2.5.1.18: 1-chloro-2,4-dinitrobenzene + glutathione ↔ 2,4-dinitrophenyl-S-glutathione + chloride + H+ ,
2.5.1.19: shikimate 3-phosphate + phosphoenolpyruvate ↔ 5-enolpyruvyl-shikimate 3-phosphate + phosphate ,
2.5.1.31: (2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate ,
2.5.1.39: all-trans-octaprenyl diphosphate + 4-hydroxybenzoate → 3-octaprenyl-4-hydroxybenzoate + diphosphate ,
2.5.1.47: O-acetyl-L-serine + hydrogen sulfide ↔ L-cysteine + acetate + H+ ,
2.5.1.48: L-cysteine + O-succinyl-L-homoserine → succinate + L-cystathionine + H+ ,
2.5.1.54: phosphoenolpyruvate + D-erythrose 4-phosphate + H2O → 3-deoxy-D-arabino-heptulosonate-7-phosphate + phosphate ,
2.5.1.55: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O → 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate ,
2.5.1.61: 4 porphobilinogen + H2O → 4 ammonium + preuroporphyrinogen ,
2.5.1.72: 2-iminosuccinate + glycerone phosphate → quinolinate + phosphate + 2 H2O ,
2.5.1.74: all-trans-octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate + H+ → CO2 + demethylmenaquinol-8 + diphosphate ,
2.5.1.78: 5-amino-6-(D-ribitylamino)uracil + 1-deoxy-L-glycero-tetrulose 4-phosphate → 6,7-dimethyl-8-(1-D-ribityl)lumazine + phosphate + H+ + 2 H2O ,
2.5.1.90: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate → all-trans-octaprenyl diphosphate + 5 diphosphate ,
2.5.1.-: heme b + (2E,6E)-farnesyl diphosphate + H2O ↔ heme o + diphosphate ,
2.5.1.-: cadaverine + S-adenosyl 3-(methylthio)propylamine → aminopropylcadaverine + S-methyl-5'-thioadenosine + H+ ,
2.6.1.1: L-aspartate + 2-oxoglutarate ↔ oxaloacetate + L-glutamate ,
2.6.1.2: 2-oxoglutarate + L-alanine ↔ L-glutamate + pyruvate ,
2.6.1.3: 2-oxoglutarate + L-cysteine → L-glutamate + 3-mercaptopyruvate ,
2.6.1.6/2.6.1.42: L-leucine + 2-oxoglutarate ↔ 4-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.7: L-kynurenine + 2-oxoglutarate ↔ L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate ,
2.6.1.9: imidazole acetol-phosphate + L-glutamate → L-histidinol-phosphate + 2-oxoglutarate ,
2.6.1.11: N-acetyl-L-ornithine + 2-oxoglutarate ← N-acetyl-L-glutamate 5-semialdehyde + L-glutamate ,
2.6.1.16: β-D-fructofuranose 6-phosphate + L-glutamine ↔ D-glucosamine 6-phosphate + L-glutamate ,
2.6.1.17: 2-oxoglutarate + N-succinyl-L,L-2,6-diaminopimelate ↔ L-glutamate + N-succinyl-2-amino-6-ketopimelate ,
2.6.1.19: 2-oxoglutarate + 4-aminobutanoate ↔ L-glutamate + succinate semialdehyde ,
2.6.1.29: an aliphatic α,ω-diamine + 2-oxoglutarate ↔ an aliphatic ω-aminoaldehyde + L-glutamate ,
2.6.1.31: pyridoxamine + oxaloacetate ↔ pyridoxal + L-aspartate ,
2.6.1.42: L-isoleucine + 2-oxoglutarate ↔ (S)-3-methyl-2-oxopentanoate + L-glutamate ,
2.6.1.42: L-valine + 2-oxoglutarate ↔ 3-methyl-2-oxobutanoate + L-glutamate ,
2.6.1.52: 3-phospho-L-serine + 2-oxoglutarate ↔ 3-phospho-hydroxypyruvate + L-glutamate ,
2.6.1.52: 2-oxo-3-hydroxy-4-phosphobutanoate + L-glutamate ↔ 4-phospho-hydroxy-L-threonine + 2-oxoglutarate ,
2.6.1.57: 2-oxo-3-phenylpropanoate + L-glutamate ↔ L-phenylalanine + 2-oxoglutarate ,
2.6.1.57: an aromatic amino acid + 2-oxoglutarate ↔ an aromatic oxo-acid + L-glutamate ,
2.6.1.57: L-tyrosine + 2-oxoglutarate ↔ 4-hydroxyphenylpyruvate + L-glutamate ,
2.6.1.59: dTDP-thomosamine + 2-oxoglutarate ↔ dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + L-glutamate ,
2.6.1.62: S-adenosyl-L-methionine + 8-amino-7-oxononanoate ↔ S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminopelargonate ,
2.6.1.66: pyruvate + L-valine ↔ L-alanine + 3-methyl-2-oxobutanoate ,
2.6.1.81: N2-succinyl-L-ornithine + 2-oxoglutarate ↔ N2-succinyl-L-glutamate 5-semialdehyde + L-glutamate ,
2.6.1.82: putrescine + 2-oxoglutarate ↔ L-glutamate + 1-pyrroline + H2O ,
2.6.1.82: 4-aminobutanal ↔ 1-pyrroline + H2O ,
2.6.1.85: L-glutamine + chorismate ↔ 4-amino-4-deoxychorismate + L-glutamate ,
2.6.1.87: UDP-4-amino-4-deoxy-β-L-arabinopyranose + 2-oxoglutarate ↔ UDP-β-L-threo-pentapyranos-4-ulose + L-glutamate ,
2.6.1.88: L-methionine + a 2-oxo carboxylate = 2-oxo-4-methylthiobutanoate + a standard α amino acid ,
2.6.1.-: an aminated amino group donor + 2-oxobutanoate = 2-aminobutanoate + a deaminated amino group donor ,
2.6.99.2: 3-amino-1-hydroxyacetone 1-phosphate + 1-deoxy-D-xylulose 5-phosphate → pyridoxine 5'-phosphate + phosphate + H+ + 2 H2O ,
2.7.1.2: β-D-glucopyranose + ATP → β-D-glucose 6-phosphate + ADP + H+ ,
2.7.1.2: D-glucopyranose + ATP → D-glucopyranose 6-phosphate + ADP + H+ ,
2.7.1.4: β-D-fructofuranose + ATP → β-D-fructofuranose 6-phosphate + ADP + H+ ,
2.7.1.5: L-rhamnulofuranose + ATP → L-rhamnulose 1-phosphate + ADP + H+ ,
2.7.1.6: α-D-galactose + ATP → α-D-galactose 1-phosphate + ADP + H+ ,
2.7.1.7: D-mannopyranose + ATP → D-mannopyranose 6-phosphate + ADP + H+ ,
2.7.1.11: β-D-fructofuranose 6-phosphate + ATP → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.12: ATP + D-gluconate → ADP + D-gluconate 6-phosphate + H+ ,
2.7.1.15: α-D-ribofuranose + ATP → α-D-ribose 5-phosphate + ADP + H+ ,
2.7.1.16: L-ribulose + ATP → L-ribulose 5-phosphate + ADP + H+ ,
2.7.1.17: D-xylulose + ATP → D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.22: 1-(β-D ribofuranosyl)nicotinamide + ATP → β-nicotinamide D-ribonucleotide + ADP + H+ ,
2.7.1.23: ATP + NAD+ → ADP + NADP+ + H+ ,
2.7.1.24: 3'-dephospho-CoA + ATP → ADP + coenzyme A + H+ ,
2.7.1.25: adenosine 5'-phosphosulfate + ATP ↔ 3'-phosphoadenylyl-sulfate + ADP + H+ ,
2.7.1.26: riboflavin + ATP → ADP + FMN + H+ ,
2.7.1.30: glycerol + ATP → sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.31: D-glycerate + ATP → 3-phospho-D-glycerate + ADP + H+ ,
2.7.1.33: (R)-pantothenate + ATP → (R)-4'-phosphopantothenate + ADP + H+ ,
2.7.1.35: ATP + pyridoxal → ADP + pyridoxal 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxamine → ADP + pyridoxamine 5'-phosphate + H+ ,
2.7.1.35: ATP + pyridoxine → ADP + pyridoxine 5'-phosphate + H+ ,
2.7.1.39: L-homoserine + ATP → O-phospho-L-homoserine + ADP + H+ ,
2.7.1.40: pyruvate + ATP ← ADP + phosphoenolpyruvate + H+ ,
2.7.1.48: uridine + ATP → UMP + ADP + H+ ,
2.7.1.48: cytidine + GTP → CMP + GDP + H+ ,
2.7.1.48: uridine + GTP → UMP + GDP + H+ ,
2.7.1.48: cytidine + ATP → CMP + ADP + H+ ,
2.7.1.49: ATP + 4-amino-2-methyl-5-pyrimidinemethanol → ADP + 4-amino-2-methyl-5-phosphomethylpyrimidine + H+ ,
2.7.1.50: ATP + 4-methyl-5-(β-hydroxyethyl)thiazole → ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole + H+ ,
2.7.1.51: L-fuculose + ATP → L-fuculose 1-phosphate + ADP + H+ ,
2.7.1.53: L-xylulose + ATP → L-xylulose -5-phosphate + ADP + H+ ,
2.7.1.55: D-allopyranose + ATP → aldehydo-D-allose 6-phosphate + ADP + H+ ,
2.7.1.56: ATP + β-D-fructofuranose 1-phosphate → ADP + fructose 1,6-bisphosphate + H+ ,
2.7.1.59: N-acetyl-β-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + H+ ,
2.7.1.60: N-acetyl-D-mannosamine + ATP → N-acetyl-D-mannosamine 6-phosphate + ADP + H+ ,
2.7.1.69: HPr-Phis15 + α,α-trehalose[periplasmic space] → α,α-trehalose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + N-acetylmuramate[periplasmic space]N-acetyl-β-muramate 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + β-D-glucopyranose[periplasmic space] → β-D-glucose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + D-sorbitol[periplasmic space] → D-sorbitol 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + galactitol[periplasmic space] → galactitol 1-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + 2-O-α-mannosyl-D-glycerate[periplasmic space] → 2-O-(6-phospho-α-D-mannosyl)-D-glycerate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + L-ascorbate[periplasmic space] → L-ascorbate 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + N,N'-diacetylchitobiose[periplasmic space]N,N'-diacetylchitobiose 6'-phosphate[cytosol] + HPr ,
2.7.1.69: 2-deoxy-D-glucose[periplasmic space] + HPr-Phis15 → 2-deoxy-D-glucose 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + D-glucosamine[periplasmic space] → D-glucosamine 6-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + D-mannitol[periplasmic space] → D-mannitol 1-phosphate[cytosol] + HPr ,
2.7.1.69: HPr-Phis15 + salicin[periplasmic space] → salicin 6-phosphate[cytosol] + HPr ,
2.7.1.71: shikimate + ATP → shikimate 3-phosphate + ADP + H+ ,
2.7.1.73: inosine + ATP → IMP + ADP + H+ ,
2.7.1.73: guanosine + ATP → GMP + ADP + H+ ,
2.7.1.83: pseudouridine + ATP → pseudouridine 5'-phosphate + ADP + H+ ,
2.7.1.89: thiamin + ATP → thiamin phosphate + ADP + H+ ,
2.7.1.107: ATP + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol 3-phosphate + ADP + H+ ,
2.7.1.121: dihydroxyacetone + phosphoenolpyruvate → glycerone phosphate + pyruvate ,
2.7.1.130: lipid A disaccharide + ATP → lipid IVA + ADP + H+ ,
2.7.1.144: D-tagatofuranose 6-phosphate + ATP → D-tagatofuranose 1,6-bisphosphate + ADP + H+ ,
2.7.1.145: thymidine + ATP → dTMP + ADP + H+ ,
2.7.1.145: 2'-deoxyuridine + ATP → dUMP + ADP + H+ ,
2.7.1.148: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ATP → 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + ADP + H+ ,
2.7.1.156: adenosylcobinamide + ATP → adenosyl-cobinamide phosphate + ADP + H+ ,
2.7.1.165: ATP + D-glycerate → 2-phospho-D-glycerate + ADP + H+ ,
2.7.1.167: D-glycero-D-manno-heptose 7-phosphate + ATP → D-glycero-β-D-manno-heptose 1,7-bisphosphate + ADP + H+ ,
2.7.1.170: 1,6-anhydro-N-acetyl-β-muramate + ATP + H2O → N-acetyl-β-muramate 6-phosphate + ADP + H+ ,
2.7.1.178: 2-dehydro-3-deoxy-D-gluconate + ATP → 2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ ,
2.7.1.178: 2-dehydro-3-deoxy-D-galactonate + ATP → 2-dehydro-3-deoxy-D-galactonate 6-phosphate + ADP + H+ ,
2.7.1.184: 6-deoxy-6-sulfo-D-fructose + ATP → 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H+ ,
2.7.1.-: ATP + 1-deoxy-D-xylulose → 1-deoxy-D-xylulose 5-phosphate + ADP + H+ ,
2.7.1.-: glucosyl-(heptosyl)2-Kdo2-lipid A + ATP → glucosyl-(heptosyl)2-Kdo2-lipid A-phosphate + ADP + H+ ,
2.7.1.-: 4-hydroxy-L-threonine + ATP → 4-phospho-hydroxy-L-threonine + ADP + H+ ,
2.7.1.-: glucosyl-(heptosyl)3-Kdo2-lipid A-phosphate + ATP → glucosyl-(heptosyl)3-Kdo2-lipid A-bisphosphate + ADP + H+ ,
2.7.1.-: autoinducer 2 + ATP → (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione + ADP + H+ ,
2.7.2.1: acetate + ATP ↔ acetyl phosphate + ADP ,
2.7.2.2: ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+ ,
2.7.2.3: 3-phospho-D-glycerate + ATP ↔ 1,3-bisphospho-D-glycerate + ADP ,
2.7.2.4: L-aspartate + ATP → L-aspartyl-4-phosphate + ADP ,
2.7.2.8: N-acetyl-L-glutamate + ATP → N-acetylglutamyl-phosphate + ADP ,
2.7.2.11: L-glutamate + ATP → γ-L-glutamyl 5-phosphate + ADP ,
2.7.2.15: ATP + propanoate ↔ ADP + propanoyl phosphate ,
2.7.4.1: ATP + (polyphosphate)(n) ↔ ADP + (polyphosphate)(n+1) ,
2.7.4.3: AMP + ATP → 2 ADP ,
2.7.4.4: GTP + AMP → GDP + ADP ,
2.7.4.6: dCDP + ATP → dCTP + ADP ,
2.7.4.6: UDP + ATP → UTP + ADP ,
2.7.4.6: dUDP + ATP → dUTP + ADP ,
2.7.4.6: dADP + ATP → dATP + ADP ,
2.7.4.6: dTDP + ATP → dTTP + ADP ,
2.7.4.6: dGDP + ATP → dGTP + ADP ,
2.7.4.6: a nucleoside diphosphate + ATP → a nucleoside triphosphate + ADP ,
2.7.4.6: CDP + ATP → CTP + ADP ,
2.7.4.6: GDP + ATP → GTP + ADP ,
2.7.4.7: 4-amino-2-methyl-5-phosphomethylpyrimidine + ATP → 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP ,
2.7.4.8: GMP + ATP → GDP + ADP ,
2.7.4.12/2.7.4.13: dTMP + ATP → dTDP + ADP ,
2.7.4.13: ATP + dGMP → ADP + dGDP ,
2.7.4.14/2.7.4.25: ATP + CMP → ADP + CDP ,
2.7.4.16: thiamin phosphate + ATP → thiamin diphosphate + ADP ,
2.7.4.22: ATP + UMP → ADP + UDP ,
2.7.4.23: α-D-ribose 1,5-bisphosphate + ATP → 5-phospho-α-D-ribose 1-diphosphate + ADP ,
2.7.4.25: ATP + dCMP → ADP + dCDP ,
2.7.4.29: lipid A-core + di-trans,octa-cis-undecaprenyl diphosphate = lipid A-core 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate ,
2.7.4.29: α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate = α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate ,
2.7.6.1: D-ribose 5-phosphate + ATP → 5-phospho-α-D-ribose 1-diphosphate + AMP + H+ ,
2.7.6.3: 6-hydroxymethyl-7,8-dihydropterin + ATP → 6-hydroxymethyl-7,8-dihydropterin diphosphate + AMP + H+ ,
2.7.6.5: GTP + ATP → pppGpp + AMP ,
2.7.6.5: ATP + GDP → AMP + ppGpp ,
2.7.7.1: β-nicotinamide D-ribonucleotide + ATP + H+ → NAD+ + diphosphate ,
2.7.7.2: ATP + FMN + H+ → FAD + diphosphate ,
2.7.7.3: 4'-phosphopantetheine + ATP + H+ → 3'-dephospho-CoA + diphosphate ,
2.7.7.4: sulfate + ATP + H+ → adenosine 5'-phosphosulfate + diphosphate ,
2.7.7.12: UDP-α-D-glucose + α-D-galactose 1-phosphate ↔ UDP-α-D-galactose + α-D-glucopyranose 1-phosphate ,
2.7.7.13: α-D-mannose 1-phosphate + GTP + H+ → GDP-α-D-mannose + diphosphate ,
2.7.7.18: ATP + β-nicotinate D-ribonucleotide + H+ → nicotinate adenine dinucleotide + diphosphate ,
2.7.7.23: N-acetyl-α-D-glucosamine 1-phosphate + UTP + H+ → UDP-N-acetyl-α-D-glucosamine + diphosphate ,
2.7.7.24: α-D-glucopyranose 1-phosphate + dTTP + H+ ↔ dTDP-α-D-glucose + diphosphate ,
2.7.7.27: α-D-glucopyranose 1-phosphate + ATP + H+ → ADP-α-D-glucose + diphosphate ,
2.7.7.38: 3-deoxy-D-manno-octulosonate + CTP → CMP-3-deoxy-α-D-manno-octulosonate + diphosphate ,
2.7.7.41: CTP + a 1,2-diacyl-sn-glycerol 3-phosphate + H+ → a CDP-diacylglycerol + diphosphate ,
2.7.7.41: CTP + a 2,3,4-saturated L-phosphatidate + H+ → a CDP-2,3,4-saturated-diacylglycerol + diphosphate ,
2.7.7.56: a tRNA precursor with a 5' extension and a short 3' extension + n phosphate → a tRNA precursor with a 5' extension + a ribonucleoside diphosphate ,
2.7.7.58: ATP + 2,3-dihydroxybenzoate + H+ → 2,3-dihydroxybenzoyl adenylate + diphosphate ,
2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate + CTP + H+ → 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol + diphosphate ,
2.7.7.62: adenosyl-cobinamide phosphate + GTP + H+ → adenosylcobinamide-GDP + diphosphate ,
2.7.7.63: ATP + (R)-lipoate + H+ → lipoyl-adenylate + diphosphate ,
2.7.7.64: α-D-glucopyranose 1-phosphate + UTP + H+ → UDP-α-D-glucose + diphosphate ,
2.7.7.65: 2 GTP → cyclic di-3',5'-guanylate + 2 diphosphate ,
2.7.7.70: D-glycero-β-D-manno-heptose 1-phosphate + ATP + H+ → ADP-D-glycero-β-D-manno-heptose + diphosphate ,
2.7.7.75: ATP + molybdopterin + H+ → molybdopterin adenine dinucleotide + diphosphate ,
2.7.7.76: CTP + MoO2-molybdopterin cofactor + H+ → cytidylyl molybdenum cofactor + diphosphate ,
2.7.7.77: 2 GTP + bis(molybdenum cofactor) + 2 H+ = bis(guanylyl molybdopterin cofactor) + 2 diphosphate ,
2.7.7.77: GTP + MoO2-molybdopterin cofactor + H+ → guanylyl molybdenum cofactor + diphosphate ,
2.7.7.-: an insertion sequence element IS30 = an insertion sequence IS30 with integrated transposon ,
2.7.7.-: a single stranded DNA = a short RNA Segment ,
2.7.7.-: ATP + ADP + H+ → 5',5'''-diadenosine triphosphate + diphosphate ,
2.7.7.-: thiamin diphosphate + ADP + H+ ↔ adenosine thiamine triphosphate + phosphate ,
2.7.7.-: ATP + ATP + H+ = 5',5'''-diadenosine tetraphosphate + diphosphate ,
2.7.8.5: a CDP-diacylglycerol + sn-glycerol 3-phosphate ↔ CMP + an L-1-phosphatidylglycerol-phosphate + H+ ,
2.7.8.8: a CDP-diacylglycerol + L-serine ↔ CMP + an L-1-phosphatidylserine + H+ ,
2.7.8.13: UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate → undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP ,
2.7.8.20: an osmoregulated periplasmic glucan[periplasmic space] + an L-1-phosphatidyl-glycerol[periplasmic space] ↔ an osmoregulated periplasmic glucan with phosphoglycerol substituent[periplasmic space] + a 1,2-diacyl-sn-glycerol[periplasmic space] + H+[periplasmic space] ,
2.7.8.21: an osmoregulated periplasmic glucan with phosphoglycerol substituent[periplasmic space] + an osmoregulated periplasmic glucan[periplasmic space] ↔ an osmoregulated periplasmic glucan[periplasmic space] + an osmoregulated periplasmic glucan with phosphoglycerol substituent[periplasmic space] ,
2.7.8.26: adenosylcobinamide-GDP + α-ribazole 5'-phosphate → adenosylcobalamin 5'-phosphate + GMP + H+ ,
2.7.8.31: UDP-α-D-glucose + di-trans,octa-cis-undecaprenyl phosphate = UMP + α-D-glucopyranosyl-diphosphoundecaprenol ,
2.7.8.33: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol + UMP ,
2.7.8.37: methylphosphonate + ATP → α-D-ribose-1-methylphosphonate-5-triphosphate + adenine ,
2.7.8.-: an L-1-phosphatidylethanolamine[periplasmic space] + α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA[periplasmic space] = a 1,2-diacyl-sn-glycerol[periplasmic space] + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid IVA[periplasmic space] ,
2.7.8.-: an L-1-phosphatidylethanolamine + α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A = a 1,2-diacyl-sn-glycerol + 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A ,
2.7.8.-: 2 an L-1-phosphatidyl-glycerol → a cardiolipin + glycerol ,
2.7.9.2: pyruvate + ATP + H2O → phosphoenolpyruvate + AMP + phosphate + 2 H+ ,
2.7.9.3: selenide + ATP + H2O → selenophosphate + AMP + phosphate ,
2.7.10.2/2.7.12.1: ATP + a [protein]-L-tyrosine → ADP + a [protein]-L-tyrosine phosphate + H+ ,
2.8.1.1: a sulfurated [sulfur carrier] + hydrogen cyanide → an unsulfurated [sulfur carrier] + thiocyanate + H+ ,
2.8.1.1: hydrogen cyanide + thiosulfate → thiocyanate + sulfite + 2 H+ ,
2.8.1.2: hydrogen cyanide + 3-mercaptopyruvate → pyruvate + thiocyanate + H+ ,
2.8.1.6: a sulfurated [sulfur carrier] + dethiobiotin + 2 S-adenosyl-L-methionine + 2 a reduced [2Fe-2S] ferredoxin → an unsulfurated [sulfur carrier] + biotin + 2 5'-deoxyadenosine + 2 L-methionine + 2 an oxidized [2Fe-2S] ferredoxin ,
2.8.1.7: L-cysteine + an unsulfurated [sulfur carrier] → L-alanine + a sulfurated [sulfur carrier] ,
2.8.1.7: L-cystein desulfurase + L-cysteine = an S-sulfanyl-[L-cysteine desulfurase] + L-alanine ,
2.8.1.7: an [L-cysteine desulfurase] L-cysteine persulfide + an unsulfurated [sulfur carrier] ↔ an [L-cysteine desulfurase]-L-cysteine + a sulfurated [sulfur carrier] ,
2.8.1.7: an [L-cysteine desulfurase]-L-cysteine + L-cysteine → an [L-cysteine desulfurase] L-cysteine persulfide + L-alanine ,
2.8.1.12: cyclic pyranopterin phosphate + 2 a thiocarboxylated small subunit of molybdopterin synthase + H2O → 2 a small subunit of molybdopterin synthase + molybdopterin + 4 H+ ,
2.8.1.-: a uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + an reduced unknown electron acceptor → a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized unknown electron acceptor + diphosphate + H+ ,
2.8.3.8: a 2,3,4-saturated fatty acyl CoA + acetate ↔ a 2,3,4-saturated fatty acid + acetyl-CoA ,
2.8.3.16: formyl-CoA + oxalate = formate + oxalyl-CoA ,
2.8.3.19: acetyl-CoA + oxalate = oxalyl-CoA + acetate ,
2.8.3.21: L-carnitine + γ-butyrobetainyl-CoA → L-carnitinyl-CoA + γ-butyrobetaine ,
2.8.3.-: acetoacetate + acetyl-CoA ↔ acetoacetyl-CoA + acetate ,
2.8.3.-: propanoyl-CoA + succinate ↔ propanoate + succinyl-CoA ,
2.8.4.3: N6-dimethylallyladenosine37 in tRNA + 2 S-adenosyl-L-methionine + a sulfurated [sulfur carrier] + an reduced unknown electron acceptor → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + an unsulfurated [sulfur carrier] + 5'-deoxyadenosine + L-methionine + an oxidized unknown electron acceptor + 2 H+ ,
2.10.1.1: molybdopterin adenine dinucleotide + molybdate + H+ → AMP + MoO2-molybdopterin cofactor + H2O ,
2.-.-.-: heptosyl-Kdo2-lipid A + ADP-L-glycero-β-D-manno-heptose → (heptosyl)2-Kdo2-lipid A + ADP + H+ ,
3.1.1.1: a carboxylic ester + H2O → an alcohol + a carboxylate + H+ ,
3.1.1.4: an L-1-phosphatidylethanolamine[periplasmic space] + H2O[periplasmic space] → a fatty acid[periplasmic space] + a 1-acyl 2-lyso-phosphatidylethanolamine[periplasmic space] + H+[periplasmic space] ,
3.1.1.5: a 1-acyl 2-lyso-phosphatidylcholine + H2O → a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.6: an acetic ester + H2O → an alcohol + acetate + H+ ,
3.1.1.17: D-glucono-1,5-lactone + H2O → D-gluconate + H+ ,
3.1.1.25: D-galactono-1,4-lactone + H2O → D-galactonate + H+ ,
3.1.1.31: 6-phospho D-glucono-1,5-lactone + H2O → D-gluconate 6-phosphate + H+ ,
3.1.1.32: an L-1-phosphatidylethanolamine[periplasmic space] + H2O[periplasmic space] → a 2-acyl-1-lyso-phosphatidylethanolamine[periplasmic space] + a fatty acid[periplasmic space] + H+[periplasmic space] ,
3.1.1.-: (2,3-dihydroxybenzoylserine)2 + H2O → 2 N-(2,3-dihydroxybenzoyl)-L-serine + H+ ,
3.1.1.-: enterobactin + 3 H2O → 3 N-(2,3-dihydroxybenzoyl)-L-serine + 3 H+ ,
3.1.1.-: ferric enterobactin complex + H2O → ferric (2,3-dihydroxybenzoylserine)3 ,
3.1.1.-: L-ascorbate 6-phosphate + H2O → 3-keto-L-gulonate 6-phosphate ,
3.1.1.-: (2,3-dihydroxybenzoylserine)3 + H2O → (2,3-dihydroxybenzoylserine)2 + N-(2,3-dihydroxybenzoyl)-L-serine + H+ ,
3.1.1.-: a 2-acyl 1-lyso-phosphatidylcholine + H2O = a carboxylate + sn-glycero-3-phosphocholine + H+ ,
3.1.1.-: enterobactin + H2O → (2,3-dihydroxybenzoylserine)3 + H+ ,
3.1.2.2: a 2,3,4-saturated fatty acyl CoA[periplasmic space] + H2O[periplasmic space] → a 2,3,4-saturated fatty acid[periplasmic space] + coenzyme A[periplasmic space] + H+[periplasmic space] ,
3.1.2.6: (R)-S-lactoylglutathione + H2O → glutathione + (R)-lactate + H+ ,
3.1.2.12: S-formylglutathione + H2O → formate + glutathione + H+ ,
3.1.2.16: an acetyl-[holo citrate lyase acyl-carrier protein] + H2O → [a holo citrate lyase acyl-carrier protein] + acetate + H+ ,
3.1.2.20: an acyl-CoA + H2O → a carboxylate + coenzyme A + H+ ,
3.1.2.28: 1,4-dihydroxy-2-naphthoyl-CoA + H2O → 1,4-dihydroxy-2-naphthoate + coenzyme A + H+ ,
3.1.2.-: 3-hydroxybenzoyl-CoA + H2O → 3-hydroxybenzoate + coenzyme A + H+ ,
3.1.2.-: 3-trans,5-cis-tetradecadienoyl-CoA + H2O → (3E,5Z)-tetradecadienoate + coenzyme A + H+ ,
3.1.3.1: a phosphate monoester[periplasmic space] + H2O[periplasmic space] → an alcohol[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.2: a phosphate monoester[periplasmic space] + H2O[periplasmic space] → an alcohol[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.3: 3-phospho-L-serine + H2O → L-serine + phosphate ,
3.1.3.5: AMP + H2O → adenosine + phosphate ,
3.1.3.5: a ribonucleoside 5'-monophosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.5: IMP + H2O → inosine + phosphate ,
3.1.3.5: UMP + H2O → uridine + phosphate ,
3.1.3.5: GMP + H2O → guanosine + phosphate ,
3.1.3.5: β-nicotinamide D-ribonucleotide + H2O → 1-(β-D ribofuranosyl)nicotinamide + phosphate ,
3.1.3.6: guanosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.6: cytidine-3'-monophosphate + H2O → cytidine + phosphate ,
3.1.3.6: a ribonucleoside 3'-phosphate + H2O → a ribonucleoside + phosphate ,
3.1.3.6: adenosine 3'-monophosphate + H2O → adenosine + phosphate ,
3.1.3.6: uridine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → uridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.7: adenosine 3',5'-bisphosphate + H2O → AMP + phosphate ,
3.1.3.8: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate[periplasmic space] + H2O[periplasmic space] → D-myo-inositol (1,2,4,5,6)-pentakisphosphate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.10: α-D-glucopyranose 1-phosphate + H2O → D-glucopyranose + phosphate ,
3.1.3.11: fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate ,
3.1.3.12: α,α-trehalose 6-phosphate + H2O → α,α-trehalose + phosphate ,
3.1.3.15: L-histidinol-phosphate + H2O → histidinol + phosphate ,
3.1.3.18: 2-phosphoglycolate + H2O → glycolate + phosphate ,
3.1.3.19: glycerol 2-phosphate + H2O → glycerol + phosphate ,
3.1.3.20: 2-phospho-D-glycerate[periplasmic space] + H2O[periplasmic space] → D-glycerate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.21: glycerol 1-phosphate + H2O → glycerol + phosphate ,
3.1.3.23: a sugar phosphate + H2O → a sugar + phosphate ,
3.1.3.25: 1D-myo-inositol 1-monophosphate + H2O → myo-inositol + phosphate ,
3.1.3.27: an L-1-phosphatidylglycerol-phosphate + H2O → an L-1-phosphatidyl-glycerol + phosphate ,
3.1.3.34: 2'-deoxyguanosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyguanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxycytidine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxycytidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: a 2'-deoxyribonucleoside 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → a 2'-deoxynucleoside[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxyuridine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyuridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: 2'-deoxyadenosine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → 2'-deoxyadenosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.34: thymidine 3'-monophosphate[periplasmic space] + H2O[periplasmic space] → thymidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.41: 4-nitrophenyl phosphate[periplasmic space] + H2O[periplasmic space] → 4-nitrophenol[periplasmic space] + phosphate[periplasmic space] + H+[periplasmic space] ,
3.1.3.45: 3-deoxy-D-manno-octulosonate 8-phosphate + H2O → 3-deoxy-D-manno-octulosonate + phosphate ,
3.1.3.58: β-D-glucose 6-phosphate + H2O → β-D-glucopyranose + phosphate ,
3.1.3.58: α-D-glucose 6-phosphate + H2O → α-D-glucose + phosphate ,
3.1.3.58: D-glucopyranose 6-phosphate[periplasmic space] + H2O[periplasmic space] → D-glucopyranose[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.60: phosphoenolpyruvate[periplasmic space] + H2O[periplasmic space] → pyruvate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.62: 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate[periplasmic space] + H2O[periplasmic space] → D-myo-inositol (1,2,3,4,5)-pentakisphosphate[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.68: 2-deoxy-D-glucose 6-phosphate + H2O → 2-deoxy-D-glucose + phosphate ,
3.1.3.73: α-ribazole 5'-phosphate + H2O → α-ribazole + phosphate ,
3.1.3.73: adenosylcobalamin 5'-phosphate + H2O → coenzyme B12 + phosphate ,
3.1.3.74: pyridoxine 5'-phosphate[periplasmic space] + H2O[periplasmic space] → pyridoxine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.74: pyridoxal 5'-phosphate + H2O → pyridoxal + phosphate ,
3.1.3.75: O-phosphoethanolamine[periplasmic space] + H2O[periplasmic space] → ethanolamine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.75: phosphocholine[periplasmic space] + H2O[periplasmic space] → choline[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.81: a 1,2-diacyl-sn-glycerol 3-diphosphate[periplasmic space] + H2O[periplasmic space] → a 1,2-diacyl-sn-glycerol 3-phosphate[periplasmic space] + phosphate[periplasmic space] + H+[periplasmic space] ,
3.1.3.82: D-glycero-β-D-manno-heptose 1,7-bisphosphate + H2O → D-glycero-β-D-manno-heptose 1-phosphate + phosphate ,
3.1.3.89: dTMP + H2O → thymidine + phosphate ,
3.1.3.89: dAMP + H2O → 2'-deoxyadenosine + phosphate ,
3.1.3.89: dGMP + H2O → 2'-deoxyguanosine + phosphate ,
3.1.3.89: a 2'-deoxyribonucleoside 5'-monophosphate + H2O → a 2'-deoxynucleoside + phosphate ,
3.1.3.89: dUMP + H2O → 2'-deoxyuridine + phosphate ,
3.1.3.89: dCMP + H2O → 2'-deoxycytidine + phosphate ,
3.1.3.91: CMP + H2O → cytidine + phosphate ,
3.1.3.97: a nucleoside 3',5'-bisphosphate + H2O → a nucleoside 5'-monophosphate + phosphate ,
3.1.3.-: uridine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → uridine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: adenosine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → adenosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: β-D-fructofuranose 1-phosphate + H2O → β-D-fructofuranose + phosphate ,
3.1.3.-: a hexose phosphate + H2O = a hexose + phosphate ,
3.1.3.-: NADP+ + H2O → NAD+ + phosphate ,
3.1.3.-: D-ribose 5-phosphate[periplasmic space] + H2O[periplasmic space]aldehydo-D-ribose[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: guanosine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: D-gluconate 6-phosphate + H2O → D-gluconate + phosphate ,
3.1.3.-: L-threonine 3-O-phosphate[periplasmic space] + H2O[periplasmic space] → L-threonine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: cytidine 2'-monophosphate[periplasmic space] + H2O[periplasmic space] → cytidine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: cysteamine S-phosphate[periplasmic space] + H2O[periplasmic space] → cysteamine[periplasmic space] + phosphate[periplasmic space] ,
3.1.3.-: FMN + H2O → riboflavin + phosphate ,
3.1.4.16: a nucleoside 2',3'-cyclic phosphate[periplasmic space] + H2O[periplasmic space] → a ribonucleoside 3'-phosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: adenosine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → adenosine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: guanosine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → guanosine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: uridine 2'3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → uridine 3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.16: cytidine 2',3'-cyclic monophosphate[periplasmic space] + H2O[periplasmic space] → cytidine-3'-monophosphate[periplasmic space] + H+[periplasmic space] ,
3.1.4.46: sn-glycero-3-phosphoethanolamine + H2O → sn-glycerol 3-phosphate + ethanolamine + H+ ,
3.1.4.46: glycerophosphoglycerol + H2O → glycerol + sn-glycerol 3-phosphate + H+ ,
3.1.4.46: glycerophosphoserine + H2O → sn-glycerol 3-phosphate + L-serine + H+ ,
3.1.4.46: a glycerophosphodiester + H2O → an alcohol + sn-glycerol 3-phosphate + H+ ,
3.1.4.52: cyclic di-3',5'-guanylate + H2O → linear dimeric GMP + H+ ,
3.1.4.53: cyclic-AMP + H2O → AMP + H+ ,
3.1.4.55: 5-phospho-α-D-ribose 1,2-cyclic phosphate + H2O → α-D-ribose 1,5-bisphosphate + H+ ,
3.1.5.1: dGTP + H2O → PPPi + 2'-deoxyguanosine + H+ ,
3.1.6.1: a phenol sulfate + H2O → a phenol + sulfate + H+ ,
3.1.6.-: dodecyl sulfate + H2O → 1-dodecanol + sulfate + H+ ,
3.1.7.2: ppGpp + H2O → GDP + diphosphate + H+ ,
3.1.7.2: pppGpp + H2O → GTP + diphosphate + H+ ,
3.1.11.1: DNAn + H2O → (deoxynucleotides)(n-1) + a 2'-deoxyribonucleoside 5'-monophosphate ,
3.1.11.6: a single stranded DNA + H2O → a ribonucleoside 5'-monophosphate + a single-stranded oligodeoxyribonucleotide ,
3.1.11.-: DNAn + n H2O → n a nucleoside 5'-monophosphate ,
3.1.11.-: a double stranded DNA + H2O → a single stranded DNA + a 5'-phosphomononucleotide ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + n H2O → a tRNA precursor with a 5' extension and a short 3' extension + n a nucleoside 5'-monophosphate ,
3.1.13.1: a tRNA precursor with a 5' extension and a long 3' trailer + H2O → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.1: RNase II degradation substrate mRNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.13.3: an oligonucleotide + H2O → n a nucleoside 5'-monophosphate ,
3.1.13.5: a tRNA precursor with a 5' extension and a short 3' extension → a tRNA precursor with a 5' extension + a ribonucleoside 5'-monophosphate ,
3.1.13.-: RNase R degradation substrate RNA + n-1 H2O → n-2 a nucleoside 5'-monophosphate + a diribonucleotide ,
3.1.13.-: RNA + n H2O → n a nucleoside 5'-monophosphate ,
3.1.21.1: a double stranded DNA[periplasmic space] + n H2O[periplasmic space] → n+1 a 5'-phosphooligonucleotide[periplasmic space] ,
3.1.21.2: a single stranded DNA + n H2O → n a 5'-phosphooligonucleotide ,
3.1.21.3: ATP + DNAn + H2O → a double stranded DNA with 5'-terminal phosphate + ADP + phosphate ,
3.1.21.7: DNAn + H2O → a 3'-hydroxy terminated DNA + a 5'-phospho terminated DNA ,
3.1.26.3: RNase III mRNA processing substrate + 2 H2O → RNase III processing product mRNA + 2 a single-stranded RNA ,
3.1.26.5: a tRNA precursor with a 5' extension and a short 3' extension + H2O → a tRNA precursor with a short 3' extension + a single-stranded RNA ,
3.1.26.11: a tRNA precursor + H2O → mature tRNA + a single-stranded oligoribonucleotide ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a long 3' trailer + a partially processed polycistronic tRNA precursor ,
3.1.26.12: a polycistronic tRNA precursor + H2O → a tRNA precursor with a 5' extension and a short 3' extension + a partially processed polycistronic tRNA precursor ,
3.1.27.6: an mRNA[periplasmic space] + H2O[periplasmic space] → 2 a single-stranded RNA[periplasmic space] ,
3.1.27.-: RNA + H2O → 2',3' -cyclic nucleotide phosphate + a 3' phosphooligonucleotide ,
3.2.1.1: a 1,4-α-D-glucan[periplasmic space] + n H2O[periplasmic space] → a 1,4-α-D-glucan[periplasmic space] + maltohexaose[periplasmic space] ,
3.2.1.1: a 1,4-α-D-glucan + n H2O → n a 1,4-α-D-glucan ,
3.2.1.14: EC 3.2.1.14 ,
3.2.1.17: a peptidoglycan + H2O → a N-acetylmuramoyl-pentapeptide-diphosphoundecaprenol + N-acetyl-D-glucosamine ,
3.2.1.20: maltoheptaose + H2O → maltohexaose + α-D-glucose ,
3.2.1.20: (1,4-α-D-glucosyl)(n) + H2O → (1,4-α-D-glucosyl)(n-1) + D-glucopyranose ,
3.2.1.20: maltopentaose + H2O → maltotetraose + D-glucopyranose ,
3.2.1.20: maltohexaose + H2O → maltopentaose + α-D-glucose ,
3.2.1.20: maltotriose + H2O → maltose + D-glucopyranose ,
3.2.1.21: a β-D glucoside[periplasmic space] + H2O[periplasmic space] → a non glucosylated D-glucose acceptor[periplasmic space] + β-D-glucopyranose[periplasmic space] ,
3.2.1.22: melibiose + H2O → α-D-galactose + β-D-glucopyranose ,
3.2.1.23: α-lactose + H2O → β-D-galactose + β-D-glucopyranose ,
3.2.1.28: α,α-trehalose + H2O → β-D-glucopyranose + α-D-glucose ,
3.2.1.31: a β-D-glucuronoside + H2O → D-glucopyranuronate + an alcohol ,
3.2.1.42: GDP-α-D-glucose + H2O → β-D-glucopyranose + GDP + H+ ,
3.2.1.52: N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + H2O → N-acetyl-β-D-glucosamine + 1,6-anhydro-N-acetyl-β-muramate ,
3.2.1.52: an N-acetyl-β-D-hexosaminide + H2O → an N-acetyl-β-D-hexosamine + an alcohol ,
3.2.1.86: methyl β-D-glucoside 6-phosphate + H2O → β-D-glucose 6-phosphate + methanol ,
3.2.1.86: arbutin-6-phosphate + H2O → β-D-glucose 6-phosphate + benzene-1,4-diol ,
3.2.1.86: β-D-cellobiose 6'-phosphate + H2O → β-D-glucose 6-phosphate + β-D-glucopyranose ,
3.2.1.86: salicin 6-phosphate + H2O → β-D-glucose 6-phosphate + salicyl alcohol ,
3.2.1.86: N-monoacetylchitobiose 6'-phosphate + H2O → N-acetyl-D-glucosamine 6-phosphate + D-glucosamine ,
3.2.1.93: α,α-trehalose 6-phosphate + H2O → β-D-glucose 6-phosphate + D-glucopyranose ,
3.2.1.170: 2-O-(6-phospho-α-D-mannosyl)-D-glycerate + H2O → D-mannopyranose 6-phosphate + D-glycerate ,
3.2.1.177: xylan + n H2O → n α-D-xylopyranose ,
3.2.1.177: isoprimeverose + H2O → β-D-glucopyranose + α-D-xylopyranose ,
3.2.1.-: an α-limit dextrin + H2O → a debranched α-limit dextrin + maltotetraose ,
3.2.1.-: GDP-α-D-mannose + H2O → D-mannose + GDP + H+ ,
3.2.1.-: nigerose + H2O → 2 α-D-glucose ,
3.2.2.1: xanthosine + H2O → D-ribofuranose + xanthine ,
3.2.2.2: inosine + H2O → D-ribofuranose + hypoxanthine ,
3.2.2.3: uridine + H2O → D-ribofuranose + uracil ,
3.2.2.3: cytidine + H2O → D-ribofuranose + cytosine ,
3.2.2.4: AMP + H2O → D-ribofuranose 5-phosphate + adenine ,
3.2.2.5: NAD+ + H2O → ADP-D-ribose + nicotinamide + H+ ,
3.2.2.7: adenosine + H2O → D-ribofuranose + adenine ,
3.2.2.8: a pyrimidine nucleoside + H2O + H+ → a pyrimidine base + D-ribofuranose ,
3.2.2.9: S-adenosyl-L-homocysteine + H2O → S-ribosyl-L-homocysteine + adenine ,
3.2.2.14: β-nicotinamide D-ribonucleotide + H2O → D-ribofuranose 5-phosphate + nicotinamide + H+ ,
3.2.2.16: S-methyl-5'-thioadenosine + H2O → S-methyl-5-thio-D-ribose + adenine ,
3.2.2.21: an alkylated DNA + H2O → DNAn + an alkylated nucleobase ,
3.2.2.23: a DNA containing ring-opened 7-methylguanine + H2O → 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine + a DNA containing an apurinic site ,
3.2.2.28: DNA containing a base with lesion + H2O → a DNA containing an apurinic/apyrimidinic site + base with lesion ,
3.3.2.1: isochorismate + H2O → pyruvate + (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate ,
3.3.2.12: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O → 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde ,
3.4.11.2: a polypeptide + H2O → a polypeptide + an L-amino acid ,
3.4.11.4: a tripeptide + H2O → a dipeptide + a standard α amino acid ,
3.4.11.9: a peptide + H2O → a standard α amino acid + a peptide ,
3.4.11.18: a peptide with an N-terminal L-methionine + H2O → L-methionine + a peptide + H+ ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.11.-: a polypeptide + H2O → 2 a polypeptide ,
3.4.11.-: a protein + H2O → a peptide + a standard α amino acid ,
3.4.11.-: a [protein] N-terminal L-arginine[periplasmic space] + H2O[periplasmic space] → a protein[periplasmic space] + L-arginine[periplasmic space] + H+[periplasmic space] ,
3.4.13.9: a dipeptide with proline at the C-terminal + H2O → L-proline + a standard α amino acid ,
3.4.13.18: glycyl-L-aspartate + H2O → glycine + L-aspartate ,
3.4.13.18: glycyl-L-glutamine + H2O → glycine + L-glutamine ,
3.4.13.18: L-alanyl-L-threonine + H2O → L-alanine + L-threonine ,
3.4.13.18: L-alanyl-glycine + H2O → L-alanine + glycine ,
3.4.13.18: glycyl-L-methionine + H2O → glycine + L-methionine ,
3.4.13.18: glycyl-L-proline + H2O → glycine + L-proline ,
3.4.13.18: glycyl-L-glutamate + H2O → glycine + L-glutamate ,
3.4.13.18: L-cysteinyl-glycine + H2O → L-cysteine + glycine ,
3.4.13.18: L-alanyl-L-glutamate + H2O → L-alanine + L-glutamate ,
3.4.13.18: L-alanyl-L-histidine + H2O → L-alanine + L-histidine ,
3.4.13.18: L-alanyl-L-aspartate + H2O → L-alanine + L-aspartate ,
3.4.13.18: a dipeptide + H2O → 2 a standard α amino acid ,
3.4.13.18: L-methionyl-L-alanine dipeptide + H2O → L-methionine + L-alanine ,
3.4.13.18: glycyl-L-asparagine + H2O → glycine + L-asparagine ,
3.4.13.18: L-alanyl-L-leucine + H2O → L-alanine + L-leucine ,
3.4.13.18: L-alanyl-L-glutamine + H2O → L-alanine + L-glutamine ,
3.4.13.21: a dipetide with an N-terminal L-aspartate + H2O → L-aspartate + a standard α amino acid ,
3.4.13.22: D-alanyl-D-alanine + H2O → 2 D-alanine ,
3.4.15.5: an oligopeptide[periplasmic space] + H2O[periplasmic space] → a peptide[periplasmic space] + a dipeptide[periplasmic space] ,
3.4.16.4: a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + a peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide → a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine ,
3.4.16.4: a nascent [peptidoglycan]n with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide[periplasmic space] + H2O[periplasmic space] → a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide[periplasmic space] + D-alanine[periplasmic space] ,
3.4.17.13: L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine ,
3.4.17.13: a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide[periplasmic space] + H2O[periplasmic space] → a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide[periplasmic space] + D-alanine[periplasmic space] ,
3.4.19.12: an N6-monoubiquitinyl-[protein]-L-lysine + H2O → a [protein]-L-lysine + a [ubiquitin] C-terminal glycine ,
3.4.19.13: glutathione[periplasmic space] + H2O[periplasmic space] → L-cysteinyl-glycine[periplasmic space] + L-glutamate[periplasmic space] ,
3.4.19.-: β-aspartyl dipeptide + H2O → L-aspartate + a standard α amino acid ,
3.4.21.53: a protein + H2O → a peptide + a peptide ,
3.4.21.83: an oligopeptide + H2O → a peptide + a peptide ,
3.4.21.89: a peptide with a leader sequence + H2O → a peptide + a leader sequence ,
3.4.21.92: a protein + H2O → a peptide + a peptide ,
3.4.21.102: a protein[periplasmic space] + H2O[periplasmic space] → a peptide[periplasmic space] + a peptide[periplasmic space] ,
3.4.21.-: a polypeptide[periplasmic space] + H2O[periplasmic space] → 2 a polypeptide[periplasmic space] ,
3.4.21.-: a protein + H2O → a peptide + a peptide ,
3.4.21.-: a cleaved lipoprotein signal peptide + H2O → n a peptide ,
3.4.23.36: a prolipoprotein + H2O → a lipoprotein + a cleaved lipoprotein signal peptide ,
3.4.23.43: a type IV prepilin + H2O → a cleaved type IV prepilin + a peptide ,
3.4.23.49: a protein + H2O → a peptide + a peptide ,
3.4.23.51: a precursor of large subunit of hydrogenase 3 + H2O → a C terminal 32 amino-acid peptide + a large subunit of hydrogenase 3 ,
3.4.24.55: a protein + H2O → n a peptide ,
3.4.24.70: an oligopeptide + H2O → a peptide + a peptide ,
3.4.24.-: a protein + H2O → a peptide + a peptide ,
3.4.-.-: peptidoglycan D-alanyl-DAP crosslink[periplasmic space] + H2O[periplasmic space] → peptidoglycan tetrapeptide, glycan chain 2[periplasmic space] + peptidoglycan tetrapeptide, glycan chain 1[periplasmic space] ,
3.4.-.-: peptidoglycan DAP-DAP crosslink[periplasmic space] + H2O[periplasmic space] + H+[periplasmic space] → peptidoglycan tripeptide, glycan chain 1[periplasmic space] + peptidoglycan tetrapeptide, glycan chain 2[periplasmic space] ,
3.5.1.10: an N10-formyl-tetrahydrofolate + H2O → a tetrahydrofolate + formate + H+ ,
3.5.1.16: N-acetyl-L-ornithine + H2O → L-ornithine + acetate ,
3.5.1.18: N-succinyl-L,L-2,6-diaminopimelate + H2O ↔ L,L-diaminopimelate + succinate ,
3.5.1.19: nicotinamide + H2O → ammonium + nicotinate ,
3.5.1.25: N-acetyl-D-glucosamine 6-phosphate + H2O → D-glucosamine 6-phosphate + acetate ,
3.5.1.28: GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala + H2O → N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine ,
3.5.1.38: L-asparagine + H2O → L-aspartate + ammonium ,
3.5.1.38: L-glutamine + H2O → L-glutamate + ammonium ,
3.5.1.42: β-nicotinamide D-ribonucleotide + H2O → ammonium + β-nicotinate D-ribonucleotide ,
3.5.1.78: glutathionylspermidine + H2O → glutathione + spermidine ,
3.5.1.88: a [protein] N-terminal-formyl-L-methionine + H2O → a [protein] N-terminal L-methionine + formate ,
3.5.1.94: 4-(γ-L-glutamylamino)butanoate + H2O → 4-aminobutanoate + L-glutamate ,
3.5.1.96: N2-succinylglutamate + H2O → succinate + L-glutamate ,
3.5.1.105: N,N'-diacetylchitobiose 6'-phosphate + H2O → N-monoacetylchitobiose 6'-phosphate + acetate ,
3.5.1.105: N,N'-diacetylchitobiose + H2O = N-monoacetylchitobiose + acetate ,
3.5.1.108: UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine + H2O → UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine + acetate ,
3.5.1.-: p-aminobenzoyl glutamate + H2O → 4-aminobenzoate + L-glutamate ,
3.5.1.-: pyrazinamide + H2O = ammonium + pyrazine-2-carboxylate ,
3.5.2.3: (S)-dihydroorotate + H2O ↔ N-carbamoyl-L-aspartate + H+ ,
3.5.2.5: (S)-(+)-allantoin + H2O → allantoate + H+ ,
3.5.2.6: a β-lactam[periplasmic space] + H2O[periplasmic space] → a substituted β-amino acid[periplasmic space] ,
3.5.2.-: phenylhydantoin + H2O = phenylureidoacetic acid ,
3.5.3.9: allantoate + 2 H+ + H2O → S-ureidoglycine + ammonium + CO2 ,
3.5.3.11: agmatine + H2O → urea + putrescine ,
3.5.3.23: N2-succinyl-L-arginine + 2 H+ + 2 H2O → 2 ammonium + N2-succinyl-L-ornithine + CO2 ,
3.5.3.26: S-ureidoglycine + H2O → S-ureidoglycolate + ammonium ,
3.5.4.1: cytosine + H+ + H2O → ammonium + uracil ,
3.5.4.2: adenine + H+ + H2O → ammonium + hypoxanthine ,
3.5.4.3: guanine + H+ + H2O → ammonium + xanthine ,
3.5.4.4: adenosine + H+ + H2O → ammonium + inosine ,
3.5.4.4: 2'-deoxyadenosine + H+ + H2O → ammonium + 2'-deoxyinosine ,
3.5.4.5: 2'-deoxycytidine + H+ + H2O → 2'-deoxyuridine + ammonium ,
3.5.4.5: cytidine + H+ + H2O → uridine + ammonium ,
3.5.4.9: a 5,10-methenyltetrahydrofolate + H2O ↔ an N10-formyl-tetrahydrofolate + H+ ,
3.5.4.10: IMP + H2O ↔ 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide ,
3.5.4.13: dCTP + H+ + H2O → ammonium + dUTP ,
3.5.4.16: GTP + H2O → formate + 7,8-dihydroneopterin 3'-triphosphate + H+ ,
3.5.4.19: 1-(5-phospho-β-D-ribosyl)-AMP + H2O → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ,
3.5.4.25: GTP + 3 H2O → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate + 2 H+ ,
3.5.4.26: 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ + H2O → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium ,
3.5.99.6: α-D-glucosamine 6-phosphate + H2O ↔ ammonium + β-D-fructofuranose 6-phosphate ,
3.5.99.10: 2-iminopropanoate + H+ + H2O → pyruvate + ammonium ,
3.5.99.-: 2-iminobutanoate + H+ + H2O → 2-oxobutanoate + ammonium ,
3.5.99.-: (S)-2,3,4,5-tetrahydrodipicolinate + H+ + H2O ↔ L-α-amino-ε-keto-pimelate ,
3.6.1.1: diphosphate + H2O → 2 phosphate + H+ ,
3.6.1.6: CDP + H2O → CMP + phosphate + H+ ,
3.6.1.6: a nucleoside diphosphate + H2O → a nucleoside 5'-monophosphate + phosphate + H+ ,
3.6.1.6: UDP + H2O → UMP + phosphate + H+ ,
3.6.1.7: an acyl phosphate + H2O → a carboxylate + phosphate + H+ ,
3.6.1.8: ATP + H2O → AMP + diphosphate + H+ ,
3.6.1.9: NADH + H2O → NMNH + AMP + 2 H+ ,
3.6.1.11: (polyphosphate)(n) + H2O → (polyphosphate)(n-1) + phosphate ,
3.6.1.15: CTP + H2O → CDP + phosphate + H+ ,
3.6.1.19: ITP + H2O → IMP + diphosphate + H+ ,
3.6.1.19: UTP + H2O → UMP + diphosphate + H+ ,
3.6.1.19: a nucleoside triphosphate + H2O → a nucleoside 5'-monophosphate + diphosphate + H+ ,
3.6.1.19: dATP + H2O → dAMP + diphosphate + H+ ,
3.6.1.19: dTTP + H2O → dTMP + diphosphate + H+ ,
3.6.1.19: dGTP + H2O → dGMP + diphosphate + H+ ,
3.6.1.19/3.6.1.23: dUTP + H2O → dUMP + diphosphate + H+ ,
3.6.1.21: an ADP-sugar + H2O → AMP + an α-D-aldose 1-phosphate ,
3.6.1.22: NAD+ + H2O → β-nicotinamide D-ribonucleotide + AMP + 2 H+ ,
3.6.1.25: PPPi + H2O → phosphate + diphosphate ,
3.6.1.26: a CDP-diacylglycerol + H2O → a 1,2-diacyl-sn-glycerol 3-phosphate + CMP + 2 H+ ,
3.6.1.27: di-trans,octa-cis-undecaprenyl diphosphate + H2O → di-trans,octa-cis-undecaprenyl phosphate + phosphate + H+ ,
3.6.1.31: 1-(5-phospho-β-D-ribosyl)-ATP + H2O → 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate + 2 H+ ,
3.6.1.40: pppGpp + H2O → ppGpp + phosphate + H+ ,
3.6.1.41: 5',5'''-diadenosine tetraphosphate + H2O → 2 ADP + 2 H+ ,
3.6.1.42: GDP + H2O → GMP + phosphate + H+ ,
3.6.1.45: a UDP-sugar[periplasmic space] + H2O[periplasmic space] → UMP[periplasmic space] + an α-D-aldose 1-phosphate[periplasmic space] + 2 H+[periplasmic space] ,
3.6.1.53: ADP-D-ribose + H2O → AMP + D-ribofuranose 5-phosphate + 2 H+ ,
3.6.1.54: UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine + H2O → 2,3-bis[(3R)-3-hydroxymyristoyl]-α-D-glucosaminyl 1-phosphate + UMP + 2 H+ ,
3.6.1.55: 8-oxo-dGTP + H2O → 8-oxo-dGMP + diphosphate + H+ ,
3.6.1.56: 2-hydroxy-dATP + H2O → 2-hydroxy-dAMP + diphosphate + H+ ,
3.6.1.58: 8-oxo-dGDP + H2O → 8-oxo-dGMP + phosphate + H+ ,
3.6.1.63: α-D-ribose-1-methylphosphonate-5-triphosphate + H2O → α-D-ribose-1-methylphosphonate 5-phosphate + diphosphate + H+ ,
3.6.1.65: CTP + H2O → CMP + diphosphate + H+ ,
3.6.1.65: dCTP + H2O → dCMP + diphosphate + H+ ,
3.6.1.66: dITP + H2O → dIMP + diphosphate + H+ ,
3.6.1.66: XTP + H2O → XMP + diphosphate + H+ ,
3.6.1.67: 7,8-dihydroneopterin 3'-triphosphate + H2O → 7,8-dihydroneopterin 3'-phosphate + diphosphate + H+ ,
3.6.1.-: thiamin diphosphate + H2O ↔ thiamin phosphate + phosphate + H+ ,
3.6.1.-: 5-hydroxy-CTP + H2O → 5-hydroxy-CMP + diphosphate + H+ ,
3.6.1.-: 7,8-dihydroneopterin 3'-phosphate + H2O → 7,8-dihydroneopterin + phosphate ,
3.6.1.-: XTP + H2O → XDP + phosphate + H+ ,
3.6.1.-: 8-oxo-GTP + H2O → 8-oxo-GMP + diphosphate + H+ ,
3.6.1.-: 8-oxo-GDP + H2O → 8-oxo-GMP + phosphate + H+ ,
3.6.1.-: ITP + H2O → IDP + phosphate + H+ ,
3.6.3.2: Mg2+[periplasmic space] + ATP + H2O → Mg2+[cytosol] + ADP + phosphate + H+ ,
3.6.3.5: Zn2+[cytosol] + ATP + H2O → Zn2+[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.12: K+[periplasmic space] + ATP + H2O → K+[cytosol] + ADP + phosphate + H+ ,
3.6.3.14: ATP + 3 H+[in] + H2O ↔ ADP + phosphate + 4 H+[out] ,
3.6.3.17: ATP + L-arabinose[periplasmic space] + H2O → ADP + L-arabinose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + D-xylose[periplasmic space] + H2O → ADP + D-xylose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + β-D-ribopyranose[periplasmic space] + H2O → ADP + β-D-ribopyranose[cytosol] + phosphate + H+ ,
3.6.3.17: ATP + β-D-galactose[periplasmic space] + H2O → ADP + β-D-galactose[cytosol] + phosphate + H+ ,
3.6.3.19: maltose[periplasmic space] + ATP + H2O → maltose[cytosol] + ADP + phosphate + H+ ,
3.6.3.20: ATP + sn-glycerol 3-phosphate[periplasmic space] + H2O → ADP + sn-glycerol 3-phosphate[cytosol] + phosphate + H+ ,
3.6.3.21: L-cystine[periplasmic space] + ATP + H2O → L-cystine[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: ATP + L-glutamine[periplasmic space] + H2O → ADP + L-glutamine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-glutamate[periplasmic space] + H2O → ADP + L-glutamate[cytosol] + phosphate + H+ ,
3.6.3.21: L-cysteine[cytosol] + ATP + H2O → L-cysteine[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.21: L-cysteine[periplasmic space] + ATP + H2O → L-cysteine[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: ATP + L-ornithine[periplasmic space] + H2O → ADP + L-ornithine[cytosol] + phosphate + H+ ,
3.6.3.21: ATP + L-histidine[periplasmic space] + H2O → ADP + L-histidine[cytosol] + phosphate + H+ ,
3.6.3.21: L-lysine[periplasmic space] + ATP + H2O → L-lysine[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: ATP + L-aspartate[periplasmic space] + H2O → L-aspartate[cytosol] + ADP + phosphate + H+ ,
3.6.3.21: ATP + L-arginine[periplasmic space] + H2O → ADP + L-arginine[cytosol] + phosphate + H+ ,
3.6.3.24: Ni2+[periplasmic space] + ATP + H2O → Ni2+[cytosol] + ADP + phosphate + H+ ,
3.6.3.25: sulfate[periplasmic space] + ATP + H2O → sulfate[cytosol] + ADP + phosphate + H+ ,
3.6.3.25: ATP + thiosulfate[periplasmic space] + H2O → ADP + thiosulfate[cytosol] + phosphate + H+ ,
3.6.3.27: ATP + phosphate[periplasmic space] + H2O → ADP + 2 phosphate[cytosol] + H+ ,
3.6.3.28: ATP + an alkylphosphonate[periplasmic space] + H2O → ADP + an alkylphosphonate[cytosol] + phosphate + H+ ,
3.6.3.29: ATP + molybdate[periplasmic space] + H2O → ADP + molybdate[cytosol] + phosphate + H+ ,
3.6.3.31: ATP + spermidine[periplasmic space] + H2O → ADP + spermidine[cytosol] + phosphate + H+ ,
3.6.3.31: ATP + putrescine[periplasmic space] + H2O → ADP + putrescine[cytosol] + phosphate + H+ ,
3.6.3.32: a quaternary amine[periplasmic space] + ATP + H2O → a quaternary amine[cytosol] + ADP + phosphate + H+ ,
3.6.3.33: ATP + cob(I)alamin[periplasmic space] + H2O → ADP + cob(I)alamin[cytosol] + phosphate + H+ ,
3.6.3.34: ATP + ferric enterobactin complex[periplasmic space] + H2O → ADP + ferric enterobactin complex[cytosol] + phosphate + H+ ,
3.6.3.34: ATP + ferric dicitrate[periplasmic space] + H2O → ADP + ferric dicitrate[cytosol] + phosphate + H+ ,
3.6.3.34: ATP + a ferric hydroxamate complex[periplasmic space] + H2O → ADP + a ferric hydroxamate complex[cytosol] + phosphate ,
3.6.3.36: taurine[periplasmic space] + ATP + H2O → taurine[cytosol] + ADP + phosphate + H+ ,
3.6.3.39: a lipopolysaccharide[cytosol] + ATP + H2O → a lipopolysaccharide[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.41: ferroheme b[cytosol] + ATP + H2O → ferroheme b[periplasmic space] + ADP + phosphate + H+ ,
3.6.3.53: Ag+[in] + ATP + H2O ↔ Ag+[out] + ADP + phosphate + H+ ,
3.6.3.-: L-idonate[periplasmic space] + H+[periplasmic space] → L-idonate[cytosol] + H+[cytosol] ,
3.6.3.-: α-D-galactofuranose[periplasmic space] + ATP + H2O → α-D-galactofuranose[cytosol] + ADP + phosphate + H+ ,
3.6.3.-: maltotetraose[periplasmic space] + ATP + H2O → ADP + maltotetraose[cytosol] + phosphate + H+ ,
3.6.3.-: maltotriose[periplasmic space] + ATP + H2O → ADP + maltotriose[cytosol] + phosphate + H+ ,
3.6.4.6: ATP + H2O → ADP + phosphate + H+ ,
3.6.4.13: wound RNA + ATP + H2O → an unwound RNA + ADP + phosphate + H+ ,
3.6.5.1/3.6.5.2/3.6.5.3/3.6.5.4/3.6.5.5/3.6.5.6: GTP + H2O → GDP + phosphate + H+ ,
3.7.1.14: (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H2O → (2Z)-2-hydroxypenta-2,4-dienoate + fumarate + H+ ,
3.7.1.14: (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O → (2Z)-2-hydroxypenta-2,4-dienoate + succinate + H+ ,
3.9.1.-: GMP-N-ε-(N-α-acetyl lysine methyl ester) 5'-phosphoramidate + H2O → GMP + N-α-acetyl lysine methyl ester ,
3.13.1.-: 3-sulfinoalanine + H2O = L-alanine + sulfite + H+ ,
4.1.1.8: oxalyl-CoA + H+ = CO2 + formyl-CoA ,
4.1.1.11: L-aspartate + H+ → β-alanine + CO2 ,
4.1.1.15: L-glutamate + H+ → CO2 + 4-aminobutanoate ,
4.1.1.17: L-ornithine + H+ → CO2 + putrescine ,
4.1.1.18: L-lysine + H+ → CO2 + cadaverine ,
4.1.1.19: L-arginine + H+ → CO2 + agmatine ,
4.1.1.20: meso-diaminopimelate + H+ → L-lysine + CO2 ,
4.1.1.23: orotidine 5'-phosphate + H+ → CO2 + UMP ,
4.1.1.31: oxaloacetate + phosphate ↔ phosphoenolpyruvate + hydrogen carbonate ,
4.1.1.36: R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2 ,
4.1.1.37: uroporphyrinogen-III + 4 H+ → 4 CO2 + coproporphyrinogen III ,
4.1.1.41: (R)-methylmalonyl-CoA + H+ → propanoyl-CoA + CO2 ,
4.1.1.47: 2 glyoxylate + H+ → CO2 + tartronate semialdehyde ,
4.1.1.48: 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O ,
4.1.1.49: oxaloacetate + ATP → CO2 + phosphoenolpyruvate + ADP ,
4.1.1.50: S-adenosyl-L-methionine + H+ → CO2 + S-adenosyl 3-(methylthio)propylamine ,
4.1.1.65: an L-1-phosphatidylserine + H+ → an L-1-phosphatidylethanolamine + CO2 ,
4.1.1.85: 3-keto-L-gulonate 6-phosphate + H+ → L-xylulose -5-phosphate + CO2 ,
4.1.1.98: 3-octaprenyl-4-hydroxybenzoate + H+ → 2-octaprenylphenol + CO2 ,
4.1.1.-: a 3-oxoacid + H+ → a methyl ketone + CO2 ,
4.1.2.4: 2-deoxy-D-ribose 5-phosphate ↔ acetaldehyde + D-glyceraldehyde 3-phosphate ,
4.1.2.8: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate ↔ indole + D-glyceraldehyde 3-phosphate ,
4.1.2.13: fructose 1,6-bisphosphate ↔ glycerone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.17: L-fuculose 1-phosphate ↔ (S)-lactaldehyde + glycerone phosphate ,
4.1.2.19: L-rhamnulose 1-phosphate ↔ (S)-lactaldehyde + glycerone phosphate ,
4.1.2.20: 5-dehydro-4-deoxy-D-glucarate ↔ pyruvate + tartronate semialdehyde ,
4.1.2.25: 7,8-dihydroneopterin → glycolaldehyde + 6-hydroxymethyl-7,8-dihydropterin ,
4.1.2.26: L-threo-3-phenylserine = benzaldehyde + glycine ,
4.1.2.28: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate ,
4.1.2.40: D-tagatofuranose 1,6-bisphosphate ↔ glycerone phosphate + D-glyceraldehyde 3-phosphate ,
4.1.2.48: L-threonine → acetaldehyde + glycine ,
4.1.2.48/4.1.2.49: L-allo-threonine ↔ glycine + acetaldehyde ,
4.1.2.50: 7,8-dihydroneopterin 3'-triphosphate + H2O → 6-carboxy-5,6,7,8-tetrahydropterin + PPPi + acetaldehyde + 2 H+ ,
4.1.2.51: 2-dehydro-3-deoxy-D-gluconate = D-glyceraldehyde + pyruvate ,
4.1.2.53: 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde ,
4.1.2.55: 2-dehydro-3-deoxy-D-gluconate 6-phosphate → D-glyceraldehyde 3-phosphate + pyruvate ,
4.1.2.55: 2-dehydro-3-deoxy-D-galactonate 6-phosphate ↔ D-glyceraldehyde 3-phosphate + pyruvate ,
4.1.2.57: 6-deoxy-6-sulfo-D-fructose 1-phosphate → sulfolactaldehyde + glycerone phosphate ,
4.1.2.-: glycerone phosphate + D-erythrose 4-phosphate ← D-sedoheptulose-1,7-bisphosphate ,
4.1.2.-: 4-hydroxy-L-threonine ↔ glycolaldehyde + glycine ,
4.1.2.-: β-D-fructofuranose 6-phosphate ↔ dihydroxyacetone + D-glyceraldehyde 3-phosphate ,
4.1.2.-: DL-allothreonine ↔ acetaldehyde + glycine ,
4.1.3.1: D-threo-isocitrate ↔ glyoxylate + succinate ,
4.1.3.3: N-acetyl-β-neuraminate = N-acetyl-β-D-mannosamine + pyruvate ,
4.1.3.3: N-acetylneuraminate ↔ N-acetyl-D-mannosamine + pyruvate ,
4.1.3.6: citrate → acetate + oxaloacetate ,
4.1.3.27: chorismate + L-glutamine → anthranilate + pyruvate + L-glutamate + H+ ,
4.1.3.30: (2R,3S)-2-methylisocitrate ↔ succinate + pyruvate ,
4.1.3.36: 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + H+ → 1,4-dihydroxy-2-naphthoyl-CoA + H2O ,
4.1.3.38: 4-amino-4-deoxychorismate ↔ 4-aminobenzoate + pyruvate + H+ ,
4.1.3.39: 4-hydroxy-2-oxopentanoate ↔ acetaldehyde + pyruvate ,
4.1.3.40: chorismate → 4-hydroxybenzoate + pyruvate ,
4.1.3.42: (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate ,
4.1.99.1: L-tryptophan + H2O = ammonium + indole + pyruvate ,
4.1.99.12: D-ribulose 5-phosphate → 1-deoxy-L-glycero-tetrulose 4-phosphate + formate + H+ ,
4.1.99.17: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + carbon monoxide + 3 H+ ,
4.1.99.18: GTP → cyclic pyranopterin phosphate + diphosphate ,
4.1.99.19: L-tyrosine + S-adenosyl-L-methionine + NADPH → 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP+ + H+ ,
4.2.1.1: hydrogen carbonate + H+ ↔ CO2 + H2O ,
4.2.1.2: (S)-malate ↔ fumarate + H2O ,
4.2.1.7: D-altronate → 2-dehydro-3-deoxy-D-gluconate + H2O ,
4.2.1.8: D-mannonate → 2-dehydro-3-deoxy-D-gluconate + H2O ,
4.2.1.9: (2R)-2,3-dihydroxy-3-methylbutanoate → 3-methyl-2-oxobutanoate + H2O ,
4.2.1.9: (R)-2,3-dihydroxy-3-methylpentanoate → (S)-3-methyl-2-oxopentanoate + H2O ,
4.2.1.10: 3-dehydroquinate ↔ 3-dehydroshikimate + H2O ,
4.2.1.11: 2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O ,
4.2.1.12: D-gluconate 6-phosphate → 2-dehydro-3-deoxy-D-gluconate 6-phosphate + H2O ,
4.2.1.17: a (3S)-3-hydroxyacyl-CoA ← a trans-2-enoyl-CoA + H2O ,
4.2.1.17: 3-hydroxyadipyl-CoA ↔ 2,3-didehydroadipyl-CoA + H2O ,
4.2.1.19: D-erythro-imidazole-glycerol-phosphate → imidazole acetol-phosphate + H2O ,
4.2.1.20: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine → L-tryptophan + D-glyceraldehyde 3-phosphate + H2O ,
4.2.1.24: 2 5-aminolevulinate → porphobilinogen + H+ + 2 H2O ,
4.2.1.32: L-tartrate ↔ oxaloacetate + H2O ,
4.2.1.40: D-glucarate → 5-dehydro-4-deoxy-D-glucarate + H2O ,
4.2.1.42: galactarate → 5-dehydro-4-deoxy-D-glucarate + H2O ,
4.2.1.46: dTDP-α-D-glucose → dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O ,
4.2.1.47: GDP-α-D-mannose → GDP-4-dehydro-6-deoxy-α-D-mannose + H2O ,
4.2.1.51: prephenate + H+ → 2-oxo-3-phenylpropanoate + CO2 + H2O ,
4.2.1.55: (R)-3-hydroxybutanoyl-CoA = crotonyl-CoA + H2O ,
4.2.1.70: D-ribofuranose 5-phosphate + uracil ↔ pseudouridine 5'-phosphate + H2O ,
4.2.1.75: preuroporphyrinogen → uroporphyrinogen-III + H2O ,
4.2.1.79: (2S,3S)-2-methylcitrate → cis-2-methylaconitate + H2O ,
4.2.1.80: 2-oxopent-4-enoate + H2O → 4-hydroxy-2-oxopentanoate ,
4.2.1.81: D-tartrate = oxaloacetate + H2O ,
4.2.1.82: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H2O ,
4.2.1.90: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H2O ,
4.2.1.99: (2R,3S)-2-methylisocitrate ↔ cis-2-methylaconitate + H2O ,
4.2.1.104: cyanate + hydrogen carbonate + H+ → carbamate + CO2 ,
4.2.1.113: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate → 2-succinylbenzoate + H2O ,
4.2.1.122: indole + L-serine → L-tryptophan + H2O ,
4.2.1.126: N-acetyl-β-muramate 6-phosphate + H2O ↔ N-acetyl-D-glucosamine 6-phosphate + (R)-lactate ,
4.2.1.130: (R)-lactate + H+ ← methylglyoxal + H2O ,
4.2.1.136: (S)-NADPHX + ADP → AMP + NADPH + phosphate + H+ ,
4.2.1.136: ADP + (S)-NADHX → AMP + NADH + phosphate + H+ ,
4.2.1.140: D-galactonate → 2-dehydro-3-deoxy-D-galactonate + H2O ,
4.2.1.149: L-carnitinyl-CoA → crotonobetainyl-CoA + H2O ,
4.2.2.-: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide ,
4.2.3.1: O-phospho-L-homoserine + H2O → L-threonine + phosphate ,
4.2.3.3: glycerone phosphate → methylglyoxal + phosphate ,
4.2.3.4: 3-deoxy-D-arabino-heptulosonate-7-phosphate → 3-dehydroquinate + phosphate ,
4.2.3.5: 5-enolpyruvyl-shikimate 3-phosphate → chorismate + phosphate ,
4.2.99.20: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate → (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate ,
4.3.1.1: L-aspartate ↔ ammonium + fumarate ,
4.3.1.7: ethanolamine → ammonium + acetaldehyde ,
4.3.1.15: 2,3-diaminopropanoate + H+ + H2O → 2 ammonium + pyruvate + H+ ,
4.3.1.17: L-serine → pyruvate + ammonium ,
4.3.1.18: D-serine = pyruvate + ammonium ,
4.3.1.19: L-threonine → 2-oxobutanoate + ammonium ,
4.3.1.-: O-succinyl-L-homoserine + H2O → 2-oxobutanoate + succinate + ammonium + H+ ,
4.3.2.1: L-arginino-succinate ↔ L-arginine + fumarate ,
4.3.2.2: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole → fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ,
4.3.2.2: adenylo-succinate → fumarate + AMP ,
4.3.2.3: S-ureidoglycolate → urea + glyoxylate ,
4.3.3.7: pyruvate + L-aspartate-semialdehyde → (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+ ,
4.3.99.3: 6-carboxy-5,6,7,8-tetrahydropterin + H+ → 7-carboxy-7-deazaguanine + ammonium ,
4.4.1.1/4.4.1.28: L-cysteine + H2O → pyruvate + ammonium + hydrogen sulfide ,
4.4.1.5: (R)-S-lactoylglutathione ← methylglyoxal + glutathione ,
4.4.1.8: L-cystathionine + H2O → ammonium + pyruvate + L-homocysteine ,
4.4.1.15: D-cysteine + H2O → ammonium + pyruvate + hydrogen sulfide ,
4.4.1.16: L-selenocysteine + an reduced unknown electron acceptor = L-alanine + selenide + an oxidized unknown electron acceptor + 2 H+ ,
4.4.1.21: S-ribosyl-L-homocysteine → L-homocysteine + autoinducer 2 ,
4.4.1.22: S-hydroxymethylglutathione → formaldehyde + glutathione ,
4.5.1.2: 3-chloro-D-alanine + thioglycolate = S-carboxymethyl-D-cysteine + chloride + H+ ,
4.6.1.1: ATP → cyclic-AMP + diphosphate ,
4.6.1.2: GTP ↔ cyclic-GMP + diphosphate ,
4.6.1.12: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol → CMP + 2-C-methyl-D-erythritol-2,4-cyclodiphosphate ,
4.7.1.1: α-D-ribose-1-methylphosphonate 5-phosphate → 5-phospho-α-D-ribose 1,2-cyclic phosphate + methane ,
4.99.1.1: Fe2+ + protoporphyrin IX ← ferroheme b + 2 H+ ,
4.99.1.4: sirohydrochlorin + Fe2+ ↔ siroheme + 2 H+ ,
5.1.1.1: L-alanine ↔ D-alanine ,
5.1.1.3: L-glutamate ↔ D-glutamate ,
5.1.1.7: L,L-diaminopimelate ↔ meso-diaminopimelate ,
5.1.1.20: L-alanyl-D-glutamate ↔ L-alanyl-L-glutamate ,
5.1.2.3: a (3R)-3-hydroxyacyl-CoA ↔ a (3S)-3-hydroxyacyl-CoA ,
5.1.2.-: L-idarate ↔ D-glucarate ,
5.1.3.1: D-ribulose 5-phosphate ↔ D-xylulose 5-phosphate ,
5.1.3.2: UDP-α-D-glucose ↔ UDP-α-D-galactose ,
5.1.3.3: α-D-glucose ↔ β-D-glucopyranose ,
5.1.3.3: β-D-galactose ↔ α-D-galactose ,
5.1.3.4: L-ribulose 5-phosphate ↔ D-xylulose 5-phosphate ,
5.1.3.9: N-acetyl-D-mannosamine 6-phosphate ↔ N-acetyl-D-glucosamine 6-phosphate ,
5.1.3.13: dTDP-4-dehydro-6-deoxy-α-D-glucopyranose → dTDP-4-dehydro-β-L-rhamnose ,
5.1.3.14: UDP-N-acetyl-α-D-glucosamine ↔ UDP-N-acetyl-α-D-mannosamine ,
5.1.3.15: α-D-glucose 6-phosphate ↔ β-D-glucose 6-phosphate ,
5.1.3.20: ADP-D-glycero-β-D-manno-heptose → ADP-L-glycero-β-D-manno-heptose ,
5.1.3.22: L-ribulose 5-phosphate ← L-xylulose -5-phosphate ,
5.1.3.24: N-acetyl-α-neuraminate ↔ N-acetyl-β-neuraminate ,
5.1.3.29: α-L-fucopyranose ↔ β-L-fucopyranose ,
5.1.3.32: α-L-rhamnopyranose → β-L-rhamnopyranose ,
5.1.3.-: β-L-lyxopyranose ↔ L-xylulose ,
5.1.3.-: α-D-mannose 6-phosphate ↔ β-D-mannose 6-phosphate ,
5.1.3.-: D-allulose 6-phosphate → β-D-fructofuranose 6-phosphate ,
5.1.99.1: (R)-methylmalonyl-CoA ↔ (S)-methylmalonyl-CoA ,
5.1.99.6: (R)-NADHX = (S)-NADHX ,
5.1.99.6: (R)-NADPHX = (S)-NADPHX ,
5.1.99.-: 7,8-dihydroneopterin 3'-triphosphate ↔ 7,8-dihydromonapterin triphosphate ,
5.2.1.8: a [protein]-L-proline (ω = 180) = a [protein]-L-proline (ω = 0) ,
5.3.1.1: D-glyceraldehyde 3-phosphate ↔ glycerone phosphate ,
5.3.1.3: D-arabinopyranose ↔ D-ribulose ,
5.3.1.4: L-arabinopyranose ↔ L-ribulose ,
5.3.1.5: a D-xylopyranose ↔ D-xylulose ,
5.3.1.6: D-ribose 5-phosphate ↔ D-ribulose 5-phosphate ,
5.3.1.7: aldehydo-D-mannose ↔ keto-D-fructose ,
5.3.1.8: D-mannopyranose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.9: β-D-glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
5.3.1.12: aldehydo-D-galacturonate ↔ D-tagaturonate ,
5.3.1.12: aldehydo-D-glucuronate ↔ D-fructuronate ,
5.3.1.13: D-arabinose 5-phosphate ↔ D-ribulose 5-phosphate ,
5.3.1.14: β-L-rhamnopyranose ↔ keto-L-rhamnulose ,
5.3.1.16: 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide → phosphoribulosylformimino-AICAR-P ,
5.3.1.17: 5-dehydro-4-deoxy-D-glucuronate ↔ 3-deoxy-D-glycero-2,5-hexodiulosonate ,
5.3.1.22: hydroxypyruvate ↔ tartronate semialdehyde ,
5.3.1.24: N-(5-phosphoribosyl)-anthranilate → 1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate ,
5.3.1.25: α-L-fucopyranose ↔ L-fuculose ,
5.3.1.28: D-sedoheptulose 7-phosphate → D-glycero-D-manno-heptose 7-phosphate ,
5.3.1.31: sulfoquinovose → 6-deoxy-6-sulfo-D-fructose ,
5.3.1.32: (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione → 3-hydroxy-5-phosphonooxypentane-2,4-dione ,
5.3.1.-: aldehydo-D-allose 6-phosphate ↔ D-allulose 6-phosphate ,
5.3.2.1: 2-oxo-3-phenylpropanoate → enol-phenylpyruvate ,
5.3.2.2: oxaloacetate = enol-oxaloacetate ,
5.3.2.8: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate ↔ (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
5.3.3.2: isopentenyl diphosphate ↔ dimethylallyl diphosphate ,
5.3.3.7: trans-aconitate = cis-aconitate ,
5.3.3.8: 3-cis-dodecenoyl-CoA = trans-dodec-2-enoyl-CoA ,
5.3.3.8: a cis-3-enoyl-CoA ↔ a trans-2-enoyl-CoA ,
5.3.3.14: a (2E)-dec-2-enoyl-[acp] ↔ a (3Z)-dec-3-enoyl-[acp] ,
5.3.3.18: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA ↔ 2-oxepin-2(3H)-ylideneacetyl-CoA ,
5.3.3.-: 2-trans,5-cis-tetradecadienoyl-CoA ↔ 3-trans,5-cis-tetradecadienoyl-CoA ,
5.4.1.-: α-lactose = allolactose ,
5.4.2.5: α-D-glucopyranose 1-phosphate ↔ α-D-glucose 6-phosphate ,
5.4.2.6: β-D-glucose 1-phosphate = β-D-glucose 6-phosphate ,
5.4.2.7: 2-deoxy-α-D-ribose 1-phosphate ↔ 2-deoxy-D-ribose 5-phosphate ,
5.4.2.7: α-D-ribose-1-phosphate ↔ D-ribose 5-phosphate ,
5.4.2.8: α-D-mannose 1-phosphate ↔ D-mannopyranose 6-phosphate ,
5.4.2.10: D-glucosamine 6-phosphate ↔ D-glucosamine 1-phosphate ,
5.4.2.11: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.2.12: 2-phospho-D-glycerate ↔ 3-phospho-D-glycerate ,
5.4.3.8: (S)-4-amino-5-oxopentanoate → 5-aminolevulinate ,
5.4.3.-: L-lysine = (R)-β-lysine ,
5.4.4.2: chorismate ↔ isochorismate ,
5.4.99.2: (R)-methylmalonyl-CoA ↔ succinyl-CoA ,
5.4.99.5: chorismate → prephenate ,
5.4.99.9: UDP-α-D-galactose ↔ UDP-α-D-galactofuranose ,
5.4.99.18: N5-carboxyaminoimidazole ribonucleotide → 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate ,
5.4.99.19: a uridine516 in 16S rRNA → a 16S rRNA pseudouridine516 ,
5.4.99.20: uridine2457 in 23S rRNA → a pseudouridine2457 in 23S rRNA ,
5.4.99.21: a uridine2604 in 23S rRNA → a pseudouridine2604 in 23S rRNA ,
5.4.99.22: uridine2605 in 23S rRNA → a pseudouridine2605 in 23S rRNA ,
5.4.99.23: a 23S rRNA uridine1911/1915/1917 → a pseudouridine1911/1915/1917 in 23S rRNA ,
5.4.99.24: uridine955/2504/2580 in 23S rRNA → a pseudouridine955/2504/2580 in 23S rRNA ,
5.4.99.25: a uridine55 in tRNA = a tRNA pseudouridine55 ,
5.4.99.26: a uridine65 in tRNA = a tRNA pseudouridine65 ,
5.4.99.27: a uridine13 in tRNA = a pseudouridine13 in tRNA ,
5.4.99.28: a uridine32 in tRNA → a pseudouridine32 in tRNA ,
5.4.99.29: uridine746 in 23S rRNA → a pseudouridine746 in 23S rRNA ,
5.4.99.62: β-D-ribopyranose ↔ β-D-ribofuranose ,
5.99.1.2: a negatively supercoiled DNA = a relaxed DNA ,
5.99.1.3: a double stranded DNA + ATP = a negatively supercoiled DNA + ADP + phosphate ,
6.2.1.1: acetate + ATP + coenzyme A → acetyl-CoA + AMP + diphosphate ,
6.2.1.3: a 2,3,4-saturated fatty acid + ATP + coenzyme A → a 2,3,4-saturated fatty acyl CoA + AMP + diphosphate ,
6.2.1.5: succinate + ATP + coenzyme A ↔ succinyl-CoA + ADP + phosphate ,
6.2.1.17: propanoate + ATP + coenzyme A → propanoyl-CoA + AMP + diphosphate ,
6.2.1.26: ATP + 2-succinylbenzoate + coenzyme A → AMP + 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + diphosphate ,
6.2.1.30: phenylacetate + ATP + coenzyme A → phenylacetyl-CoA + AMP + diphosphate ,
6.2.1.-: L-carnitine + ATP + coenzyme A → L-carnitinyl-CoA + AMP + diphosphate ,
6.3.1.1: L-aspartate + ammonium + ATP → L-asparagine + AMP + diphosphate + H+ ,
6.3.1.2: ammonium + L-glutamate + ATP → L-glutamine + ADP + phosphate + H+ ,
6.3.1.5: ammonium + ATP + nicotinate adenine dinucleotide → AMP + NAD+ + diphosphate + H+ ,
6.3.1.9: spermidine + glutathione + ATP → glutathionylspermidine + ADP + phosphate + H+ ,
6.3.1.11: putrescine + L-glutamate + ATP → γ-glutamyl-L-putrescine + ADP + phosphate + H+ ,
6.3.2.1: β-alanine + (R)-pantoate + ATP → (R)-pantothenate + AMP + diphosphate + H+ ,
6.3.2.2: L-cysteine + L-glutamate + ATP → γ-L-glutamyl-L-cysteine + ADP + phosphate + H+ ,
6.3.2.3: glycine + γ-L-glutamyl-L-cysteine + ATP → glutathione + ADP + phosphate + H+ ,
6.3.2.4: 2 D-alanine + ATP → D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.5: (R)-4'-phosphopantothenate + L-cysteine + CTP → CMP + R-4'-phosphopantothenoyl-L-cysteine + diphosphate + H+ ,
6.3.2.6: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate → ADP + 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole + phosphate + H+ ,
6.3.2.8: L-alanine + UDP-N-acetyl-α-D-muramate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanine + ADP + phosphate + H+ ,
6.3.2.9: D-glutamate + UDP-N-acetyl-α-D-muramoyl-L-alanine + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + ADP + phosphate + H+ ,
6.3.2.10: D-alanyl-D-alanine + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.12: L-glutamate + 7,8-dihydropteroate + ATP → ADP + 7,8-dihydrofolate monoglutamate + phosphate + H+ ,
6.3.2.13: meso-diaminopimelate + UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.14: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate → 6 AMP + enterobactin + 6 diphosphate + 3 H+ ,
6.3.2.17: methylene-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → methylene-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.17: 10-formyl-tetrahydropteroyl-[γ-Glu](n) + L-glutamate + ATP → 10-formyl-tetrahydropteroyl-[γ-Glu](n+1) + ADP + phosphate ,
6.3.2.45: UDP-N-acetyl-α-D-muramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + ATP → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + ADP + phosphate + H+ ,
6.3.2.45: UDP-N-acetyl-α-D-muramate + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + ADP + phosphate + H+ ,
6.3.2.-: a [protein chain elongation factor EF-P]-L-lysine34 + (R)-β-lysine + ATP → [a protein chain elongation factor EF-P]-β-L-lysyl-L-lysine34 + AMP + diphosphate + H+ ,
6.3.2.-: a [protein] C-terminal L-glutamate + L-glutamate + ATP → a [protein] with C-terminal α-L-glutamate-α-L-glutamate + ADP + phosphate + H+ ,
6.3.3.1: ATP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine → ADP + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + phosphate + H+ ,
6.3.3.2: an N5-formyl-tetrahydrofolate + ATP → a 5,10-methenyltetrahydrofolate + ADP + phosphate ,
6.3.3.3: CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+ ,
6.3.4.2: ATP + UTP + L-glutamine + H2O → ADP + CTP + L-glutamate + phosphate + 2 H+ ,
6.3.4.4: L-aspartate + IMP + GTP → adenylo-succinate + GDP + phosphate + 2 H+ ,
6.3.4.5: L-aspartate + L-citrulline + ATP → L-arginino-succinate + AMP + diphosphate + H+ ,
6.3.4.13: ATP + 5-phospho-β-D-ribosylamine + glycine → ADP + N1-(5-phospho-β-D-ribosyl)glycinamide + phosphate + H+ ,
6.3.4.18: 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + hydrogen carbonate → N5-carboxyaminoimidazole ribonucleotide + ADP + phosphate + 2 H+ ,
6.3.4.20: 7-carboxy-7-deazaguanine + ammonium + ATP → preQ0 + ADP + phosphate + H+ + H2O ,
6.3.4.21: nicotinate + 5-phospho-α-D-ribose 1-diphosphate + ATP + H2O → β-nicotinate D-ribonucleotide + ADP + diphosphate + phosphate ,
6.3.5.1: ATP + nicotinate adenine dinucleotide + L-glutamine + H2O → AMP + L-glutamate + NAD+ + diphosphate + H+ ,
6.3.5.2: L-glutamine + XMP + ATP + H2O → L-glutamate + GMP + AMP + diphosphate + 2 H+ ,
6.3.5.3: ATP + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + H2O → ADP + 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + L-glutamate + phosphate + H+ ,
6.3.5.4: L-glutamine + L-aspartate + ATP + H2O → L-glutamate + L-asparagine + AMP + diphosphate + H+ ,
6.3.5.5: 2 ATP + L-glutamine + hydrogen carbonate + H2O → carbamoyl-phosphate + L-glutamate + 2 ADP + phosphate + 2 H+ ,
6.3.5.5: 2 ATP + hydrogen carbonate + ammonium → 2 ADP + carbamoyl-phosphate + phosphate + 2 H+ ,
6.4.1.2: ATP + acetyl-CoA + hydrogen carbonate → malonyl-CoA + ADP + phosphate + H+ ,
6.4.1.3: ATP + hydrogen carbonate + propanoyl-CoA → ADP + (S)-methylmalonyl-CoA + phosphate + H+ ,
6.5.1.6: (deoxynucleotides)(m) + (deoxynucleotides)(n) + NAD+ → (deoxynucleotides)(n+m) + β-nicotinamide D-ribonucleotide + AMP ,
6.5.1.-: a 5' half-tRNA molecule with a 2',3' cyclic phosphate on its 3' end + a 3' half-tRNA molecule with a hydroxyl on its 5' end ↔ a ligated tRNA with a 2'-5' linkage ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
2-aminoprop-2-enoate + H+ + H2O → pyruvate + ammonium ,
2 L-ascorbate + an oxidized unknown electron acceptor + 2 H+ → 2 monodehydroascorbate radical + an reduced unknown electron acceptor ,
ammonia + H+ ↔ ammonium ,
NADH + H2O → (R)-NADHX ,
aldehydo-L-galactonate + NAD+ → D-tagaturonate + NADH + H+ ,
an [L-cysteine desulfurase] L-cysteine persulfide + a ThiI sulfur-carrier protein → an [L-cysteine desulfurase]-L-cysteine + an S-sulfanyl-[ThiI sulfur-carrier protein] ,
4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + H2O → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + formate ,
aldehydo-D-xylose ↔ a D-xylopyranose ,
D-glucopyranuronate ↔ aldehydo-D-glucuronate ,
β-D-glucopyranose[periplasmic space] ↔ D-glucose[periplasmic space] ,
α-D-ribofuranose ↔ β-D-ribofuranose ,
an E. coli osmoregulated periplasmic glucan (OPG)[periplasmic space] + an L-1-phosphatidylethanolamine[periplasmic space] → an E. coli osmoregulated periplasmic glucan with phosphotidylethanolamine substituent[periplasmic space] + a 1,2-diacyl-sn-glycerol[periplasmic space] ,
L-tryptophan → indole + 2-aminoprop-2-enoate + H+ ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
a 5,10-methenyltetrahydrofolate + H2O = an N5-formyl-tetrahydrofolate + H+ ,
D-gluconate + NAD+ ↔ 5-dehydro-D-gluconate + NADH + H+ ,
(S)-1-pyrroline-5-carboxylate + NAD+ + 2 H2O → L-glutamate + NADH + H+ ,
formate + H+ → CO2 + H2 ,
D-fructosyl-L-lysine + ATP → fructoselysine 6-phosphate + ADP + H+ ,
GDP-α-D-mannose + H2O → GMP + α-D-mannose 1-phosphate + 2 H+ ,
L-dehydro-ascorbate + H2O → dehydroascorbate (bicyclic form) ,
(2Z)-2-hydroxypenta-2,4-dienoate ↔ 2-oxopent-4-enoate ,
preuroporphyrinogen → uroporphyrinogen-I + H2O ,
poly-β-1,6-N-acetyl-D-glucosamine + H2O = partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine + acetate + H+ ,
D-galactopyranuronate ↔ aldehydo-D-galacturonate ,
2 Fe2+ + hydrogen peroxide + 2 H2O → 2 [FeO(OH)] monomer + 4 H+ ,
(2E)-2-hydroxypenta-2,4-dienoate ↔ 2-oxopent-4-enoate ,
a 5-hydroxyuridine34 in tRNA + carboxy-S-adenosyl-L-methionine → a 5-(carboxymethoxy)uridine34 in tRNA + S-adenosyl-L-homocysteine + H+ ,
phenylacetyl-CoA + H2O = phenylacetate + coenzyme A + H+ ,
α-D-ribose-1-phosphate + ATP → α-D-ribose 1,5-bisphosphate + ADP + H+ ,
autoinducer 2 → (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
2-(α-hydroxyethyl)thiamine diphosphate + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine = a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine + thiamin diphosphate ,
2,3-dioxo-L-gulonate → 2-carboxy-L-xylonolactone ,
a nucleoside 5'-monophosphate[periplasmic space] + H2O[periplasmic space] → a nucleoside[periplasmic space] + phosphate[periplasmic space] ,
aldehydo-L-arabinose ↔ L-arabinopyranose ,
aminoacrylate + H+ + H2O → 3-oxopropanoate + ammonium ,
L-threonine → (2Z)-2-aminobut-2-enoate + H2O + H+ ,
curcumin + NADPH + H+ → dihydrocurcumin + NADP+ ,
MoO2-molybdopterin cofactor + molybdopterin + H+ = bis(molybdenum cofactor) + H2O ,
an O-acetyl-ADP-ribose + H2O = ADP-D-ribose + acetate ,
(S)-propane-1,2-diol + NAD+ ↔ acetol + NADH + H+ ,
L-serine + ATP + H+ ↔ L-seryl-adenylate + diphosphate ,
UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + H2O → D-alanine + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate ,
dGTP + 2 hydroxyl radical → 8-oxo-dGTP + H2O ,
(2R,3S)-3-isopropylmalate + NAD+ ↔ (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ ,
2 Fe2+ + 2 oxygen → 2 superoxide + 2 Fe3+ ,
carbamate + 2 H+ → ammonium + CO2 ,
cis-aconitate + H2O ↔ D-threo-isocitrate ,
keto-L-sorbose ↔ L-sorbopyranose ,
(Z)-3-peroxyaminoacrylate + an reduced unknown electron acceptor → aminoacrylate + an oxidized unknown electron acceptor + H2O + H+ ,
L-serine → 2-aminoprop-2-enoate + H+ + H2O ,
D-sedoheptulose 7-phosphate + ATP → D-sedoheptulose-1,7-bisphosphate + ADP + H+ ,
D-ribulose + ATP → D-ribulose 1-phosphate + ADP + H+ ,
CTP + 2 hydroxyl radical → 5-hydroxy-CTP + H2O ,
D-ribulose 5-phosphate + NADH + H+ → 1-deoxy-D-xylulose 5-phosphate + NAD+ + H2O ,
3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + coenzyme A + H+ ,
β-D-ribofuranose ↔ aldehydo-D-ribose ,
ATP + UTP + ammonium → ADP + CTP + phosphate + 2 H+ ,
L-cystathionine → 2-aminoprop-2-enoate + L-homocysteine + H+ ,
β-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
5'-deoxyadenosine + H2O → 5-deoxy-D-ribose + adenine ,
L-methionine + hydrogen peroxide → L-methionine S-oxide + H2O ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
a 2-thiouridine34 in tRNA + a 5,10-methylene-tetrahydrofolate + ammonium + GTP + H2O → a 5-aminomethyl-2-thiouridine in tRNA + a 7,8-dihydrofolate + GDP + phosphate ,
D-fructosyl-L-lysine ↔ psicoselysine ,
NADH + H2O → (S)-NADHX ,
a lipopolysaccharide + dTDP-β-L-rhamnose = a rhamnosyl lipopolysaccharide + dTDP ,
2-iminoacetate + H+ + H2O → glyoxylate + ammonium ,
histidinol + NAD+ → histidinal + NADH + H+ ,
an L-1-phosphatidylethanolamine[periplasmic space] + lipid A-core[periplasmic space] → a 1,2-diacyl-sn-glycerol[periplasmic space] + lipid A-core-1-pyrophosphoethanolamine[periplasmic space] ,
aldehydo-D-mannose → β-D-mannose ,
carbamoyl-phosphate + ATP + H2O = O-carbamoyladenylate + diphosphate + phosphate ,
aldehydo-D-ribose ↔ D-ribopyranose ,
O-succinyl-L-homoserine → succinate + (2Z)-2-aminobut-2-enoate + 2 H+ ,
3-phospho-hydroxypyruvate + H2O → hydroxypyruvate + phosphate ,
a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing) → a mature peptidoglycan with L,D cross-links (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
betaine aldehyde hydrate ↔ betaine aldehyde + H2O ,
sulfite + H+ ↔ hydrogen sulfite ,
2-isopropylmaleate + H2O → (2R,3S)-3-isopropylmalate ,
L-alanyl-γ-D-glutamyl-meso-diaminopimelate + H2O → L-alanyl-D-glutamate + meso-diaminopimelate ,
2-oxoglutarate + coenzyme A + NAD+ → succinyl-CoA + CO2 + NADH ,
arbutin[periplasmic space] + HPr-Phis15 → arbutin-6-phosphate[cytosol] + HPr ,
dehydroascorbate (bicyclic form) → 2,3-dioxo-L-gulonate + H+ ,
4-hydroxy-2-oxopentanoate → (2Z)-2,4-dihydroxypent-2-enoate ,
D-alanine + pyridoxal 5'-phosphate ↔ pyruvate + pyridoxamine 5'-phosphate ,
(R)-3-hydroxybutanoyl-CoA + H2O → (R)-3-hydroxybutanoate + coenzyme A + H+ ,
UDP-N-acetyl-α-D-glucosamine = poly-β-1,6-N-acetyl-D-glucosamine + UDP ,
D-allopyranose ↔ aldehydo-D-allose ,
α-D-ribose 5-phosphate → keto-D-ribose 5-phosphate ,
2 Fe2+ + oxygen + 4 H2O → 2 [FeO(OH)] monomer + hydrogen peroxide + 4 H+ ,
syringaldazine + oxygen → oxidized syringaldazine + 2 H2O ,
prephenate + S-adenosyl-L-methionine → 2-oxo-3-phenylpropanoate + carboxy-S-adenosyl-L-methionine + H2O ,
2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA + H2O = 2-hydroxycyclohepta-1,4,6-triene-1-carboxylate + coenzyme A ,
pyruvate + acetaldehyde + H+ → acetoin + CO2 ,
autoinducer 2 → (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one ,
β-D-galactofuranose[periplasmic space] + ATP + H2O → β-D-galactofuranose[cytosol] + ADP + phosphate + H+ ,
a supercoiled duplex DNA + ATP = a single stranded DNA + ADP + phosphate ,
2 L-dehydro-ascorbate + oxygen → 2 cyclic-2,3-O-oxalyl-L-threonate + 2 H+ ,
GDP-L-fucose + UDP-D-glucose + UDP-α-D-glucuronate + UDP-α-D-galactose = colanic acid ,
aldehydo-D-galactose → D-galactopyranose ,
(S)-lactate + an oxidized unknown electron acceptor → pyruvate + an reduced unknown electron acceptor ,
D-arabinofuranose ↔ D-arabinopyranose ,
3-ureidoacrylate + H2O → carbamate + aminoacrylate + H+ ,
(2Z)-2-aminobut-2-enoate → 2-iminobutanoate ,
3-mercaptopyruvate → pyruvate + hydrogen sulfide ,
an L-1-phosphatidyl-glycerol + an L-1-phosphatidylethanolamine → a cardiolipin + ethanolamine ,
pyridoxamine 5'-phosphate + a deaminated amino group donor ↔ pyridoxal 5'-phosphate + an aminated amino group donor ,
N6-L-threonylcarbamoyladenine37 in tRNA + ATP → cyclic N6-L-threonylcarbamoyladenosine 37 in tRNA + ADP + phosphate ,
(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
GTP + 2 hydroxyl radical → 8-oxo-GTP + H2O ,
2-amino-3-oxobutanoate + H+ → aminoacetone + CO2 ,
α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IVA + ADP-L-glycero-β-D-manno-heptose = heptosyl-Kdo2-lipid IVA + ADP + H+ ,
hydrogen peroxide + Fe2+ → hydroxyl radical + Fe3+ + OH- ,
cyclic-2,3-O-oxalyl-L-threonate → cyclic- 3,4-O-oxalyl-L-threonate ,
H+ + OH- ↔ H2O ,
citrate ↔ cis-aconitate + H2O ,
keto-D-fructose → β-D-fructofuranose ,
D-tagatofuranose ↔ keto-D-tagatose ,
(Z)-3-ureidoacrylate peracid + H2O → carbamate + (Z)-3-peroxyaminoacrylate + H+ ,
2-aminoprop-2-enoate → 2-iminopropanoate ,
isoguanine + H+ + H2O → xanthine + ammonium ,
2 monodehydroascorbate radical → L-ascorbate + L-dehydro-ascorbate + H+ ,
(2S)-2-isopropyl-3-oxosuccinate + H+ → 4-methyl-2-oxopentanoate + CO2 ,
m7GTP + H2O → N7-methylguanosine 5'-phosphate + diphosphate + H+ ,
D-threo-isocitrate + NADP+ = oxalosuccinate + NADPH + H+ ,
putrescine + 2-oxoglutarate → 4-aminobutanal + L-glutamate ,
glucosamine 1,6-diphosphate + a phosphoglucosamine mutase = D-glucosamine 1-phosphate + a phosphorylated phosphoglucosamine mutase ,
4-(2-aminophenyl)-2,4-dioxobutanoate → kynurenate + H2O + H+ ,
γ-glutamyl-L-putrescine + H2O + oxygen → 4-(γ-glutamylamino)butanal + hydrogen peroxide + ammonium ,
dATP + 2 hydroxyl radical → 2-hydroxy-dATP + H2O ,
2-thio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-methionine → 2-methylthio-N6-dimethylallyladenosine37 in tRNA + S-adenosyl-L-homocysteine + H+ ,
aldehydo-L-fucose ↔ L-fucopyranose ,
L-cysteine → 2-aminoprop-2-enoate + hydrogen sulfide + H+ ,
α-D-ribose 5-phosphate → β-D-ribose 5-phosphate ,
bromoacetate + glutathione = glutathione-S-acetate + bromide + H+ ,
3-oxo-L-alanine + H+ → 2-aminoacetaldehyde + CO2 ,
3-hydroxy-5-phosphonooxypentane-2,4-dione + H2O = 3,4,4-trihydroxy-5-phosphonooxypentan-2-one ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide[periplasmic space] + a peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide[periplasmic space] → a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing)[periplasmic space] + D-alanine[periplasmic space] ,
S-adenosyl-L-methionine + precorrin-1 → S-adenosyl-L-homocysteine + precorrin-2 ,
L-glutamate + ATP + NADPH + H+ → ADP + L-glutamate-5-semialdehyde + NADP+ + phosphate ,
a 2-thiouridine34 in tRNA + GTP + glycine + a 5,10-methylene-tetrahydrofolate + H2O = a 5-carboxymethylaminomethyl-2-thiouridine in tRNA + GDP + a 7,8-dihydrofolate + phosphate ,
a 5-methylaminomethyl-2-thiouridine in tRNA + selenophosphate → a 5-methylaminomethyl-2-selenouridine in tRNA + thiophosphate ,
7,8-dihydroneopterin ↔ 7,8-dihydromonapterin ,
an L-1-phosphatidylethanolamine[periplasmic space] + lipid A-core[periplasmic space] → a 1,2-diacyl-sn-glycerol[periplasmic space] + lipid A-core-phosphoethanolamine (hep II)[periplasmic space] ,
aldehydo-D-mannose → D-mannopyranose ,
O-phospho-L-tyrosine[periplasmic space] + H2O[periplasmic space] → L-tyrosine[periplasmic space] + phosphate[periplasmic space] ,
aldehydo-D-ribose ↔ D-ribofuranose ,
2'-deoxyadenosine + 2 hydroxyl radical → 2-hydroxydeoxyadenosine + H2O ,
keto-L-rhamnulose → L-rhamnulofuranose ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine) pentapeptide + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) → a mature peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H+ ,
(S)-2-acetolactate + an oxidized unknown electron acceptor + H+ → diacetyl + CO2 + an reduced unknown electron acceptor ,
heme b + hydrogen peroxide = heme d ,
3-keto-L-gulonate + ATP → 3-keto-L-gulonate 6-phosphate + ADP + H+ ,
4-amino-2-methyl-5-diphosphomethylpyrimidine + H2O → 4-amino-2-methyl-5-phosphomethylpyrimidine + phosphate + H+ ,
S-adenosyl-L-methionine + uroporphyrinogen-III → S-adenosyl-L-homocysteine + precorrin-1 + H+ ,
2-oxopent-4-enoate ↔ (3Z)-2-oxopent-3-enoate ,
XMP + ammonium + ATP → GMP + AMP + diphosphate + 2 H+ ,
(S)-3-hydroxybutanoyl-CoA + H2O → (S)-3-hydroxybutanoate + coenzyme A + H+ ,
2-hydroxyethyldisulfide + 2 glutathione = 2 2-mercaptoethanol + glutathione disulfide ,
D-serine → 2-aminoprop-2-enoate + H2O + H+ ,
3-oxo-5,6-didehydrosuberyl-CoA semialdehyde → 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA + H2O ,
fructoselysine 6-phosphate + H2O ↔ β-D-glucose 6-phosphate + L-lysine ,
4-phospho-hydroxy-L-threonine + NAD+(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + NADH + H+ ,
glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH ,
selenite + 4 glutathione + 2 H+ → selenodiglutathione + glutathione disulfide + 3 H2O ,
(1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate → (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate ,
ATP + an aliphatic sulfonate[periplasmic space] + H2O → an aliphatic sulfonate[cytosol] + ADP + phosphate + H+ ,
aldehydo-D-glucose → D-glucopyranose ,
D-arabinopyranose → aldehydo-D-arabinose ,
(Z)-3-ureidoacrylate peracid + NADH → 3-ureidoacrylate + NAD+ + H2O ,
a phosphorylated phosphoglucosamine mutase + D-glucosamine 6-phosphate = glucosamine 1,6-diphosphate + a phosphoglucosamine mutase ,
(2,3-dihydroxybenzoylserine)3 + 2 H2O = 3 N-(2,3-dihydroxybenzoyl)-L-serine + 2 H+ ,
formaldehyde + a tetrahydrofolate → a 5,10-methylene-tetrahydrofolate + H2O ,
GS-methylhydroquinone + glutathione = methyl-p-hydroquinone + glutathione disulfide ,
(2S)-2-amino-3-oxo-4-phosphonooxybutanoate + H+ → 3-amino-1-hydroxyacetone 1-phosphate + CO2 ,
a uridine34 in tRNA + GTP + a 5,10-methylene-tetrahydrofolate + glycine + H2O = a 5-carboxymethylaminomethyluridine in tRNA + GDP + a 7,8-dihydrofolate + phosphate ,
(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ,
2-oxo-4-methylthiobutanoate + hydroxyl radical → ethylene + methanethiol + 2 CO2 ,
2-carboxy-L-xylonolactone + H2O → 2-carboxy-L-threo-pentonate + H+ ,
lipid A-core[periplasmic space] + colanic acid[periplasmic space] → MLPS[periplasmic space] + H2O[periplasmic space] ,
L-arabinofuranose ↔ L-arabinopyranose ,
dihydrocurcumin + NADPH + H+ → tetrahydrocurcumin + NADP+ ,
4-deoxy-L-threo-hex-4-enopyranuronate ↔ 5-dehydro-4-deoxy-D-glucuronate ,
D-ribulose 1-phosphate ↔ glycolaldehyde + glycerone phosphate ,
2 L-ascorbate + hydrogen peroxide + 2 H+ → 2 monodehydroascorbate radical + 2 H2O ,
aminomethylphosphonate + acetyl-CoA = 2-N-acetamidomethylphosphonate + coenzyme A ,
oxalosuccinate + H+ = 2-oxoglutarate + CO2 ,
a [protein] acetyl-L-lysine + NAD+ + H2O → a [protein]-L-lysine + 3''-O-acetyl-ADP-ribose + nicotinamide ,
a 2-acyl-1-lyso-phosphatidylethanolamine + glycerophosphoglycerol = sn-glycero-3-phosphoethanolamine + a lyso-phospholipid ,
glutathione[cytosol] + ATP + H2O → glutathione[periplasmic space] + ADP + phosphate + H+ ,
(S)-1-pyrroline-5-carboxylate + H+ + H2O ↔ L-glutamate-5-semialdehyde ,
α-D-glucopyranose 1-phosphate ↔ β-D-glucose 1-phosphate ,
2,3-dihydroxybenzoate[periplasmic space] + oxygen[periplasmic space] → 2-carboxymuconate[periplasmic space] + 2 H+[periplasmic space] ,
tetrahydrothiophene 1-oxide[periplasmic space] + an reduced unknown electron acceptor[periplasmic space] = tetrahydrothiophene[periplasmic space] + an oxidized unknown electron acceptor[periplasmic space] + H2O[periplasmic space] ,
(2S)-2-isopropylmalate ↔ 2-isopropylmaleate + H2O ,
L-rhamnopyranose ↔ L-rhamnofuranose ,
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2 ,
(Z)-2-methylureidoacrylate peracid + H2O → (Z)-2-methyl-peroxyaminoacrylate + carbamate + H+ ,
an L-1-phosphatidyl-glycerol + ATP → an L-1-phosphatidylglycerol-phosphate + ADP + H+ ,
histidinal + NAD+ + H2O → L-histidine + NADH + 2 H+ ,
2-trans,5-cis-tetradecadienoyl-CoA + H2O → 3-hydroxy-5-cis-tetradecenoyl-CoA ,
N6-dimethylallyladenosine37 in tRNA + a sulfurated [sulfur carrier] + S-adenosyl-L-methionine + an reduced unknown electron acceptor = 2-thio-N6-dimethylallyladenosine37 in tRNA + an unsulfurated [sulfur carrier] + 5'-deoxyadenosine + L-methionine + an oxidized unknown electron acceptor + H+ ,
7,8-dihydromonapterin triphosphate + 3 H2O → 7,8-dihydromonapterin + 3 phosphate + 2 H+ ,
D-fructose 6-phosphate ↔ β-D-fructofuranose 6-phosphate ,
L-allo-threonine + NADP+ = 2-amino-3-oxobutanoate + NADPH + H+ ,
a 5-carboxymethylaminomethyl-2-thiouridine in tRNA → a 5-aminomethyl-2-thiouridine in tRNA + glyoxylate ,
5-nitro benzisoxazole = 4-nitro 2-cyanophenol ,
L-serine + NADP+ = 3-oxo-L-alanine + NADPH + H+ ,
5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O → 5-amino-6-(D-ribitylamino)uracil + phosphate ,
2 S-sulfanylglutathione + an reduced unknown electron acceptor ↔ bisorganyltrisulfane + hydrogen sulfide + an oxidized unknown electron acceptor ,
Cr6+ + 2 NAD(P)H + oxygen → Cr3+ + superoxide + 2 NAD(P)+ + 2 H+ ,
peptidoglycan tetrapeptide, glycan chain 2 + peptidoglycan tetrapeptide, glycan chain 1 → peptidoglycan DAP-DAP crosslink + D-alanine + H+ ,
D-altropyranose ↔ aldehydo-D-altrose ,
adenine + 2 hydroxyl radical → isoguanine + H2O ,
hydrogen sulfide + glutathione disulfide → S-sulfanylglutathione + glutathione ,
a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine) tetrapeptide[periplasmic space] + glycine[periplasmic space] → a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide[periplasmic space] + D-alanine[periplasmic space] ,
2-oxepin-2(3H)-ylideneacetyl-CoA + NADP+ + 2 H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H+ ,
NADH + a menaquinone[inner membrane] + H+ → NAD+ + a menaquinol[inner membrane] ,
4 H+[in] → 4 H+[out] ,
n H+[in] → n H+[out] ,
dimethyl sulfoxide[periplasmic space] → dimethyl sulfoxide[cytosol] ,
ferric coprogen[extracellular space] → ferric coprogen[cytosol] ,
D-cystine[periplasmic space] → D-cystine[cytosol] ,
cholate[periplasmic space] → cholate[cytosol] ,
salicyl alcohol[cytosol] → salicyl alcohol[periplasmic space] ,
benzene-1,4-diol[cytosol] → benzene-1,4-diol[periplasmic space] ,
L-glyceraldehyde 3-phosphate[periplasmic space] → L-glyceraldehyde 3-phosphate[cytosol] ,
poly-β-1,6-N-acetyl-D-glucosamine[cytosol] → poly-β-1,6-N-acetyl-D-glucosamine[periplasmic space] ,
arsenite[periplasmic space] → arsenite[cytosol] ,
carbon monoxide[periplasmic space] ↔ carbon monoxide[cytosol] ,
allantoin[periplasmic space] → allantoin[cytosol] ,
dihydroxyacetone[periplasmic space] → dihydroxyacetone[cytosol] ,
GMP[cytosol] → GMP[periplasmic space] ,
IMP[cytosol] → IMP[periplasmic space] ,
β-D-glucopyranose[periplasmic space] → β-D-glucopyranose[cytosol] ,
maltose[periplasmic space] → maltose[cytosol] ,
α-lactose[cytosol] + H+[periplasmic space] → α-lactose[periplasmic space] + H+[cytosol] ,
D-glucarate[periplasmic space] → D-glucarate[cytosol] ,
ATP + L-isoleucine[periplasmic space] + H2O → ADP + L-isoleucine[cytosol] + phosphate + H+ ,
β-L-lyxopyranose[periplasmic space] + H+[periplasmic space] → β-L-lyxopyranose[cytosol] + H+[cytosol] ,
ATP + L-leucine[periplasmic space] + H2O → ADP + L-leucine[cytosol] + phosphate + H+ ,
4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[cytosol] → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate[periplasmic space] ,
N-acetyl-β-D-mannosamine[periplasmic space] + HPr-Phis15N-acetyl-D-mannosamine 6-phosphate[cytosol] + HPr ,
3-hydroxypropanoate[cytosol] → 3-hydroxypropanoate[extracellular space] ,
pyruvate[periplasmic space] → pyruvate[cytosol] ,
thymine[cytosol] → thymine[periplasmic space] ,
methyl-β-D-galactoside[periplasmic space] + ATP + H2O → methyl-β-D-galactoside[cytosol] + ADP + phosphate + H+ ,
xanthine[cytosol] → xanthine[periplasmic space] ,
adenine[periplasmic space] → adenine[cytosol] ,
Cu2+[periplasmic space] → Cu2+[cytosol] ,
ferric (2,3-dihydroxybenzoylserine)3[extracellular space] → ferric (2,3-dihydroxybenzoylserine)3[periplasmic space] ,
succinate[cytosol] + fumarate[periplasmic space] → fumarate[cytosol] + succinate[periplasmic space] ,
phosphate[periplasmic space] + H+[periplasmic space] → phosphate[cytosol] + H+[cytosol] ,
Na+[cytosol] + 2 H+[periplasmic space] → Na+[periplasmic space] + 2 H+[cytosol] ,
4-aminobutanoate[cytosol] + L-glutamate[periplasmic space] → L-glutamate[cytosol] + 4-aminobutanoate[periplasmic space] ,
D-serine[periplasmic space] + H+[periplasmic space] → D-serine[cytosol] + H+[cytosol] ,
K+[cytosol] + H+[periplasmic space] → K+[periplasmic space] + H+[cytosol] ,
β-alanine[periplasmic space] + H+[periplasmic space] → β-alanine[cytosol] + H+[cytosol] ,
a drug[cytosol] + H+[periplasmic space] → a drug[extracellular space] + H+[cytosol] ,
Cu+[cytosol] + ATP + H2O → Cu+[periplasmic space] + ADP + phosphate + H+ ,
Cd2+[cytosol] + H+[periplasmic space] → Cd2+[periplasmic space] + H+[cytosol] ,
N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol[cytosol]N-acetyl-α-D-fucosyl-(1→4)-N-acetyl-β-D-mannosaminouronyl-(1→4)-N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol[periplasmic space] ,
N-(2,3-dihydroxybenzoyl)-L-serine[cytosol]N-(2,3-dihydroxybenzoyl)-L-serine[extracellular space] ,
a nucleoside[extracellular space] → a nucleoside[periplasmic space] ,
hypotaurine[periplasmic space] → hypotaurine[cytosol] ,
ethanol[periplasmic space] ↔ ethanol[cytosol] ,
cyclic-AMP[cytosol] ↔ cyclic-AMP[periplasmic space] ,
sulfoquinovose[periplasmic space] → sulfoquinovose[cytosol] ,
a long-chain fatty acid[extracellular space] → a long-chain fatty acid[periplasmic space] ,
Fe2+[periplasmic space] + H+[periplasmic space] → Fe2+[cytosol] + H+[cytosol] ,
a C4-dicarboxylate[periplasmic space] + 3 H+[periplasmic space] → a C4-dicarboxylate[cytosol] + 3 H+[cytosol] ,
Na+[periplasmic space] + L-proline[periplasmic space] → Na+[cytosol] + L-proline[cytosol] ,
uracil[periplasmic space] + H+[periplasmic space] → uracil[cytosol] + H+[cytosol] ,
β-D-galactose[periplasmic space] + H+[periplasmic space] → β-D-galactose[cytosol] + H+[cytosol] ,
glycolate[periplasmic space] → glycolate[cytosol] ,
cystine[cytosol] → cystine[periplasmic space] ,
4-aminobutanoate[periplasmic space] + H+[periplasmic space] → 4-aminobutanoate[cytosol] + H+[cytosol] ,
Li+[periplasmic space] + melibiose[periplasmic space] → Li+[cytosol] + melibiose[cytosol] ,
cadaverine[periplasmic space] + H+[periplasmic space] → cadaverine[cytosol] + H+[cytosol] ,
an aromatic amino acid[cytosol] → an aromatic amino acid[periplasmic space] ,
3-phenylpropanoate[periplasmic space] → 3-phenylpropanoate[cytosol] ,
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[cytosol] → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[periplasmic space] ,
acetylmaltose[cytosol] → acetylmaltose[extracellular space] ,
enterobactin[cytosol] → enterobactin[periplasmic space] ,
L-cystathionine[periplasmic space] → L-cystathionine[cytosol] ,
urate[periplasmic space] + H+[periplasmic space] → urate[cytosol] + H+[cytosol] ,
arsenate[periplasmic space] + H+[periplasmic space] → arsenate[cytosol] + H+[cytosol] ,
acetate[cytosol] ↔ acetate[periplasmic space] ,
sulfate[periplasmic space] + x H+[periplasmic space] → sulfate[cytosol] + x H+[cytosol] ,
cob(I)alamin[extracellular space] → cob(I)alamin[periplasmic space] ,
hydrophilic solute or ion < 600 Da[extracellular space] → hydrophilic solute or ion < 600 Da[periplasmic space] ,
cytidine[periplasmic space] + H+[periplasmic space] → cytidine[cytosol] + H+[cytosol] ,
fumarate[periplasmic space] + 2 H+[periplasmic space] → fumarate[cytosol] + 2 H+[cytosol] ,
cyanate[periplasmic space] → cyanate[cytosol] ,
β-D-fructofuranose[periplasmic space] + HPr-Phis15 → β-D-fructofuranose 6-phosphate[cytosol] + HPr ,
lipid A-core[cytosol] + ATP + H2O → lipid A-core[periplasmic space] + ADP + phosphate + H+ ,
2-nitroimidazole[cytosol] → 2-nitroimidazole[periplasmic space] ,
D-alanine[periplasmic space] + H+[periplasmic space] → D-alanine[cytosol] + H+[cytosol] ,
L-threonine[cytosol] + H+[periplasmic space] → L-threonine[periplasmic space] + H+[cytosol] ,
ATP + L-proline[periplasmic space] + H2O → ADP + L-proline[cytosol] + phosphate + H+ ,
ATP + L-alanyl-γ-D-glutamyl-meso-diaminopimelate[periplasmic space] + H2O → L-alanyl-γ-D-glutamyl-meso-diaminopimelate[cytosol] + ADP + phosphate + H+ ,
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[cytosol]ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine[periplasmic space] ,
3-hydroxy-trans-cinnamate[periplasmic space] + H+[periplasmic space] → 3-hydroxy-trans-cinnamate[cytosol] + H+[cytosol] ,
ethanolamine[periplasmic space] → ethanolamine[cytosol] ,
D-tartrate[periplasmic space] + succinate[cytosol] → succinate[periplasmic space] + D-tartrate[cytosol] ,
(R)-lactate[periplasmic space] + H+[periplasmic space] → (R)-lactate[cytosol] + H+[cytosol] ,
L-glyceraldehyde 3-phosphate[periplasmic space] + phosphate[cytosol] → L-glyceraldehyde 3-phosphate[cytosol] + phosphate[periplasmic space] ,
fumarate[periplasmic space] → fumarate[cytosol] ,
pyruvate[cytosol] → pyruvate[periplasmic space] ,
N-acetylneuraminate[extracellular space]N-acetylneuraminate[periplasmic space] ,
deoxycholate[cytosol] + H+[periplasmic space] → deoxycholate[periplasmic space] + H+[cytosol] ,
enterobactin[cytosol] → enterobactin[extracellular space] ,
ferric enterobactin complex[extracellular space] → ferric enterobactin complex[cytosol] ,
mono-, di-, or trisaccharide < 600 Da[extracellular space] → mono-, di-, or trisaccharide < 600 Da[periplasmic space] ,
3 a DHB-seryl-[EntF peptidyl-carrier protein] → enterobactin + 3 a holo-[EntF peptidyl-carrier protein] ,
2'-deoxyinosine[periplasmic space] + H+[periplasmic space] → 2'-deoxyinosine[cytosol] + H+[cytosol] ,
L-aspartate[periplasmic space] + 2 H+[periplasmic space] → L-aspartate[cytosol] + 2 H+[cytosol] ,
Ni2+[periplasmic space] → Ni2+[cytosol] ,
L-glutamate[periplasmic space] + 2 H+[periplasmic space] → L-glutamate[cytosol] + 2 H+[cytosol] ,
α-lactose[periplasmic space] + H+[periplasmic space] → α-lactose[cytosol] + H+[cytosol] ,
K+[periplasmic space] + H+[periplasmic space] → K+[cytosol] + H+[cytosol] ,
putrescine[periplasmic space] + H+[periplasmic space] → putrescine[cytosol] + H+[cytosol] ,
Zn2+[cytosol] + H+[periplasmic space] → Zn2+[periplasmic space] + H+[cytosol] ,
aldehydo-L-galactonate[periplasmic space] + H+[periplasmic space]aldehydo-L-galactonate[cytosol] + H+[cytosol] ,
octanoate[periplasmic space] → octanoate[cytosol] ,
psicoselysine[periplasmic space] → psicoselysine[cytosol] ,
S-methyl-5-thio-D-ribose[cytosol]S-methyl-5-thio-D-ribose[periplasmic space] ,
L-selenocysteine[periplasmic space] → L-selenocysteine[cytosol] ,
α-D-mannose 6-phosphate[periplasmic space] + phosphate[cytosol] → α-D-mannose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
methyl-α-D-galactopyranoside[periplasmic space] + H+[periplasmic space] → methyl-α-D-galactopyranoside[cytosol] + H+[cytosol] ,
glycine[periplasmic space] ↔ glycine[cytosol] ,
a glycerophosphodiester[periplasmic space] + ATP + H2O → a glycerophosphodiester[cytosol] + ADP + phosphate + H+ ,
glutathione[periplasmic space] + ATP + H2O → glutathione[cytosol] + ADP + phosphate + H+ ,
chenodeoxycholate[cytosol] + H+[periplasmic space] → chenodeoxycholate[periplasmic space] + H+[cytosol] ,
ferric dicitrate[extracellular space] → ferric dicitrate[periplasmic space] ,
ferrichrome[extracellular space] → ferrichrome[cytosol] ,
γ-butyrobetaine[cytosol] + L-carnitine[periplasmic space] → γ-butyrobetaine[periplasmic space] + L-carnitine[cytosol] ,
thymidine[periplasmic space] + H+[periplasmic space] → thymidine[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + L-isoleucine[periplasmic space] → Na+[cytosol] + L-isoleucine[cytosol] ,
Ca2+[cytosol] → Ca2+[periplasmic space] ,
homoserine lactone[cytosol] + H+[periplasmic space] → homoserine lactone[periplasmic space] + H+[cytosol] ,
β-D-glucose 6-phosphate[periplasmic space] + phosphate[cytosol] → β-D-glucose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
L-tryptophan[periplasmic space] + H+[periplasmic space] → L-tryptophan[cytosol] + H+[cytosol] ,
D-fructuronate[periplasmic space] + H+[periplasmic space] → D-fructuronate[cytosol] + H+[cytosol] ,
galactarate[periplasmic space] → galactarate[cytosol] ,
Na+[periplasmic space] + 2,3-dioxo-L-gulonate[periplasmic space] → Na+[cytosol] + 2,3-dioxo-L-gulonate[cytosol] ,
partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine[periplasmic space] → partially N-deacetylated poly-β-1,6-N-acetyl-D-glucosamine[extracellular space] ,
N,N'-diacetylchitobiose[extracellular space]N,N'-diacetylchitobiose[periplasmic space] ,
4-methyl-5-(β-hydroxyethyl)thiazole[periplasmic space] → 4-methyl-5-(β-hydroxyethyl)thiazole[cytosol] ,
Mn2+[cytosol] → Mn2+[periplasmic space] ,
propanoate[periplasmic space] → propanoate[cytosol] ,
D-glycerate[periplasmic space] → D-glycerate[cytosol] ,
uracil[cytosol] → uracil[periplasmic space] ,
tellurite[periplasmic space] → tellurite[cytosol] ,
a drug[cytosol] → a drug[periplasmic space] ,
ferric coprogen[extracellular space] → ferric coprogen[periplasmic space] ,
glycolate[periplasmic space] + H+[periplasmic space] → glycolate[cytosol] + H+[cytosol] ,
2-dehydro-3-deoxy-D-gluconate[periplasmic space] + H+[periplasmic space] → 2-dehydro-3-deoxy-D-gluconate[cytosol] + H+[cytosol] ,
L-tartrate[periplasmic space] + succinate[cytosol] → L-tartrate[cytosol] + succinate[periplasmic space] ,
nitrite[cytosol] + H+[periplasmic space] → nitrite[periplasmic space] + H+[cytosol] ,
fosmidomycin[cytosol] + H+[periplasmic space] → fosmidomycin[periplasmic space] + H+[cytosol] ,
Ag+[cytosol] + H+[periplasmic space] → Ag+[extracellular space] + H+[cytosol] ,
ammonium[periplasmic space] ↔ ammonium[cytosol] ,
biotin[periplasmic space] → biotin[cytosol] ,
(R)-lipoate[periplasmic space] → (R)-lipoate[cytosol] ,
1-deoxy-D-xylulose[periplasmic space] → 1-deoxy-D-xylulose[cytosol] ,
N-acetyl-β-neuraminate[extracellular space]N-acetyl-β-neuraminate[periplasmic space] ,
(R)-propane-1,2-diol[cytosol] → (R)-propane-1,2-diol[periplasmic space] ,
djenkolate[periplasmic space] → djenkolate[cytosol] ,
methane[cytosol] → methane[periplasmic space] ,
CO2[periplasmic space] ↔ CO2[cytosol] ,
indole[cytosol] ↔ indole[periplasmic space] ,
hypoxanthine[cytosol] → hypoxanthine[periplasmic space] ,
L-arginine[periplasmic space] ← L-arginine[cytosol] ,
inosine[cytosol] + H+[periplasmic space] → inosine[periplasmic space] + H+[cytosol] ,
succinate[cytosol] + (S)-malate[periplasmic space] → (S)-malate[cytosol] + succinate[periplasmic space] ,
Na+[periplasmic space] + (R)-pantothenate[periplasmic space] → Na+[cytosol] + (R)-pantothenate[cytosol] ,
glycerol[periplasmic space] ↔ glycerol[cytosol] ,
a peptide antibiotic[periplasmic space] → a peptide antibiotic[cytosol] ,
L-phenylalanine[periplasmic space] + H+[periplasmic space] → L-phenylalanine[cytosol] + H+[cytosol] ,
D-cycloserine[periplasmic space] + H+[periplasmic space] → D-cycloserine[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + melibiose[periplasmic space] → Na+[cytosol] + melibiose[cytosol] ,
putrescine[cytosol] + L-ornithine[periplasmic space] → putrescine[periplasmic space] + L-ornithine[cytosol] ,
arsenite[cytosol] + H+[periplasmic space] → arsenite[periplasmic space] + H+[cytosol] ,
acetoacetate[periplasmic space] → acetoacetate[cytosol] ,
Fe2+[cytosol] + H+[periplasmic space] → Fe2+[periplasmic space] + H+[cytosol] ,
p-aminobenzoyl glutamate[periplasmic space] + H+[periplasmic space]p-aminobenzoyl glutamate[cytosol] + H+[cytosol] ,
phosphate[cytosol] → phosphate[periplasmic space] ,
D-serine[periplasmic space] → D-serine[cytosol] ,
L-methionine S-oxide[periplasmic space] + ATP + H2O → L-methionine S-oxide[cytosol] + ADP + phosphate + H+ ,
Co2+[cytosol] → Co2+[periplasmic space] ,
adenosine[periplasmic space] + H+[periplasmic space] → adenosine[cytosol] + H+[cytosol] ,
(S)-malate[periplasmic space] + 2 H+[periplasmic space] → (S)-malate[cytosol] + 2 H+[cytosol] ,
chloride[periplasmic space] ← chloride[cytosol] ,
β-D-fructofuranose[periplasmic space] + PtsI-Phis189 → β-D-fructofuranose 1-phosphate[cytosol] + PtsI ,
2-oxoglutarate[periplasmic space] + H+[periplasmic space] → 2-oxoglutarate[cytosol] + H+[cytosol] ,
FAD[cytosol] → FAD[periplasmic space] ,
3-(3-hydroxyphenyl)propanoate[periplasmic space] + H+[periplasmic space] → 3-(3-hydroxyphenyl)propanoate[cytosol] + H+[cytosol] ,
choline[periplasmic space] + H+[periplasmic space] → choline[cytosol] + H+[cytosol] ,
pyridoxal[periplasmic space] → pyridoxal[cytosol] ,
a tripeptide[periplasmic space] + H+[periplasmic space] → a tripeptide[cytosol] + H+[cytosol] ,
phenylacetaldehyde[periplasmic space] → phenylacetaldehyde[cytosol] ,
cobinamide[extracellular space] → cobinamide[cytosol] ,
d-biotin d-sulfoxide[periplasmic space]d-biotin d-sulfoxide[cytosol] ,
fluoride[cytosol] → fluoride[periplasmic space] ,
choline[cytosol] + 2 H+[periplasmic space] → choline[periplasmic space] + 2 H+[cytosol] ,
succinate[periplasmic space] → succinate[cytosol] ,
thiamin diphosphate + phosphate + n H+[periplasmic space] → thiamin triphosphate + H2O + n H+[cytosol] ,
L-lysine[cytosol] → L-lysine[periplasmic space] ,
cholate[cytosol] + H+[periplasmic space] → cholate[periplasmic space] + H+[cytosol] ,
agmatine[cytosol] + L-arginine[periplasmic space] → agmatine[periplasmic space] + L-arginine[cytosol] ,
2'-deoxycytidine[periplasmic space] + H+[periplasmic space] → 2'-deoxycytidine[cytosol] + H+[cytosol] ,
2 Na+[periplasmic space] + L-glutamate[periplasmic space] → 2 Na+[cytosol] + L-glutamate[cytosol] ,
Co2+[periplasmic space] → Co2+[cytosol] ,
an aminoalkylphosphonate[periplasmic space] + ATP + H2O → an aminoalkylphosphonate[cytosol] + ADP + phosphate + H+ ,
glycine betaine[periplasmic space] + H+[periplasmic space] → glycine betaine[cytosol] + H+[cytosol] ,
cadaverine[cytosol] + L-lysine[periplasmic space] → cadaverine[periplasmic space] + L-lysine[cytosol] ,
a polypeptide[cytosol] → a polypeptide[periplasmic space] ,
pyruvate[in] + 2 H+[in] + 2 e-[membrane] → (S)-lactate[in] ,
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[periplasmic space] + H+[periplasmic space] → GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[cytosol] + H+[cytosol] ,
L-leucine[cytosol] + H+[periplasmic space] → L-leucine[periplasmic space] + H+[cytosol] ,
ATP + a dipeptide[periplasmic space] + H2O → ADP + a dipeptide[cytosol] + phosphate + H+ ,
D-fructosyl-L-lysine[periplasmic space] → D-fructosyl-L-lysine[cytosol] ,
urea[cytosol] ↔ urea[periplasmic space] ,
selenite[periplasmic space] + ATP + H2O → selenite[cytosol] + ADP + phosphate + H+ ,
β-D-fructofuranose 6-phosphate[periplasmic space] + phosphate[cytosol] → β-D-fructofuranose 6-phosphate[cytosol] + phosphate[periplasmic space] ,
methyl β-D-glucoside[periplasmic space] + HPr-Phis15 → methyl β-D-glucoside 6-phosphate[cytosol] + HPr ,
DL-glyceraldehyde[periplasmic space] ↔ DL-glyceraldehyde[cytosol] ,
L-methionine[cytosol] + H+[periplasmic space] → L-methionine[periplasmic space] + H+[cytosol] ,
hydrogen peroxide[periplasmic space] → hydrogen peroxide[extracellular space] ,
chenodeoxycholate[periplasmic space] → chenodeoxycholate[cytosol] ,
ferric enterobactin complex[extracellular space] → ferric enterobactin complex[periplasmic space] ,
L-cysteine[cytosol] ↔ L-cysteine[periplasmic space] ,
L-arabinose[periplasmic space] + H+[periplasmic space] → L-arabinose[cytosol] + H+[cytosol] ,
inosine[periplasmic space] + H+[periplasmic space] → inosine[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + L-alanine[periplasmic space] → Na+[cytosol] + L-alanine[cytosol] ,
K+[periplasmic space] → K+[cytosol] ,
HPr-Phis15 + N-acetyl-β-D-glucosamine[periplasmic space]N-acetyl-D-glucosamine 6-phosphate[cytosol] + HPr ,
L-homoserine[cytosol] + H+[periplasmic space] → L-homoserine[periplasmic space] + H+[cytosol] ,
xanthosine[periplasmic space] + H+[periplasmic space] → xanthosine[cytosol] + H+[cytosol] ,
L-threonine[periplasmic space] + H+[periplasmic space] → L-threonine[cytosol] + H+[cytosol] ,
ATP + D-methionine[periplasmic space] + H2O → ADP + D-methionine[cytosol] + phosphate + H+ ,
4-hydroxybenzoate[cytosol] + H+[periplasmic space] → 4-hydroxybenzoate[periplasmic space] + H+[cytosol] ,
4-hydroxybenzyl alcohol[cytosol] → 4-hydroxybenzyl alcohol[periplasmic space] ,
(S)-(+)-allantoin[periplasmic space] → (S)-(+)-allantoin[cytosol] ,
nitrate[out] + 2 H+[out] + 2 e-[membrane] → nitrite[out] + H2O[out] ,
5,6-dimethylbenzimidazole[periplasmic space] → 5,6-dimethylbenzimidazole[cytosol] ,
S-methyl-L-methionine[periplasmic space] → S-methyl-L-methionine[cytosol] ,
D-galactono-1,4-lactone[periplasmic space] → D-galactono-1,4-lactone[cytosol] ,
ethidium[cytosol] → ethidium[periplasmic space] ,
FMN[cytosol] → FMN[periplasmic space] ,
ferrichrome[extracellular space] → ferrichrome[periplasmic space] ,
glyoxylate[periplasmic space] → glyoxylate[cytosol] ,
(S)-lactate[periplasmic space] + H+[periplasmic space] → (S)-lactate[cytosol] + H+[cytosol] ,
L-rhamnose[periplasmic space] + H+[periplasmic space] → L-rhamnose[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + L-leucine[periplasmic space] → Na+[cytosol] + L-leucine[cytosol] ,
Na+[periplasmic space] + L-serine[periplasmic space] → Na+[cytosol] + L-serine[cytosol] ,
an O-antigen[cytosol] → an O-antigen[periplasmic space] ,
an mRNA + H2O → an RNase product with a 3' phosphate + an RNase product with a 5' OH ,
L-arabinose[cytosol] + H+[periplasmic space] → L-arabinose[periplasmic space] + H+[cytosol] ,
Fe2+[periplasmic space] → Fe2+[cytosol] ,
non-specific ion/solute[cytosol] → non-specific ion/solute[periplasmic space] ,
pyridoxine[periplasmic space] → pyridoxine[cytosol] ,
nitrate[periplasmic space] + nitrite[cytosol] → nitrate[cytosol] + nitrite[periplasmic space] ,
ATP + L-valine[periplasmic space] + H2O → ADP + L-valine[cytosol] + phosphate + H+ ,
adenine[periplasmic space] + H+[periplasmic space] → adenine[cytosol] + H+[cytosol] ,
acetate[in] + CO2[in] + 2 H+[in] + 2 e-[membrane] → pyruvate[in] + H2O[in] ,
N-acetyl-β-neuraminate[periplasmic space] + H+[periplasmic space]N-acetyl-β-neuraminate[cytosol] + H+[cytosol] ,
trans-cinnamate[periplasmic space]trans-cinnamate[cytosol] ,
glycine betaine[extracellular space] ↔ glycine betaine[periplasmic space] ,
L-cystine[periplasmic space] → L-cystine[cytosol] ,
(3E,5Z)-tetradecadienoate[cytosol] → (3E,5Z)-tetradecadienoate[periplasmic space] ,
ammonia[periplasmic space] ↔ ammonia[cytosol] ,
hypoxanthine[cytosol] ← hypoxanthine[periplasmic space] ,
D-glucopyranose[periplasmic space] + H+[periplasmic space] → D-glucopyranose[cytosol] + H+[cytosol] ,
guanine[periplasmic space] → guanine[cytosol] ,
maltose[extracellular space] → maltose[periplasmic space] ,
succinate[cytosol] + L-aspartate[periplasmic space] → L-aspartate[cytosol] + succinate[periplasmic space] ,
cytosine[periplasmic space] + H+[periplasmic space] → cytosine[cytosol] + H+[cytosol] ,
2 Na+[cytosol] + 3 H+[periplasmic space] → 2 Na+[periplasmic space] + 3 H+[cytosol] ,
HPr-Phis15 + β-D-cellobiose[periplasmic space] → β-D-cellobiose 6'-phosphate[cytosol] + HPr ,
L-fucose[periplasmic space] + H+[periplasmic space] → L-fucose[cytosol] + H+[cytosol] ,
L-asparagine[periplasmic space] + H+[periplasmic space] → L-asparagine[cytosol] + H+[cytosol] ,
a drug[cytosol] + H+[periplasmic space] → a drug[periplasmic space] + H+[cytosol] ,
L-alanine[periplasmic space] + H+[periplasmic space] → L-alanine[cytosol] + H+[cytosol] ,
melibiose[periplasmic space] + H+[periplasmic space] → melibiose[cytosol] + H+[cytosol] ,
D-gluconate[periplasmic space] + H+[periplasmic space] → D-gluconate[cytosol] + H+[cytosol] ,
N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[periplasmic space] + H+[periplasmic space]N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[cytosol] + H+[cytosol] ,
D-allose[periplasmic space] + ATP + H2O → D-allose[cytosol] + ADP + phosphate + H+ ,
Cu+[cytosol] + H+[periplasmic space] → Cu+[extracellular space] + H+[cytosol] ,
(R)-malate[periplasmic space] + 2 H+[periplasmic space] → (R)-malate[cytosol] + 2 H+[cytosol] ,
L-alanine[cytosol] → L-alanine[periplasmic space] ,
a drug[cytosol] + 2 H+[periplasmic space] → a drug[periplasmic space] + 2 H+[cytosol] ,
N-acetyl-DL-methionine[periplasmic space] + ATP + H2O → N-acetyl-DL-methionine[cytosol] + ADP + phosphate + H+ ,
H2O[periplasmic space] ↔ H2O[cytosol] ,
Ni2+[cytosol] → Ni2+[periplasmic space] ,
non-specific ion/solute[extracellular space] → non-specific ion/solute[periplasmic space] ,
a nucleoside[periplasmic space] + H+[periplasmic space] → a nucleoside[cytosol] + H+[cytosol] ,
succinate[periplasmic space] + 2 H+[periplasmic space] → succinate[cytosol] + 2 H+[cytosol] ,
nitrite[periplasmic space] → nitrite[cytosol] ,
sn-glycerol 3-phosphate[periplasmic space] + phosphate[cytosol]sn-glycerol 3-phosphate[cytosol] + phosphate[periplasmic space] ,
shikimate[periplasmic space] + H+[periplasmic space] → shikimate[cytosol] + H+[cytosol] ,
L-lysine[periplasmic space] + H+[periplasmic space] → L-lysine[cytosol] + H+[cytosol] ,
a D-glucoronoside[periplasmic space] + H+[periplasmic space] → a D-glucoronoside[cytosol] + H+[cytosol] ,
pyridoxamine[periplasmic space] → pyridoxamine[cytosol] ,
ubiquinone-8[membrane] + 2 H+[in] + 2 e-[membrane] → ubiquinol-8[membrane] ,
spermidine[cytosol] + H+[periplasmic space] → spermidine[periplasmic space] + H+[cytosol] ,
Zn2+[periplasmic space] + ATP + H2O → Zn2+[cytosol] + ADP + phosphate + H+ ,
cobinamide[extracellular space] → cobinamide[periplasmic space] ,
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[periplasmic space] + ATP + H2O → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran[cytosol] + ADP + phosphate + H+ ,
oxygen[periplasmic space] ↔ oxygen[cytosol] ,
Ca2+[periplasmic space] → Ca2+[cytosol] ,
lanthionine[periplasmic space] → lanthionine[cytosol] ,
xanthine[periplasmic space] + H+[periplasmic space] → xanthine[cytosol] + H+[cytosol] ,
glycine betaine[cytosol] + 2 H+[periplasmic space] → glycine betaine[periplasmic space] + 2 H+[cytosol] ,
lactate[cytosol] ↔ lactate[periplasmic space] ,
1,6-anhydro-N-acetyl-β-muramate[periplasmic space] → 1,6-anhydro-N-acetyl-β-muramate[cytosol] ,
Mn2+[periplasmic space] → Mn2+[cytosol] ,
cob(I)alamin[extracellular space] → cob(I)alamin[cytosol] ,
2 chloride[periplasmic space] + H+[cytosol] → 2 chloride[cytosol] + H+[periplasmic space] ,
2'-deoxyadenosine[periplasmic space] + H+[periplasmic space] → 2'-deoxyadenosine[cytosol] + H+[cytosol] ,
orotate[periplasmic space] + 2 H+[periplasmic space] → orotate[cytosol] + 2 H+[cytosol] ,
Mg2+[periplasmic space] → Mg2+[cytosol] ,
D-galactonate[periplasmic space] + H+[periplasmic space] → D-galactonate[cytosol] + H+[cytosol] ,
a lipopolysaccharide[cytosol] → a lipopolysaccharide[extracellular space] ,
L-proline[periplasmic space] + H+[periplasmic space] → L-proline[cytosol] + H+[cytosol] ,
glycine[periplasmic space] + H+[periplasmic space] → glycine[cytosol] + H+[cytosol] ,
a macrolide antibiotic[cytosol] + ATP + H2O → a macrolide antibiotic[extracellular space] + ADP + phosphate ,
L-valine[cytosol] → L-valine[periplasmic space] ,
a dipeptide[periplasmic space] + H+[periplasmic space] → a dipeptide[cytosol] + H+[cytosol] ,
methanol[cytosol] → methanol[periplasmic space] ,
selenate[periplasmic space] + ATP + H2O → selenate[cytosol] + ADP + phosphate + H+ ,
4-methylphenol[cytosol] → 4-methylphenol[periplasmic space] ,
a C4-dicarboxylate[periplasmic space] + 2 H+[periplasmic space] → a C4-dicarboxylate[cytosol] + 2 H+[cytosol] ,
L-aspartate[periplasmic space] → L-aspartate[cytosol] ,
acetate[periplasmic space] + H+[periplasmic space] → acetate[cytosol] + H+[cytosol] ,
Cd2+[periplasmic space] → Cd2+[cytosol] ,
deoxycholate[periplasmic space] → deoxycholate[cytosol] ,
O-acetyl-L-serine[cytosol]O-acetyl-L-serine[periplasmic space] ,
guanosine[cytosol] + H+[periplasmic space] → guanosine[periplasmic space] + H+[cytosol] ,
a drug[cytosol] + Na+[periplasmic space] → a drug[periplasmic space] + Na+[cytosol] ,
formate[cytosol] ↔ formate[periplasmic space] ,
2'-deoxyuridine[periplasmic space] + H+[periplasmic space] → 2'-deoxyuridine[cytosol] + H+[cytosol] ,
D-galacturonate[periplasmic space] + H+[periplasmic space] → D-galacturonate[cytosol] + H+[cytosol] ,
indole[periplasmic space] + H+[periplasmic space] → indole[cytosol] + H+[cytosol] ,
ATP + L-methionine[periplasmic space] + H2O → ADP + L-methionine[cytosol] + phosphate + H+ ,
α-D-mannose[periplasmic space] + HPr-Phis15 → α-D-mannose 6-phosphate[cytosol] + HPr ,
Mn2+[periplasmic space] + H+[periplasmic space] → Mn2+[cytosol] + H+[cytosol] ,
D-xylose[periplasmic space] + H+[periplasmic space] → D-xylose[cytosol] + H+[cytosol] ,
L-serine[periplasmic space] + H+[periplasmic space] → L-serine[cytosol] + H+[cytosol] ,
succinate[cytosol] + citrate[periplasmic space] → citrate[cytosol] + succinate[periplasmic space] ,
5-dehydro-D-gluconate[periplasmic space] + H+[periplasmic space] → 5-dehydro-D-gluconate[cytosol] + H+[cytosol] ,
ATP + thiamin[periplasmic space] + H2O → ADP + thiamin[cytosol] + phosphate + H+ ,
a long-chain fatty acid[periplasmic space] → a long-chain fatty acid[cytosol] ,
4-amino-2-methyl-5-pyrimidinemethanol[periplasmic space] → 4-amino-2-methyl-5-pyrimidinemethanol[cytosol] ,
1-(β-D ribofuranosyl)nicotinamide[periplasmic space] → 1-(β-D ribofuranosyl)nicotinamide[cytosol] ,
methyl-β-D-galactoside[periplasmic space] + Na+[periplasmic space] → methyl-β-D-galactoside[cytosol] + Na+[cytosol] ,
pseudouridine[periplasmic space] → pseudouridine[cytosol] ,
2-oxobutanoate[periplasmic space] → 2-oxobutanoate[cytosol] ,
Zn2+[periplasmic space] → Zn2+[cytosol] ,
acetate[periplasmic space] → acetate[cytosol] ,
ferric dicitrate[extracellular space] → ferric dicitrate[cytosol] ,
Na+[cytosol] + H+[periplasmic space] → Na+[periplasmic space] + H+[cytosol] ,
uridine[periplasmic space] + H+[periplasmic space] → uridine[cytosol] + H+[cytosol] ,
Na+[periplasmic space] + L-valine[periplasmic space] → Na+[cytosol] + L-valine[cytosol] ,
H2O[periplasmic space] ↔ H2O[cytosol] ,
N-acetylneuraminate[periplasmic space] + H+[periplasmic space]N-acetylneuraminate[cytosol] + H+[cytosol] ,
D-glucuronate[periplasmic space] + H+[periplasmic space] → D-glucuronate[cytosol] + H+[cytosol] ,
L-tyrosine[periplasmic space] + H+[periplasmic space] → L-tyrosine[cytosol] + H+[cytosol]


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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