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Escherichia coli K-12 substr. MG1655 Reactions Class: Transport Energised by the Membrane Electrochemical Gradient

Summary:
Transport reactions in this class are catalysed by proteins which use the energy of the membrane electrochemical gradient to drive uptake or export of substrates. These membrane proteins can catalyze uniport (a single species is transported), antiport (two species are transported in opposite directions) or symport (two species are transported together in the same direction). Symporters and antiporters are secondary active transporters which use chemiosmotic energy in the form of a proton, sodium or other solute gradient to drive transport of one substrate against it's concentration gradient. Membrane uniporters in this class catalyse the transport of a substrate down its concentration gradient in a membrane potential dependent process.
Proteins catalysing these reactions are members of IUBMB Transport Classification Family 2

Parent Classes:
Transport Reactions

Child classes:
TonB and TolA Dependent Transport (11)

Instances:
3.6.3.-: L-idonate[periplasm] + H+[periplasm] → L-idonate[cytosol] + H+[cytosol],
chenodeoxycholate[cytosol] + H+[periplasm] → chenodeoxycholate[periplasm] + H+[cytosol],
deoxycholate[cytosol] + H+[periplasm] → deoxycholate[periplasm] + H+[cytosol],
cholate[cytosol] + H+[periplasm] → cholate[periplasm] + H+[cytosol],
sulfate[periplasm] + x H+[periplasm] → sulfate[cytosol] + x H+[cytosol],
acetate[periplasm] + H+[periplasm] → acetate[cytosol] + H+[cytosol],
arsenate[periplasm] + H+[periplasm] → arsenate[cytosol] + H+[cytosol],
L-glyceraldehyde 3-phosphate[periplasm] + phosphate[cytosol] → L-glyceraldehyde 3-phosphate[cytosol] + phosphate[periplasm],
choline[cytosol] + 2 H+[periplasm] → choline[periplasm] + 2 H+[cytosol],
glycine betaine[cytosol] + 2 H+[periplasm] → glycine betaine[periplasm] + 2 H+[cytosol],
urate[periplasm] + H+[periplasm] → urate[cytosol] + H+[cytosol],
methyl-β-D-galactoside[periplasm] + Na+[periplasm] → methyl-β-D-galactoside[cytosol] + Na+[cytosol],
methyl-α-D-galactopyranoside[periplasm] + H+[periplasm] → methyl-α-D-galactopyranoside[cytosol] + H+[cytosol],
a C4-dicarboxylate[periplasm] + 2 H+[periplasm] → a C4-dicarboxylate[cytosol] + 2 H+[cytosol],
(R)-lactate[periplasm] + H+[periplasm] → (R)-lactate[cytosol] + H+[cytosol],
α-D-mannose 6-phosphate[periplasm] + phosphate[cytosol] → α-D-mannose 6-phosphate[cytosol] + phosphate[periplasm],
β-D-fructofuranose 6-phosphate[periplasm] + phosphate[cytosol] → β-D-fructofuranose 6-phosphate[cytosol] + phosphate[periplasm],
D-tartrate[periplasm] + succinate[cytosol] → succinate[periplasm] + D-tartrate[cytosol],
enterobactin[cytosol] → enterobactin[periplasm],
a drug[cytosol] + 2 H+[periplasm] → a drug[periplasm] + 2 H+[cytosol],
3-hydroxy-trans-cinnamate[periplasm] + H+[periplasm] → 3-hydroxy-trans-cinnamate[cytosol] + H+[cytosol],
p-aminobenzoyl glutamate[periplasm] + H+[periplasm]p-aminobenzoyl glutamate[cytosol] + H+[cytosol],
(R)-malate[periplasm] + 2 H+[periplasm] → (R)-malate[cytosol] + 2 H+[cytosol],
adenine[periplasm] + H+[periplasm] → adenine[cytosol] + H+[cytosol],
a dipeptide[periplasm] + H+[periplasm] → a dipeptide[cytosol] + H+[cytosol],
Cu+[cytosol] + H+[periplasm] → Cu+[extracellular space] + H+[cytosol],
L-leucine[cytosol] + H+[periplasm] → L-leucine[periplasm] + H+[cytosol],
a tripeptide[periplasm] + H+[periplasm] → a tripeptide[cytosol] + H+[cytosol],
spermidine[cytosol] + H+[periplasm] → spermidine[periplasm] + H+[cytosol],
an aromatic amino acid[cytosol] → an aromatic amino acid[periplasm],
arsenite[cytosol] + H+[periplasm] → arsenite[periplasm] + H+[cytosol],
N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[periplasm] + H+[periplasm]N-acetyl-β-D-glucosamine(anhydrous)-N-acetylmuramate[cytosol] + H+[cytosol],
Cd2+[cytosol] + H+[periplasm] → Cd2+[periplasm] + H+[cytosol],
nitrate[periplasm] + nitrite[cytosol] → nitrate[cytosol] + nitrite[periplasm],
β-L-lyxopyranose[periplasm] + H+[periplasm] → β-L-lyxopyranose[cytosol] + H+[cytosol],
Na+[periplasm] + 2,3-dioxo-L-gulonate[periplasm] → Na+[cytosol] + 2,3-dioxo-L-gulonate[cytosol],
4-hydroxybenzoate[cytosol] + H+[periplasm] → 4-hydroxybenzoate[periplasm] + H+[cytosol],
5-dehydro-D-gluconate[periplasm] + H+[periplasm] → 5-dehydro-D-gluconate[cytosol] + H+[cytosol],
aldehydo-L-galactonate[periplasm] + H+[periplasm]aldehydo-L-galactonate[cytosol] + H+[cytosol],
GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[periplasm] + H+[periplasm] → GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala[cytosol] + H+[cytosol],
cadaverine[periplasm] + H+[periplasm] → cadaverine[cytosol] + H+[cytosol],
putrescine[cytosol] + L-ornithine[periplasm] → putrescine[periplasm] + L-ornithine[cytosol],
D-gluconate[periplasm] + H+[periplasm] → D-gluconate[cytosol] + H+[cytosol],
succinate[cytosol] + citrate[periplasm] → citrate[cytosol] + succinate[periplasm],
Zn2+[cytosol] + H+[periplasm] → Zn2+[periplasm] + H+[cytosol],
a polypeptide[cytosol] → a polypeptide[periplasm],
L-threonine[cytosol] + H+[periplasm] → L-threonine[periplasm] + H+[cytosol],
choline[periplasm] + H+[periplasm] → choline[cytosol] + H+[cytosol],
a D-glucoronoside[periplasm] + H+[periplasm] → a D-glucoronoside[cytosol] + H+[cytosol],
Li+[periplasm] + melibiose[periplasm] → Li+[cytosol] + melibiose[cytosol],
Na+[periplasm] + melibiose[periplasm] → Na+[cytosol] + melibiose[cytosol],
melibiose[periplasm] + H+[periplasm] → melibiose[cytosol] + H+[cytosol],
a drug[cytosol] + H+[periplasm] → a drug[extracellular space] + H+[cytosol],
Ag+[cytosol] + H+[periplasm] → Ag+[extracellular space] + H+[cytosol],
α-lactose[cytosol] + H+[periplasm] → α-lactose[periplasm] + H+[cytosol],
D-fructuronate[periplasm] + H+[periplasm] → D-fructuronate[cytosol] + H+[cytosol],
L-tyrosine[periplasm] + H+[periplasm] → L-tyrosine[cytosol] + H+[cytosol],
L-tryptophan[periplasm] + H+[periplasm] → L-tryptophan[cytosol] + H+[cytosol],
L-threonine[periplasm] + H+[periplasm] → L-threonine[cytosol] + H+[cytosol],
L-serine[periplasm] + H+[periplasm] → L-serine[cytosol] + H+[cytosol],
putrescine[periplasm] + H+[periplasm] → putrescine[cytosol] + H+[cytosol],
cadaverine[cytosol] + L-lysine[periplasm] → cadaverine[periplasm] + L-lysine[cytosol],
glycine[periplasm] + H+[periplasm] → glycine[cytosol] + H+[cytosol],
D-alanine[periplasm] + H+[periplasm] → D-alanine[cytosol] + H+[cytosol],
3-(3-hydroxyphenyl)propanoate[periplasm] + H+[periplasm] → 3-(3-hydroxyphenyl)propanoate[cytosol] + H+[cytosol],
L-lysine[periplasm] + H+[periplasm] → L-lysine[cytosol] + H+[cytosol],
4-aminobutanoate[periplasm] + H+[periplasm] → 4-aminobutanoate[cytosol] + H+[cytosol],
L-phenylalanine[periplasm] + H+[periplasm] → L-phenylalanine[cytosol] + H+[cytosol],
a drug[cytosol] + H+[periplasm] → a drug[periplasm] + H+[cytosol],
K+[cytosol] + H+[periplasm] → K+[periplasm] + H+[cytosol],
fosmidomycin[cytosol] + H+[periplasm] → fosmidomycin[periplasm] + H+[cytosol],
L-arabinose[cytosol] + H+[periplasm] → L-arabinose[periplasm] + H+[cytosol],
D-glucuronate[periplasm] + H+[periplasm] → D-glucuronate[cytosol] + H+[cytosol],
β-D-glucose 6-phosphate[periplasm] + phosphate[cytosol] → β-D-glucose 6-phosphate[cytosol] + phosphate[periplasm],
xanthosine[periplasm] + H+[periplasm] → xanthosine[cytosol] + H+[cytosol],
D-xylose[periplasm] + H+[periplasm] → D-xylose[cytosol] + H+[cytosol],
K+[periplasm] + H+[periplasm] → K+[cytosol] + H+[cytosol],
glycine betaine[periplasm] + H+[periplasm] → glycine betaine[cytosol] + H+[cytosol],
L-proline[periplasm] + H+[periplasm] → L-proline[cytosol] + H+[cytosol],
L-valine[cytosol] + H+[periplasm] → L-valine[periplasm] + H+[cytosol],
L-isoleucine[cytosol] + H+[periplasm] → L-isoleucine[periplasm] + H+[cytosol],
tellurite[out] + H+[out] → tellurite[in] + H+[in],
zinc hydrogenphosphate[out] + H+[out] → zinc hydrogenphosphate[in] + H+[in],
calcium hydrogenphosphate[periplasm] + H+[periplasm] → calcium hydrogenphosphate[cytosol] + H+[cytosol],
magnesium hydrogenphosphate[periplasm] + H+[periplasm] → magnesium hydrogenphosphate[cytosol] + H+[cytosol],
shikimate[periplasm] + H+[periplasm] → shikimate[cytosol] + H+[cytosol],
L-asparagine[periplasm] + H+[periplasm] → L-asparagine[cytosol] + H+[cytosol],
4-aminobutanoate[cytosol] + L-glutamate[periplasm] → L-glutamate[cytosol] + 4-aminobutanoate[periplasm],
N-acetylneuraminate[periplasm] + H+[periplasm]N-acetylneuraminate[cytosol] + H+[cytosol],
homoserine lactone[cytosol] + H+[periplasm] → homoserine lactone[periplasm] + H+[cytosol],
L-homoserine[cytosol] + H+[periplasm] → L-homoserine[periplasm] + H+[cytosol],
Mn2+[periplasm] + H+[periplasm] → Mn2+[cytosol] + H+[cytosol],
α-lactose[periplasm] + H+[periplasm] → α-lactose[cytosol] + H+[cytosol],
2-oxoglutarate[periplasm] + H+[periplasm] → 2-oxoglutarate[cytosol] + H+[cytosol],
sn-glycerol 3-phosphate[periplasm] + phosphate[cytosol]sn-glycerol 3-phosphate[cytosol] + phosphate[periplasm],
β-D-galactose[periplasm] + H+[periplasm] → β-D-galactose[cytosol] + H+[cytosol],
L-fucose[periplasm] + H+[periplasm] → L-fucose[cytosol] + H+[cytosol],
L-glutamate[periplasm] + 2 H+[periplasm] → L-glutamate[cytosol] + 2 H+[cytosol],
D-galactonate[periplasm] + H+[periplasm] → D-galactonate[cytosol] + H+[cytosol],
indole[periplasm] + H+[periplasm] → indole[cytosol] + H+[cytosol],
uracil[periplasm] + H+[periplasm] → uracil[cytosol] + H+[cytosol],
2 Na+[cytosol] + 3 H+[periplasm] → 2 Na+[periplasm] + 3 H+[cytosol],
Na+[cytosol] + 2 H+[periplasm] → Na+[periplasm] + 2 H+[cytosol],
L-tartrate[periplasm] + succinate[cytosol] → L-tartrate[cytosol] + succinate[periplasm],
Na+[periplasm] + L-leucine[periplasm] → Na+[cytosol] + L-leucine[cytosol],
Na+[periplasm] + L-valine[periplasm] → Na+[cytosol] + L-valine[cytosol],
Na+[periplasm] + L-isoleucine[periplasm] → Na+[cytosol] + L-isoleucine[cytosol],
D-galacturonate[periplasm] + H+[periplasm] → D-galacturonate[cytosol] + H+[cytosol],
L-aspartate[periplasm] + 2 H+[periplasm] → L-aspartate[cytosol] + 2 H+[cytosol],
2 Na+[periplasm] + L-glutamate[periplasm] → 2 Na+[cytosol] + L-glutamate[cytosol],
orotate[periplasm] + 2 H+[periplasm] → orotate[cytosol] + 2 H+[cytosol],
fumarate[periplasm] + 2 H+[periplasm] → fumarate[cytosol] + 2 H+[cytosol],
(S)-malate[periplasm] + 2 H+[periplasm] → (S)-malate[cytosol] + 2 H+[cytosol],
succinate[periplasm] + 2 H+[periplasm] → succinate[cytosol] + 2 H+[cytosol],
Na+[periplasm] + L-proline[periplasm] → Na+[cytosol] + L-proline[cytosol],
Na+[periplasm] + (R)-pantothenate[periplasm] → Na+[cytosol] + (R)-pantothenate[cytosol],
cytosine[periplasm] + H+[periplasm] → cytosine[cytosol] + H+[cytosol],
phosphate[periplasm] + H+[periplasm] → phosphate[cytosol] + H+[cytosol],
2-dehydro-3-deoxy-D-gluconate[periplasm] + H+[periplasm] → 2-dehydro-3-deoxy-D-gluconate[cytosol] + H+[cytosol],
L-rhamnose[periplasm] + H+[periplasm] → L-rhamnose[cytosol] + H+[cytosol],
uridine[periplasm] + H+[periplasm] → uridine[cytosol] + H+[cytosol],
thymidine[periplasm] + H+[periplasm] → thymidine[cytosol] + H+[cytosol],
inosine[periplasm] + H+[periplasm] → inosine[cytosol] + H+[cytosol],
2'-deoxyuridine[periplasm] + H+[periplasm] → 2'-deoxyuridine[cytosol] + H+[cytosol],
2'-deoxyinosine[periplasm] + H+[periplasm] → 2'-deoxyinosine[cytosol] + H+[cytosol],
2'-deoxycytidine[periplasm] + H+[periplasm] → 2'-deoxycytidine[cytosol] + H+[cytosol],
2'-deoxyadenosine[periplasm] + H+[periplasm] → 2'-deoxyadenosine[cytosol] + H+[cytosol],
cytidine[periplasm] + H+[periplasm] → cytidine[cytosol] + H+[cytosol],
adenosine[periplasm] + H+[periplasm] → adenosine[cytosol] + H+[cytosol],
a nucleoside[periplasm] + H+[periplasm] → a nucleoside[cytosol] + H+[cytosol],
a C4-dicarboxylate[periplasm] + 3 H+[periplasm] → a C4-dicarboxylate[cytosol] + 3 H+[cytosol],
succinate[cytosol] + (S)-malate[periplasm] → (S)-malate[cytosol] + succinate[periplasm],
succinate[cytosol] + L-aspartate[periplasm] → L-aspartate[cytosol] + succinate[periplasm],
succinate[cytosol] + fumarate[periplasm] → fumarate[cytosol] + succinate[periplasm],
glycolate[periplasm] + H+[periplasm] → glycolate[cytosol] + H+[cytosol],
(S)-lactate[periplasm] + H+[periplasm] → (S)-lactate[cytosol] + H+[cytosol],
Na+[cytosol] + H+[periplasm] → Na+[periplasm] + H+[cytosol],
γ-butyrobetaine[cytosol] + L-carnitine[periplasm] → γ-butyrobetaine[periplasm] + L-carnitine[cytosol],
L-arabinose[periplasm] + H+[periplasm] → L-arabinose[cytosol] + H+[cytosol],
enterobactin[cytosol] → enterobactin[extracellular space],
D-glucopyranose[periplasm] + H+[periplasm] → D-glucopyranose[cytosol] + H+[cytosol],
L-methionine[cytosol] + H+[periplasm] → L-methionine[periplasm] + H+[cytosol],
Fe2+[cytosol] + H+[periplasm] → Fe2+[periplasm] + H+[cytosol],
D-cycloserine[periplasm] + H+[periplasm] → D-cycloserine[cytosol] + H+[cytosol],
L-alanine[periplasm] + H+[periplasm] → L-alanine[cytosol] + H+[cytosol],
β-alanine[periplasm] + H+[periplasm] → β-alanine[cytosol] + H+[cytosol],
D-serine[periplasm] + H+[periplasm] → D-serine[cytosol] + H+[cytosol],
glycolate[periplasm] → glycolate[cytosol],
Na+[periplasm] + L-serine[periplasm] → Na+[cytosol] + L-serine[cytosol],
a drug[cytosol] + Na+[periplasm] → a drug[periplasm] + Na+[cytosol],
2 chloride[periplasm] + H+[cytosol] → 2 chloride[cytosol] + H+[periplasm],
Fe2+[periplasm] + H+[periplasm] → Fe2+[cytosol] + H+[cytosol],
guanosine[cytosol] + H+[periplasm] → guanosine[periplasm] + H+[cytosol],
agmatine[cytosol] + L-arginine[periplasm] → agmatine[periplasm] + L-arginine[cytosol],
acetate[periplasm] → acetate[cytosol],
L-cysteine[cytosol] ↔ L-cysteine[periplasm],
O-acetyl-L-serine[cytosol]O-acetyl-L-serine[periplasm],
inosine[cytosol] + H+[periplasm] → inosine[periplasm] + H+[cytosol],
ferric (2,3-dihydroxybenzoylserine)3[extracellular space] → ferric (2,3-dihydroxybenzoylserine)3[periplasm],
xanthine[periplasm] + H+[periplasm] → xanthine[cytosol] + H+[cytosol],
N-acetyl-β-neuraminate[periplasm] + H+[periplasm]N-acetyl-β-neuraminate[cytosol] + H+[cytosol]


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Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
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