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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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Escherichia coli K-12 substr. MG1655 Compound: acetyl phosphate

Synonyms: acetyl-P

Chemical Formula: C2H3O5P

Molecular Weight: 138.02 Daltons

Monoisotopic Molecular Weight: 139.987459781 Daltons

SMILES: CC(OP([O-])(=O)[O-])=O

InChI: InChI=1S/C2H5O5P/c1-2(3)7-8(4,5)6/h1H3,(H2,4,5,6)/p-2

InChIKey: InChIKey=LIPOUNRJVLNBCD-UHFFFAOYSA-L

Unification Links: CAS:19926-71-7 , ChEBI:22191 , ChemSpider:3394205 , HMDB:HMDB01494 , IAF1260:34318 , KEGG:C00227 , PubChem:4183249 , UMBBD-Compounds:c0049

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -303.08

Reactions known to both consume and produce the compound:

acetate formation from acetyl-CoA I :
acetate + ATP ↔ acetyl phosphate + ADP
acetyl-CoA + phosphate ↔ acetyl phosphate + coenzyme A

mixed acid fermentation :
acetate + ATP ↔ acetyl phosphate + ADP
acetyl-CoA + phosphate ↔ acetyl phosphate + coenzyme A

In Reactions of unknown directionality:

Not in pathways:
regulator of RpoS + acetyl phosphate = RssB-P + acetate

Enzymes activated by acetyl phosphate, sorted by the type of activation, are:

Activator (Mechanism unknown) of: malate dehydrogenase [Bologna07]

Enzymes inhibited by acetyl phosphate, sorted by the type of inhibition, are:

Inhibitor (Mechanism unknown) of: thiamine phosphate synthase [Kayama73, Kawasaki79, Comment 1]


References

Bologna07: Bologna FP, Andreo CS, Drincovich MF (2007). "Escherichia coli malic enzymes: two isoforms with substantial differences in kinetic properties, metabolic regulation, and structure." J Bacteriol 189(16);5937-46. PMID: 17557829

Kawasaki79: Kawasaki T (1979). "Thiamine phosphate pyrophosphorylase." Methods Enzymol 1979;62;69-73. PMID: 374983

Kayama73: Kayama Y, Kawasaki T (1973). "Purification and properties of thiaminephosphate pyrophosphorylase of Escherichia coli." Arch Biochem Biophys 1973;158(1);242-8. PMID: 4580841


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC13A.