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Escherichia coli K-12 substr. MG1655 Compound: CO2

Synonyms: carbonic anhydride, carbonic acid gas, carbon dioxide

Chemical Formula: CO2

Molecular Weight: 44.01 Daltons

Monoisotopic Molecular Weight: 43.989829244199996 Daltons

CO<SUB>2</SUB> compound structure

SMILES: C(=O)=O

InChI: InChI=1S/CO2/c2-1-3

InChIKey: InChIKey=CURLTUGMZLYLDI-UHFFFAOYSA-N

Unification Links: CAS:124-38-9 , ChEBI:16526 , ChemSpider:274 , HMDB:HMDB01967 , IAF1260:33506 , KEGG:C00011 , MetaboLights:MTBLC16526 , PubChem:280 , UMBBD-Compounds:c0131

Standard Gibbs Free Energy of Change Formation (ΔfG in kcal/mol): -92.26

Reactions known to consume the compound:

biotin biosynthesis from 8-amino-7-oxononanoate I :
CO2 + 7,8-diaminopelargonate + ATP → dethiobiotin + ADP + phosphate + 3 H+

Reactions known to produce the compound:

(5Z)-dodec-5-enoate biosynthesis :
a (3Z)-dec-3-enoyl-[acp] + a malonyl-[acp] + H+ → a (5Z)-3-oxo-dodec-5-enoyl-[acp] + a holo-[acyl-carrier protein] + CO2

1,4-dihydroxy-2-naphthoate biosynthesis I :
isochorismate + 2-oxoglutarate + H+ → 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + CO2

2-oxoglutarate decarboxylation to succinyl-CoA :
2-oxoglutarate + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + H+ → a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine + CO2

8-amino-7-oxononanoate biosynthesis I :
a pimeloyl-[acp] + L-alanine + H+ → 8-amino-7-oxononanoate + CO2 + a holo-[acyl-carrier protein]
a malonyl-[acp] methyl ester + a malonyl-[acp] + H+ → a 3-oxo-glutaryl-[acp] methyl ester + CO2 + a holo-[acyl-carrier protein]
a glutaryl-[acp] methyl ester + a malonyl-[acp] + H+ → a 3-oxo-pimeloyl-[acp] methyl ester + CO2 + a holo-[acyl-carrier protein]

allantoin degradation IV (anaerobic) :
ammonium + CO2 + ATP ← carbamoyl-phosphate + ADP + 2 H+

allantoin degradation to ureidoglycolate II (ammonia producing) :
allantoate + 2 H+ + H2O → S-ureidoglycine + ammonium + CO2

aminopropylcadaverine biosynthesis , L-lysine degradation I :
L-lysine + H+CO2 + cadaverine

arginine dependent acid resistance , L-arginine degradation III (arginine decarboxylase/agmatinase pathway) , putrescine biosynthesis I :
L-arginine + H+CO2 + agmatine

β-alanine biosynthesis III :
L-aspartate + H+ → β-alanine + CO2

cis-vaccenate biosynthesis :
a palmitoleoyl-[acp] + a malonyl-[acp] + H+ → a 3-oxo-cis-vacc-11-enoyl-[acp] + CO2 + a holo-[acyl-carrier protein]

coenzyme A biosynthesis I :
R-4'-phosphopantothenoyl-L-cysteine + H+ → 4'-phosphopantetheine + CO2

conversion of succinate to propanoate :
(R)-methylmalonyl-CoA + H+ → propanoyl-CoA + CO2

cyanate degradation :
cyanate + hydrogen carbonate + H+ → carbamate + CO2
carbamate + 2 H+ → ammonium + CO2

D-malate degradation :
(R)-malate + NAD+CO2 + pyruvate + NADH

demethylmenaquinol-8 biosynthesis I :
all-trans-octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate + H+CO2 + demethylmenaquinol-8 + diphosphate

fatty acid biosynthesis initiation I :
acetyl-CoA + a malonyl-[acp] + H+ → an acetoacetyl-[acp] + CO2 + coenzyme A

fatty acid biosynthesis initiation II , superpathway of fatty acid biosynthesis initiation (E. coli) :
a malonyl-[acp] + an acetyl-[acp] + H+ → a holo-[acyl-carrier protein] + an acetoacetyl-[acp] + CO2

fatty acid biosynthesis initiation III :
a malonyl-[acp] + an acetyl-[acp] + H+ → a holo-[acyl-carrier protein] + an acetoacetyl-[acp] + CO2
a malonyl-[acp] + H+ → an acetyl-[acp] + CO2

fatty acid elongation -- saturated :
a malonyl-[acp] + a 2,3,4-saturated fatty acyl-[acp] + H+ → a holo-[acyl-carrier protein] + a 3-oxoacyl-[acp] + CO2

formate to dimethyl sulfoxide electron transfer , formate to nitrite electron transfer , formate to trimethylamine N-oxide electron transfer , nitrate reduction III (dissimilatory) :
formate[periplasmic space] + a menaquinone[inner membrane] + 2 H+CO2[periplasmic space] + a menaquinol[inner membrane] + H+[periplasmic space]

gluconeogenesis I :
(S)-malate + NADP+CO2 + pyruvate + NADPH

Reactions known to both consume and produce the compound:

cyanate degradation :
hydrogen carbonate + H+CO2 + H2O

glycine cleavage :
glycine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + H+ ↔ a [glycine-cleavage complex H protein] N6-aminomethyldihydrolipoyl-L-lysine + CO2

L-valine biosynthesis :
2 pyruvate + H+ ↔ (S)-2-acetolactate + CO2

Not in pathways:
pyruvate + 2 an oxidized ferredoxin + coenzyme A ↔ acetyl-CoA + CO2 + 2 a reduced ferredoxin + H+

In Reactions of unknown directionality:

Not in pathways:
2-oxoglutarate + SucB-lipoate = SucB-S-succinyldihydrolipoate + CO2
oxalyl-CoA + H+ = CO2 + formyl-CoA
pyruvate + thiamin diphosphate + H+ = 2-(α-hydroxyethyl)thiamine diphosphate + CO2
oxalosuccinate + H+ = 2-oxoglutarate + CO2
pyruvate + lipoamide + H+ = S-acetyldihydrolipoamide + CO2
an acyl-[acyl-carrier protein] + a malonyl-[acp] + H+ = a 3-oxoacyl-[acp] + CO2 + a holo-[acyl-carrier protein]
L-allo-threonine + NADP+ = aminoacetone + CO2 + NADPH
formate + an oxidized hydrogenase 3 = CO2 + a reduced hydrogenase 3

In Transport reactions:
CO2[periplasmic space]CO2[cytosol]

In Redox half-reactions:
acetate[in] + CO2[in] + 2 H+[in] + 2 e-[membrane] → pyruvate[in] + H2O[in] ,
CO2[out] + H+[out] + 2 e-[membrane] → formate[out]


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of EcoCyc: Nucleic Acids Research 41:D605-12 2013
Page generated by SRI International Pathway Tools version 19.0 on Tue Sep 1, 2015, BIOCYC14B.